coa—the citric acid cycle
Tài liệu Báo cáo Y học: Evolution of the enzymes of the citric acid cycle and the glyoxylate cycle of higher plants pdf
... nuclear-encoded proteins into novel evolutionary compartments In eukaryotes, the citric acid cycle (Krebs cycle, or tricarboxylic acid cycle) is an important pathway in that it is the primary source of electrons ... tricarboxylic acid cycle J Bacteriol 182, 2844 Ó FEBS 2002 Evolution of the tricarboxylic acid cycle (Eur J Biochem 269) 881 25 Krebs, H.A & Johnson, W.A (1937) The role of citric acid in intermediate ... acid cycle, and glyoxylate cycle, there are 21 different subunits involved, the sequence similarity patterns of which can be summarized in 19 Ó FEBS 2002 Evolution of the tricarboxylic acid cycle...
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CHAPTER 4: THE CITRIC ACID AND OXIDATIVE PHOSPHORYLATION ppt
... character of the citric acid cycle; and Understand the reactions that replenish citric acid cycle intermediates 13 CELLULAR LOCATION Both prokaryotic and eukaryotic cells use the citric acid cycle to ... Cytochrome C- comlex IV Citric Acid Cycle INTRODUCTION The citric acid cycle is a central metabolic pathway that completes the oxidative degradation of fatty acids, amino acids, and monosaccharides ... groups that enter the citric acid cycle; Trace the conversion of substrates to products through each of the citric acid cycle s eight reactions and understand how flux through the cycle is regulated;...
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Báo cáo khoa học: Characterization of isocitrate dehydrogenase from the green sulfur bacterium Chlorobium limicola A carbon dioxide-fixing enzyme in the reductive tricarboxylic acid cycle ppt
... (1987) Carbon assimilation pathways in sulfate-reducing bacteria II Enzymes of a reductive citric acid cycle in the autotrophic Desulfobacter hydrogenophilus Arch Microbiol 148, 218–225 Shiba, ... Beh, M., Strauss, G., Huber, R., Stetter, K.-O & Fuchs, G (1993) Enzymes of the reductive citric acid cycle in the autotrophic eubacterium Aquifex pyrophilus and in the archaebacterium Thermoproteus ... limicola, as a CO2-fixing enzyme in RTCA cycle The enzyme IDH from C limicola was revealed to be a monomeric enzyme with a molecular mass of 80.5 kDa The deduced amino -acid sequence of Cl-idh gene showed...
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Influence of charge mode on the capacity and cycle life of lead±acid battery negative plates ppsx
... case the cycle life of the electrodes is very short The fast charge of the electrode yields a bit longer cycle life The reason for the steep decline in capacity and hence for the end of cycle life ... I1 1:0 C A, the cycle life of the model electrode is short On charge with I1 0:5 C A, the ME reaches 60 mAh g capacity for about 191 cycles Evidently, both the capacity and cycle life depend ... corresponds to 100% DOD Initially, the MEs were subjected to three capacity cycles at a 20-h rate of discharge The electrodes were cycled until the 60 mAh g capacity was reached Results and discussion...
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Báo cáo y học: "validation of the ERS standard citric acid cough challenge in healthy adult volunteers" pps
... [8] Stock solution of citric acid M (Royal Hallamshire Hospital, Sheffield) was serially diluted in physiological saline to produce incremental concentrations of citric acid (1, 3, 10, 30, 100, ... 3.51(-0.64,7.65) -6.89(-15.21,1.42) 0.03* Response to citric acid R5 resistance at Hz; R10 resistance at 10 hz; × reactance; Δ, change in measurement after citric acid Data represented as mean, with 95% confidence ... effect of citric acid on the IOS measures following the Mefar challenge Whilst studying the cough challenge methodologies we wished to clarify whether, as it does in animals [22], citric acid administration...
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Six Sigma and the Product Development Cycle
... Six Sigma and the Product Development Cycle This page intentionally left blank Six Sigma and the Product Development Cycle Graham Wilson AMSTERDAM • BOSTON • HEIDELBERG • LONDON ... x Culture What is six sigma? 12 The transformation that is six sigma 27 The product development cycle 48 Quality function deployment 69 Taguchi’s techniques 107 Statistical process control 179 ... success-making ingredients for business Of course, the 1970s did not Six Sigma and the Product Development Cycle have a monopoly on them (It is sometimes interesting hearing someone describing a stylish...
