... concentration of an alkyl nitrite on the horizontal axis and peak area on the vertical axis. e concentration of the analyte in a specimen is calculated using the calibration curve.Assessment and some ... cyanide to inactivate it [1]. Alkyl nitrites also show a coronary artery-di-lating e ect, and had been, therefore, used for the treatment of angina pectoris many years ago [2] ; the pharmacological ... rats. J Pharm Sci 74:780–7 82 10) Kielbasa WB, Bauer JA, Fung HL (1999) Analysis of isobutyl nitrite inhalant in rat and human blood: application for pharmacokinetic investigations. J Chromatogr...
... construct a cali-bration curve for DAEMS consisting of peak area ratio of DAEMS to IS on the vertical axis and DAEMS concentration on the horizontal axis. A peak area ratio obtained from a test ... chromato-gram; (b) an EI mass spectrum of DAEMS; (c) a CI mass spectrum of DAEMS.⊡ Figure 2. 2 620 VX and its decomposition productsReagent and their preparationã A 10-mg aliquot of EMPA (Aldrich, ... electrospray and atmospheric pressure chemical ionization. J Chromatogr A 794 :23 3 24 4 12) Kostiainen R, Bruins AP, Hakkinen VMA (1993) Identification of degradation products of some chemical warfare...
... Fast Blue BB salt. Eisei Kagaku 25 : 321 – 326 6) Matsunaga T, Nagatomo H, Narimatsu S et al. (1993) Studies on identification of cannabis seeds. I: Qualitative and quantitative analysis of cannabinoids ... principal constituents by thin-layer and gas chromatographies. Chem Pharm Bull 16: 822 – 826 4) Yokoyama M, Okada Y, Suzuki K (19 92) Determination of cannabinoids in cannabis oil by capillary gas chroma-tography. ... value of ∆9-THC-11-oic acid in urine at 50 ng/mL by immunoassay and the identi able value of the acid by mass spectral measurements at 15 ng/mL.Cases of analysis [13]Case 1: A 22 -year-old...
... use can be mentioned. In a chronic opiate-dependent patient, several grams of an opiate do occasionally not cause death.Toxic and fatal concentrations 20 2 Morphine and its analoguesã 5 mM Ammonium ... its analogues 8) Matsubara K, Fukushima S, Akane A et al. (19 92) Increased urinary morphine, codeine and tetrahydropapavero-line in Parkinsonian patient undergoing L-3,4-dihydroxyphenylalanine ... recommendable for diagnosis of heroin use, because of its relatively long half-life in the body [4].For accurate diagnosis ofa cause of death in an opiate poisoning case, the ratio ofa free...
... (1996) A case of severe methemoglobinemia for a newborn baby caused by well water. Jpn J Pediatr 49:1661–1665 (in Japanese) 4) Saito T, Takeichi S, Osawa M et al. (20 00) A case of fatal methemoglobinemia ... (1987) Cyanosis in infants caused by nitrates in well water. JAMA 25 7 :27 88 27 92 12) Fan AM, Steinberg VE (1996) Health implications of nitrate and nitrite in drinking water: an update on methe-moglobinemia ... it causes cyanosis, headache, easy fatigability, respiratory and conciousness dis-turbances and nally death. e fatal methemoglobinemia is rare, but fatal ones a er ingestion of nitrate...
... mL/min.l) A majority of basic drugs is adsorbed to the cation exchanger phase, and a minor part is adsorbed to the non-polar phase. e latter part is desorbed and adsorbed again to the cation exchanger ... 4 .2 shows mass spectra of the authentic cocaine, EME and BE a er derivatization.Setting up of cuto values are very common in USA and Europe as apartof QC ( quality control) and QA ( quality ... obtain a clean mass spectrum; while at 20 0 ng/mL of BE in blood, a satisfactory mass spectrum can be obtained. For BE, Metabolic pathways of cocaine.⊡ Figure 4.4Toxic and fatal concentrations...
... horizontal axis and peak area ratio of pentazocine to IS in the vertical axis. e peak area ratio ofa test specimen is applied to the calibration curve to obtain its pentazocine concentration.Assessment ... dimethylsilicone stationary phase (in-termediately polar) can be used, regardless of manufacturers.b) Any type of GC/MS instruments, to which a capillary column can be attached, can be used.c) With a computer ... human plasma by high performance liquid chromatography. Pharmazie 46:464–465 8) Seno H, Kumazawa T, Ishii A et al. (20 00) Determination of pentazocine in human whole blood and urine by gas...
... is rapid and distinct visual hallucination takes place 45 min–1 h a er oral intake of about 20 àg of LSD [1]. e hallucination becomes most marked 2 3 h a er the intake and lasts for 8– 12 h.In ... Albert Hofmann who did synthesize the compound; the pharmaco-logical activity can be obtained by oral administration of as small as 20 75 àg of LSD. e ab-sorption of LSD from the digestive tract ... powerful hallucinogenic drugs of abuse. LSD was explosively abused in U.S .A. in the latter half of the 1960s. In Japan, the amount of seizure of LSD is much smaller than that of methamphetamine....
... 467 :22 7 23 5 24 ) Tsuchihashi H, Nakajima K, Nishikawa M et al. (1991) Determination of methamphetamine and amphetamine in urine by headspace gas chromatography/mass spectrometry. Anal Sci 7:19 22 ... dis-seminated intravascular coagulation and death [19, 20 ]. A detailed review by Kalant [16] re-vealed that 87 MDAs-related fatalities were associated with hyperpyrexia, rhabdomyolysis, in-travascular ... readily absorbed from the intestinal tract and reaches its peak concentration in plasma about 2 h a er oral administration [21 , 22 ]. e doses of 50, 75 and 125 mg in the usual “recreational”...
... Figure 8 .2 Poisoning case, and toxic and fatal concentrations A 28 -year-old white man [24 ], who had had ahistoryof drug abuse, exhibited bizarre behav-ior on an airline ight; he was transferred ... (20 01) Analysis of urine samples in cases of alleged sexual assault: case history. In: Salamore SJ (ed) Benzodiazepines and GHB: Detection and Pharmacology. Humana Press, Totowa, pp 127 –144 ... MA, Miller ML et al. (20 00) Analysis of biofluids for gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL) by headspace GC-FID and GC-MS. J Anal Toxicol 24 : 421 – 428 17) Couper FJ, Logan...