... FEBS 2003 Minor isomer ofthe Hex3 glycoform (estimated from the intensity ofthe fragments in b a Major isomer ofthe Hex3 glycoform (estimated from the intensity ofthe fragments in MS2 experiments) ... on the basis of spin-connectivity pathways delineated inthe 1H chemical shift correlation maps, the chemical shift values, andthe vicinal coupling constants From the glycoform compositions of ... observed corresponding to glycoforms containing only one PEtn group or containing one PEtn group and a phosphate group In order to obtain sequence andbranching information, the OS fractions were...
... Treatment against Cirrhosis), is a multicenter study ofthe potential benefit of prolonged peginterferon therapy in mitigating the progression of fibrotic liver disease [8] In this study, 391 ofthe 1045 ... poorer transplant outcome, andthe difficulties in treatment ofthe infection following LT [12], it is reasonable to emphasize the importance of pretransplant treatment of HCV The International Liver ... rigorously in a randomized controlled format to assess their value and impact on efficacy of therapy although they are now widely used in patients receiving interferon therapy Treatment of advanced...
... the differences inthe behaviors and attitudes ofthe grandmother, the father andthe mother andthe children at least cause discontent to one another The grandmother held the floor most ofthe ... character and setting Technique has to with the structuring ofthe story into the plot so that the writer can convey the theme andthe manipulating ofthe language in order to express the ideas ofthe ... from the beginning ofthe story in her decision where to go, in her introduction ofthe scenery along the journey While the father, the mother andthe children enjoyed going to Florida, The grandmother...
... Conclusions, including the results ofthe November 2001 Workshop Management Framework - Introd uced Marine Pests Management capabilities and approaches APEC andthe MRCWG have a role in liaising with ... Within APEC little is known on the introduction of marine pests Little practical information on measures to prevent introductions Lack of knowledge in what individual countries are doing ... NACA to enhance the effectiveness of existing instruments within APEC Institutional arrangements for managing the marine environment is fragmented in most economies Baseline surveys to identify...
... nuclear issues in general, the feeling grew inthe environmental movement that Yeltsin was increasingly yielding to the demands ofthe Ministry of Atomic Power andthe nuclear-industrial lobby.99 ... not having regulative authority, an agency under the Ministry of Health was included inthe drafting of these health standards throughout the Soviet period.82 Involving the same agencies, these ... After having ascribed a 1993 incident of dumping of liquid radioactive waste inthe Sea of Japan to irresponsibility on the part ofthe Navy andthe nuclear industry, the Russian Minister of Environment...
... emigrated, and were either residing in our Colonies or in other parts ofthe world, andthe only method I could discover of obtaining information regarding several of viil INTRODUCTION them, was ... captain ofthe John +, a boat which has often played a prominent part inthe struggles ofthe Isis, and which has served as the training-school for no fewer than ten ofthe Crews which during the ... can in no possible way be traced to the effects of rowing, we come to the consideration of those diseases ofthe respiratory andthe circulatory systems (in other words ofthe lungs andof the...
... useful in determining a) the efficacy of BCG vaccine in HCWs or b) the effects on efficacy ofthe vaccine strain administered Vol 45 / No RR-4 MMWR andthe vaccinee’s age at the time of vaccination ... resurgence inthe incidence of TB occurred inthe United States and included increases inthe number of TB cases among adults and children and outbreaks of multidrug-resistant TB (MDR-TB) involving ... million vaccinees in Sweden and Finland, respectively (46 ) Regional increases inthe incidence of BCG osteitis have been noted following changes in either the vaccine strain or the method TABLE...
... discovery of a brain-specific MT isoform, GIF, in 1991, sparked considerable interest in understanding the role of all MTs inthe brain, and particularly within the injured or diseased brain Inthe ... studies examining the role of GIF in AD, linked to its initial discovery as a factor deficient inthe AD brain There remains no clear consensus on the role of GIF inthe pathogenesis of AD, and therefore ... whether GIF acts in a neuroinhibitory manner when administered directly into the brain following traumatic brain injury In one such study, the injection of GIF into the site of a stab wound promoted...
... basis points ofthe 11 basis-point decline inthe average expense ratio of funds of funds over the period (labeled in Figure 13 as “Fall in expense ratios of individual funds”) By definition, the ... inflation by taking the fee breakpoints available in 2010 and multiplying by the Consumer Price Index in December 2000 and dividing by the Consumer Price Index in December 2010 The front-end ... endowments, and other institutional investors investing for their own accounts, rather than on behalf of retail investors Stock Funds The average fees and expenses paid by stock fund investors declined...
... declined in 2011 owing to declines inthe expense ratios of individual funds, an increase inthe demand for index funds, and a continuing shift by investors in both actively managed and index ... percentage ofthe assets that the financial professional manages for an investor, rather than as a percent ofthe dollars initially invested Over time, brokers and other financial professionals ... collects the 12b-1 fee, passing the bulk of it to the financial professionals serving fund investors Alternatively, investors may pay the professional an asset-based fee directly In such cases, the...
