clinical features and natural history of multiple sclerosis the nature of the beast

Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke docx

Ngày tải lên : 18/02/2014, 11:20

... spectrum of conditions caused by the occlusion or hemorrhage of blood vessels supplying the brain, and is one of the major causes of death and disability in developed countries [3] The initial ... from the subventricular zone, and inhibition of these MMPs also blocked the movement of these neuroblasts, originally headed towards damaged brain [61] Beyond VEGF and MMPs, the concept of biphasic ... experimental and clinical studies have focused on MMP-2 and MMP-9 because they interact with t-PA and there are simple and reproducible assays to detect their levels via gelatin zymography or ELISAs Of...

9
704
0

Textbook of Sports Medicine Basic Science and Clinical Aspects of Sports Injury and Physical Activity pot

Ngày tải lên : 15/03/2014, 09:20

... potential role in the promotion of health and prevention of life-style diseases in individuals of all ages Furthermore, lately the medical eld has gained improved understanding of the use of physical ... Furthermore, the invention and development of magnetic resonance imaging in the early s, and the renement and general availability of ultrasound investigation during the late s, has increased the ... The study and quantitative measurement of the intensity of dyspnea had to wait rstly for the introduction of the eld of psychophysics by Stevens [], and secondly for the development of appropriate...

829
1.2K
0

Novel Insights on Chronic Kidney Disease, Acute Kidney Injury and Polycystic Kidney Disease Edited by Soundarapandian Vijayakumar pdf

Ngày tải lên : 23/03/2014, 17:20

... thickness, and corticomedullary differentiation; the presence, volume, and structure of the bladder; any evidence of dilatation elsewhere in the urinary tract; the presence of other abnormalities of the ... and there has been a significant interest and progress in the understanding of these diseases Two often overlooked topics, the role of extracellular matrix abnormalities in PKD cystogenesis and ... define RSW by supporting data and review the pathophysiology of RSW, the derivation and evolution of the controversy over the relative prevalence of SIADH and RSW, and methods to differentiate...

144
368
0

Sport, Professionalism and Pain: Ethnographies of injury and risk doc

Ngày tải lên : 30/03/2014, 02:20

... Kleinman (1992) (the professional, the popular and the folk) enable a useful understanding of the context of the development of sports medicine It is in the context of the popular and folk arenas ... than the other unions, the Welsh certainly suffered the most at the hands of professionalism This suffering took the form of players heading to the north of England to exploit their talent in the ... engines 53 The body and social theory 53 Pain and the body 65 Summary 69 vi PART II Pain, injury and the culture of risk 70 71 The concept of pain 72 Medical practice and the nature of pain 77...

235
455
0

báo cáo hóa học: " The Dutch version of the knee injury and osteoarthritis outcome score: A validation study" pdf

Ngày tải lên : 18/06/2014, 22:20

... complaints These patients were asked whether they understood all items and whether they had any problems with the formulation of the items on the Dutch version of the KOOS questionnaire None of the ... measurement error of a score, expressed in the unit of measurement of the instrument [19] The SEM was calculated as the square root of the sum of the between administration variance and the residual ... with the generic SF-36 and the VAS for pain Hypotheses were formulated about the expected magnitude and direction of relationships between the subscales of the KOOS questionnaire and the other...

11
442
0

báo cáo hóa học: " Interleukin-1alpha expression precedes IL-1beta after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues" pdf

Ngày tải lên : 19/06/2014, 22:20

... design and analysis of the study and wrote the manuscript AD carried out the surgeries, contributed to the design and analysis of the study and wrote the manuscript All authors read and approved the ... confocal slice at the level of the nucleus The fold enrichment of IL-1α and GFP in the nucleus were calculated as follows: Fold enrichment = MFI (nucleus) / MFI (whole cell) The fold enrichment ... family of cytokines, IL-1α and IL-1β, are considered the major effectors of injury, and inhibiting their signalling with the IL-1 receptor antagonist (IL-1Ra) is protective in experimental models of...

16
425
0

Health and Quality of Life Outcomes BioMed Central Research Open Access Knee injury and pptx

Ngày tải lên : 20/06/2014, 15:20

... includes the WOMAC, patients were also sent the SF-36 and questions regarding background data The Swedish version LK 1.0 of the KOOS [9], including the Swedish version LK 1.0 of the WOMAC [10], and the ... studies of the KOOS [6,9] and the adaptation of the KOOS to foot- and ankle related problems [21] where the intraclass correlation coefficients have ranged from 0.70 (ADL subscale of the foot- and ... replacement These functions are not assessed by the WOMAC Responsiveness The KOOS subscale knee-related QOL had the highest effect size of all subscales of the KOOS and the WOMAC (Table 5) The relative...

