aβ1 42 monomer and soluble oligomers
báo cáo hóa học: " A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells" pot
... (Panels A and C) or astrocytes (Panels B and C) were untreated (0) or infected with HSV-1 (MOI of 0.1, and 10) or MHV-68 (MOI of and 10) At 24 hours post-infection expression of DAI (Panels A and B), ... 37% and 70% Percoll solutions and centrifuged at 600 × G for 20 minutes at room temperature Glial cells were then collected from the interface and washed with PBS Microglia/ macrophages and astrocytes ... presence of DAI, STING, RIP3, and viral gG1 by immunoblot analysis In vitro stimulation of microglia and astrocytes with the DAI ligand, B-DNA Poly(dA:dT) double-stranded B-DNA (InvivoGen, San...
- 12
- 529
- 0
Báo cáo toán học: " Synthesis and anti-HSV-1 evaluation of new " docx
... with diluted hydrochloric acid (1:3), and the precipitate was filtered and recrystallized from DMF and water A mixture of the acids 3a–k and 4a–c (1 mmol), and phosphorus oxychloride (5 mL) was ... 3-(3,5Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and related 2-urea derivatives are potent and selective inhibitors of the FGF receptor-1 tyrosine kinase J Med Chem 43 :420 0 421 1 19 Vanlaer S, Voet A, Gielens ... 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridines (1a–k) and 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6-naphthyridine (2a–c) were synthesized and some of them were potent anti-HSV-1 agents The compounds 1d, 1f, 1g, and 1h exhibited the...
- 24
- 433
- 0
Báo cáo khoa học: A (1fi3)-b-D-glucan recognition protein from the sponge Suberites domuncula Mediated activation of fibrinogen-like protein and epidermal growth factor gene expression pot
... AB024737.1 and TECL5B_TACTR; AB024738.1) (iii) Angiopoietin: angiopoietin and precursors from mouse (AGP1_MOUSE; O08538 and AGP2_MOUSE; O35608), bovine (AGP1_BOVIN; O18920 and AGP2_BOVIN; O77802), and ... lipopolysaccharide (LPS, lane d), for h, and then washed and probed with biotin-curdlan (cur), as described in the Materials and methods (1fi3)-b-D-glucan-binding proteins and was therefore termed GLUBPp_SUBDO ... encoding a fibrinogen-like protein, and also one for a cytokine, are strongly expressed Materials and methods Chemicals and enzymes The sources of chemicals and enzymes used were as given previously...
- 14
- 299
- 0
Báo cáo Y học: Cloning and characterization of the mammalian-specific nicolin 1 gene (NICN1) encoding a nuclear 24 kDa protein doc
... amino acids and has a calculated molecular weight of 24 kDa (Fig 1) The amino acid sequences of the NICN1 proteins are 94% identical between human and dog, and 89% identical between human and mouse ... NaCl/Pi) and three times with washing buffer B (500 mM NaCl, 10 mM EDTA, 0.5% Triton X-100 in 125 mM Tris/HCl pH 8.0) prior to analysis of the samples by SDS/PAGE and phosphorimaging Ó FEBS 2002 5 242 ... excitation line of an argon laser and an emission range between 505 and 525 nm for fluorescence detection as described previously [9] The genomic DNA sequences of the canine and murine NICN1 genes were...
- 6
- 450
- 0
báo cáo khoa học: "Bilateral adrenocortical carcinoma in a patient with multiple endocrine neoplasia type 1 (MEN1) and a novel mutation in the MEN1 gene" potx
... ultrasound and Tc99 m Sestamibi-scans both disclosing hyperplasia of the parathyroid glands, abdominal MRI scan and endoscopic ultrasound (EUS) both disclosing a 4.5 × 3.0 cm tumor in the body and tail ... lesion and distal pancreatectomy and splenectomy were performed The incidence of pituitary adenomas in MEN1 patients varies between 10 and 60% [13], while their symptoms depend on the type and the ... (amino acids 1-40) and midregion (amino acids 323 -428 ) of Menin and requires the N-terminus of JunD (amino acids 8-70) Menin’s tumor suppressor involves direct binding to JunD and inhibition of...
- 7
- 412
- 0
Báo cáo y học: "Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells" pot
... LPS and IFN for 24 h Cycloheximide (90 μg/ml) was added, and cell extracts were collected at the indicated times and western blotted for COX-2 and α-tubulin A, Representative images of COX-2 and ... primary and secondary stimuli that may be present, and by cellular factors, such as supply of arachidonic acid, complement of various prostaglandin synthases, and expression of prostaglandin receptors ... NO increases prostaglandin synthesis [40], and S-nitrosylation of COX-2 activates the enzyme and contributes to cell injury [41 ,42] The impact of the co-induction of iNOS and COX-2 in endothelium...
- 9
- 457
- 0
Báo cáo y học: "Egress of HSV-1 capsid requires the interaction of VP26 and a cellular tetraspanin membrane protein" doc
... of the study, and participated in its design and coordination, QL and LL revised the manuscript LW and LL participated in the design of the study and performed analysis, LW, CD and YZ participated ... cell transfected and infected were harvested and extracted for further real-time PCR The protocol is described in Material and Method a Viral loads shown with the copy of α-4, tk and gC genes of ... 219, ATCC) and Hela cells were grown in Dulbecco's Modified Eagle's Medium (DMEM) (Gibco, Grand Island, NY, USA) supplemented with 50 mmol/L L-glutamine (Sigma, St Louis, MO, USA) and 10% (v/v)...
