... of Polo-Like Kinase Evaluation ofthe results obtained inthe two systems showed deregulation ofthe same pathways in human SCLC andin that induced experimentally by the E6/E7 oncoproteins of ... release the E2F transcription factor, subsequently leading to progression ofthecell into the S-phase [14] Furthermore, E7 binds to inhibitors of cyclin-dependent kinases (p16, p21), increasing the ... immortalization of primary human keratinocytes in vitro [22] In squamous cell carcinomas ofthe head and neck (HNSCC), the E6 and E7 oncoproteins function through multiple interactions with two cardinal cellular...
... specific stem cell therapies An example is the use of stem cell therapy inthe treatment of myocardial infarction (MI) One ofthe main safety concerns is the occurrence of arrhythmias [98,104] These ... genetic reprogramming, the used viruses can integrate into thecell genome Consequently the cells may contain multiple viral integration sites in their genomes The use of retroviruses and lentiviruses ... the viral safety ofthe stem cell based medicinal product Most ofthe ESC lines used today have been generated for basic research, with the application in humans not yet in mind These cell lines...
... the indications andthe best HAs to choose Looking to the future, minimally invasive surgery will further drive the use of topical HA inthe urologic field They offer promising employ inthe ... bleeding, for tumors of cm or less of diameter We propose to make use of those different way of achieving haemostasis considering the satisfying results, their handling and their efficacy, inthe ... bleeding and nephrotoxicity, suggests a possible employ for FloSeal inthe treatment of devastating renal injuries [14,15] Furthermore, a porcine model investigating on the use of FloSeal and...
... existence of cells that contain both mucin and secretary granules within their cytoplasm Therefore we agree with the hypothesis ofthe dual entodermal and neuroendocrine origin of goblet cell carcinoid ... among the groups of goblet cells infiltrating the submucosa and muscle layer of appendix Similar clusters of goblet cells and immunoreative endocrine cells were also found inthe wall ofthe ceacum ... study the hormonal nature of goblet cell carcinoids, the location of hormones andthe phenotype of endocrine cells Another useful method for simultaneous revealing of mucin secretion and endocrine...
... education, official training and informal on -the- job training Informal on-thejob training is likely to correlate with the skill content ofthe job, and hence MNEs offer more of this when they are ... Sanchez-Paramo and Schady (2003) explain increases in wage inequality across countries and within countries, in Argentina, Brazil, Chile, Colombia and Mexico They find evidence of increases inthe demand ... to introduce the latest technology requiring further training Thus, continued participation in export markets requires continuous skill upgrading through training There is also increasing interest...
... concerning the kinetics and properties ofthe enzyme More strikingly, we show a novel role ofthe PPase enzyme inthedevelopmentand molting process of A suum larvae in vitro constructed in UniZap ... immunohistochemical staining), and that the inhibition of PPasecatalyzed PPi hydrolysis by these inhibitors, is likely to prevent the synthesis ofthe new cuticle from the hypodermis and/ or ecdysis ofthe old ... presence of increasing concentrations of inhibitors for 10 days, andthe number of molting larvae was determined Molting was manifested by shedding ofthe L3 cuticle Results Identification of cDNA...
... of CSR 1.2.4 The model of sustainable developmentin Vietnam: Figure 1.4 - The model of CSR in Vietnam 14 The carrying out of construction and operation concept of "sustainable development" in ... the strength ofthe enterprise, the weaknesses ofthe business 21 The specific target for analysing ofthe inside and outside factorsin the enterprises from which we form strategic business development ... designed and used models to analysis and synthesis of theory, strategy and business development at the small and medium enterprises inthe village of BacNinh province, Vietnam The research applied the...
... disruption inthe homeostasis between food intake and energy expenditure, andthe subsequent deposition of excess fatty acids into fat cells inthe form of triglycerides, leads to thedevelopmentof ... Despite the pivotal role of obesity and dyslipidemia inthedevelopmentofthe metabolic syndrome and heart disease, the functional interactions between adipose tissue andthe lipid and lipoprotein ... of these mice worsened the glucose tolerance and insulin sensitivity ofthe ApoE) ⁄ ) · Ay ⁄ + mice, and triggered obesity, indicating that circulating ApoE is involved in increased adiposity and...
... an otherwise inaccessible world of other, andin so doing, to see that they are included inthe reflection ofthe public mirror ofthe nanotechnology initiative One interesting aspect ofthe ... Values in Nanotechnology Research and Design: The Case ofthe Aerogel 140 Timothy 142 Meaning Making 160 The Making of Meaning 160 The Negotiation of Self inTechnology 162 Intentionality and Responsibility ... who they understand themselves to be, what they aspire to achieve, and how they are conceiving the use of their research in nanotechnology inthe design and determination of future human and...
