assuming a leadership role

Báo cáo y học: " Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis"

Báo cáo y học: " Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis"

Ngày tải lên : 03/11/2012, 10:52
... Zhao Z, Lange DJ, Voustianiouk A, Macgrogan D, Ho L, Suh J, Humala N, Thiyagarajan M, Wang J, Pasinetti GM. A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral ... incubation with a reporter antibody (HRP–conjugated anti–rabbit IgG, Santa Cruz Biotech, CA). The assay was developed using a stabilized HRP substrate. All samples were analyzed in the linear ... by ALS grant from the Department of Veterans Affairs, NCCAM 5R21 AT002602-02 and NCCAM 1R21 AT003632-0 1A1 to GMP and NARSAD and DK071308 to SRS. Conflict of interest The authors have declared...
  • 8
  • 499
  • 0
Tài liệu Báo cáo khoa học: The most C-terminal tri-glycine segment within the polyglycine stretch of the pea Toc75 transit peptide plays a critical role for targeting the protein to the chloroplast outer envelope membrane ppt

Tài liệu Báo cáo khoa học: The most C-terminal tri-glycine segment within the polyglycine stretch of the pea Toc75 transit peptide plays a critical role for targeting the protein to the chloroplast outer envelope membrane ppt

Ngày tải lên : 19/02/2014, 07:20
... *SA*AAAAA* AGG AAA******* GAG ****AAA*** GGA *******AAA GAA ****AAAAAA AGA AAA****AAA AAG AAA*AAA*** GGD *******DDD GGE *******EEE GGL *******LLL GGN *******NNN GGS *******SSS GGP *******PPP A. J. Baldwin ... FEBS tion apparatus, faces the stromal compartment. J Biol Chem 273, 16583–16588. 21 Gunasekaran K, Nagarajaram HA, Ramakrishnan C & Balaram P (1998) Stereochemical punctuation marks in protein ... translocation intermediates trapped in the Table 1. Part of the pea Toc75 transit peptide and its derivatives used in this study. Name Sequence (residues 91–100) WT GGGAGGGGGG polyAla *SA*AAAAA* AGG...
  • 9
  • 496
  • 0
Tài liệu Báo cáo khoa học: A possible role of mitochondria in the apoptotic-like programmed nuclear death of Tetrahymena thermophila Takashi Kobayashi and Hiroshi Endoh docx

Tài liệu Báo cáo khoa học: A possible role of mitochondria in the apoptotic-like programmed nuclear death of Tetrahymena thermophila Takashi Kobayashi and Hiroshi Endoh docx

Ngày tải lên : 20/02/2014, 03:20
... Kobayashi and H. Endoh 5380 FEBS Journal 272 (2005) 5378–5387 ª 2005 FEBS rial large subunit rRNA (mtLSUrRNA) gene: mtLSU-3, 5¢- TACAACAGATAGGGACCAA-3¢; and mtLSU-4, 5¢- CCTCCTAAAAAGTAACGG-3¢. ... & Vaux DL (2000) Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 102, 43–53. 7 Suzuki Y, Imai Y, Nakayama H, Takahashi ... apoptotic nucleus [29,30]. The large- fragment-size DNA fragmentation and DNA laddering are characteristics of the apoptotic nucleus, and the final DNA degradation step in the autophagosome may correspond...
  • 10
  • 642
  • 0
Báo cáo khoa học: Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1 pot

Báo cáo khoa học: Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1 pot

Ngày tải lên : 06/03/2014, 22:21
... localization at the membrane–solute interface. There was no alteration in the extent of labelling by BM in any conformational state examined. In contrast, there was a dramatic reduction in labelling ... undergo topographical alterations dur- ing conformational changes of ABCB1. In a recent study, we demonstrated, using a similar approach, that the mutation of several residues within TM12 also influ- ences ... basal and ATP-bound states of the model, and that this section of TM12 appeared to act as an anchor around which the rest of the helix moved. Second, the model shows that the intracellular part...
  • 12
  • 380
  • 0
Báo cáo khoa học: Trigger factor interacts with the signal peptide of nascent Tat substrates but does not play a critical role in Tat-mediated export pptx

