... parallel The numbers at the right represent the pI values ofthe major bands in e and f, while the numbers at the left are the pI values of standard proteins The arrow at the right represents the ... lg) and f (1.5 and 3.0 lg) show the electrophoretic position of CLAP fractions e and f, respectively, after re-chromatography on Mono S (Fig 1B,C) The (0) at the bottom shows the absence of protease ... position of CL and CLAP, the catalytic and noncatalytic subunits, respectively, ofthe protease are shown on the right, while protein standards are shown on the left (B) Lanes labelled e (1.5 and...
... function to activate Notch only in the absence of p53, possibly due tothe interference of Notch activation by p53 The main aim of this study is to find out the causes for the up-regulation of p53 ... particularly what causes the up-regulation of p53 activity Hence, the aim of this study is to investigate what causes the up-regulation of p53 andto further characterize other developmental defects ... regulatory checkpoints The first regulatory event is the G1/S checkpoint, which defines the entry into the cycle in late G1; the G2/M checkpoint, where entry into mitosis is controlled; and the...
... specialization” and is commonly referred to as the relocation of parts ofthe production process from one country to another Most ofthe attention used to focus on fragmentation in the goods chain, ... Among the factors explaining the growth is the expansion of defence R&D andthe fast accumulation of IT skills by university graduates and graduates ofthe military technological units These countries ... matched tothe local environment While education and training policies were supportive ofthe automobile industry in general, they were never the main factor for attracting automobile investors in the...
... due to fluctuations of prices and costs, and was represented by additive error of 10% for the purpose of this study Its value can also be reduced by thedevelopmentof relevant economic and marketing ... climate are the main sources ofthe final error In addition, the low presence of some tree species in the source data set negatively influenced the accuracy ofthe results Theoretically, the standard ... pure, even-aged and full stocked forest stands, which is related tothe essence of basic models used as a source for the yield index computation There arises a question whether andto what extent...
... Figure The GSH/GSSG ratio ofthe prototype and expanded models The GSH/GSSG ratio ofthe prototype and expanded models The prototype model (A) andthe expanded model (B) Page of 11 (page number not ... hexokinase and pyruvate kinase, andthe maximum activity of these enzymes was allowed to change according tothe ratio of GSH and GSSG The equations and parameters used are derived from the literature ... evidence ofthe disease until the RBCs are exposed to oxidant stress The compensatory effect ofthe de novo GSH synthesis and GSSG export pathways may thus help to explain why many varieties of G6PD...
... they were submerged in the 1950s and 1960s, andthe number and diversity of these organisations have grown rapidly since the 1990s The re-emergence of NGOs raises the questions whether, andto ... belt between state and society which communicate government policies from the political elite down tothe lower levels of society andto voice the demands ofthe people tothe central power, ... treatment to NGOs depending on their nature andthe perception of whether they posed a political threat tothe government authority or help to promote public governance andthe delivery of social...
... deposits nonetheless exposed U.S taxpayers tothe risk of losswhile the profits made possible by deregulation and forbearance would accrue tothe owners and managers ofthe savings and loans The ... Examination ofthe Banking Crises ofthe 1980s and Early 1990s Volume I Reagan administration, the FHLBB andthe Office ofthe Comptroller ofthe Currency approved any application as long as the owners ... abandoned For a discussion of these issues, see Chapter 168 History ofthe EightiesLessons for the Future Chapter The Savings and Loan Crisis andItsRelationshipto Banking Table 4.2 S&L Failures,...
... on the vascular endothelium are biologically plausible because this is the site of protein C activation, the endothelium contains the receptor for APC (EPCR), andthe endothelium contains the ... protein C and endothelial barrier protection Another direct mechanism of action of APC on the endothelium is modulation ofthe endothelial monolayer, leading to increased cell-cell contact and decreased ... (inhibitor of apoptosis protein) and BCL-2, were upregulated by APC, whereas there was suppression ofthe apoptotic Page of (page number not for citation purposes) genes calreticulin and TRMP-2 Furthermore,...
... protozoa [44] These results prompted us to investigate the role of PPase enzymes in thedevelopmentand molting process of A suum larvae andto test whether this could be targeted by inhibitors ... the hypodermis ofthe body wall, which synthesizes components ofthe cuticle, may offer a useful target for studies into the mechanism ofthedevelopmentand molting process in the roundworms ... musculature The ecdysis of an old cuticle and deposition ofthe components of a new cuticle that are synthesized in the hypodermis and are secreted across the hypodermal membrane into the space...
... which conducts research and analysis for the Office ofthe Secretary of Defense, the Joint Staff, the Unified Commands, the defense agencies, the Department ofthe Navy, the U.S Intelligence Community, ... within the RAND National Security Research Division (NSRD) ofthe RAND Corporation NSRD conducts research and analysis for the Office ofthe Secretary of Defense, the Joint Staff, the Unified Commands, ... part, by donors and by the independent research anddevelopment provisions of RAND’s contracts for the operation ofits U.S Department of Defense federally funded research anddevelopment centers...