10
329
0

báo cáo hóa học: " A cohort study of short-term functional outcomes following injury: the role of pre-injury sociodemographic and health characteristics, injury and injury-related healthcare" pot

Ngày tải lên : 20/06/2014, 15:20

... a result of their injury Participants were also asked for their assessment of the seriousness of the injury in terms of threat to life and threat of disability The questions were: “At the time, ... the same household and their relationship with the respondent [8] We assessed the highest educational qualification using the two questions from the Census [8] The first of these determines the ... (combining ‘Some’ and ‘Extreme’ problem responses) with the six outcomes of interest (the five dimensions of the EQ-5D, and cognitive ability) and the independent measures to be assessed For the six binary...

12
472
0

INJURY AND SKELETAL BIOMECHANICS docx

Ngày tải lên : 28/06/2014, 10:20

... extension of the knee joint between the half and the end of standing phase) The results also showed no difference in the width of the base and the position of the thorax during walking cycles The speed ... Th1 and L5 and then 25 women were measured form the 16th week of pregnancy to birth and again two months after birth The side photography was taken of the area of the thorax and the profile of the ... with the behaviour of a car on a road bend The sharper the bend and the smaller the radius r, the bigger the car speed V and the bigger force acting on the car, increasing the risk of falling off...

226
200
0

Báo cáo lâm nghiệp: " The role of glutamine synthetase, glutamate synthase and glutamate dehydrogenase in ammonia assimilation by the mycorrhizal fungus Pisolithus tinctorius" ppt

Ngày tải lên : 09/08/2014, 04:20

... Inhibition of GS and glutamate synthase blocked the synthesis of glutamine and glutamate, respectively When GS was inhibited, some glutamine was synthesised initially, and this may have accounted for the ... detected and found to be relatively constant throughout the period of growth (4-14 d) (Fig 2b) GS activity was generally higher during the initial period of rapid growth (5-10 d) and decreased thereafter ... glutamine (Fig 3c) The size of the glutamate pool did not increase over h, thus there was no incorporation of ammonia into glutamate by GDH After h the glutamine concentration peaked and remained stable,...

5
360
0

Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus ppt

Ngày tải lên : 10/08/2014, 05:21

... in most of the GABAAR found in the hippocampus, and were chosen based on their relative abundance and their potentially important contributions in GABAAR function When the expression of these proteins ... neuronal excitability and pharmacological responsiveness after TBI These studies, therefore, support the hypotheses that TBI alters the constituent proteins of the GABAAR and that these alterations ... anesthetized under 3.5% isoflurane in a carrier gas consisting of 70% N2O and 30% O2 The surgical incision was re-opened and the animals were connected to the fluid percussion device Animals in the...

11
424
0

$Báo cáo y học: "Traumatic vertebral artery dissection in an adult with brachial plexus injury and cervical spinal fracture" pptx$

Báo cáo y học: "Traumatic vertebral artery dissection in an adult with brachial plexus injury and cervical spinal fracture" pptx

Ngày tải lên : 10/08/2014, 10:20

... (inside the transverse foramina) and the V3 (between the C1 and the base of the skull) [7] The latter is usually injured in minor trauma Clay Cothren et al [8] in a large series concluded that the ... in both T1- and T2weighted images of the vertebral artery on the right side There was intramural methaemoglobin plus occlusion of the lumen, but there was no intraluminal thrombus There was no ... MRI of the cervical spine MRI of the cervical spine T2-weighted image shows high signal intensity (white arrow) of the right vertebral artery There is an intramural thrombus plus occlusion of the...

4
371
0

Báo cáo y học: "Cholestatic jaundice, acute kidney injury and acute pancreatitis secondary to the recreational use of methandrostenolone: a case report" potx

Ngày tải lên : 11/08/2014, 00:23

... contributions GR and AC were major contributors in writing the manuscript EY and PK analyzed and interpreted the patient data regarding the patient’s presentation and provided the clinical care of the patient ... patient MP performed the histological examination of the liver biopsy and prepared the figure for the manuscript All authors contributed to the writing of the manuscript and approved the final version ... due to the unethical nature of administering these drugs in the doses usually taken by patients who use them for aesthetic or athletic purposes As a result, with the increasing use of these drugs,...

