... after ingestion of a glucose load of 75 g a plasma glucose value of 11 .1 mmol/L) or more is abnormal *Glycosylated hemoglobin (HbA1c) Different cutoofs( HBA1c value of 7.0%, as the cutoff for detecting ... G3p25,frequency of allele 85%., key regulator of adipocyte development and function KCNJ 11 (Potassium inwardly rectifying channel, subfamily J, member 11 ) 11 p15, E23K., 1. 2 ,40% Component of the beta-cell ... confirmation) • Hemoglobin A1c ADA 19 97 DIAGNOSTIC CRITERIA FOR T2D •Symptoms ofdiabetes and RPG > (11 .1 mmol/L) or FPG > (7.0 mmol/L) • 2-hour plasma • FPG, glucose > (11 .1 mmol/L) during an OGTT...
... analysis of pathogenesis of changes in central nervous system in human diabetes? Folia Neuropathol.; 41( 3) :16 7-74 CNSComplicationsofDiabetesMellitusType (Type Diabetic Encephalopathy) 17 [ 31] ... Apr 19 ; 490 (1- 3): 18 7-97 [2] Tripathi BK, Srivastava AK (2006) Diabetes mellitus: complications and therapeutics Med Sci Monit Jul ;12 (7):RA130-47 CNS ComplicationsofDiabetesMellitusType (Type ... ComplicationsofDiabetes Mellitus, Edited by Oluwafemi O Oguntibeju p cm ISBN 978-953- 51- 0833-7 Contents Preface VII Chapter CNSComplicationsofDiabetesMellitusType (Type Diabetic Encephalopathy) ...
... retinopathy (per 10 0 patient years) 14 11 Glycated haemoglobin (%) Fig 2 .1 Rate of development of background retinopathy per 10 0 patient years in different classes of HbA1C Berlin ... number of studies of patients with typediabetes has suggested that as many as 20% of patients not CHAPTER • RISK FACTORS 50 5.4–8.5 8.6 10 .0 10 .1 11 .5 11 .6–20.8 Incidence (%) 40 P
... no conflict of interest exists References 10 11 12 13 14 15 16 17 Griendling KK, Fitzgerald GA Oxidative stress and cardiovascular injury Animal and human studies Circulation 2003; 10 8: 2034–2040 ... perspective on an old paradigm Diabetes 19 99; 48: 1 9 Brownlee, M Biochemistry and molecular cell biology ofdiabeticcomplications Nature 20 01; 414 : 813 –820 Jakus V The role of free radicals, oxidative ... therefore diabetic patients may have a defective intracellular antioxidant response that causes diabeticcomplications (11 -13 ) The combination of the low levels of antioxidants and raised levels of...
... MACROVASCULAR COMPLICATIONSOFDIABETES 0 .12 Cumulative mortality Kaplan-Meier rates 42 Ramipril Placebo 0 .10 0.08 RRR = 37% ( 21- 51) P = 0.00 01 0.06 0.04 0.02 0.00 500 10 00 Days of follow-up 15 00 2000 ... 19 98; 8: 17 2 18 1 Wardlaw JM, Warlow CP, Counsell C Systemic review of evidence on thrombolytic therapy for acute ischaemic stroke Lancet 19 97; 350: 607– 614 Vascular Complicationsof Diabetes: ... cause of ED in the non -diabetic population People with diabetes are not immune to this typeof failure and anxiety may be exacerbated by their awareness of ED as a complication ofdiabetes 51 52...
... Study ofDiabetic Retinopathy IV Diabetic macular oedema Ophthalmology 19 84; 91: 14 64 14 74 Per cent with macula oedema 15 2 40 30 20 10 0 10 15 20 Duration (years) 25 30 35 Fig 17 .1 Frequency of ... prevalence of macular oedema was approximately 70% (Table 17 .1) The prevalence of maculopathy also increases with duration of diabetes, and is higher in type compared with typediabetes (Figs 17 .1 & 17 .2) ... number of persons with macular oedema status or in either or both eyes) × 10 0 Table 17 .1 Relationship ofdiabetic retinopathy with macular oedema* and duration ofdiabetes (Wisconsin, HAS -1, 19 80–82)...
... Threshold 12 0 Mean Systolic BP 13 6 +/- mmHg 12 :00 AM 10 :00 PM 8:00 PM 6:00 PM 4:00 PM 2:00 PM 12 :00 PM 10 :00 AM 8:00 AM 6:00 AM 4:00 AM 2:00 AM 12 :00 AM 11 0 International Diabetes Center 200 12 5 12 :00 ... Rates of Coronary Heart Disease Nondiabetic vs .Type Diabetes Subjects 50 45 (% over years) CHD Events No History of CVD 40 Prior MI 30 18 .8 20 10 20.2 3.5 No DiabetesDiabetes N = 13 73 N = 10 59 ... 24.4 18 .6 20 15 11 .9 10
... validated [1, 15]: 038.x (septicaemia), 790.7 (bacteraemia), 11 7.9 (disseminated fungal infection), 11 2.5 (systemic candidiasis) and 11 2. 81 (disseminated fungal endocarditis) Typeof infection ... Epidemiol 19 92, 45: 613 - 619 18 Charlson M, Szatrowski TP, Peterson J, Gold J: Validation of a combined comorbidity index J Clin Epidemiol 19 94, 47 :12 45 -12 51 19 Frank JA, Nuckton TJ, Matthay MA: Diabetes ... by grant AA R 01- 014 435 from the National Institutes of Health References 10 11 12 13 Martin GS, Mannino DM, Eaton S, Moss M: The epidemiology of sepsis in the United States from 19 79 through 2000...
... http://www.annals-general-psychiatry.com/content/6 /1/ 25 12 13 14 15 16 17 18 19 20 21 and improving the standard of care J Clin Psychopharmacol 2004, 24(5 Suppl 1) :S7-S14 Hirschfeld RM, Kasper S: A review of the evidence for ... The patient was a 55-year-old married female, mother of two healthy grown-up children, with a history of type- 1 DM since the age of 11 For her diabetes, she was initially treated with insulin (Novolente) ... study J Clin Psychiatry 2006, 67 :10 55 -10 61 Lehman R, Pavlicek V, Spinos GA, Weber M: Islet transplantation in type- 1diabetesmellitus Ther Umsch 2005, 62:4 81- 486 Folstein MF, Folstein SE, McHugh...