cao thủ học đường lord of study tập 1 full
Báo cáo y học: "Early Effects of anti-inflammatory [1, 2, 4]triazolo[4, 3-a] [1, 8]naphthyridine derivatives on human stimulated PMN and endothelial cells: an in vitro study" doc
... Control 58 ± 18 888 ± 30IL -1 280 ± 29 33 91 ± 98 IL -1 275 ± 22 4055 ± 22NF1 61 10-4M 295 ± 31 3508 ± 82 NF1 61 10-4M 288 ± 17 3990 ± 38NF1 61 10-5M 285 ± 23 3330 ± 49 NF1 61 10-5M 277 ... 3885 ± 33NF1 61 10-6M 288 ± 28 3452 ± 74 NF1 61 10-6M 280 ± 22 3905 ± 55NF177 10 -4M 260 ± 21 3660 ± 84 NF177 10 -4M 268 ± 17 3875 ± 42NF177 10 -5M 277 ± 15 3280 ± 94 NF177 10 -5M 256 ... for 20 h with IL -1 plus either NF177 or NF1 61 (10 -6 10 -4M). In a second set of experiments, HUVECwere pre-treated with IL -1 for 20 h and then with NF177or NF1 61 (10 -6 10 -4M) for a further...
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Tài liệu Báo cáo khoa học: Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis docx
... & Laursen RA (19 81) Immuno-chemical characterization of the kringle 4 fragment of human plasminogen. J Biol Chem 256, 11 166 11 1 71. 46 Cummings HS & Castellino FJ (19 85) A monoclonalantibody ... tothe study of the activation pathways of plasminogen invivo. J Biol Chem 260, 12 106 12 111 .57 Wiman B & Wallen P (19 73) Activation of human plas-minogen by an insoluble derivative of urokinase. ... F-75877-Cdx, Paris 18 , FranceFax: +33 1 40 25 86 10 Tel: +33 1 40 25 86 11 E-mail: angles@infobiogen.fr(Received 30 March 2005, revised 5 May2005, accepted 9 May 2005)doi :10 .11 11/ j .17 42-4658.2005.04754.xPlasmin(ogen)...
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Báo cáo khoa học: Functional association of human Ki-1⁄57 with pre-mRNA splicing events docx
... without dotsn = 3Ki -1/ 57 Ki -1/ 57 (1 222)Ki -1/ 57 (1 413 )BALCDEFGH I JKKi -1/ 57 (1 222) Ki -1/ 57 (12 2– 413 ) Ki -1/ 57 (15 1–263) Ki -1/ 57(264– 413 )Fig. 8. The localization of Ki -1 ⁄ 57 to nuclearbodies ... Scolfaro 10 .000, C.P. 619 2, 13 084-9 71 Campinas,SP, BrasilFax: +55 19 3 512 10 06Tel: +55 19 3 512 11 25E-mail: jkobarg@lnls.br(Received 12 April 2009, revised 8 May2009, accepted 13 May 2009)doi :10 .11 11/ j .17 42-4658.2009.07092.xThe ... GST–hnRNPQ (1 443), GST–Ki -1 ⁄ 57 and the trun-cated constructs Ki -1 ⁄ 57 (12 2– 413 ), Ki -1 ⁄ 57 (15 1–260) andKi -1 ⁄ 57(2 61 413 ) fused to 6· His were expressed inEscherichia coli BL 21- CodonPlus-RIL...
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Báo cáo khoa học: Mutational analyses of human eIF5A-1 – identification of amino acid residues critical for eIF5A activity and hypusine modification doc
... D11A, G13A, S15A, T17A, P19A,C22A, P37A, C38A, M43A, K47A, K47D, K47R, G49A,K50A, K50D, K50I, K50R, H51A, G52A, K55A, F64A,P74A, H77A, M79A, P82A, I84A, R86A, L91A, L101A,P 115 A, E 116 A, L 119 A, ... (K47A), 11 3.8 ± 10 .8 (K47R), 238.7 ± 11 .3 (H51A), 14 4.5 ± 14 .2 (P74A), 15 0 .1 ± 12 .5 (L91A) and444.0 ± 32.6 min (L101A), whereas that for the strainexpressing wild-type heIF5A was 11 2.3 ± 6.8 ... (pBM–TIF51A)(p 414 GAL1–heIF5A-1m)This workHHY 212 S MATa leu2 his3 ura3 trp1can1 tif51A:: LEU2tif51B::HIS3 (p 414 GAL1–heIF5A-1m)This workUBHY-R 212 d MATa leu2 his3 ura3 trp1can1 tif51A:: LEU2tif51B::HIS3...