5
274
0

báo cáo khoa học: " The evolution of the Global Burden of Disease framework for disease, injury and risk factor quantification: developing the evidence base for national, regional and global public health action" pps

Ngày tải lên : 11/08/2014, 18:20

... system, and often the mortality data collected are incomplete and of poor quality [5] 'Verbal autopsy' procedures, using structured interviews with the family of the deceased, provide a history of ... the true pattern of disease and injury in the community due to biases arising from the nature of conditions typically treated in hospitals and the ability of sectors of the population to afford ... missing data and to assess the reliability of data, and the use of a common metric to summarise disease burden from both diagnostic categories of the International Classification of Disease and Injuries,...

8
381
0

Báo cáo y học: " The first description of severe anemia associated with acute kidney injury and adult minimal change disease: a case report" ppsx

Ngày tải lên : 11/08/2014, 19:21

... unusual nature of the case, advised on content of the paper and critically reviewed the content of the paper NG provided clinical information and critically reviewed the content of the paper EF interpreted ... role since the patient developed ARF prior to the contrast administration, and the patient had hemodialysis shortly after the dye exposure Unlike the scenario in the majority of cases of MCD with ... at any time during the first 14 days of the initiation of renal replacement therapy In contrast, in our case, high-dose EPO was initiated at the onset of ARF and days before the significant drop...

6
316
0

báo cáo khoa học: " Differential patterns of reactive oxygen species and antioxidative mechanisms during atrazine injury and sucrose-induced tolerance in Arabidopsis thaliana plantlets" ppsx

Ngày tải lên : 12/08/2014, 03:20

... Consequently, repression of these transcripts and decrease of the corresponding enzyme activities in the presence of atrazine might accentuate the effects of H2O2 accumulation by reduction of ascorbate recycling, ... hours to the different control and treatment media described above (M, S, MA and SA) Plantlets, prior to the transfer and at the end of the treatment, were immersed and infiltrated in the dark ... sucrose, whether combined or not with atrazine, therefore reestablished the basal level of transcripts (Table 3) and of global activity (Fig 4), thus avoiding the repressive effects of the herbicide...

18
265
0

Báo cáo y học: " The role of γδ T cells in airway epithelial injury and bronchial responsiveness after chlorine gas exposure in mice" pps

Ngày tải lên : 12/08/2014, 15:20

... concentration of 430 ppm The brief exposure employed in the current study is likely within the range of possible accidental exposures of human subjects The factors influencing the rate of epithelial ... airway epithelial damage and shedding Furthermore, this study provided evidence of oxidant stress and nitrosylation of proteins in airway epithelial cells and alveolar macrophages [8] Porcine and rabbit ... likely of key importance in determining the short and long term consequences of chlorine induced airway dysfunction The γδ T cells are trophic for the epithelium and potentially could influence the...

11
300
0

Báo cáo y học: "Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines" doc

Ngày tải lên : 12/08/2014, 18:20

... YCL conducted all the experiments, analyzed the data, conceived of and designed the studies, confirmed data analysis and wrote the manuscript CE and AJG conceived of and designed the studies, confirmed ... at 260 nm and 280 nm to measure the concentration of RNA and the purity of the extract Reverse transcription of equal quantities of RNA (2.5 μg) from each condition was performed using the AmpliTaq-Gold ... significantly reduced the release of GAGs and increased the sulfate incorporation rate The effects of DEX on biosynthesis were significantly reversed by the presence of RU486, though the increase in...

15
290
0

Báo cáo khoa học: "Science review: Mechanisms of beta-receptor stimulationinduced improvement of acute lung injury and pulmonary edema" ppt

Ngày tải lên : 12/08/2014, 20:20

... to the pulmonary endothelium Production of IL-8 and other chemokines within the lung leads to recruitment of neutrophils and of other leukocytes into the interstitial and alveolar spaces of the ... inflammatory response in the lung in ALI decreases the capacity of the epithelium to remove edema fluid from the distal airspaces of the lung Disruption of the integrity of the alveolar–capillary ... alveolar–capillary barrier is comprised of capillary endothelium and of alveolar epithelium The alveolar epithelium is composed of type I cells (90–95%) and of type II cells (5–10%) Type II cells...

9
303
0

Báo cáo y học: "Human T-cell leukemia virus type I infects human lung epithelial cells and induces gene expression of cytokines, chemokines and cell adhesion molecules" ppt

Ngày tải lên : 13/08/2014, 05:21

10
215
0