capital account liberalization and the role of the imf
Tài liệu Báo cáo khoa học: The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase) pptx
... must still be determined whetherits absence in the V79-G18 mutant is the result of the missingESSS subunit alone, or whether the absence of ESSS causes the f ailure of other integral membrane subunits ... the level of a complex of 46 subunits isdetermined. The activities of complex II and the downstream complexIII of the electron transport chain were measured and foundto be near normal in the ... culateabout the formation of supercomplexes and the effect of the absence of intact complex I, but the results are toopreliminary in this regard.Heterologous expression of the ESSS-HA subunit The localization...
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Tài liệu Báo cáo khoa học: The role of the SEA (sea urchin sperm protein, enterokinase and agrin) module in cleavage of membrane-tethered mucins pdf
... furtherinvestigate the role of the SEA domain in cleavage of membrane-tethered mucins we carried out site-directedmutagenesis of the FRPG ⁄ SVVV site and evaluatedhybrid mucins in which the ... modelling of the MUC1 SEA domain (Fig. 3). The model has the samea ⁄ b sandwich fold as the template SEA domain of mu-rine MUC16 [12] and consists of three a-helices and six b-strands. This ... to the first site. This is of particular interest aswe, and others, have detected multiple forms of the cytoplasmic tail of MUC1, MUC1FDTR and its deriv-atives [9,13]. Further, the migration of...
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Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx
... that if the role of GTP wassolely to increase the rate of glutamine hydrolysis, therewould have been no effect of adding GTP when the rate of CTP synthesis was limited by the concentration of nucleotide ... locks the enzyme in the active form for CTP synthesis and thereby stimulates the kcat of the reaction. Since GTP actually willactivate the uncoupled glutaminase reaction the structure of the monomer ... 4C and Table 2).In another experiment similar to that in Fig. 4C, the GTPactivation of the glutaminase reaction and CTP synthesiswas compared (Fig. 5). In the absence of GTP, the rate of glutamine...
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The Role of the Media in Promoting and Reducing Tobacco Use doc
... the rationale for the monograph’s organization and presents the key issues and conclusions of the research as a whole and of the individual chapters. This section describes media research theories ... examine the dynamics of tobacco-related media interventions at each of these levels, within a systemic framework. The relationships among these levels and stakeholders on either side of the tobacco ... experiments, however, are often limited in terms of the rather forced nature of exposure, unnatural viewing situations, and the limitations of the experimental populations, which are often college students....
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Báo cáo khoa học: Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization pdf
... GavÞ2rð4Þwhere Ri and Gi are the red and green intensities of voxelI, respectively, and Rav and Gav the average values of Ri and Gi, respectively.It is used for describing the correlation of the intensitydistributions ... indicatedbasic region of ic3 of the D2receptor and acidic region of the C-tail of the D1receptor might be involved in the interactions between the two dopamine receptors.In addition, the subcellular ... D2R and cyan fluorescent protein-tagged D1R mayresult from differing localization of these proteins in the cell rather thanfrom the possible role of the D2R basic domain in the mechanism of D1–D2receptor...
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Báo cáo khoa học: Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3) docx
... the c-phosphate of the bound nucleotide across the dimer [15] and the aromatic residue of the A-loopstacks against the adenine moiety of boundnucleotide and provides further stabilization and specificity ... cleavage of the c-phosphate does occur in the NBD with the mutation at the IC [36,38,39]. More-over, these and other studies suggest that the ICresidues are involved in the formation of the NBDdimer, ... motifs: the Walker A and B motifs, the signature or LSGGQ motif and the A-, D-, H- and Q-loops. These motifs are positionedaround the bound nucleotide and help to position and maintain it in the...
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Báo cáo khoa học: The essential tyrosine-containing loop conformation and the role of the C-terminal multi-helix region in eukaryotic phenylalanine ammonia-lyases docx
... moredetail.Results and discussionModeling the active conformation of the essential Tyr110-loop of parsley PALBecause of the uncertainty of the arrangement and the role of the essential Tyr110-loop in recent ... putida [33] and Bacillus subtilis [34], respectively. On the basis of the functional similarity of HAL and PAL, of the sameelectrophilic prosthetic group at the active sites, and of the sequence ... of Tyr110 more than 17 A˚apart from the exocyclicmethylene C-atom of the MIO prosthetic group.On the basis of the experimental structures, hypothe-ses on the role of the Tyr110-loop have been put...