... concerning the kinetics and properties ofthe enzyme More strikingly, we show a novel role ofthe PPase enzyme inthe development and molting process of A suum larvae in vitro constructed in UniZap ... immunohistochemical staining), and that the inhibition of PPasecatalyzed PPi hydrolysis by these inhibitors, is likely to prevent the synthesis ofthe new cuticle from the hypodermis and/ or ecdysis ofthe old ... presence of increasing concentrations of inhibitors for 10 days, andthe number of molting larvae was determined Molting was manifested by shedding ofthe L3 cuticle Results Identification of cDNA...
... Thailand from Malaya in 1900 and planted in Trang province in southern Thailand (RFD 2000) Estate agriculture was for political reasons discouraged in Thailand, unlike in Malaya, inthe beginning ... pineapple and upland rice (RRIT 2005) Cherdchom et al (2002) reported four main integrated rubber farming systems inthe South of Thailand emerging during the financial crisis inthe late 19 1990's The ... farming systems vary within Southeast Asia Inthe beginning ofthe 20th century, estate planting was encouraged in Malaya, while in Thailand andthe Netherlands Indies rubber became an important crop...
... ONE is the INTRODUCTION This includes an outline ofthe CONTEXT and main themes, the motivation and purpose ofthe study - the why and how PART TWO is THE REASEARCH - METHODOLOGY and FINDINGS PART ... component inthe integration process: The first step towards the integration of refugees must be to identify and help with their most pressing needs Finding and settling them into safe and appropriate ... GUIDE is the last section This provides a discussion ofthe main themes as they emerged inthe service user interviews (as listed above inthe ‘Findings’ section) It breaks the themes down into manageable...
... treatment On the other hand, the findings from this survey indicate that pastoral communities living in both ofthe study areas had basic awareness about the symptoms and treatment of PTB, which ... hindered an in- depth analysis ofthe results Hence, the findings from the qualitative portion ofthe study might be considered preliminary Page 10 of 11 Conclusion Our findings indicate that the majority ... smoking/chewing Khat, which is similar to the beliefs found in a previous study in another part of Ethiopia [19] While the community perception about the role of starvation and smoking as the...
... (disordered inthe ligand-free state in YbgJ) Inthe absence ofthe ligand, the lid part is separated from the active site, which leads to a more open active site Upon the binding of ligand inthe acyl-enzyme ... conformations ofthe regions at 100-105 and 303-309 aa inthe N form, and we investigated the following points First, these areas are not involved in any contacts with other molecules in crystals in all the ... basis of their crystal structures andthe conserved amino acid residues (aa) of their active sites, these glutaminases are classified into a large group of bacterial penicillin-binding proteins and...
... once into the idea ofthe children in regard to them, and treated them always as if they were real persons; often speaking of them and to them, inthe presence ofthe other children, inthe most ... upon the piazza with blocks and other playthings, and finally had gone into the house, leaving all the things on the floor ofthe piazza, instead of putting them away in their places, as they ... had been enjoined upon them as, for example, when they left the door open in coming in or going out, inthe winter; or interrupted their mother when she was reading, instead of standing quietly...
... even inthe absence of fibrin or cells PAN–K5 binding is mediated via the aminohexyl (AH) site in K5 [28,29] (Fig 3) Unlike lysine-binding sites in K1, K2 and K4 of plasminogen, the AH site can bind ... promoting fibrin binding of Glu-plasminogen Although the structural difference between complestatin and chloropeptin I is only at the position ofthe C–C bond that connects the indole ring ofthe ... formation of tcu-PA and plasmin The surfactin C action involves modulation of Glu-plasminogen activation through relaxing the conformation ofthe protein Surfactin C increases the intrinsic fluorescence...
... shown in Fig 1B, the distance between the two termini ofthe inserted Ca2+-binding sites inthe model structure ofthe EF-hand of STIM1 is within ˚ 15 A Accordingly, a total of six glycine linkers ... Ca2+-coordinating loop positions and was introduced to perturb the Ca2+-binding ability ofthe grafted EF-hand of STIM1 (B) Modelled structure ofthe engineered protein with the grafted EF-hand Ca2+-binding ... EF-hand motif in STIM1 is occupied by Ca2+ Removing the proposed Ca2+-coordinating residues in positions andofthe EF-hand motif significantly compromised the metal-binding capability ofthe engineered...
... However, inthe case of Bb, the cellular activity was decreased and secretion was increased, suggesting that the presence of this cysteine retains the enzyme intracellularly In case of Aa, the cellular ... higher mass of BChE subunits [37] This indicates a predominant in uence ofthe catalytic domain on oligomerization Mutation ofthe cysteine located at )4 from the C-terminus to a serine inthe a or ... of hydrolysis of acetylthiocholine and butyrylthiocholine (at mm) by BChE were approximately 14% and 24% ofthe rate of hydrolysis of acetylthiocholine (at mm) by AChE In uence ofthe C-terminal...