cmp amp imp gmp tmp and xmp
Báo cáo y học: "The CRIT framework for identifying cross patterns in systems biology and application to chemogenomics" ppt
Ngày tải lên :
09/08/2014, 22:24
... drugs labeled as high and low, and the denominator is simply the difference between the standard error for high and low Welch’s t-statistic was used to compute P values, and proteins with P < ... transcription factors and their associated targets in the yeast regulatory network, relationships between gene properties such as expression and binding status and breast cancer type, and finally using ... balls(x) and non-binding genes as black balls (n) The total number of differentially expressed genes (ER+ vs ER-) represents the sample withdrawn and x of these are also ER targets (that is sampled...
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Tài liệu Báo cáo khoa học: Molecular characterization of Arabidopsis thaliana PUF proteins – binding specificity and target candidates doc
Ngày tải lên :
18/02/2014, 06:20
... NRE(A+B)); and in both Box A and B, NRE(A–B–) (C) Qualitative analysis of LacZ reporter activation in the interaction of APUM-2 and APUM-7 with NRE WT and NRE mutants The iron responsive element RNA and ... human and mouse possess two; and Drosophila and Dyctiostelium have only one member [5] Recently, new studies have revealed the presence of ten, two and one homologs in Trypanosome, Plasmodium and ... and NRE can be extended to the remaining group I proteins, we tested the interaction of APUM-1, APUM-3, APUM-4, APUM-5 and APUM-6 with wild-type and mutant NREs Qualitative (data not shown) and...
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Báo cáo khoa học: Nuclear localization of human spermine oxidase isoforms – possible implications in drug response and disease etiology pptx
Ngày tải lên :
07/03/2014, 05:20
... existence of SMO5 in human normal and tumor cell lines SMO5 cDNA was subcloned and sequenced, and active protein was produced, purified and assayed for kinetic properties and substrate specificities NCI-H157 ... and tumor necrosis factor-a, respectively, has been linked to increased ROS production and DNA damage [29,30], thus implicating SMO as a potential molecular link between chronic inflammation and ... to inclusion bodies, and therefore was denatured and refolded prior to analysis All SMO5 protein production and purification steps were performed in parallel with SMO ⁄ PAOh1 and PAOh4 proteins...
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Báo cáo khoa học: "Learning to Translate with Source and Target Syntax" pot
Ngày tải lên :
07/03/2014, 22:20
... bitexts, and one on two billion words of English These were smoothed using modified Kneser-Ney (Chen and Goodman, 1998) and stored using randomized data structures similar to those of Talbot and Brants ... translation tends to hamper translation quality by imposing too many constraints during both grammar extraction and decoding, we have shown that using both source and target syntax improves translation ... is a pair of subtrees of a training example and the frontiers of γ and α form a phrase pair, then (γ, α) is a rule in G • If (γ2 , α2 ) ∈ G, (γ3 , α3 ) ∈ G, and (γ1 , α1 ) is an elementary tree...
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ECONOMIC AND SOCIAL CONSEQUENCES OF DRUG ABUSE AND ILLICIT TRAFFICKING doc
Ngày tải lên :
08/03/2014, 06:20
... iron and steel and motor vehicles (2.8 per cent and 5.3 per cent respectively) and approximately the same size as the international trade in textiles (7.5 per cent), oil and gas (8.6 per cent) and ... synthetic drugs manufactured clandestinely are the amphetamine-type stimulants (ATS) The most widely used ATS are methamphetamine and amphetamine; a number of other amphetamine-type stimulants have ... Bolivia, Colombia and Peru; heroin in Myanmar, Pakistan and Thailand; methamphetamine in Far-East and South-East Asian countries; fenetylline in several countries of the Arabian peninsula and methaqualone...
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Báo cáo khoa học: "Bridging Morpho-Syntactic Gap between Source and Target Sentences for English-Korean Statistical Machine Translation" pot
Ngày tải lên :
17/03/2014, 02:20
... any English words, and can simply and easily be removed by referring to their POS information The unaligned words are case particles, final endings, and auxiliary particles, and they call these ... 2005; Xia and McCord, 2004; Zwarts and Dras, 2007) Some reordering approaches have given significant improvements in performance for translation from French to English (Xia and McCord, 2004) and from ... For example, from the following sentence, we can select as pseudo words a subjective particle and an objective particle , and insert them after the corresponding dependents Eugene and...
