... specific labelling of ACh inthe pools after infiltration of labelled choline into the cerebral cortex (Chakrin and Whittaker, 1969) constitutes proof that the pools exist in vivo The binding of ACh ... between the level of ACh and the level of ChAc in different parts ofthenervoussystem (Silver, 1967), indicating that this enzyme governs the level of ACh The localization of ChAc is therefore ... supply of choline, and hence the choline for ACh-synthesis, in a lipid-bound form from the blood In some preliminary studies, the uptake of [Me-’4C]choline into the subcellular fractions of brain...
... selectivity ofthe palytoxin-induced pore Assuming that palytoxin might induce cation-permeable pores inthe apical membrane, the Isc evoked by the toxin should consist of an in ux of Na+, the prevalent ... we were interested in investigating the interactions ofthe toxin with the H+/K+-ATPase from rat colon The experiments were carried out in an Ussing chamber, which, compared to the single-cell ... paradigm, has the advantage of allowing one to asses at any time ofthe measurement either the apical or the basolateral surfaces ofthe epithelial cell membrane Administration of palytoxin on the apical...
... limited number of cytokines that inhibit the adhesiveness, growth and migration of cancer cells The most intriguing finding ofthe present study was that the function of MDA-7 in prostate cancer ... which resulted in complete death ofthe cells over the electrode The migration of healthy cells from the edge ofthe wounding to the wounding space was tracked Similar to thechanges seen with ... is linked to the invasiveness of prostate cancer cells [12] and participates inthe regulation ofthe interactions between prostate cancer cells and endothelial cells, the later involving the...
... limited number of cytokines that inhibit the adhesiveness, growth and migration of cancer cells The most intriguing finding ofthe present study was that the function of MDA-7 in prostate cancer ... which resulted in complete death ofthe cells over the electrode The migration of healthy cells from the edge ofthe wounding to the wounding space was tracked Similar to thechanges seen with ... is linked to the invasiveness of prostate cancer cells [12] and participates inthe regulation ofthe interactions between prostate cancer cells and endothelial cells, the later involving the...
... anti-inflammatory action of statins in RA The combined effects of DAF, at the level of C3 and C5 convertases, and of CD59 inhibiting the terminal attack complex has the potential to exert antiinflammatory ... respectively Furthermore, the failure of squalene to influence the response suggested that the mechanism underlying the actions ofthe statins was cholesterol independent Although the effect of statins on ... complement-mediated injury [18] DAF and MCP act at the level ofthe C3 convertase In contrast, CD59 inhibits the terminal pathway of complement activation, preventing the incorporation of C9 into the MAC...
... during oxidation Taurine-containing cells are present inthe myenteric plexus and submucosal plexus ofthe enteric nervoussysteminthe stomach Taurinergic neurons inthe muscle layer ofthe ... indicated by CSAD- and taurine-positive cells We found the presence of taurine-containing cells and taurine-induced acid secretion inthe stomach Inthe body ofthe stomach, taurine-immunoreactive cells ... processes inthe body (C), (D) A higher magnification ofthe area in (A) showing taurine-positive processes inthe antrum (E) A higher magnification ofthe area in (B) showing taurinepositive...
... explaining the purpose ofthe study to the prospective respondent General 33 instructions on completing the questionnaire and the importance of completing all questions were included The covering ... organization considering the costs of leaving In continuance commitment, the employees consider the disadvantages of leaving the organization and avoid quitting Continuance commitment also includes factors ... object to another, it is a measure ofthe 19 employees‟ willingness to remain with a firm inthe future It often reflects the employees‟ belief inthe mission and goals ofthe firm, willingness to...
... and the area ofthe residence Confidence intervals (CIs) were used in this study, as in clinical trials,7–10 to evaluate the equivalence ofthe two case-control studies in assessing the risk of ... prevalence of smoking between male living spouses of women who died of any cause and those spouses of women who died of some other causes other than smoking related causes The prevalence of smoking ... uncertain ofthe age when smoking began A validity study in Shanghai was conducted where the surviving spouse was the informant and both husband and wife had reported their smoking habits in the...
... Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Spring Rice – 2009 ( Quinal/ha) Number of paricals/m2 Number of grain/pan 1A 1B 12 LS DO5 % of umfiiied ... DO5 Number of grain/pan % of umfiiied grain 1000 grain weight(g) Grain yield Tab 6: Effect of KNO3 Spraying on rice yield on degraded Soie in Bac Giang 2009 ( Quinal/ha) Treat Spring Rice Summer ... umfiiied grain 1000 grain weight(g) Grain yield Tab 5: Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Summer rice – 2009 ( Quinal/ha) Number of paricals/m2...
... difficulty in understanding these concepts, which may have resulted in inconsistent responses We found inconsistencies in 12.2% ofthe sample, indicating the difficulties in communicating the information ... influence in their life Nine point seven percent ofthe participants were classified into the group with "high religiosity" There were no Muslim, Hindu or Buddhist participants The majority of ... among the study sites, but the data from the pilot project were not The following is an outline ofthe questionnaire: the first page was an informed consent form to participate inthe study The...