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Adsorption characteristics of Ni2+ ion onto the diethylenetriaminepentaacetic acid-melamine / polyvinylidene fluoride blended resin
... blended resin, the adsorptiondesorption process was repeated for four cycles with the adsorption performance analyzed in each cycle The adsorption was conducted with 1.0 g of resin in 200 mL of ... blend resin in four adsorption/desorption cycles The results show that the blended resin still has good adsorption/desorption capability After four cycles, the adsorption capacity of the blended ... Adsorption and desorption of Ni2+ on Na-montmorillonite: Effect of pH, ionic strength, fulvic acid, humic acid and addition sequences J Applied Clay Science 2008, 39(3-4), 133-141 [6] Su H.J., Chen...
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The Portlet Life Cycle
... Boykma.Com 2840ch03.qxd 7/13/04 12:44 PM Page 71 The Portlet Life Cycle Summary In this chapter, we have discussed the life cycle of a portlet The portlet container calls the init() method on ... 12:44 PM Page 44 Chapter Overview It shouldn’t come as much of a surprise to find that the life cycle of a portlet is broadly the same as that of a servlet Servlets are generally responsible for ... generally responsible for rendering fragments of pages, so there’s an obvious correlation The life cycle of a portlet therefore breaks down into the following stages: Creation of the portlet Processing...
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The conditions in Africa and Eurasia during the last glacial cycle
... relief Africa and Eurasia during the last glacial cycle 141 The relative influence of wet and arid cycles will have varied during glacial– interglacial cycles (Narcisi, 2001) In southern Europe, in ... glacial cycle the desert was even more extensive than it is today (Grove & Warren, 1968; Gaven et al., 1981; Swezey, 2001) Superimposed on these cycles are millennial-scale late Quaternary cycles, ... Atlantic related to the surging of the Laurentide Ice Sheet Africa and Eurasia during the last glacial cycle 137 through the Hudson Strait (Heinrich, 1988; Bond & Lotti, 1995; Alley et al., 1999) There...
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Tài liệu Báo cáo khoa học: Modulation of the enzymatic efficiency of ferredoxin-NADP(H) reductase by the amino acid volume around the catalytic site pptx
... proline, aspartic acid, serine or alanine Simple and double FNR mutants of amino acids C266 and L268 were obtained and characterized It was observed that alteration of the amino acid volume decreases ... amino acid groups introduced by the mutations was determined following the standard radii and volumes calculated by Tsai et al [32] direct effect of mutations that replace native amino acids ... amino acids C266, G267 and L268 The data support the hypothesis that the aromatic interaction between the flavin, Y308 and the nicotinamide of NADP+ is precisely tuned by selecting amino acids...
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Tài liệu Báo cáo khoa học: Implication of the glutamine synthetase ⁄glutamate synthase pathway in conditioning the amino acid metabolism in bundle sheath and mesophyll cells of maize leaves doc
... for individual amino acid contents are of the same order of magnitude as those of the total amino acid contents for glutamine (C), glutamic acid (D), asparagine (E), aspartic acid (F), alanine (G), ... and amino acids (CI) in maize leaves collected every h during a 16 h light h dark cycle Nitrate and ammonium contents represent the mean from ve independent plants standard error Amino acid contents ... assimilated in the light (Fig 1B) The major amino acids in the leaves were alanine (2639%), glycine (2640%), glutamic acid (614%), serine (812%) and aspartic acid (416%) in both the light and dark (Fig...
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Tài liệu Báo cáo Y học: Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms pdf
... involves the side chains of the amino acids in positions 53 and 56 in a helix B, 186 in b strand 3A, and position 334 in b strand 5A (Fig 1; the numbering of amino acids in PAI-1 is according to the ... use of either the Thermo Sequenasee II dye terminator cycle sequencing kit (Amersham Pharmacia Biotech AB) or the ABI PRISMe dye terminator cycle sequencing ready reaction kit (PerkinElmer) Recombinant ... region, having a Gly in position 56 and a Gln in position 334 (Fig 1) This composition of amino acids in positions 53/56/334 is present in only 5% of the serpins, for example PN-1, RASP-1, TSA2004,...
