cellular and regulatory mechanisms of the anabolic actions of parathyroid hormone
Báo cáo y học: " Cellular and molecular mechanisms of cigarette smoke-induced lung damage and prevention by vitamin c" ppsx
... activation of caspase and cleavage of PARP There was a rise in the level of the proapoptotic Bax protein, but no rise in the level of the antiapoptotic Bcl-2, resulting in an increase of the Bax/ ... made in the trachea and one end of a tube (Tygon tube 020 ID 060 OD 10, Small Parts, Inc USA) was inserted into the trachea and the other end drawn beneath the skin to open up at the back of the ... water through the side tube for sec Thereafter, the vacuum was turned off and the guinea pig was further exposed to the accumulated smoke for another 40 sec The total duration of exposure to...
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MORPHOGENESIS THE CELLULAR AND MOLECULAR PROCESSES OF DEVELOPMENTAL ANATOMY pptx
... biologists and wish became the father of thought and the grandfather of observation: they claimed to see small but fully formed organisms in the sperm of men, horses, cocks and other animals and also ... distinct tissues come together, and here we will examine the generation of the neural tube in the newt and the formation of the ducted submandibular glands of the mouse The latter example in particular ... development, the position of epithelial folding, the direction of spindle orientation and hence the direction of cell growth, the amount of sac contraction, and the symmetry of epithelial drying...
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Báo cáo khoa học: Cellular and molecular action of the mitogenic protein-deamidating toxin from Pasteurella multocida pptx
... intoxication of PMT Little is known about the cellular uptake mechanisms of PMT Bacterial protein toxins are known to utilize a number of different entry routes, and the nature of the receptor often ... In this review, we focus on PMT and our current understanding of the structure–function, mechanism of action and cellular consequences of this newest member of the G-protein-deamidating dermonecrotic ... Although the precise localization of the domains responsible for receptor binding and translocation activity remains unclear, these domains are located in the N-terminus of each of these toxins and...
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Báo cáo khoa học: Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry potx
... process of penetration begins The latter, depending on the host cell type and the mode of entry [4,5], may require fusion of the virion envelope with the plasma membrane or with the membrane of an ... for the release of the viral nucleocapsid proximal to the nucleus the inoculation site; therefore, sores are most commonly found on the mouth or genital areas Medical professionals and others ... most of the tegument proteins are required for activation and modulation of viral gene expression and shut-off of host protein synthesis, some may participate in dynein-propelled transport of the...
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A review of the chemical and physical mechanisms of the storage stability of fast pyrolysis bio oils
... during pyrolysis • The extent of vapor dilution in the reactor • The time and temperature history of the vapors in the reactor • The time and temperature history of the vapors in the heated transfer ... volume” of the solute, solubility is predicted This is satisfied if the distance from the center of the solvent sphere to the center of the solute sphere (Rij) is smaller than the radius of the solute ... catalyze the polymerization of olefins and the addition of mercaptans to olefins The organic acids and the elements commonly found in the char can act as catalysts for many of these reactions...
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Báo cáo y học: "Analysis of the contribution of cellular and viral RNA to the packaging of APOBEC3G into HIV-1 virions" docx
... conceived the study, was leading the execution of the experiments, and participated in the writing of the manuscript K.S coordinated and supervised the study and was involved in the writing of the ... independent of genomic RNA [28,32] Furthermore, the efficiency of encapsidation of most of the cellular RNAs seems to reflect their cellular abundance [28,32,33] One of the first cellular RNAs ... amounts of PCR products indicative of the presence of similar levels of these cellular RNAs in all three particle preparations These results suggest that packaging of these RNAs was independent of the...
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Investigations on the cellular and neuroprotective functions of nogo AReticulon 4a
... and exons and encoding the C-terminus with the ER retention signal and the 3‟ UTR An illustration of the domain structures of Nogo-A, -B and -C is shown in Fig 1.2A Nogo-A is the longest of the ... structure and topology of Nogo (A) A schematic diagram of the three major splice isoforms of Nogo (Nogo-A, -B and -C) and their domain structures, with their aa sizes indicated Nogo-A and -B share the ... N-terminus of Nogo facing extracellularly came from the study of the topology of Nogo-B on the surface of endothelial cells (Acevedo et al., 2004) Nogo-A has also been postulated to adopt other topologies...
