cholinesterase inhibitors in the treatment of dementia associated with parkinson apos s disease
báo cáo khoa học: "Angiogenesis inhibitors in the treatment of prostate cancer" pdf
Ngày tải lên :
10/08/2014, 22:21
... molecules that inhibit tyrosine kinases, primarily by binding the ATP binding domain, has led to investigation of tyrosine kinase inhibitors as angiogenesis inhibitors In general, because tyrosine kinases ... recommendations discouraging treatmentdiscontinuation for isolated PSA progression in the absence of clinical progression, it is possible that bevacizumab was discontinued prematurely on the basis of PSA ... PSA progression may not be the best reflection of disease activity in the setting of sorafenib treatment Finally, a European study also reported their Phase II results with sorafenib as a single...
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Báo cáo y học: "Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis" pot
Ngày tải lên :
12/08/2014, 19:22
... (Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis [PROWESS]) [4] Severe sepsis was defined in all protocols as the presence of known or suspected infection, the presence of ... all-cause mortality (i.e 28 days after the start of infusion) was assessed for all studies, except study F1K-MC-EVBC, in which 7-day mortality was assessed for a subset of patients (non-US) For this ... the instrumentation of large blood vessels or highly vascular organs The incidence of non-pro- Table Rates of serious bleeding events classified as during the infusion period and postinfusion...
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Báo cáo y học: "Heel raises versus prefabricated orthoses in the treatment of posterior heel pain associated with calcaneal apophysitis (Sever’s Disease): study protocol for a randomised controlled trial" ppt
Ngày tải lên :
10/08/2014, 21:24
... recorded during the study The adverse events may include incidents such as skin reactions (e.g., blisters or rashes) from the prefabricated orthoses or heel lifts Analysis The intervention factors will ... doi:10.1186/1757-1146-3-3 Cite this article as: James et al.: Heel raises versus prefabricated orthoses in the treatment of posterior heel pain associated with calcaneal apophysitis (Sever s Disease) : study protocol ... at no cost All participants within this group will be given standardised shoe wearing in instructions Schools within the study area allow the students to wear athletic footwear as the chosen footwear...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
Ngày tải lên :
25/10/2012, 10:51
... decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distribution in patients with ascites [52] Hepatitis C virus (HCV) infection is ... decrease, deaths from renal disease are on the rise [65] As more of our patients develop renal disease, psychiatrists must be aware of the effects of psychotropics on the kidneys, as well the effects ... hemodialysis (HD) and should be administered in a single post-dialysis dose of 300–600 mg Lithium levels should be checked pre-dialysis and 2–3 hrs following the post-dialysis dose There is a case...
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Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"
Ngày tải lên :
25/10/2012, 11:40
... angles of the dural opening The most significant step involves constructing small supporting pillars on the bilateral sides of the vessels as they pass the edge of the dural window (the pillars ... intervals The process was repeated in parallel rows of incisions so that each incision in one row was adjacent to an intact dural bridge in the rows on either side The same course was then performed, ... Following removal of part of the skull, they performed dural incisions in a stellate fashion In this step, it is important that entrance points of major vessels are close to the midpoint between the...
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Báo cáo y học: "Godoy & Godoy technique in the treatment of lymphedema for under-privileged populations."
Ngày tải lên :
26/10/2012, 09:39
... in press, show that the association of these activities with compression mechanisms maintain losses achieved during lymph drainage 8,9 First, the working pressures of the main muscle groups of ... physiotherapists, a seamstress to make the compression stockings and social assistants In the evaluations of the patients, the multidisciplinary team is also important in the development of research ... require the services of a professional seamstress Even so, many patients have been trained to produce their own compression stockings, sleeves or gloves The use of these compression mechanisms gives...