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Báo cáo khoa học: Carbohydrate binding sites in Candida albicans exo-b-1,3-glucanase and the role of the Phe-Phe ‘clamp’ at the active site entrance ppt
... seen for the Phe triad in the structure of the mutant Exg:L3 complex. Neither of the two sugar residues interacting with the Trp triadoverlaps with the sugar seen in the Phe-Phe clamp of Exg.Structural ... Rearrange-ment of the water molecules in and around the clampregion as seen in the crystal structure may be relevant. The relative activities of the mutants tested showed the same trend for both the hydrolysis ... identified (three in the active site and two on the outside of the protein).DiscussionExamination of the previously determined crystalstructures of native and inhibited forms of Exg fromC. albicans...
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Transforming the Face of Health Professions Through Cultural and Linguistic Competence Education: The Role of the HRSA Centers of Excellence potx
... The Role of the HRSA Centers of Excellence,” is one result of the efforts of HRSA and the COEs. The publication of this guide is a significant achievement brought about by the efforts of a large ... role of the cultural context in the expression and evaluation of symptoms and dysfunction, and the effect that cultural differences may have on the relationship between the individual and the ... When the COEs opened, the directors and staff of the centers immediately understood the tremendous challenge of the cultural and linguistic competence mandate. Among the COEs, for example, there...
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Mammographic density and breast cancer risk: the role of the fat surrounding the fibroglandular tissue pdf
... more insight into the role of the fat breast tis-sue, we investigated the independent effects of the size of dense tissue and the size of non-dense tissue in the breast and their combined effects ... is, mother or sister (no/yes), height and BMI. Toinvestigate the independent effects of the dense and the non-dense areas, the analyses of the dense area were addi-tionally adjusted for the non-dense ... studies have investigated the role of the breast fat tissue with different results. Stone et al. investi-gated the role of the non-dense area in a group of womenin the United Kingdom comparable...
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WORKING PAPER NO. 218 THE ZERO-INTEREST-RATE BOUND AND THE ROLE OF THE EXCHANGE RATE FOR MONETARY POLICY IN JAPAN potx
... downward bias in the variability of the real rate depending on the level of the nominal equilibrium rate of interest. The downward bias in the variability of the real rate accounts for the reduced ... above, the distortion of output and inflation distributions is driven by adistortion of the real interest rate. The left-hand panels of Figure 5 report the upward biasin the mean real rate and the ... that the central bank adopts the proposal in the 11th period of the simulation. Important choice variables are the initial price level of the implied target path, the extent of the devaluation and...
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Báo cáo khoa học: Autophosphorylation of heme-regulated eukaryotic initiation factor 2a kinase and the role of the modification in catalysis doc
... examined the catalytic activities of dephos-phorylated HRI, and compared the catalytic and heme-sensing properties of phosphorylated and dephosphorylated HRIs. The effects of heme on the kinase ... (2008) Elucidation of the heme-binding site of heme-regulated eIF2a kinase(HRI) and the role of the regulatory motif in hemesensing by spectroscopic and catalytic studies of mutantproteins. ... toexplore the role of autophosphorylation of the HRIprotein in the intramolecular protein–protein interac-tion (between the NTD and KD) and catalysis uponheme binding. Identification of autophosphorylatedsites...
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Vietnam’s Competitiveness and the Role of the Private Sector potx
... countries?• What is the unique competitive position of the nation or region given its location, legacy, and existing and potential strengths?– What roles with neighbors, the region, and the broader ... 2007 © Professor Michael E. Porter20081201 – PACE strategy.ppt The Role of Business in Social Issues• Business cannot solve all of society’s problems, nor bear the cost of doing so– There are ... depends on improving the microeconomic capability of the economy and the sophistication of local competitionDeterminants of CompetitivenessNatural Endowments16Copyright 2007 © Professor Michael...
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The Role Of The United States Postal Service In Public Safety And Security doc
... points across the United States, six days per week, from the areas with the highest rates of crime to the bottom of the Grand Canyon (USPS, 2008d, p. 32; USPS, 2008a).xxvi The Role of the United ... part of mandatory training. Man-agers and supervisors also deliver monthly mandatory talks to USPS employees nationally that focus on the use of SLAP guidance and the 60 The Role of the United ... firsthand about the training, guid-ance, policies, procedures, and technology they currently use to pro-tect the safety and security of their employees, their customers, and their deliveries....
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aggarwal and conroy-price discovery in initial public offerings and the role of the lead underwriter
... between the opening price on day 1 and the offer price; offer-to-close return is the percentage difference between the closing price on day 1 and the offer. The mean and median number of comanagers ... more IPOs. The table is sorted by mean startingtime. The name of the lead underwriter, the number of IPOs done by them ~N !, the mean and median starting time for the IPOs, the earliest and latest ... quoting and trading the stock. We use unique quote data with the identity of the marketmaker to examine the quoting behavior of the lead underwriter during the preopening period; the behavior of other...
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