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Assessing the Legal and Regulatory Context of a Corridor
... reflects the willingness and commitment of the parties concerned by the development of the corridor and endorsed by them, including a memorandum of understanding, a convention, a treaty, or other ... July 1996, the Council of heads of states of the members of the Economic Community of Central African States (UDEAC) agreed on the legal framework of road transport of general cargo in the subregion ... March 2007 by Burundi, the Democratic Republic of Congo, Kenya, Rwanda, and Uganda, this agreement extends the mandate and scope of the 1985 agreement, renews the protocols, and develops new ones...
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Tài liệu Báo cáo khoa học: Active and regulatory sites of cytosolic 5¢-nucleotidase doc
... disappearance of the heavier inactive peak Furthermore, FPLC analysis of the recombinant wild-type cN-II showed the presence of the tetrameric active form irrespective of the presence of effectors ... determine the value of K50 for these compounds Under these experimental conditions, the accumulation of radiolabelled inosine (nucleotidase activity) represents the sum of the phosphatase and the phosphotransferase ... considered as caused either by an alteration of the Km value for one of the two substrates or by a variation of the kcat value for one of the two activities When required, the rate of phosphate formation...
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báo cáo khoa học: " XAF1 expression and regulatory effects of somatostatin on XAF1 in prostate cancer cells" docx
... regulating the activities of phosphotyrosine phosphatases [23] In the current study, we examined XAF1 mRNA and protein expression in four cell lines, and determined regulatory effects of somatostatin and ... Up-regulation of XAF1 mRNA and protein by somatostatin and Octreotide in prostate cancer cell lines To examine the regulatory effects of somatostatin and Octreotide on XAF1 mRNA and protein expression, ... Vapreotide, Seglitide and so on, are available for the treatment of several kinds of disorders Octreotide was the first developed analogue and is widely used for symptomatic treatment of hormone secreting...
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báo cáo khoa học: " Transcriptional regulatory programs underlying barley germination and regulatory functions of Gibberellin and abscisic acid" doc
... available data; however, the USDA neither guarantees nor warrants the standard of the product, and the use of the name by USDA implies no approval of the product to the exclusion of others that may also ... under-represented in the Photosynthesis pathways Thus, the expression of the genes in the photosynthesis pathways changed little in the other germination phases, and the photosynthesis pathways were ... compared and displayed as Venn diagrams 10A compares GA and germination; 10B compares ABA and germination; and 10C shows the comparison of GA, ABA and germination The number of probe-sets and their...
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Báo cáo y học: " Central and peripheral mechanisms of narcotic antitussives: codeine-sensitive and -resistant coughs" ppt
... the interstitial and ventrolateral subdivision of the nucleus tractus solitarius (NTS), the reticular formation (the medial part of the lateral tegmental field, and the internal division of the ... the lower airway [30,31] and its stimulation causes cough-like response [32,33] The NTS is more heavily labeled by the µ-ligand than by the κ-ligand in guinea pigs and cats [29,34] Further, the ... very high doses Further studies are needed to clarify the pharmacology and mechanisms of antitussive effects of opiates, and to elucidate mechanisms of opiate-resistant coughs Furthermore, it is...
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Báo cáo y học: "Protective effects and potential mechanisms of Pien Tze Huang on cerebral chronic ischemia and hypertensive stroke" docx
... to compare individual pairs of groups The stroke scores of the SHRsp groups were analyzed with Chisquare test and the means of the time of survival after stroke of the SHRsp groups were analyzed ... (China) and was supported by the proposal of the Second Development of Pien Tze Huang of the National Ministry of Science and Technology Author details School of Biomedical Sciences, Faculty of Medicine, ... vocabulary for describing the roles of genes and their products with respect to biological process, molecular function and cellular component of the genes’ products In the analysis, the background list...
