cd2ap rabip4 and rabip4prime analysis of interaction with rab4a and regulation of endosomes morphology

Báo cáo sinh học: "A functional genomic analysis of cell morphology using RNA interference" pptx

Báo cáo sinh học: "A functional genomic analysis of cell morphology using RNA interference" pptx

Ngày tải lên : 06/08/2014, 18:20
... altered DNA morphology, indicative of growth in the absence of division A second group (Profile II) was defined by an increase in the frequency of cells with a microtubule spindle, indicative of a defect ... based on the shape and length of the cell edge and an estimate of the spreading area); (d) processes, spiky or stretchy (a description of the cell edge, in combination with F-actin and microtubule ... appearance of phenotypes and/ or depletion of the targeted gene products When Volume 2, Issue 4, Article 27 Kiger et al 27.3 Selection and generation of gene-specific dsRNAs Screens of RNAi morphological...
  • 15
  • 261
  • 0
báo cáo khoa học: " A radiographic analysis of tooth morphology following the use of a novel cyclical force device in orthodontics Chung H Kau" pps

báo cáo khoa học: " A radiographic analysis of tooth morphology following the use of a novel cyclical force device in orthodontics Chung H Kau" pps

Ngày tải lên : 11/08/2014, 20:21
... [8] The “gold standard” to measure root resorption is to sacrifice the tooth and surrounding alveolar bone and to histologically analyze the morphology However, this type of analysis is not possible ... It has a scan time of 14 s and captures the maxilla-mandibular region in a 210° rotation within a radiation-detector configuration The field of view is a spherical volume of 15 cm The voxel size ... start of treatment (T1) and again after six months of treatment (T2) Measurements of all teeth present were made from the mesial buccal roots of the first molar on one side of the dental arch to...
  • 5
  • 352
  • 0
Báo cáo khoa học: Site-directed mutagenesis and footprinting analysis of the interaction of the sunflower KNOX protein HAKN1 with DNA ppt

Báo cáo khoa học: Site-directed mutagenesis and footprinting analysis of the interaction of the sunflower KNOX protein HAKN1 with DNA ppt

Ngày tải lên : 23/03/2014, 13:20
... 4B) This agrees with the presence of a larger residue that makes stable contacts with this region of DNA The interaction of mutants at position 50, and particularly of I50K–HAKN1 with DNA, provides ... HAKN1–DNA interaction Based on the analysis of the binding of wild-type and mutant HAKN1 homeodomains to different DNA target sites, we propose a model for the interaction of HAKN1 with DNA A set of ... were separated and analysed The left and right panels in (A) and (B) represent the top and bottom strands of the binding site, respectively A portion of the same fragment digested with defined restriction...
  • 13
  • 558
  • 0
Báo cáo y học: "Segment-orientated analysis of two-dimensional strain and strain rate as assessed by velocity vector imaging in patients with acute myocardial infarction"

Báo cáo y học: "Segment-orientated analysis of two-dimensional strain and strain rate as assessed by velocity vector imaging in patients with acute myocardial infarction"

Ngày tải lên : 25/10/2012, 11:15
... cut-off value of –10.34% resulted in a sensitivity of 54 % and specificity of 59 % (see Table 6) The intra- and inter-observer variation of our data is congruent with the data of Jarnert et al and ... segments with a sensitivity of 80% and a specificity of 70% (AUC 0.8) with a cut-off value of less than 1.95 cm/s Poor agreement between VVI and TDI measurements have been previously demonstrated, and ... segments with LE ≥ 51% and LE 1-50% 15 By using the previously proposed cut-off value 15 for strain of –6.5 % a sensitivity of 23 % and specificity of 87 % was calculated for the detection of infarcted...
  • 8
  • 683
  • 0
Comparing the cultural and linguistic analysis of the English word “meal” and words relating to it in contrast with Vietnamese equivalents.

Comparing the cultural and linguistic analysis of the English word “meal” and words relating to it in contrast with Vietnamese equivalents.

