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autophagy—autolysosomal response and secretory activity in the irradiated mscs subjected to bacterial challenge

Báo cáo y học:

Báo cáo y học: "Enhanced glutamate, IP3 and cAMP activity in the cerebral cortex of Unilateral 6-hydroxydopamine induced Parkinson’s rats: Effect of 5-HT, GABA and bone marrow cell supplementation" ppsx

Báo cáo khoa học

... acid) was infused into the right Substantia nigra Pars compacta (SNpc) at a flow rate of 0.2 μl/min After stopping the infusion of the toxin, the probe was kept in the same position for a further ... glycine and 100 μM glutamate Specific [ H] MK-801 binding was obtained by subtracting nonspecific binding in the presence of 100 μM unlabeled MK-801 from the total binding Protein Determination ... by linear regression analysis by plotting the specific binding of the radioligand on the X-axis and bound/free on the Y-axis The maximal binding is a measure of the total number of receptors...
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Báo cáo y học:

Báo cáo y học: "Development of daily rhythmicity in heart rate and locomotor activity in the human fetus" ppt

Báo cáo khoa học

... done according to the following parameters: hourly fluctuations in maternal and fetal HR, intra-minute fluctuation of HR, and baseline rhythm The baseline was defined as the level obtained at a.m., ... ± 1.03 min, corresponding to 28% of the total recording time from a.m to a.m and from p.m to p.m The locomotor activity of these fetuses was 3.5 fold higher in "active" hours than that in "quiet" ... in the levels of fetal physiological functions bears a biphasic character; the levels are reduced in the morning (4 a.m to a.m.) and in the afternoon (2 p.m to p.m.) and increased during the...
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Báo cáo y học:

Báo cáo y học: "Evaluation of the effects of a VEGFR-2 inhibitor compound on alanine aminotransferase gene expression and enzymatic activity in the rat liver" pdf

Báo cáo khoa học

... of drugs and toxins may help in understanding the potential localization of hepatic diseases and carcinomas within the liver Understanding these regional effects is critical in the interpretation ... both toxins is differential in nature The distributional effect of copper, for example is thought to reflect the site of gastrointestinal absorption and portal streamlining into the liver [14] Other ... transferred to liquid nitrogen for freezing The remaining tissues were fixed in 10% neutral buffered formalin and submitted to histology for processing and staining with H&E, caspase and TUNEL...
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Báo cáo khoa học:

Báo cáo khoa học: "Luminal concentrations of L- and D-lactate in the rectum may relate to severity of disease and outcome in septic patients" ppt

Báo cáo khoa học

... between them and their relation to clinical parameters Therefore, the present study was undertaken to assess concentrations of L- and Dlactate in the rectal lumen and systemic circulation in septic ... disturbances in critically ill patients [9,10] To advance our understanding of these potential markers of intestinal metabolism in sepsis, several questions have to be answered, including both the correlation ... 0.05 compared with baseline values in survivors cNine patients in the non-surviving group and seven in the surviving group received noradrenaline dValues from ABL blood gas autoanalyser (Radiometer,...
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Báo cáo khoa học:

Báo cáo khoa học: "Leaf gas exchange and carbohydrate concentrations in Pinus pinaster plants subjected to elevated CO 2 and a soil drying cycle" doc

Báo cáo khoa học

... of stomata to MATERIALS AND METHODS growing conditions In March 1994, seeds of Pinus pinaster Ait., provenance Landes (southwest France), were individually germinated in L cylindrical containers ... showed that increasing the atmosincreased the CO assimilation rate and needle starch concentration all along the soil drying cycle in P pinaster However, in this drought-avoiding In conclusion, ... two-fold increase of pinitol in fine roots of P pinaster seedlings grown in mineral solution, as it was also mentioned by Popp and Smirnoff [ 14] in Cajanus cajan Can results obtained in such conditions...
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Báo cáo khoa học: Structural and functional aspects of unique type IV secretory components in the Helicobacter pylori cag-pathogenicity island potx

Báo cáo khoa học: Structural and functional aspects of unique type IV secretory components in the Helicobacter pylori cag-pathogenicity island potx