... determine the contribution of daily PA tothe HRQL of individuals with chronic stroke living in the community and 2) to assess therelationship between the functional ability (motor impairments of lower ... extremity, balance and walking distance) of these individuals tothe amount of daily PA they undertake This will enhance our understanding and identify the level of functional ability of individuals ... stroke motor severity and found to account for 13% (p = 0.02) ofthe total variance ofthe Physical Composite Score ofthe SF-36 Adding PA as assessed by the PASIPD resulted in an R2 change of 12%...
... operator P and give the e relation between T0 -periodic P C-mild solution andthe fixed point of P After showing the compactness ofthe Poincar´ operator P and obtaining the boundedness ofthe fixed ... sometimes andthe conditions for Banach fixed point theorem are too strong Our method is much different from others’, and we give a new way to show the existence of periodic solutions In addition, the ... number; and δ ∈ N τk δ denoted the number of impulsive points between and T0 The operator A is the infinitesimal generator of a C0 -semigroup {T t , t ≥ 0} on X; f is a T0 -periodic, with respect to...
... order to carry out the maximum photosynthesis, and this tends to be during the spring and part ofthe autumn During and after the appearance of shoots, the plant discards the old leaves, once the ... anterior toand posterior tothe mast year We may suppose that the internal cycle of acorn production at the corkoak forest of Polell takes at least five years 4.4 Therelationshipof litterfall and ... limiting factor andthe density ofthe crown is found to be balanced with the level of rainfall and soil reserves [14] This is clearly reflected in the positive correlation between rainfall andthe production...
... contributions JB and ET had full access to all ofthe study data and takes responsibility for the integrity ofthe data andthe accuracy ofthe data analysis Both authors contributed equally tothe study ... related tothedevelopmentof surgical site infections after major cardiac surgery Journal of Cardiothoracic Surgery 2011 6:4 Submit your next manuscript to BioMed Central and take full advantage of: ... inspired oxygen fraction tocardiac surgery patients in order to prevent SSIs In summary, the PaO2 in adult cardiac surgery patients is not related to SSI rate The strategy of administering supplemental...
... and B7 had all distorted markers skewed towards the heterozygote These groupings of distorted markers suggest that some regions ofthe chromosome are more prone to segregation distortion, rather ... example of synteny between A- and B- genomes of Arachis and Medicago An example of synteny between A- and B- genomes of Arachis and Medicago Alignment of linkage group B3 ofthe developed map with the ... accession of A ipaënsis However, regardless the taxonomic status ofthe species, it is clear that both genomes used to construct the map are similar tothe B-genome of A hypogaea and that the linkage...
... Description ofthe use of a web application in the consensus process for thedevelopmentofthe Control of Allergic Rhinitis and Asthma Test (CARAT) The data provide more details on thedevelopmentand ... reassembled and discussed all the questions, focusing on different aspects related tothe items and their importance, the wording ofthe questions, the response options andthe timeframe to be assessed ... CARAT – Control of Allergic Rhinitis and Asthma Test This is a translation to English oftheofthe preliminary version of Control of Allergic Rhinitis and Asthma Test, thedevelopmentof which is...
... proven to be the most accurate and can ensure the accuracy and stability ofthe hybrid method After explaining the combination scheme ofthe TDFEM and PSTD, some numerical examples are given The ... The hybrid methods TDFEM-PSTD, PSTD-FDTD and FMM-PSTD developed in this thesis improve the accuracy ofthe traditional PSTD method and preserve the efficiency ofthe PSTD algorithm They help to ... Although the PML absorber employed in PSTD and hybrid methods helped to reduce the wraparound effect, it cannot be eliminated and influences the accuracy ofthe PSTD method The other limitation of PSTD...
... cultures andthe expression is influenced by a number of factors including transfection efficiency ofthe given cell type, the quality and quantity of DNA taken up by the cells, the cytotoxicity ofthe ... sequesters NF-κB in the cytoplasm Activation of IKK leads tothe phosphorylation and degradation of IκB, resulting in the release and translocation of NF-κB from cytoplasm into the nucleus (Mercurio ... domains (EC) of IL-4Rα, γC or CD14 andthe TM/Cyt domains of TLR1 or TLR2 2.4.2 Expression vectors for the expression of fusion receptors between the EC domain of IL-4Rα or γC andthe FcγRIIA...
... transfer its momentum hq and energy ∆Eo tothe v v electrons ofthe solid The projection of q upon the surface kx determines the plasmon wave vector and, together with the dispersion relation, the ... schematic sketch ofthe cavity system considered in this chapter The distance ofthe center ofthe cavity tothe surface is h The major and minor axis ofthe cavity are denoted ˆ as a and b respectively ... specifically, the Maxwell equation for the considered cavity system was solved The solution shows the effect ofthe aspect ratio ofthe cavity on the field structure and spectral response ofthe system...