biodiversity conservation economic development and drug discovery in suriname

Rooted in Poverty?: Terrorism, Poor Economic Development, and Social Cleavages docx

Ngày tải lên : 23/03/2014, 20:20

... rapid increase in population puts a considerable strain on the economic and political system of a county and may be accompanied by a rise in all criminal activity, including terrorism.46 Finally, ... studying political violence, including Samuel Huntington,14 who borrows from the relative deprivation framework to explain the increase in political violence witnessed in the United States and in ... a declining measure indicates a process of liberalization or declining repression The expectations about the relationship between ‘‘Repression’’ and ‘‘DRepression’’ and the incidence and intensity...

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Báo cáo y học: " Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya" doc

Ngày tải lên : 10/08/2014, 05:21

... molecular work and sequence analysis and prepared the manuscript SL and CV assisted in designing the study and drafting the manuscript KD and JR performed viral loads and genotyping KM supervised ... Prevalence and risk factors for developing K65R mutations among HIV-1 infected patients who fail an initial regimen of fixed-dose combination of stavudine, lamivudine, and nevirapine J Clin Virol ... genotyping of HIV RNA was performed by nested RT-PCR and an in- house sequencing assay as described elsewhere [4] The interpretations of genotyping data and subtyping were performed using Smartgene™...

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Báo cáo y học: "Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery" doc

Ngày tải lên : 14/08/2014, 08:20

... ligand-protein binding Power-law behaviors of ligand-protein binding The number of ligands (N) decays with an increase in the number (L) of (a) domains and (b) folds that bind the ligand and ... during protein folding [74,75] Thus, the free energy release during ligand binding may meet the free energy demand during protein folding It is tempting to examine the conjecture of ligand-induced ... protein-ligand binding ture-function relationships of proteins First, binding sites and ligands are quite flexible and plastic [39-41], and therefore, binding-site selection is, to certain extent,...

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Development of database and computational methods for disease detection and drug discovery

Ngày tải lên : 10/09/2015, 09:04

... Bioinformatics and cheminformatics in drug discovery The combination of random screening and rational drug design have played an important role in drug discovery [44] The traditional drug discovery ... 1.2 Bioinformatics and cheminformatics in drug discovery 1.3 Introduction of bioinformatics and cheminformatics database development 11 1.4 Overview of virtual screening in drug discovery ... Description Web link BindingDB Binding affinities of proteins and http://www.bindingdb.org/bind/index.jsp protein ligand MDDR http://accelrys.com/products/databases/bioa molecules PubChem Information...

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Human embryonic stem cells as a cellular model for osteogenesis in implant testing and drug discovery

Ngày tải lên : 16/10/2015, 15:38

... These included substituted purines, pyrimidines, indoles, quinazolines, pyrazines, pyrrolopyrimidines, pyrazolopyrimidines, phthalazines, pyridazines and quinoxalines[55] High-throughput screens ... They repeatedly introduce certain proteins channeled into the cells via poly-arginine anchors and sufficiently induced pluripotency[45] This new technique brings in new hope in stem cell research ... mounting (containing Dapi, Invitrogen) was performed to stain the nucleus Staining was examined under fluorescent microscope (Olympus IX70, Tokyo, Japan) 2.1.6 Teratoma formation and staining...

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Tài liệu Research " THE ROLE OF EDUCATION IN ECONOMIC TRANSITION AND POLITICAL TRANSFORMATION IN POST-COMMUNIST COUNTRIES " ppt

Ngày tải lên : 18/02/2014, 11:20

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Tài liệu Local Democracy, Economic Development and Construction Bill [HL] docx

Ngày tải lên : 21/02/2014, 00:20

... housing in England, or (b) tenants of social housing and other residential property in England The function in this subsection is that of conducting or commissioning research into issues affecting— ... appointing authority, any person who is a partner authority in relation to the appointing authority (7) (9) 32 Any local authority and any joint overview and scrutiny committee must, in exercising ... can take part in those democratic arrangements and what is involved in taking part 54/4 10 Local Democracy, Economic Development and Construction Bill [HL] Part — Democracy and involvement Chapter...