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Reliability and aging mechanisms of all solid state thin film lithium ion microbatteries
... combination of various SPM techniques Finally, Chapter summarizes the contributions of this thesis and makes suggestions for future research to further understand the aging mechanisms of thin film ... behavior of thin film electrodes are still blank The main objective of this study was to investigate the degradation of interfacial reliability of thin film electrodes, and to analyze the aging mechanisms ... anode and cathode to investigate the mechanical failure in Chapters and 6, respectively Chapter discusses the effects of charge/discharge rate and depth of discharge (DOD) on the degradation of...
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Response and failure mechanisms of structural member under high velocity impact
... Swaddiwudhipong and Dr Liu Zishun for their constant encouragement and guidance during the course of my study and the preparation of this thesis Their guidance and advice have contributed immeasurably to the ... setup and specimen preparation, and the inability to use for others materials, geometries and impact velocities outside the test range The analytical model is based on the development and use of the ... Application of the SFM for high velocity impact simulation of steel and aluminum alloy targets where the SPH method is used at the region of large deformation and damage, and the FEM elsewhere Study of...
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Cellular and molecular control of skeleton formation in fish insights from osteoblast ablation and functional characterization of lrp5 and SOst
... (Renn and Winkler, 2009) osx transgenic expression was observed in advance of mineralization of the neural and hemal arches and at the edges but not the core of the chordal centrum Therefore, whether ... him and his family all the best for the future Thanks to all my dear lab mates for the support and the help and the wonderful atmosphere we had throughout the years I wish them good luck and ... such as cleithrum, operculum and pharyngeal teeth in the head, the fin rays of the caudal fin and in neural and hemal arches as well as the edges of the centra in the axial skeleton (Fig 3.C-E)...
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Regulatory mechanisms defining the blastocyst cell lineages
... embryonic part of the blastocyst and the other becomes the abembryonic part It also has been argued that the orientation of the first cleavage, implied to be marked by the position of the second ... generated independently of early cell cleavage but is related with the shape of the zona pellucida And the rotation of the embryo within the zona pellucida may help to explain the lack of correlation ... colocalized and their expression level appears to be random within the individual cells of the morula (Dietrich and Hiiragi, 2007; Plusa et al., 2008) These findings raise the possibility of a stochastic...
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Báo cáo y học: " Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: Implications for transformation" pps
... Fischer E, et al.: Parathyroid hormone- related protein and its receptors: nuclear functions and roles in the renal and cardiovascular systems, the placental trophoblasts and the pancreatic islets ... figure 5, the expression of tax did not correlate temporally with the expression of PTHrP HTLV-1 and HTLV-1 Rex up-regulated PTHrP expression In order to investigate the direct effect of the HTLV-1 ... The differences between the levels of PTHrP mRNA and protein expression were likely due to differences in translation efficiency, processing of the mature protein, and/ or its secretion from the...
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báo cáo hóa học: " Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE" pptx
... clinical disease Taken together, the results of the present study and from previous ones on the role of CCR1 and its ligand CCL3 in the pathogenesis of MS [39,40,42] and EAE [22,44,46], have provided ... crucial for the understanding of therapeutic modulation and the validation of CCR1, CCR2 and CCR5 as feasible targets for therapeutic intervention in MS Background Multiple sclerosis (MS) is the most ... from Finland, suggesting that the lack of CCR5 does not protect from MS, but rather it may predispose to the chronic course of the disease [69] This would further imply that in view of the redundancy...
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Báo cáo y học: "Cellular mechanisms underlying the effects of an early experience on cognitive abilities and affective states." ppt
... NON HANDLED NON HANDLED HANDLED B HANDLED NUMBER OF POSITIVE CELLS 35 30 25 20 15 10 CA4 Figure handling on BDNF immunoreactivity in the CA4 region of the hippocampus Effect of3 Effect of handling ... 200 150 NON-HANDLED 100 HANDLED 50 5-HT1A Figure Effects of handling on the density of 5-HT1A receptors in the hippocampus Effects of handling on the density of 5-HT1A receptors in the hippocampus ... R OF POSIT VE IVE CE L L S 45 NO N HANDLED HANDLED 40 35 30 25 20 15 10 C A2 C A2 Figure Effects of handling on MR and GR immunoreactivity in the CA2 region of the hippocampus Effects of handling...
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