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Báo cáo y học: " Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"
Ngày tải lên :
26/10/2012, 09:48
... assessments as indicated Clinical assessments as indicated Clinical assessments as indicated 30 60 Treatment Period (Days) 90 http://www.medsci.org Int J Med Sci 2009, 314 Table Schedule of observations ... outcome The investigator assessed the adverse events and decided causality Classifications were as per the Coding Symbol Thesaurus of Adverse Reaction Terms (COSTART) U .S Food and Drug Administration ... groups were made at each visit using analysis of variance, using the baseline visit as a covariate SAS version 9.1 has been used to perform the statistical analysis Probability values less than...
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Báo cáo y học: " Vacuum-assisted closure in the treatment of early hip joint infection"
Ngày tải lên :
26/10/2012, 09:53
... debrided the skin parts of the tubes exit holes In cases with a macroscopically not clean operative situs, the sponges were only exchanged and tissue samples as well as parts of the removed V.A.C sponges ... on systemic haemodynamics, the surrounding tissue is decompressed and local microcirculation is re-established The increase of the oxygen gradient facilitates the transportation of toxins and inhibitors ... endoprosthesis involving the local tissue and causing an immune reaction [15] The most common problem hereby is the draining sinus, prolongating and preventing wound healing The pathophysiological...
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Báo cáo y học: " Two-stage procedure in the treatment of late chronic hip infections spacer"
Ngày tải lên :
26/10/2012, 09:53
... Antibiotic therapy tailored to the sensitivities of intraoperative cultures is continued for to weeks The decision to proceed with insertion of a new prosthesis is determined if the culture of a hip aspirate ... whilst preventing debris from accumulating in the potential joint space and decreasing the risk of soft-tissue contractures [18] Recent studies [19] suggest that the ALC may remove the need for systemic ... Various designs of articulating spacers have also been used including re-implantation of the excised prosthetic components after intraoperative sterilisation and specially designed reusable silicone...
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Báo cáo y học: "Complications after spacer implantation in the treatment of hip joint infections"
Ngày tải lên :
26/10/2012, 09:53
... properties of commercially available hip spacers containing a substantial stainless steel central core with experimental spacers containing Steinmann pins, intramedullary nails with two lag screws and ... joint infections Primary surgery primary THA bacterial coxitis aseptic cup loosening osteosynthesis for femoral neck fracture aseptic stem loosening dual head prosthesis osteosynthesis for intertrochanteric ... study and the limited possibility of interpreting these findings and their causes, this rate indicates that these patients are prone to have some kind of complication Orthopedic surgeons should...
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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
Ngày tải lên :
14/02/2014, 22:20
... how the brain senses and responds to nutrients, suitable targets for intervention in the nervous system–metabolism axis are still lacking Metabolic sensing Endocrine signals from the pancreas, ... from in silico sequences as a highly homologous member of the CPT1 class of enzymes and was shown to bind malonyl-CoA [47] Interestingly, its tissue distribution was restricted to the brain Being ... brain, suggesting that they are functionally distinct Although Signaling mediators in the treatment of obesity CPT1c is highly expressed in the hypothalamus, it is ubiquitously expressed in neurons...
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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
Ngày tải lên :
06/03/2014, 01:20
... is shown in Fig Excess calorie intake induces expression of RMI1 and E2Fs in adipocytes, and these changes in expression are expected to increase a positive interaction between the molecules The ... adipocytederived cell lines Intriguingly, both mRNA levels of E2F5 and E2F8 increased on treatment with glucose, as seen with RMI1, and siRNA knockdown of these genes suppressed RMI1 expression In addition, ... cyclin-dependent kinase inhibitors are important in the regulation of adipocyte number The S- phase kinase -associated protein (Skp)1–CullinF-box protein (SCF) ubiquitin ligase (E3) complex targets cyclin-dependent...