- 12
- 302
- 0
Báo cáo khoa học:" A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages" docx
... and then harvested cells at 0, 4, 12, 24, and 48 hr postinfection Total RNA was isolated as described in Materials and Methods, and various viral mRNA levels were quantitated by RT-PCR ICP0 and ... 122), anti-Annexin-PE, and 7-ADD from BD PharMingen (San Diego, CA) and Biolegend (San Diego, CA) and then analyzed by FACS as we previously described [35] Confocal Microscopy and Image Analysis ... monolayers of DCs and RS cells were infected with 10 or PFU per cell of McKrae and the virus yield determined at the indicated times by standard plaque assays as described in Materials and Methods...
- 13
- 266
- 0
Báo cáo khoa học: " A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages" pps
... and then harvested cells at 0, 4, 12, 24, and 48 hr postinfection Total RNA was isolated as described in Materials and Methods, and various viral mRNA levels were quantitated by RT-PCR ICP0 and ... 122), anti-Annexin-PE, and 7-ADD from BD PharMingen (San Diego, CA) and Biolegend (San Diego, CA) and then analyzed by FACS as we previously described [35] Confocal Microscopy and Image Analysis ... monolayers of DCs and RS cells were infected with 10 or PFU per cell of McKrae and the virus yield determined at the indicated times by standard plaque assays as described in Materials and Methods...
- 13
- 468
- 0
Đại số 10 ban A từ tiết (1-21)
... * GV yêu cầu HS làm câu hỏi sau: - cho kết điều tra dân số tỉnh A là: 137 9425 ngời 500 ngời 137 9425 ngời 600 ngời; 137 9425 ngời 700 ngời * GV nêu dạng chuẩn số gần trờng hợp số gần số nguyên số ... 41: A B = (0,4); A B = [1,2] suy : CR(A B) = ( ;0] [ 4; + ) CR(A B) = ( ;1) ( 2; + ) * Bài 42: Ta có A ( B C ) = { a, b, c} ; ( A B ) ( A C ) = { a, b, c} ; ( A B ) C = { b, c, e} ... 43,96(cm) thờng nhận đợc số gần - lấy = 3,14 ta đợc: * Gv : VD trên, số L = R giá trị L =2.7.3, 142 = 43,988(cm) chu vi đờng tròn, giá trị: L 43,96 ; L 43,988 biểu thị sai lệch phép tính chu...
- 46
- 407
- 0
KỲ KSCL THI ĐẠI HỌC NĂM HỌC 20122013 LẦN 1 ĐỀ THI MÔN TOÁN KHỐI A, A1 SỞ GD&ĐT VĨNH PHÚC
... Tiptheotaxộtcỏcscúdng 0bcde vi2chschnv2chslphõnbit. Khiútachnra2chschn(khỏc0)v2chslrihoỏnvvocỏcvtrớb,c, d,e Tacú C42 C2.4! 0.25 2 Tútacúscỏcscntỡml: C5 C52 5!- C4 C5.4! =10560 s. 0.25 ưưưưưưưưưưHtưưưưưưưưưư ...
- 7
- 1,268
- 33
Tài liệu A resource for reading and words part 1 ppt
... own self esteem and creates the right kind of impression I have always the kindness of my friends We have to find a way to our fifty thousand members as an educational and propaganda machine Music, ... Christmas is only a few days away and the two children in the Robinson family feel very excited and are impatient for it Their mother has baked them a very large and delicious Christmas cake She ... people crowded in and the reality began to fully sink in, I felt I couldn't breathe I stepped out on the porch, and the sight beyond the gates was incredible; tens of thousands of people gathered...
- 15
- 706
- 3
Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt
... (2 Mn), radical-containing R2F monomers and apoprotein free of both The manganese and radical content per mol R2F monomer found in the present study (0.74 and 0.18, respectively) suggest that only ... pitch standard (g = 2.0028) A solution of 10 mm CuSO4 in m NaClO4 and 10 mm HCl was used as the standard for spin integration Further EPR conditions are provided in the legend to Fig Q-band EPR ... Microbiology (Pandalai SG ed), pp 15–39 Research Signpost, Trivandrum, India 18 Teshiba S (1989) Production of Nucleotides and Nucleosides by Fermentation, Vol 3, 1st edn Gordon and Breach Science...
- 14
- 872
- 0
Tài liệu Báo cáo khoa học: Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-1b-treated rat smooth muscle cells by n-6 and n-3 polyunsaturated fatty acids pdf
... action of EPA and DHA (Eur J Biochem 271) 4471 Fig Effect of n-3 and n-6 polyunsaturated fatty acid (PUFA) supplementation on caveolin-1 and caveolin-3 expression and their impact on p42/44 mitogen-actived ... the first-strand cDNA and 300 nM primers Amplification was performed on an iCycler (Bio-Rad), according to the manufacturer’s instructions, and cycle parameters were: 50 °C (2 min) and 95 °C (10 ... with the )973 bp cyclin D1 gene promoter and either the dominant-positive or the dominant-negative Ras and Raf mutants, and the effects of incorporated n-6 and n-3 PUFAs were explored in cells treated...
- 12
- 499
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008