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Báo cáo khoa học: The oleic acid complexes of proteolytic fragments of a-lactalbumin display apoptotic activity pdf
... form the molten globule in acid solution Eur J Biochem 286, 4324–4333 ´ Cury-Boaventura MF, Pompeia C & Curi R (2004) Comparative toxicity of oleic acid and linoleic acid on Jurkat cells Clin ... poly-a-amino acids (i.e poly-Lys and poly-Arg) This a-LA interaction was shown to be driven by electrostatic forces [29,30] Therefore, the active species in the cell may be the whole protein–fatty acid ... toxic fatty acid [33] Results Preparation of complexes of a-LA fragments with OA Two procedures were followed to prepare the OA–fragment complexes, namely by simple mixing the Oleic acid complexes...
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Báo cáo Y học: ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity potx
... was accomplished by the addition of 0.4 mL MilliQ water and 0.5 mL ninhydrin reagent [1.2 M citric acid/ 1.5% (w/v) ninhydrin in 2-methoxyethanol, : 2] The mixture was then vortexed for 15 s, ... N-terminal amino -acid sequence of the 19-kDa band (from pTYB11) was shown to be MSDSTPKTPR, identical to that expected for the N-terminus of ORF6 This was Ó FEBS 2002 ORF6 from the clavulanic acid gene ... be used as an alternative to the widely used amino -acid acylases [34], in particular for the resolution of racemic mixtures of certain amino acids with side chains containing polar groups The...
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Báo cáo khoa học: Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex doc
... cycloheximide early in the cell cycle (before RP) immediately suffer a long delay in the cell division cycle; (b) cells treated late in the division cycle finish the current cycle similar to untreated ... the cell cycle to the control of the RP would be important for drug target identification studies and for understanding the action mechanism of existing, RP affecting drugs Abrupt cell cycle transitions ... cycle autonomously [2,3] Cells in the G1phase that have not yet passed RP, monitor their environment and own size to determine whether they are ready to commit to S-phase entry and division cycle...
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The Economics of Small Business Finance: The Roles of Private Equity and Debt Markets in the Financial Growth Cycle potx
... next about the financial growth cycle of small business.4 The Financial Growth Cycle of Small Business Small business may be thought of as having a financial growth cycle in which financial needs ... which sources of finance become important at different points in the financial growth cycle, and the points in the cycle at which different types of funding are shown to begin and end are not intended ... 7-8 years of a business’ life cycle, theh increases thereafter their data not include trade credit, their results may understate the dependence throughout the life cycle Their results suggest that...
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Báo cáo Y học: Synthesis and turn-over of the replicative Cdc6 protein during the HeLa cell cycle potx
... restricted to specific phases of the cell cycle, HeLa cells were arrested by a double-thymidine procedure at the G1 phase/S phase transition, and then released into the cycle after removing excess thymidine ... next cycle (Fig 2A) Cytoplasmic and chromatin extracts were immunoprecipitated with specific antibodies and transferred to nitrocellulose membranes Immunostaining showed that cells in all cell cycle ... the budding yeast cell cycle Curr Biol 10, 231–240 23 Liang, C & Stillman, B (1997) Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants...
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Báo cáo khoa học: Suppression of nuclear factor-jB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles pot
... acid composition of the particles modulates this effect Earlier studies on the effects of free fatty acids on NF-jB activity in macrophages have also suggested that different types of fatty acids ... eicosapentaenoic acid and docosahexaenoic acid, which are found in fish oil, downregulate LPSinduced NF-jB DNA binding and p65–NF-jB expression, and increase IjBa expression and docosahexaenoic acid and ... macrophages with essential 18-carbon fatty acids Ann Nutr Metab 51, 155–162 45 Lee JY, Sohn KH, Rhee SH & Hwang D (2001) Saturated fatty acids, but not unsaturated fatty acids, induce the expression of...
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Báo cáo khoa học: PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast pdf
... palmitic and stearic acid represent 5–8% and 32–49% of the total fatty acid esterified to PI, respectively [6–8] By contrast, PI from plants contains much more palmitic acid than stearic acid as the major ... and saturated fatty acid groups to the sn-1 position [11] (see also below) Nevertheless, in yeast, the difference between palmitic ( 30–40% of total fatty acids) and stearic acid content ( 10–15% ... 0.2% of total PI fatty acids compared to 10.3 ± 0.1% in wild-type) This decrease in the stearic acid content of PI was mainly compensated for by an increase in the palmitoleic acid content, and was...
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