complete the sentence with the correct form of the verb ser el sr morales rubio
Tài liệu Supply the correct form of the verbs1 docx
Ngày tải lên :
23/01/2014, 07:20
... live in a snake.
14. My brother managed to kill the snake just at the time when I were almost exhausted.
Supply the correct form of the verbs
1. Cats could fly if they (have) wings.
2. If Peter ... (not,want) to live in a snake.
14. My brother managed to kill the snake just at the time when I (be) almost exhausted. If
he (be) a little late, I (kill) by the snake.
15. Had I know you were ill, ... snake.
14. My brother managed to kill the snake just at the time when I (be) had been almost
exhausted. If he (be) had been a little late, I (kill) would have been killed by the snake.
15. Had...
- 5
- 1K
- 3
Báo cáo khoa học: The pharmacological chaperone isofagomine increases the activity of the Gaucher disease L444P mutant form of b-glucosidase docx
Ngày tải lên :
22/03/2014, 21:20
... increase both the absolute level and
the relative specific activity of the mutant enzyme
in vivo. This observation is in agreement with the pre-
vious finding that IFG can increase the relative specific
activity ... LCLs compared with
fibroblasts because of the ability of IFG to more freely
diffuse into and out of LCLs grown in suspension
compared with the monolayers of adherent fibroblast
cells, thus resulting ... observed in only one of the 18 patients
who completed the study. The results of this trial pro-
vide preliminary proof -of- concept that IFG can
increase GCase activity and improve the pathophysio-
logical...
- 21
- 281
- 0
Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx
Ngày tải lên :
07/03/2014, 21:20
... mutation of Arg46 had the dual
effect of (a) decreasing agonist affinity and (b) promoting
the agonist-induced active conformation due to the loss of a
stabilizing constraint on the ground state of the ... compared to the wildtype Arg46, with the
precise value depending on the identity of the substituent
amino acid (Fig. 5). These data establish that the mutant
receptors are much less likely than the wildtype ... Results
The effect of systematic substitution of Arg46
on agonist binding
The structural requirements of the residue at position 46 in
the N-terminus of the V
1a
R (Fig. 1) were investigated, with
respect...
- 8
- 487
- 0
Economic Impact of the Abolition of the Milk Quota Regime – Regional Analysis of the Milk Production in the EU – doc
Ngày tải lên :
18/03/2014, 00:20
... on average, with +35.5% in the EU-10 and
+13.8 in the EU-15. This excess supply makes the net trade position of the EU-27 stronger
towards the Rest of the World. Within the EU there is a quite ... implications of the dairy policy reform, with an explicit focus on
regional effects in the EU-27 of a milk quota abolition in the year 2015.
Specification of the Model
The CAPRI model is an agricultural ... positions which depend on the production trends for each MS and the distribution of
demand amongst them.
17
These trends of the baseline are in line with the market outlook for the dairy sector (European...
- 127
- 569
- 0
Báo cáo khoa học: Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization pptx
Ngày tải lên :
23/03/2014, 07:20
... localization of
SRPK1. Coexpression of SRPK1 could modulate
cellular localization of the N protein, suggesting that
the N protein is a substrate of SRPK1 in cells
(Fig. 6). Phosphorylation of the transmissible ... possibly phosphorylated by SRPK1.
Phosphorylation of multiple serines within the
RS motif
The RS motif of the SARS-CoV N protein is divergent
from that of canonical SR proteins and contains fewer
RS ... HA-tagged SRPK1 were transiently coex-
pressed in HeLa cells. In the presence of overexpressed
SRPK1, the N protein was unable to localize to SGs,
even after arsenite treatment of the cells (Fig....
- 12
- 432
- 0
Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf
Ngày tải lên :
23/03/2014, 17:22
... between the projection of the tilt of the z axis on the xÂ,y plane (dened direction of tilt of z and the x axis), and j % a + c denes the
location of the rhombic (x, y) axes. The orientation of the ... [16,17], and the detailed structures provide import-
ant information on the novel Hb. The Tyr66(E7) ring is
oriented out of the heme pocket in both forms with the
Tyr32(B10) in one of the structures ... consistent with the % 10° tilt of the
Fe-CN vector from the heme normal to avoid van der waals
overlap with the Tyr32(B10) O
g
. The location of the
rhombic axes, j % 50 ± 10°,isinagreementwiththe
expectations...
- 14
- 504
- 0
Báo cáo khoa học: Structure of the exceptionally large nonrepetitive carbohydrate backbone of the lipopolysaccharide of Pectinatus frisingensis strain VTT E-82164 doc
Ngày tải lên :
23/03/2014, 18:20
... possible only in the case of an a-configuration
of residue D, linked to O4 of Kdo C, as follows from
molecular modeling. The unusual position of the H3
signals of residue D in product 1a (aswellasin1b, ... analysis of com-
pound 4 was the determination of the anomeric configur-
ation of Kdo D (see above).