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Role of Corticosteroids in the Treatment of Tuberculosis: An Evidence-based Update potx
Ngày tải lên :
06/03/2014, 04:20
... effusion In this trial, use of corticosteroids was associated with faster clinical as well as radiological improvement However, it was also associated with a significantly increased risk of Kaposi s ... treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society ... subset of patients in this study.36 It was found that use of corticosteroids possibly reduced the risk of developing hydrocephalus and vasculitic infarcts; however, these findings were not statistically...
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Managing Drug Interactions in the Treatment of HIV-Related Tuberculosis docx
Ngày tải lên :
06/03/2014, 04:20
... rapidly-progressive HIV disease, so there are pressing reasons to assure potent treatment for both tuberculosis and AIDS In addition to the complexities raised by the drug interactions discussed above, ... several classes of drug transporting and drug metabolizing enzymes With increased synthesis, there is increased total activity of the enzyme (or enzyme system), thereby decreasing the serum half-life ... rifabutin being much less active Rifampin also upregulates the synthesis of cytosolic drug-metabolizing enzymes, including glucuronosyl transferase, an enzyme involved in the metabolism of zidovudine...
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Báo cáo khóa học: Characterization of novel structural features in the lipopolysaccharide of nondisease associated nontypeable Haemophilus influenzae pptx
Ngày tải lên :
16/03/2014, 16:20
... d strains [7,8] Gene functions have been identified in those strains that are responsible for most of the steps in the biosynthesis of the oligosaccharide portions of the LPS molecules The inner ... Hex3 LPS glycoform of NTHi strains 11 and 16 Discussion As part of our ongoing studies on the role of H in uenzae LPS in disease pathogenesis, we have undertaken a systematic analysis of LPS from ... feature on surface structures of pathogens residing in the human respiratory tract, including H in uenzae Expression of PCho has been associated with persistence of H in uenzae in the respiratory...
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Advances in the Treatment of Ischemic Stroke Edited by Maurizio Balestrino docx
Ngày tải lên :
23/03/2014, 17:20
... concentrations, as well as extracellular K+ Besides this biochemical response, within minutes after the onset of ischemia, there is an increase in gene expression Cells respond to stress by adjusting the ... normothermic rats and hypothermia blocked this decrease Even hypothermia blocks PKC cleavage, inhibition of caspase-3 assays showed that this caspase is not involved in this process, suggesting the ... RNA-binding domain proteins (CS-RBD) The “cold-inducible RNA-binding protein” (CIRP) is one of these proteins, and has been involved in protection as the result of hypothermia treatment in in vitro...
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gene therapy in the treatment of cancer
Ngày tải lên :
10/04/2014, 22:11
... Augmentation of Tumor Suppressor Genes Tumor suppressor genes are a genetically distinct class of genes involved in suppressing abnormal growth Loss of function of tumor suppressor proteins results in ... three steps need to be fulfilled prior to the use of antisense molecules The first is the establishment of the relevance of the genetic basis of carcinogenesis Second is the determination of the specific ... overexpressed in certain esophagus squamous cell carcinomas as well as other head, neck, bladder, and breast cancers Other functions for the cyclins exist as well The cyclin A gene is the site of integration...
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Evidence based Psychological Interventions in the Treatment of Mental Disorders A Literature Review
Ngày tải lên :
02/06/2014, 09:39
... NS NS NS NS NS NS NS NS NS NS NS NS NS NS Body dysmorphic NS NS NS NS NS NS NS NS NS NS NS NS NS NS Hypochondriasis NS NS NS NS NS NS NS NS NS NS NS NS NS NS Somatisation NS NS NS NS NS NS NS NS NS NS NS NS NS NS ... Eating disorders Anorexia nervosa IE IE IE Level I IE IE IE IE IE IE IE IE IE IE Substance use disorders Posttraumatic stress 20 NS NS NS NS NS NS NS NS NS NS NS NS NS NS Obsessive compulsive ... factors to clinical outcomes is provided A criticism of the use of the RCT as a necessary measure of the success of an intervention has been that in the real world the treatment setting is never as...
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