... resources andthe role of education and training inthedevelopmentof high-quality human resources in Vietnam at present - Clarifying the real situation ofthe role of education and training inthedevelopment ... the training of pupils and students and to the discovery of, fostering, training, using, and attracting the talented people Nguyen An Ninh (2009), Book Bringing into Full Play the Potential of ... Studying the realities ofthe role of education and training inthedevelopmentof high-quality human resources in certain higher institutions in Vietnam at present - In term of time scope, the thesis...
... associated with thedevelopmentofthe knowledge-based economy inthe Province of Thua Thien-Hue from now to the year 2020 The object and scope ofthe study 3.1 Studying Object ofthe thesis The dissertation ... own work and to the best of my knowledge Data and materials used inthe thesis are real with obvious origins; findings in this thesis are studied results ofthe writer AUTHOR OFTHE THESIS Ha ... situation ofthedevelopmentof human resources and achievements, the shortcomings and their causes, offers viewpoints and proposes solution groups for HRD during the period of industrialization and...
... independent variable inthe analysis and could not explain the results even though the infection rate andthe duration of mechanical ventilation were not increased inthe obese group Studies of critically ... analytic cohort Outcome variables The primary outcomes of interest were the risk ofthedevelopmentof acute organ failure within three years ofthe baseline examination, in- hospital mortality related ... prepared in collaboration with investigators ofthe ARIC study and does not necessarily reflect the opinions or views ofthe ARIC study or the NHLBI The coauthors had full access to all ofthe data in...
... exploring the frequency of linking words through the data collection 2.1 Frequency of linking words in IELTS Speaking and Writing In finding the frequency of linking words used in IELTS spoken and ... courses and for obtaining the requiring score inthe writing and speaking section ofthe IELTS Linking words are crucial in writing and speaking in that they help readers / listeners recognize the ... coherence, linking words and general information of IELTS speaking and writing Also, they are drawn from the findings and discussions in chapter 3.1 In terms of coherence and cohesion in IELTS writing...
... courses and for obtaining the requiring score inthe writing and speaking section ofthe IELTS Linking words are crucial in writing and speaking in that they help readers / listeners recognize the ... 2: Findings and Discussions provides a summary of major findings ofthe low and high frequencies of different kinds of linking words and some comparisons between IELTS writing task and task and ... and then read through the answers to find the link between sentences and work out the employment of linking words in terms of semantic function used And thus we have to tabulate the use of linking...
... resources andthe role of education and training inthedevelopmentof high-quality human resources in Vietnam at present - Clarifying the real situation ofthe role of education and training inthedevelopment ... Marxism – Leninism, Ho Chi Minh Thoughts, standpoints, paths ofthe Party and policies ofthe State of Vietnam on thedevelopment strategies of education and training, andthedevelopmentof human ... taking into account as follows: Awareness ofthe role of high-quality human resources andof education and training inthedevelopmentof these human resources ofthe Party, the State and the...
... the identification of binding partners for a known protein by expressing the protein in fusion with BD domain and then screening proteins in fusion with AD It also allows the identification of ... ofthe given cell type, the quality and quantity of DNA taken up by the cells, the cytotoxicity ofthe transfection reagent andthe condition ofthe cells These limitations have restricted the ... domain in its C-terminal portion and a death domain (DD) in its Nterminal portion Activation of TLR or IL-1R recruits MyD88 to the receptor The TIR domain of MyD88 binds to the TIR domains of...
... Incident in 1989.5 David Lee examined the role of NGOs in promoting legal reform in China and concluded that a strong NGO sector can facilitate thedevelopmentof rule of law in China andthe role of ... as the starting point for counting the time limit? Or as long as the applicant does not withdraw the application, the starting point will be the beginning ofthe promulgation ofthe law? If the ... economic and social developmentof citizens; (5) Secret issues inscientific technology; (6) Secret issues in activities of maintaining national security andthe investigation of criminal activity; and...
... erns of cultures — the poli tical and intellectual culture s ofthe Zhou d ynast y and t he Warri ng St ates peri od Speci fi call y, uti litari anism was the mainst ream thinking duri ng the ... ABSTRACT Xun Zi was one of t he great est C onfuci an thinkers inthe pre-Qin peri od The purpose of thi s t hesis is to i nterpret the basi c charact er of his philosoph y First of all, it argues ... in which Xun Zi lived, yet his broader sense of utilit ari anism inherited and absorbed the el ement s V of rites and musi c from the Zhou politi cal culture Xun Zi ’s empiricism reflect ed the...