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Báo cáo khoa học: "Resolving Translation Ambiguity and Target Polysemy in Cross-Language Information Retrieval" potx
Ngày tải lên :
17/03/2014, 07:20
... meanings (Lai and Lin, 1987): (1) sport, (2) exercise, (3) movement, (4) motion, (5) campaign, and (6) lobby Each corresponding English word may have more than one sense For example, "exercise" ... and Polysemy Resolution Models In the recent works, Ballesteros and Croft (1998), and Bian and Chen (1998) employ dictionaries and co-occurrence statistics trained from target language documents ... these words be CW~, CW2, , and C W m Assume the corresponding English translations of C, CW~, CW2, , and CWm are E, EW,, E W , , and EWm, respectively EWe, EW2, , and EWm form an augmented translation...
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the effect of the hydrothermal treatment with aqueous naoh solution on the photocatalytic and photoelectrochemical propertiesof visible light-responsive TiO2thin films
Ngày tải lên :
20/03/2014, 13:11
... patterns of Vis-TiO2/Ti and NaOH(X)-Vis-TiO2/Ti and (b) the expanded XRD patterns of (a) (2u = 5–158) Fig XPS spectra of the Ti 2p (right) and Na 1s (left) peaks of the Vis-TiO2/Ti and NaOH(X)-Vis-TiO2/Ti ... (Laforet Engineering, XD50D) and the evolved H2 and O2 were analyzed by a gas chromatograph (GC, G2800-T, Yanaco) with a thermal conductivity detector (TCD) Results and discussion Photoelectrochemical ... Current–potential curves of Vis-TiO2/Ti and NaOH(5)-Vis-TiO2/Ti electrodes under UV (l ! 300 nm) and visible light (l ! 420 nm) irradiation Light source: 500 W Xe lamp M Matsuoka et al / Catalysis...
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financial statement analysis Abbott Laboratories and Target
Ngày tải lên :
25/03/2014, 12:18
... 23.83% Property and equipment Land Buildings and improvements Fixtures and equipment Computer hardware and software Construction-inprogress Accumulated depreciation Property and equipment, net ... accessories and shoes Home furnishings and décor includes furniture, lighting, kitchenware, small appliances, home décor, bed and bath, home improvement, automotive and seasonal merchandise such ... retail and credit card Target is known for their operations in general merchandise and food items Their general merchandise segment includes household essentials, electronics, apparel and accessories,...
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MASS SPECTROMETRY IN DRUG METABOLISM AND DISPOSITION docx
Ngày tải lên :
28/03/2014, 10:20
... Lee, and Guodong Chen Characterization of Impurities and Degradants Using Mass Spectrometry Mike S Lee and Mingshe Zhu Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and ... hydroxylamines and oximes and secondary amines to N-hydroxy and nitrone products Aromatic amines and amides are not substrates Thioethers can be oxidized to sulfoxides; and thiols, thioamides, and thiocarbamates ... be used as a teaching and/ or reference tool to delineate and understand the “why” and “how” with regard to the many creative uses of mass spectrometry in drug metabolism and disposition studies...
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Báo cáo khoa học: Role of the plasma membrane leaflets in drug uptake and multidrug resistance ppt
Ngày tải lên :
29/03/2014, 08:20
... well as anionic drugs and dyes, but also neutral ⁄ basic amphipathic drugs and even oxyanions Previously, it has been assumed that the oxyanions arsenite and antimonite and the neutral ⁄ basic ... membrane is unstirred and dense with proteins Moreover, TMRM and anticancer drugs, such as anthracyclines, are positively charged and therefore bind to acidic groups in proteins and membranes Thus, ... lines MRP1 transports, on the one hand, organic anions, such as glutathione conjugates, and, on the other hand, basic hydrophobic drugs, such as daunorubicin and vincristine [14] It has been suggested...
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For Medicare Advantage Plans, Medicare Advantage Prescription Drug Plans, Prescription Drug Plans, and 1876 Cost Plans ppt
Ngày tải lên :
29/03/2014, 23:20
... name(s) or brand(s) of the co-branding entity or entities on its marketing materials to signify a business arrangement Co-branding arrangements allow a plan sponsor and its co-branding partner(s) ... communication materials are delivered and received timely and appropriately, and important materials are identified in a way that members understand their importance Have a process for automatic mailing ... Drug Program’s (NCPDP’s) “Pharmacy and/ or Combination ID Card” standard This standard is based on the American National Standards Institute ANSI INCITS 284-1997 standard titled Identification Card...
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Báo cáo khoa học: "Combining Source and Target Language Information for Name Tagging of Machine Translation Output" ppt
Ngày tải lên :
31/03/2014, 00:20
... this simple method can improve the English NER result substantially (Table 5-1), especially for recall, confirming our intuition We checked the errors produced by this simple merge method, and ... previous token F4 and F5 are used to help resolve the type conflicts, and F6 and F7 to resolve boundary conflicts When there is a conflict, we need the confidence information from both ET and English ... and William J 2005 HMM Word and Phrase Alignment for Statistical Machine Translation Proc Human Language Technology Conference and Empirical Methods in Natural Language Processing Fei Huang and...