Ngày tải lên : 15/04/2013, 15:11
... morning and a nice cup of tea at night And at half past seven, their idea of heaven is a nice cup of tea They like a nice cup of tea with their dinner and a nice cup of tea with their tea, and before ... conditional breakfast They often have cereal or porridge, egg and bacon followed by toast and marmalade and coffee and tea or they may just have a toast and marmalade and coffee and tea *Elevenses - ... Definition of word meal - Field of word meal in English and in Vietnamese equivalents - Cultural and linguistic analysis of the English word meal Chapter III Cultural and linguistic analysis of Vietnamese...
  • 54
  • 1K
  • 1
River Water Quality Analysis of Hadano Basin and its Relationship with Nonpoint Sources of Pollution

River Water Quality Analysis of Hadano Basin and its Relationship with Nonpoint Sources of Pollution

Ngày tải lên : 05/09/2013, 10:17
... of water and natural outflow of ground water (spring) are the salient features - 142 - Journal of Water and Environment Technology, Vol 9, No.2, 2011 of this city This study on the analysis of ... Journal of Water and Environment Technology, Vol 9, No.2, 2011 Land use data of each drainage basin was extracted in GIS and the area of each land use type was calculated (Fig 6).Building data with ... Overlay of sewered area Overlay of sewered area and households Separation of unsewered households Fig - Separation of unsewered households of Minasebashi basin of Mizunashi River - 147 - Journal of...
  • 28
  • 593
  • 0
A contrastive analysis of idioms denoting humans with dispraising implications in english and vietnamese

A contrastive analysis of idioms denoting humans with dispraising implications in english and vietnamese

Ngày tải lên : 26/11/2013, 13:31
... learners of a foreign language in general and semantic features of English idioms denoting humans with dispraising implication (IDHDIE) and Vietnamese ones (IDHDIV) 1.2.2 Objectives of the Research With ... stylistic and semantic features of IDHDIE and IDHDIV - Finding out the similarities and differences between IDHDIE and IDHDIV - Making some suggestions for teaching, learning and Vietnamese learners of ... kinds of idioms denoting humans This study concentrates on major 1.2 AIMS AND OBJECTIVES syntactic, stylistic and semantic features of IDHDIE and IDHDIV From the reasons above and in high hope of...
  • 14
  • 1.9K
  • 4
Tài liệu an analySiS of euro area Sovereign CDS anD their relation With government bonds docx

Tài liệu an analySiS of euro area Sovereign CDS anD their relation With government bonds docx

Ngày tải lên : 16/02/2014, 02:20
... Lead-lag analysis of bond spreads and CDS 3.5 Regression analysis of the basis 3.6 Further results for the regression analysis of the basis 15 15 17 18 20 22 Conclusions 26 Figures and tables ... of Germany, France, Netherlands, Belgium and Austria is positively related to the amount outstanding of bonds divided by GDP (coefficient of 51.93) Our analysis cannot explain the direction of ... snapshots relative to the volume of total bonds outstanding For Greece, the net open CDS amount to around 3% of their outstanding sovereign debt and for Portugal and Ireland around 7% This magnitude...
  • 49
  • 1.5K
  • 0
Tài liệu Báo cáo khoa học: Delineation of exoenzyme S residues that mediate the interaction with 14-3-3 and its biological activity ppt

Tài liệu Báo cáo khoa học: Delineation of exoenzyme S residues that mediate the interaction with 14-3-3 and its biological activity ppt

Ngày tải lên : 19/02/2014, 08:20
... Delineation of ExoS residues L Yasmin et al Fig Interaction of GST-ExoS variants with endogenous 14-3-3 proteins HeLa cells were harvested and lysates were subjected to ‘pulldown’ analysis with lg of ... filters with anti-Ras (D) and with anti-Erk (E) antibodies ogy, concomitant with a disruption of actin microfilaments, and ultimately cell death (compare Fig 4B with 4F), corroborating with earlier ... et al Delineation of ExoS residues Fig Morphological analysis of HeLa cells infected with variants of ExoS HeLa cells in the presence of 0.1% arabinose, were infected with: (B) and (F) YPIII (pMF384)...
  • 9
  • 525
  • 0
Tài liệu MECHANICAL PROPERTIES OF THE HEART AND ITS INTERACTION WITH THE VASCULAR SYSTEM ppt

Tài liệu MECHANICAL PROPERTIES OF THE HEART AND ITS INTERACTION WITH THE VASCULAR SYSTEM ppt

Ngày tải lên : 22/02/2014, 09:20
... understanding and will be the focus and repeating theme throughout the text A sound understanding of cardiac physiology begins with basic understanding of cardiac anatomy and of the physiology of ... composed of bundles of myosin strands with each strand having a tail, a hinge and a head region The tail regions bind to each other in the central portion of the filament and the Page of 23 strands ... of this manuscript is to provide a detailed understanding of the heart as a muscular pump and of the interaction between the heart and the vasculature The concepts of contractility, preload and...
  • 23
  • 578
  • 0
Báo cáo khoa học: Ion-binding properties of Calnuc, Ca2+ versus Mg2+ – Calnuc adopts additional and unusual Ca2+-binding sites upon interaction with G-protein pdf