Báo cáo khoa học

... factor-jB and the induction of pro -in ammatory production of cytokines, mainly interleukin (IL)-8 [12] The activation of a pro -in ammatory signalling cascade has been confirmed to be Nod1 cytoplasmic ... involving a-helix A, the nearby loop, the first and last turns of helices E and F, and the C-terminus helices I and J In addition, there is a lysine-rich N- and C-terminus, in accordance with the ... findings may indicate that CagD is released into the supernatant during host cell infection by an unknown independent mechanism and then binds to the host cell surface or is incorporated in the...
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Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

Báo cáo khoa học

... (a) the main driving force for the folding is the unfavourable interaction between the osmolyte and the peptide backbone, and (b) the total contribution of side chains to the stability of the ... references therein] The binding model claims that an increase in the osmolyte-induced stability arises from the preferential hydration (or exclusion of the osmolyte) leading to a shift in the denaturation ... [21–25], and DGD° values in the presence of these osmolytes are given in Table However, DGD° values of RNase-A in the presence of alanine, serine, lysine, b-alanine, taurine and dimethylglycine have...
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Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf

Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf

Báo cáo khoa học

... processes In this study we examined the role of Bcp2 in order to increase the knowledge of the enzymatic activity involved in the oxidative stress in S solfataricus To detect differences in the response ... thioredoxin) In typical 2-Cys, Sp at the N terminus and SR at the C terminus belong to different subunits and condense to form an intersubunit disulfide bond; in atypical 2-Cys, Sp at the N terminus and ... Furthermore, we report the cloning, the expression and the characterization of the recombinant protein rBcp2 in order to shed light on its role in the detoxification process and on its catalytic...
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Strengthening the Education Sector Response to School Health, Nutrition and HIV/AIDS in the Caribbean Region: A Rapid Survey of 13 Countries pdf

Strengthening the Education Sector Response to School Health, Nutrition and HIV/AIDS in the Caribbean Region: A Rapid Survey of 13 Countries pdf

Sức khỏe giới tính

... sector in participating countries to monitor their progress against the core set of actions to strengthen national SHN and HIV responses by the education sector, as outlined in the Port-of Spain ... central to the education sector response to the epidemic Later, in an effort to strengthen and harmonize education sector responses to HIV across the region, the Caribbean Ministers of Education and ... Nevis, St Lucia, and Trinidad and Tobago, lack an HIV section in the MoE but have a designated HIV/AIDS coordinator The HIV/AIDS coordinator in Trinidad and Tobago is attached to the Student Support...
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Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt

Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt

Báo cáo khoa học

... will also be of interest to examine whether additional proteins bind to the other three MREs in the WD promoter, and if so, to determine the precise mechanisms by which such proteins modulate WD ... another band of 82 kDa when the MREa-protein band from the EMSA was excised from the native gel and resolved by SDS/PAGE (unpublished data) We purified the MREa-binding proteins using the avidin–biotin ... difluoride membrane, and the individual proteins were subjected to N-terminal sequencing The N-terminus of the 70-kDa protein was blocked by modification Therefore, the protein was digested with...
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2009 Investment Company Fact Book 49th edition - A Review of Trends and Activity in the Investment Company Industry pptx

2009 Investment Company Fact Book 49th edition - A Review of Trends and Activity in the Investment Company Industry pptx

Quỹ đầu tư

... effect on funds invested in foreign stocks U.S stock and bond funds holding international assets decreased further from the strengthening of the U.S dollar and the resulting decrease in the dollar ... geared toward institutional investors attracted $525 billion in new cash during 2008 Increased economic uncertainty during the year and ongoing turmoil in the money markets encouraged these investors ... drop in their financial and housing assets since the crisis started As homeowners and investors survey the damage, they are left to wonder when it will end and how the eventual rebuilding of their...
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Báo cáo khoa học: Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells pot

Báo cáo khoa học: Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells pot

Báo cáo khoa học

... E2F-1-dependent and involves an increase in expression of the mitotic regulator, pRb In addition, IxoA was shown for the first time to induce apoptosis in SW480 human colon cancer cells To investigate the ... chemopreventive agents, including resveratrol [26,27], brassinin [28,29], and deguelin [30,31] Resveratrol is present in grapes, red wine and peanuts, brassinin is from Chinese cabbage, and deguelin is from ... shown to have a critical role in initiating the apoptotic program by antagonizing the function of the antiapoptotic BCL-2 and activating BAX and BAK [24] Therefore, the expression of BIM ⁄ BOD...
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2011 Investment Company Fact Book - A Review of Trends and Activity in the Investment Company Industry doc