... chromium was located inthe middle ofthe specimen (Fig 4a) The Cr(VI) profile for kaolin as shown in Fig 5a indicates that the majority ofthe chromium was present inthe form of Cr(VI) and this ... inthe glacial till As a result of this, the electro-osmotic flow in contaminated kaolin is higher than that observed inthe contaminated glacial till The potable water initially introduced into ... velocity of 0.013 cmyh for kaolin and 0.03 cmyh for glacial till Thus, the electro-osmotic flow is slightly influenced by the soil type and the presence ofthe contaminants, including the form of chromium...
... chromium was located inthe middle ofthe specimen (Fig 4a) The Cr(VI) profile for kaolin as shown in Fig 5a indicates that the majority ofthe chromium was present inthe form of Cr(VI) and this ... inthe glacial till As a result of this, the electro-osmotic flow in contaminated kaolin is higher than that observed inthe contaminated glacial till The potable water initially introduced into ... velocity of 0.013 cmyh for kaolin and 0.03 cmyh for glacial till Thus, the electro-osmotic flow is slightly influenced by the soil type and the presence ofthe contaminants, including the form of chromium...
... chromium was located inthe middle ofthe specimen (Fig 4a) The Cr(VI) profile for kaolin as shown in Fig 5a indicates that the majority ofthe chromium was present inthe form of Cr(VI) and this ... inthe glacial till As a result of this, the electro-osmotic flow in contaminated kaolin is higher than that observed inthe contaminated glacial till The potable water initially introduced into ... velocity of 0.013 cmyh for kaolin and 0.03 cmyh for glacial till Thus, the electro-osmotic flow is slightly influenced by the soil type and the presence ofthe contaminants, including the form of chromium...
... inthe baseline health status reached minimal clinical significance, and may have influenced thechangesin health status However, except for the baseline score ofthe Symptoms inthe SGRQ, the ... total score ofthe CRQ Following the baseline scores, the frequency of exacerbations significantly accounted for thechangesinthe Mastery ofthe CRQ (R2 = 0.03) and the Symptoms ofthe SGRQ (R2 ... baseline were observed in two domains (Dyspnea and Emotion), the total scores ofthe CRQ and inthe Activity scores ofthe SGRQ In subjects with exacerbations, statistically significant declines in...
... inthe baseline health status reached minimal clinical significance, and may have influenced thechangesin health status However, except for the baseline score ofthe Symptoms inthe SGRQ, the ... total score ofthe CRQ Following the baseline scores, the frequency of exacerbations significantly accounted for thechangesinthe Mastery ofthe CRQ (R2 = 0.03) and the Symptoms ofthe SGRQ (R2 ... baseline were observed in two domains (Dyspnea and Emotion), the total scores ofthe CRQ and inthe Activity scores ofthe SGRQ In subjects with exacerbations, statistically significant declines in...
... mg/kg/day of acrylamide showed histopathological changesinthe seminiferous tubules (Fig 5B) There were thickening and multiple layering ofthe tubular endothelium, degeneration of germ cells, and the ... formation of many multinucleated giant cells (arrow heads) in seminiferous tubules H & E stain, ×50 and multiple layering ofthe tubular endothelium, degeneration of germ cells, and the formation of ... mM of acrylamide significantly increased the frequencies of chromosomal aberration inthe presence or absence of S9 mixture Moreover, the cells treated with 10 or 50 mM of acrylamide further increased...
... targets of anti-TNF-α activity in RA, and may provide an insight into a new and interesting mechanism of action of anti-TNF-α mAbs inthe control of inflammatory arthritis Competing interests The ... neutrophils were mixed in ml polystyrene vials with × 10-5 mol/l lucigenin in a final volume of 700 µl The vials were placed inthe Luminometer 1251 (LKB Wallace, Turku, Finland) inthe dark and allowed ... phagocytic cells and the involvement of these cells inthe host defence against infections suggest that impairment in phagocytic cell activity may heighten the risk for infection during TNF-α neutralization...
... peptide (AP9) on the invasive ability ofthe co-culture cells (a) The haematoxylin and eosin staining results ofthe cells lower surface filters show that the cells had invaded through the filter and ... showed positive expression of TIMP-1 inthe lining and the sublining layers The expression of CD147 correlated significantly with that of MMP-1 (p < 0.05), but the expression of CD147 and MMP-1 did ... metalloproteinase-1 (RA MMP-1), tissue inhibitor of metalloproteinases-1 (RA TIMP-1) and blank contrast (RA blank) inthe lining and sublining layers in RA synovium (× 400) The bottom two images show the...
... the role of CYC inthe care of these patients In our meta-analysis, two ofthe three greatest mean differences ofthe FVC after 12 months of therapy were achieved in observational studies using ... difference inthe meta-analysis The overall pooled analysis included the mean changesofthe FVC and the DLCO after 12 months of therapy obtained from the observational studies and from the CYC ... within the range of those reported inthe literature altered the results Adverse events We evaluated the relative risk of having adverse events inthe CYC group compared with the control groups in...
... flow into a collecting circuit filled with heparinized saline (4 U/ml of saline) positioned 54 cm above the rat The temperature ofthe blood inthe syringe was maintained at 37- 37.5°C The aortic ... recovery of hind limb function The placing/stepping reflex (SPR) was assessed by dragging the dorsum ofthe hind paw along the edge of a surface This normally evokes a coordinating lifting and placing ... responses ofthe spinal cord in IRI but also its clinical neurological impacts [14] Interruption of aortic blood flow in IRI may not only induce spinal cord injury, but also induce injury ofthe heart,...