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fragment based drug discovery and x-ray crystallography
Ngày tải lên :
29/05/2014, 23:54
... Davies and Ian J Tickle Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening 61 Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey, and Roderick E Hubbard Combining NMR and ... Potent and Selective BACE-1 Inhibitors Daniel F Wyss, Yu-Sen Wang, Hugh L Eaton, Corey Strickland, Johannes H Voigt, Zhaoning Zhu, and Andrew W Stamford 83 Combining Biophysical Screening and X-Ray ... Marsh, Sandra Greive, and Marko Hyvonen Fragment Screening and HIV Therapeutics 181 Joseph D Bauman, Disha Patel, and Eddy Arnold Fragment-Based Approaches and Computer-Aided...
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báo cáo hóa học: " Simultaneous buried object detection and imaging technique utilizing fuzzy weighted background calculation and target energy moments on ground penetrating radar data" potx
Ngày tải lên :
21/06/2014, 00:20
... B-scan data, in SPIE Defense and Security Symposium, Detection and Remediation Technologies for Mines and Mine like Targets IX Orlando (2004), 905–912 TG Savelyev, LV Kampen, H Sahli, J Sachs, M ... Defense and Security Symposium, Detection and Remediation Technologies for Mines and Mine like Targets, Orlando, USA (13-17 April 2009) DJ Daniels, P Curtis, O Lockwood, Classification of landmines ... Development of dual sensor hand-held detector, in SPIE Defense and Security Symposium, Detection and Remediation Technologies for Mines and Mine like Targets, Orlando, ABD, (5-9 April 2010) M...
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Báo cáo hóa học: " Target estimation algorithm design using quantity data and target feature" pptx
Ngày tải lên :
21/06/2014, 03:20
... multiple-model estimator and neural algorithm for radar system Int J Innov Comput Inform Control 31(2):4809–4817 (2009) B Sugandi, H Kim, JK Tan, S Ishikawa, Real time tracking and identification of ... processing is adopted to identify the target feature And then the computation algorithm will calculate the similarity between the image of measurement and image of existing targets The process of main ... main works for conducting image processing is shown in Figure 1, and the descriptions are given as follows (1) Gray transformation and spatial filtering: In order to effectively determine the attribute...
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DRUG DISCOVERY AND DEVELOPMENT – PRESENT AND FUTURE pptx
Ngày tải lên :
27/06/2014, 17:20
... Preface Drug discovery and development process aims to make available medications that are safe and effective in improving the length and quality of life and relieving pain and suffering However, ... success hinges on improving the predictivity of efficacy and toxicity, which in turn depends on innovations and having reliable and robust biomarkers and using appropriate tools and methodologies ... predisposition and prognosis to diseases as well as therapy and life-style regime Importance of such individual variations in health and disease is an important basic principle of ayurveda and was underlined...
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Báo cáo khoa học: "SemiFDG-PET/CT imaging for staging and target volume delineation in conformal radiotherapy of anal carcinoma" potx
Ngày tải lên :
09/08/2014, 08:22
... (66.7%) cases and disease-free and overall survival (DFS and OS) rates were 66.7% and 77.8% respectively Acute and late toxicity higher than grade (RTOG/EORTC) was observed in 7/27 (25.9%) and 1/27 ... study and drafted the manuscript MEM, LT, CB and LD were involved in data collection and review EM, BC and MC worked on analysis of data EI and MB participated in the design of the study and contributed ... was given by cisplatin and 5-fluorouracil in 15 cases and mytomicin and 5-fluorouracil in cases Statistical analysis PET-GTV and PET-CTV were respectively compared to CT-GTV and CT-CTV by Wilcoxon...
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Báo cáo y học: " Injection drug use and patterns of highly active antiretroviral therapy use: an analysis of ALIVE, WIHS, and MACS cohort" ppt
Ngày tải lên :
10/08/2014, 05:20
... one NRTI and at least one PI and at least one NNRTI, 3) an abacavir- or tenofovir-containing regimen with at least NRTIs, 4) a regimen containing ritonavir and saquinavir and one NRTI, and no NNRTIs ... there is no impact of reported use of injection drugs on HAART modification These data imply efforts to simplify and increase potency of antiretroviral regimens have been successful at improving ... contributions to conception and design, acquisition of data, and analysis and interpretation of data; 2) have been involved in drafting the manuscript; and 3) have read and given approval of the...
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