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Báo cáo khoa học: Crystal structure of heme oxygenase-1 from cyanobacterium Synechocystis sp. PCC 6803 in complex with heme pot
... HO -1. Gly130,Gly134, Gly135, and Asp1 31 correspond to Gly139, Gly143, Gly144, and Asp140 in human and rat HO-1s and to Gly135, Gly139, Gly140, andAsp136 in HmuO.F-helix confomation Gly130 ... accession code 1WE1.(Received 1 1 August 2 004, revised 30 September 2004,accepted 4 October 2004)Eur. J. Biochem. 2 71, 4 517 –4525 (2004) Ó FEBS 2004 doi :10 .11 11/ j .14 32 -10 33.2004.04 411 .x helix ... O–Fe Gly134 N–Fe Gly130 O–Gly134 N Gly130 O–Gly135 N Asp1 31 O–Gly135 NSyn HO -1 closed 4.6–4.9 5 .1 5.4 2.8–3.0 4.0–4 .1 2.9–3.0Human HO -1 closed 4.8 5.3 3.2 4.3 3 .1 Human HO -1 open 4.9 6.0 3 .1 4.8...
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Báo cáo khoa học: Expression studies of the core+1 protein of the hepatitis C virus 1a in mammalian cells pot
... anti-core +1 pHPI -15 07anti-core.... 14 2024ControlpHPI -14 95pHPI -14 94pHPI -15 07kDaMG132 1 2 3 47 17 1 2 3 4 5 6 7anti-core +1 ControlpHPI -14 96pHPI -14 96+MG132+MG132+MG132pHPI -15 79pHPI -15 79pHPI -15 80pHPI -15 80(a)(b)(a)(b) ... gcccctctATG85gnt 515 nt 825nt ntnt ntcore +1 myc ( +1) nt ntpHPI -14 96core +1/ S–myc 1 2 3 4anti-core +1 7 17 ControlpHPI -14 95pHPI -14 94pHPI -15 07kDaMG132DMSOLactacystinMG132 1 2 3 anti-core +1 pHPI -15 07anti-core.... 14 2024ControlpHPI -14 95pHPI -14 94pHPI -15 07kDaMG132 1 ... ntcore +1 myc( +1) nt ntdel. core nts 342- 514 pHPI -14 95nt 515 nt 825nt ntnt ntcore +1 myc( +1) nt ntdel. core nts 342- 514 pHPI -14 95pHPI -15 80CMVCMVnt 590 nt 828nt ntnt ntcore +1 nt ntcore +1/ Soptimal...
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Báo cáo khoa học: Solution structure of an M-1 conotoxin with a novel disulfide linkage pdf
... 3.53Gly7 8 .18 4.58, 3. 31 Cys8 8.42 4.7 3.06His9 7.3 4.89 3.53, 3.26 d: 7.29e: 8.67Glu10 8.92 4 .15 2 .13 c: 2.55Leu 11 8.45 4.08 2. 01, 1. 72 c: 1. 61 d: 0.94 ± 0.89Cys12 7.57 4.46 3.22, 3 .17 Tyr13 9.08 ... NumberIntraresidual 12 2Sequential (|I ) j | ẳ 1) 48Medium range 7Long range 13 AMBER energies, kcalặmol )1 Bond 2.822 ± 0 .13 6Angle 34. 311 ± 1. 454Dihedral 36 .11 4 ± 2.807VDW )55.829 ± 1. 478EEL )442.969 ± 13 .886H-bond ... ChineseAcademy of Sciences, 320 YueYang Road,Shanghai 2000 31, ChinaFax: +86 21 5492 10 11 Tel: +86 21 5492 11 65E-mail: chi@sunm.shcnc.ac.cn*These authors contributed equally to this study (Received 10 ...