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Báo cáo khoa học: Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1 pot

Ngày tải lên : 06/03/2014, 22:21

... labelling intensity observed with the single-cysteine-containing isoforms Obtaining full labelling and its accurate quantitation are difficult to achieve in practice, resulting in occasional instances ... were examined by introducing cysteines at distinct positions in TM12 and assessing their accessibility to covalent modification with thiol-reactive probes In order to determine how changes in the ... substrate-induced fit mechanism for drug binding J Biol Chem 278, 13603–13606 Loo TW, Bartlett MC & Clarke DM (2003) Simultaneous binding of two different drugs in the binding pocket of the human multidrug...

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Báo cáo khoa học: Transcript proﬁling reveals diverse roles of auxin-responsive genes during reproductive development and abiotic stress in rice pdf

Ngày tải lên : 07/03/2014, 01:20

... crosstalk between auxin and other plant hormones [21–24] Our study also shows that genes involved in cytokinin (e.g cytokinin-Oglucosyltransferase, cytokinin dehydrogenase, and response regulators), ... Transcript proﬁling of auxin-responsive genes M Jain and J P Khurana responses, which indicates crosstalk between stress and auxin signaling In the recent past, the identiﬁcation of F-box proteins (TIR1 ... results reported in this study will be helpful in understanding the transcriptional network regulated by auxin and functional validation of selected auxin-responsive genes involved in developmental...

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Economic growth and atmospheric pollution in Spain: discussing the environmental Kuznets curve hypothesis potx

Ngày tải lên : 15/03/2014, 16:20

... and environment in each individual case In fact, there is growing interest in longitudinal analysis, as in the aforementioned study of CO2 emissions in several countries (Unruh and Moomaw, 1998), ... (1992), Panayotou (1993), Selden and Song (1994), and Holtz-Eakin and Selden (1995) Special issues of Ecological Economics (1995, 1998) and Environment and Development Economics (1996) have discussed ... support the EKC generally find inversion points in the relationship between economy and environment that are a very long way from current income in the developing countries This indicates that much...

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Economic Development and the Escape from High Mortality pdf

Ngày tải lên : 17/03/2014, 08:20

... movements in heights and the parallel changes in life expectancy Baten (2002) shows that colder winters beginning in the late 1750s lowered grain and protein production, leading to reductions in physical ... links mor¨ tality crises to human capital accumulation and early economic growth He correctly points out that crises receded in continental Europe and Scandinavia much after than in England and ... aggregate income gains were the dominating factor in explaining mortality decline during 1960s–70s (Preston, 1985) Similar quantitative eﬀects were found by Pritchett and Summers (1996) and Easterly...

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Department of Reproductive Health and Research including the UNDP/UNFPA/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP) doc

Ngày tải lên : 23/03/2014, 06:20

... worked in reducing maternal mortality include those relating to innovative financing measures; investment in human resources, both in terms of strengthening pre-service education and emphasizing in- service ... NGOs and other institutions Improving maternal and perinatal health working in the field on maternal and infant health Work with Doctors with Africa CUAMM, an NGO operating in Africa since 1955 in ... Hypertension in Pregnancy (ISSHP), in Geneva WHO will be leading and coordinating a number of sessions in both Congresses increasing visibility and repositioning HRP's work and priorities in the global...

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Three essays on economic reform and household behavior in contemporary China

Ngày tải lên : 03/06/2014, 02:20

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Financial Audit of the Department of Business, Economic Development and Tourism_part1 docx

Ngày tải lên : 18/06/2014, 20:20

... widespread dissemination of information on business, investment, and economic opportunities and conditions in the State The Hawaii Tourism Office has been inactive since July 1, 1998 and was abolished ... function, and its authority is limited to reviewing, evaluating, and reporting on its findings and recommendations to the Legislature and the Governor THE AUDITOR STATE OF HAWAII Kekuanao‘a Building ... the following types of examinations: Financial audits attest to the fairness of the financial statements of agencies They examine the adequacy of the financial records and accounting and internal...

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Financial Audit of the Department of Business, Economic Development and Tourism_part2 potx

Ngày tải lên : 18/06/2014, 20:20

... licensing and permit information and referral; business advocacy; planning and coordination of programs and projects aimed at specific business sectors or economically-distressed areas, including ... recommendations on the financial accounting and internal control practices and procedures of the Department of Business, Economic Development and Tourism (department) Summary of Findings We found several ... written guidelines over loan origination, maintenance of loan files, loan payment processing, and monitoring of delinquent borrowers Formally documenting and enforcing established policies and procedures...

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