Mild acid hydrolysis of the LPS with subsequent borohy-
dride reduction and separation of the products ... in 7b compared with 7a (Table 1) because of the b-
effect of the acetylation. Acetylation of 7b was confirmed by
ESI MS data, which gave the expected mass of 3221.4 Da.
The spectra of oligosaccharide...
- 11
- 326
- 0
Báo cáo khoa học: Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1 doc
Ngày tải lên :
23/03/2014, 21:20
... spectrophotometer. The electroche-
mical potential of the solution was measured using a Hanna
pH 211 meter coupled to a Pt/Calomel electrode (Thermo-
Russell Ltd) at 25 °C. The electrode was calibrated using the
Fe
3+
/Fe
2+
EDTA ... of electron transfer
from 2 electron-reduced FAD/NADPH domain to
NADP
+
, the FAD/NADPH domain was titrated to the
2-electron level with sodium dithionite. The reduced FAD/
NADPH domain was then ... the
reconstituted activity is % 3% of that in full length NR1,
similartotheratioachievedwithCPRdomains.
To explore further the influence of the hydride transfer
step on catalytic activity of the...
- 12
- 439
- 0
Báo cáo khoa học: Structure of the O-polysaccharide fromProteus myxofaciens Classification of the bacterium into a newProteusO-serogroup pptx
Ngày tải lên :
23/03/2014, 21:20
... LPS)
[5,6]. The serological specificity of the bacteria is defined
by the structure of the O-specific polysaccharide chain
(O-antigen) of the lipopolysaccharide. On the basis of the
O-antigens, the strains ... the structure of the
O-polysaccharide of P. myxofaciens and serological pro-
perties of the LPS of this strain, including cross-reactivity
with several other Proteus and Providencia strains with
Correspondence ... 4.58/4.01.
In the
13
C NMR spectrum of the polysaccharide, a
relatively large b effect ()2 p.p.m.) was observed on the C3
Fig. 1.
13
C NMR spectrum of the O-polysac-
charide of P. myxofaciens.
Fig....
- 7
- 345
- 0
Báo cáo khoa học: Expression and characterization of soluble forms of the extracellular domains of the b, c and e subunits of the human muscle acetylcholine receptor pot
Ngày tải lên :
30/03/2014, 10:20
... shown as a black bar at the C-terminus of some c
ECD(s). (B) Relative yields of the different c ECD constructs. All
yields were expressed as a percentage of the yield of the non-
tagged c1–218 ... data
from electron images of the AChR found in large
amounts in the electric organ of the marine ray,
Torpedo californica [3]. The acquisition of the crystallo-
graphic structure of the mollusc ... to verify the identity of the inserts.
Yeast transformation and dot-blot screening
of positive clones
Plasmids (10 lg) encoding the b1–221 ECD (with or with-
out the FLAG epitope) and the various...
- 12
- 394
- 0
Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx
Ngày tải lên :
31/03/2014, 09:20
... photosynthetic growth, the
insertion of PufX in the core LH1–RC complex, the stability
of the dimers and the kinetics of flash-induced reduction of
cytochrome b
561
of the cytochrome bc
1
complex. Deletion
of ... in the
light of our results. The presence in vitro of a less stable
dimer in the mutant PufXD
2)7
neither affects the photo-
synthetic capability of the bacteria nor the efficiency of
exchange of ... an inhibitory effect
on the formation of the LH1 complex. This result suggests
that the central core of the PufX protein is responsible of the
break in the continuity of the LH1 ring in vivo [14],...
- 9
- 547
- 0
Review of the Literature Regarding Critical Information Needs of the American Public
Ngày tải lên :
02/06/2014, 09:39
... theory of reasoned
action, the health belief model, the extended parallel process model, and the trans-theoretical
model. Theories providing insight into the design of health campaigns are also ...
concluding with a discussion of the role of the Internet.
The health literature on media is primarily focused on the health cognition and beliefs
and beliefs of individuals, and the media and ... on information at the individual level.” Among the dimensions of
inequality are “a) access to and use of information channels and services, b) attention to and
processing of health information,...
- 124
- 377
- 0
Báo cáo sinh học: " Viroporin potential of the lentivirus lytic peptide (LLP) domains of the HIV-1 gp41 protein" docx
Ngày tải lên :
18/06/2014, 18:20
... http://www.virologyj.com/content/4/1/123
Page 9 of 14
(page number not for citation purposes)
Proposed models of the C-terminus of TMFigure 5
Proposed models of the C-terminus of TM. Proposed models of LLP domains in the context of TM ... could have the effect of stabi-
lizing the Env trimers and/or the resulting transmembrane
pore that could then be formed by the LLP-1 and -2
domains. The location of the LLP-3 domain on the inner
leaflet ... and parallel association with the inner leaflet of the
lipid bilayer. On the other hand, the LLP domains may
possess different activities in the different cell types that it
infects, or there may...
- 14
- 365
- 0