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Báo cáo Y học: NMR structure of the HIV-1 regulatory protein Vpr in H2O/trifluoroethanol Comparison with the Vpr N-terminal (1–51) and C-terminal (52–96) domains pot
... M. (19 94) The Vpr protein of human immunodeficiency virus type 1 influences nuclear locali-zation of viral nucleic acids in nondividing host cells. Proc. NatlAcad.Sci.USA 91, 7 311 –7 315 . 11 . Nie, ... type 1 forms cation-selective channels in planar lipid bilayers. Proc. NatlAcad.Sci.USA93, 11 1 11 5.Ó FEBS 2002 NMR Structure of the HIV -1 protein Vpr (Eur. J. Biochem. 269) 3787 (Val57, Leu 61, ... asemipreparative Vydac C 18 column using a linear gradient of acetonitrile. An experimental mass of 11 4 31. 92 Da wasobtained by electrospray mass spectroscopy and a mass of 11 433.02 Da was calculated...
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Báo cáo sinh học: "The impact of Metastasis Suppressor-1, MTSS1, on oesophageal squamous cell carcinoma and its clinical significance" doc
... tumour suppresor -1, MTSS -1 and the aggressiveness of prostate cancer cells. Exp Therapeut Med 2 011 ,2 :15 7 -16 2.doi :10 .11 86 /14 79-5876-9-95Cite this article as: Xie et al.: The impact of Metastasis ... 87Female 18 Age > 55 64≤ 55 41 T status 1 1225356 419 N status 0 48 1/ 2 53M status 0 99 12 WHO grade 1 72463 41 47Xie et al . Journal of Translational Medicine 2 011 , 9:95http://www.translational-medicine.com/content/9 /1/ 95Page ... tumours (48 .19 ± 16 .07) (p = 0.024).Xie et al . Journal of Translational Medicine 2 011 , 9:95http://www.translational-medicine.com/content/9 /1/ 95Page 4 of 10 RESEARCH Open AccessThe impact of Metastasis...
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o cáo hóa học:" The impact of Metastasis Suppressor-1, MTSS1, on oesophageal squamous cell carcinoma and its clinical significance" docx
... tumour suppresor -1, MTSS -1 and the aggressiveness of prostate cancer cells. Exp Therapeut Med 2 011 ,2 :15 7 -16 2.doi :10 .11 86 /14 79-5876-9-95Cite this article as: Xie et al.: The impact of Metastasis ... 87Female 18 Age > 55 64≤ 55 41 T status 1 1225356 419 N status 0 48 1/ 2 53M status 0 99 12 WHO grade 1 72463 41 47Xie et al . Journal of Translational Medicine 2 011 , 9:95http://www.translational-medicine.com/content/9 /1/ 95Page ... tumours (48 .19 ± 16 .07) (p = 0.024).Xie et al . Journal of Translational Medicine 2 011 , 9:95http://www.translational-medicine.com/content/9 /1/ 95Page 4 of 10 significantly reduced rate of growth...