2011 Investment Company Fact Book - A Review of Trends and Activity in the Investment Company Industry doc

Quỹ đầu tư

... started to retire, and because investors’ willingness to take investment risk tends to decline as they age (Figure 2.5), it is natural for them to allocate their investments increasingly toward ... households in 1998 The aging of the population also likely has played a role in reducing demand for equity funds As investors grow older, their willingness to take investment risk tends to decline In ... Stock funds dominated fund investing following the passage of the Investment Company Act of 1940 But successive bear markets in stocks in the 1970s along with rising interest rates drew investors...
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báo cáo hóa học:

báo cáo hóa học:" The influence of the level of physical activity and human development in the quality of life in survivors of stroke" potx

Hóa học - Dầu khí

... Thus, the closer the observed value is to the minimum value, the smaller is the numerator and therefore the worse the situation of development Conversely, the closer the observed value is to the ... having suffered a stroke at least one year prior to the study and showing sequelae, hemiplegia or hemiparesis The individuals were classified according to the Rankin Scale [10,11], and in the ... value, the better the situation in terms of development The maximum and minimum values are defined through the observation of the world tendencies in terms of indicators for the long term, allowing...
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Báo cáo khoa học

Báo cáo khoa học " Cordyceps militaris polysaccharides can enhance the immunity and antioxidation activity in immunosuppressed mice " pptx

Báo cáo khoa học

... was administered via intraperitoneal injection The others were administered via gavage in 0.2 ml solutions Twenty-four hours after the last drug administration, the animals were weighed and then ... on the activity of MDA in the different organs of the immunosuppressed mice Fig shows the significant increases in MDA levels (P < 0.01) in the hearts, livers and kidneys of the CY-treated and ... investigated The results indicate that CMP can reverse the CY-induced atrophy of immune organs In line with the usage of Cordyceps in China, Chinese medicines are strongly recommended for the ageing population...
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Báo cáo lâm nghiệp:

Báo cáo lâm nghiệp:"Growth and biomass partitioning of Fagus sylvatica L. and Quercus robur L. seedlings in response to shading and small changes in the R/FR-ratio of radiation" pot

Báo cáo khoa học

... respectively)) and the dry mass of the main stem (DMshoot) at the end of the experiment, the dry mass of the main stem at the start of the experiment and after 50 days was estimated using the following ... Z2 for RHG and RGDS in the second part of the growing period as well as in the total period indicates that the difference between the control and the shade treatments in height growth and stem ... material The seeds were sown into a permeable pot of 2000 cm3 in size and the seedlings stayed there to the end of the experiment The rooting substrate consisted of a mixture of peat and agriperl...
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Báo cáo y học:

Báo cáo y học: "Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF-1 in cultured rat nucleus pulposus cells" ppsx

Báo cáo khoa học

... through G1 into S phase requires cyclin D-CDK4/6 and cyclin E-CDK2, which phosphorylate the retinoblastoma protein [26] CDK inhibitors (CKIs) are the negative regulators and are grouped into two ... TGF1 [29-32] The aim of the present study was therefore to reveal the role of c-Myc in mitogenic response to TGF1 in nucleus pulposus cells The study was designed to (1) analyze the effect of ... proliferation and the cell cycle progression in nucleus pulposus cells, (2) determine if c-Myc transcription inhibitor obstructed the effect of TGF1, and (3) determine the role of ERK1/2 in stabilizing the...
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Báo cáo y học:

Báo cáo y học: "Markers of B-lymphocyte activation are elevated in patients with early rheumatoid arthritis and correlated with disease activity in the ESPOIR cohort" pdf

Báo cáo khoa học

... with UA, and controls The chi-square test was also used to compare the proportion of anti-CCP between RA patients and UA patients and, within the RA group, to compare the proportion of RF and anti-CCP ... beta2-microglobulin, and kappa and lambda FLCs of immunoglobulins) or, in RA, with the presence of initial erosions (IgM-RF, IgA-RF, antiCCP, ESR, IgA, and kappa FLCs of immunoglobulins) were included in multivariate ... activating factor of the tumor necrosis factor family (BAFF) values are expressed in nanograms per milliliter, total immunoglobulin values in grams per liter, and free light chain of immunoglobulins...
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