Báo cáo khoa học: Ion-binding properties of Calnuc, Ca2+ versus Mg2+ – Calnuc adopts additional and unusual Ca2+-binding sites upon interaction with G-protein pdf

Ngày tải lên : 07/03/2014, 00:20
... off’ the dye (attenuating both the J-band and the c-band), indicating that the dye binds in the EF-hand motif Binding of Mg2+ caused a decrease only in the c-band, without disturbing the J-band ... relationship of Calnuc M Kanuru et al Although de Alba and Tjandra have reported the affinities (Kd of 47 and 40 lm) of Ca2+ for peptides comprising the EF-hands of Calnuc [42], there are no reports of ... expression of two isoforms of Calnuc Isoform of Calnuc in mammals evolved as a separate group, along with Calnuc from Gallus The phylogram thus shows a clear, distinct and early evolutionary pattern of...
  • 18
  • 333
  • 0
Báo cáo khoa học: Interaction analysis of the heterotrimer formed by the phosphatase 2A catalytic subunit, a4 and the mammalian ortholog of yeast Tip41 (TIPRL) ppt

Báo cáo khoa học: Interaction analysis of the heterotrimer formed by the phosphatase 2A catalytic subunit, a4 and the mammalian ortholog of yeast Tip41 (TIPRL) ppt

Ngày tải lên : 07/03/2014, 05:20
... Parallel purification of three catalytic subunits of the protein serine ⁄ threonine phosphatase 2A family (PP2A(C), PP4(C), and PP6(C)) and analysis of the interaction of PP2A(C) with a4 protein Protein ... identification of interaction- deficient mutants as determined by loss of the His3+ phenotype and loss of activation of the lacZ reporter gene Subsequently, clones showing loss of interaction were ... the interaction of TIPRL with the C-terminal region of the catalytic subunits of type 2A phosphatases TIPRL forms a heterotrimeric complex with PP2Ac and a4 and does not compete with a4 for PP2Ac...
  • 14
  • 419
  • 0
Báo cáo khoa học: Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p pptx

Báo cáo khoa học: Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p pptx

Ngày tải lên : 07/03/2014, 16:20
... Here we confirm and extend earlier studies of these AAA-peroxins and give a further detailed functional analysis of their cassette structure and interaction The interaction of Pex1p and Pex6p involves ... of Pex1p and Pex6p A B Fig Two-hybrid interaction of Pex1p and Pex6p harboring point mutations of the WalkerA and B motifs of their ATP-binding sites A schematic representation of the Pex1p and ... by overlapping PCR with primers KU473 and KU474 and digestion with XbaI and PstI After ligation with BamHI ⁄ XbaI and PstI ⁄ BamHI fragments of psk100 and subsequent digestion with BglI, it was...
  • 12
  • 584
  • 0
chronopotentiometric stripping analysis of gelatinase b, collagen and their interaction

chronopotentiometric stripping analysis of gelatinase b, collagen and their interaction

Ngày tải lên : 21/03/2014, 12:18
... Signals of collagen, MMP-9 and collagen after interaction with MMP-9 measured by AdTS CPSA (interaction time: 30 s) D) Height of CPSA peaks of collagen (0.5 or mg/mL) after interaction with MMP-9 ... does Collagen was dissolved with 9% HCl (m/m) and used in the following experiments 3.2 Collagen Modified HMDE 3.3 Interaction of MMP-9 with Collagen Preparation of standard collagen solutions ... observed Electroanalysis 2009, 21, No 3-5, 536 – 541 during the analysis of denatured protein p53 [35, 36], urease [37] and lactoferrin [38 – 40] Conclusions Study of protein-protein interactions...
  • 6
  • 451
  • 0
Báo cáo khoa học: Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor potx

Báo cáo khoa học: Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor potx

Ngày tải lên : 22/03/2014, 16:21
... g) and 20 °C RI - RATE complex RI - RNase A complex RI Fig Analysis of the stoichiometry of the RI–SGRSGRSG-RATE complex by native PAGE Lanes and 2: complex of RNase A (100 pmol) with RI (200 and ... stoichiometry of the complex between RI and RATEs, 100 or 200 pmol of RI was incubated either with 100 pmol of SGRSGRSG-RATE or with 100 pmol of RNase A at 25 °C for 15 in 15 lL of 0.1 m sodium ... Superimposition of the crystal structures of the RATEs with the linker sequences GPPG, SGSGSG, and SGRSGRSG Fig S2 Analysis of the stoichiometry of the RIÆSGRSGRSG-RATE complex by native PAGE Fig S3 Analysis...
  • 10
  • 535
  • 0
Báo cáo khoa học: Contribution of a central proline in model amphipathic a-helical peptides to self-association, interaction with phospholipids, and antimicrobial mode of action ppt