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Báo cáo toán học: "Asymptotic Enumeration of Dense 0-1 Matrices with Equal Row Sums and Equal Column Sums" docx
... T 1 2(S), are these:Q =|j|n 1/ 2+,j =1, ,m1|k|m 1/ 2+,k =1, ,n1|à|(mn) 1/ 2+2M =|à 1 |m 1/ 2n 1/ 2+| 1 |n 1/ 2m 1/ 2+B = (1 m 1/ 4)2 à2 (1 + m 1/ 4)2 (1 n 1/ 4)2 ... of 1 2QE2andO(H 1 )exp 1 2+ 1 8A 1 (1 2)2+ 1 16A 1 (1 6 +62)mn+nmìAmn 1/ 2An(m1)/2Am(n1)/2isexp 1 2 1 2A24Amn+nm 1+ O(n 1/ 4+/24+4+o (1) )+O(n 1/ 2+/3 +15 /2+22)ìAmn 1/ 2An(m1)/2Am(n1)/2,which ... abbreviationsc2= 1 m 1/ 2(m 1/ 2 +1) 2,c3=m 1/ 2+3m(m 1/ 2 +1) 3,d2= 1 n 1/ 2(n 1/ 2 +1) 2,d3=n 1/ 2+3n(n 1/ 2 +1) 3.The determinant of the matrix T2is (mn) 1/ 2,andsoJ(m, n)=(mn) 1/ 2T 1 2(S)E 1 ,where E 1 =exp(L 1 ), andL 1 =...
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Báo cáo khoa học: " Sequence Analysis of Canine LINE-1 Elements and p53 Gene in Canine Transmissible Venereal Tumor" doc
... Acad. S ci. U.S .A. 19 97,94, 10 155 -10 160. 14 .Levine, A. J., Momand, J. and Finlay, C. A.Thep53 tumour supressor gene. Nature 19 91, 3 51 , 453-456. 15 .McClure, M. A.Evolution of retroposons by ... originate from the 3 region of canine LINE -1. Katzir et al. [11 , 12 ] reported that the 1, 314 -bp LINE -1- like element flanked by 10 -bp direct repeatsintegrate into the c-myc region of TVT, which is 64-bpsmaller ... Rev.Biochem. 19 82, 51 , 813 -844. 10 .Johnson, A. S., Couto, C. G., Weghorst, C. M.Mutation of the p53 tumor suppressor gene in spontaneouslyoccurring osteosarcomas of the dog. Carcinogenesis 19 98, 19 (1) ,...
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Báo cáo y học: "Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factor" ppt
... appears in EMBO J 19 97, 16 :440]. Embo J 19 93, 12 :3893-39 01. 37. Benbow U, Brinckerhoff CE: The AP -1 site and MMP gene reg-ulation: what is all the fuss about? Matrix Biol 19 97, 15 : 519 -526.38. Chamberlain ... fibroblasts. Arthritis Rheum 19 98, 41: 1987 -19 94. 31. Xiao G, Harhaj EW, Sun SC: NF-kappaB-inducing kinase regu-lates the processing of NF-kappaB2 p100. Mol Cell 20 01, 7:4 01- 409.32. Heissmeyer V, ... Oncogene 19 95, 10 : 12 09 -12 16.25. O’Hagan RC, Tozer RG, Symons M, McCormick F, Hassell JA:The activity of the Ets transcription factor PEA3 is regulatedby two distinct MAPK cascades. Oncogene 19 96,...
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Báo cáo y học: "Serum levels of matrix metalloproteinases -1,-2,-3 and -9 in thoracic aortic diseases and acute myocardial ischemia" potx
... 11 .79Aneurysm 18 15 6.64 ± 9 .16 Myocardial ischemia 13 18 0.94 ± 15 .49Healthy individuals 15 17 1.37 ± 11 .39Total 95 16 3.59 ± 4.58MMP-3 Acute aortic dissection 31 12.92 ± 1. 01 Chronic aortic dissection 18 ... C(n = 18 )Group D(n = 13 )Group E(n = 15 )Age mean ± SD 60 .1 ± 14 .8 60.6 ± 13 .1 60.7 ± 13 .7 65.4 ± 10 .3 40 .1 ± 5.2Male/Female 26/8 17 /1 14/4 13 /0 3 /12 Arterial hypertension (%) 22 (64.7%) 13 ... 3 .16 ± 0. 51 Myocardial ischemia 13 4.58 ± 1. 04Healthy individuals 15 1. 10 ± 0.38Total 95 2.95 ± 0.34MMP-2 Acute aortic dissection 31 1 51. 62 ± 6.82Chronic aortic dissection 18 17 2 .12 ± 11 .79Aneurysm...
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