Báo cáo khoa học: Contribution of a central proline in model amphipathic a-helical peptides to self-association, interaction with phospholipids, and antimicrobial mode of action ppt

Ngày tải lên : 23/03/2014, 10:21
... electrostatic interactions, whereas the interaction of PFPs with membranes was most affected by hydrophobic interactions These properties may lead to the selectivity of PCPs and ⁄ or the nonselectivity of ... duplicate SPR analysis of interaction between peptides and phospholipid bilayers The interaction of the peptides with the phospholipid bilayers was analyzed by SPR using a BIACORE 2000 equipped with an ... role of a central Pro on the biological activity, peptide structure, and interaction with membranes One interesting finding of this study was that introduction of a Pro in the middle position of...
  • 15
  • 376
  • 0
BUSINESS AND Financial analysis OF BRITISH  PETROLEUM WITH COMPARISON TO SHELL PLC

BUSINESS AND Financial analysis OF BRITISH PETROLEUM WITH COMPARISON TO SHELL PLC

Ngày tải lên : 25/03/2014, 11:06
... comparisons of these two companies are taken for the development of the complete understanding and analysis of the topic under the research 36 Business and Financial Analysis of BP with comparison ... enlightening, explorative and elaborating to the issue of economic analysis and the business analysis 38 Business and Financial Analysis of BP with comparison to Shell PLC 3.5 2011 Method of Research For ... the financial and the business analysis of the company 46 Business and Financial Analysis of BP with comparison to Shell PLC 4.3 2011 Financial analysis of the British petroleum with comparison...
  • 84
  • 400
  • 1
Báo cáo khoa học: The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2 pot

Báo cáo khoa học: The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2 pot

Ngày tải lên : 30/03/2014, 01:20
... the one hand, and of the positive charge of the RS domain with the negatively charged ‘docking groove’ of SRPK1, on the other hand The RE-rich region of SAFB1 may interfere with any of these ... lanes and 1) These results confirm the direct interaction of SAFBs with the SRPK1 ⁄ 1a proteins and provide a direct link between the affinity of the SAFB–SRPK1 ⁄ 1a interaction and the extent of ... significance of enzyme–substrate contacts for catalysis This study highlights the importance of the interaction of a phosphoserine of the RS domain of the substrate with the catalytic region of the...
  • 16
  • 573
  • 0
Báo cáo khoa học: Cholesterol interaction with the related steroidogenic acute regulatory lipid-transfer (START) domains of StAR (STARD1) and MLN64 (STARD3) ppt

Báo cáo khoa học: Cholesterol interaction with the related steroidogenic acute regulatory lipid-transfer (START) domains of StAR (STARD1) and MLN64 (STARD3) ppt

Ngày tải lên : 30/03/2014, 04:20
... Fig Cholesterol labeling and chemical cleavage of STARD1START STARD1-START (20 lg of protein, filled circles and diamonds, and 60 lg of protein, open circles) was incubated with [3H]photocholesterol ... [3H]photocholesterol and fragments of less than  kDa Table Efficiency of labeling of the 6.2 kDa fragment with [3H]photocholesterol in STARD1-START Labeling was performed with [3H]photocholesterol (50 lM) and ... cholesterol-binding site of the START domains of STARD1 and STARD3? The crystal structure of human STARD3-START revealed an a ⁄ b-fold consisting of a nine-stranded twisted b-sheet and four a-helices...
  • 13
  • 404
  • 0
Báo cáo khoa học: Molecular analysis of the interaction between cardosin A and phospholipase Da Identification of RGD/KGE sequences as binding motifs for C2 domains pdf

Báo cáo khoa học: Molecular analysis of the interaction between cardosin A and phospholipase Da Identification of RGD/KGE sequences as binding motifs for C2 domains pdf

Ngày tải lên : 30/03/2014, 11:20
... presence of 0.2 mm Ca2+ with and without mm EGTA, respectively, gave identical results and therefore suggest that this interaction is calcium independent Interaction between cardosin A and PLDa ... superimposition of the 3D structures of kistrin [32] and cardosin A (Fig 8) The importance of both motifs and in particular their basic residues was further emphasized by the complete lack of interaction ... cells, the fundamental role of the RGD-mediated interaction between integrins and their ligands for the activation of essential signalling pathways in cell proliferation and growth has been well...
  • 13
  • 455
  • 0