Báo cáo khoa học: Trigger factor interacts with the signal peptide of nascent Tat substrates but does not play a critical role in Tat-mediated export pptx

Ngày tải lên : 07/03/2014, 16:20
... (5¢-ACGC GGATCCAG TCATAAACAGCGGTTGC-3¢, Bam HI site un derlined), 87SufI-BamHI-rv (5 ¢-ACGC GGATCCAACATCGTCGC CCTTCCA-3¢, BamHI site underlined) and SufIHA- XbaI+ClaI-rv (5¢-ACTG ATCGATCTAGATTACGCAT AGTCAGGAACATCGTATGGGTAGCCGCCTGGCG GTACCGGATTGACCAAC- ... a s a template and the primers RRTorA-SacI-fw (5¢-GCGCG GAGCTCAAGAAGGA AGAAAAATAATGAAC-3¢, SacI site underlined) and TorA/Lep2-BamHI-rv (5¢-GCAT GGATCCCGCGCGC TTGATGTAATC-3¢, BamHI site underlined). ... 5B, lane 10). Similarly, steady state analysis did not A B Fig. 4. In vivo analysis of S ufI export in Dtig, DdnaKdnaJ and Dtig DdnaKdnaJ mu tants. S teady state (A) and pulse-chase (B) analysis...
  • 9
  • 393
  • 0
The Carbon and Global Warming Potential Impacts of Organic Farming: Does It Have a Significant Role in an Energy Constrained World? pptx

The Carbon and Global Warming Potential Impacts of Organic Farming: Does It Have a Significant Role in an Energy Constrained World? pptx

Ngày tải lên : 08/03/2014, 23:20
... survey, namely the Organic Agriculture Centre of Canada, the Organic Value Chain Roundtable and Agriculture and Agri-Food Canada. References and Notes 1. Canning, P.; Charles, C .A. ; Huang, S.; ... efficiencies, an aspect that requires more study. Finally, reducing transport offers some additional, if smaller, potential for E and GHG gains (and again data for the Canadian food system is lacking) and ... significantly by crop rotation. Khakbazan et al. [101] reported from Manitoba on a comparison of 16 alternative management practices for a wheat-field pea rotation for economic returns, non-renewable...
  • 41
  • 524
  • 1
Báo cáo " Cell suspension culture Panax ginseng C. A. Meyer: Role of plant growth regulators and medium composition on biomass and ginsenoside production " docx

Báo cáo " Cell suspension culture Panax ginseng C. A. Meyer: Role of plant growth regulators and medium composition on biomass and ginsenoside production " docx

Ngày tải lên : 14/03/2014, 10:20
... C .A. Meyer) which belong to the Araliaceae, is one of the most variable oriental herbs. It has been used as a healing drug and health tonic in countries as Korea, China and Japan since ancient ... was obtained in medium containing 2,4-D as compared to IBA or NAA. However, ginsenoside production was much higher in IBA or NAA containing medium and 7 mg/L IBA was determined to be optimal ... Determination and analyses Extraction and determination of ginsenoside production were determined as reported previously [9]. Experimental design and data analysis All experiment were repeated...
  • 6
  • 492
  • 0
International Labor Migration: A Responsible Role for Business pdf

International Labor Migration: A Responsible Role for Business pdf

Ngày tải lên : 15/03/2014, 21:20
... applications available in villages and towns »  Make the passport and visa application process more straightforward 5 ‘‘ A widespread tendency is to regard migrants as a complementary labor force, and ... create management training programs to improve the sustainability of the company’s recent policy changes around migrant workers. Tenaganita has also created and implemented awareness and training ... the Taskforce is conducting formal national consultations with govern- ments in Brunei Darussalam, Cambodia, Lao PDR, Malaysia and Singapore. » ILO International Migration Program (MIGRANT):...
  • 64
  • 252
  • 0
Báo cáo khoa học: A novel gene, fad49, plays a crucial role in the immediate early stage of adipocyte differentiation via involvement in mitotic clonal expansion docx

Báo cáo khoa học: A novel gene, fad49, plays a crucial role in the immediate early stage of adipocyte differentiation via involvement in mitotic clonal expansion docx

Ngày tải lên : 16/03/2014, 04:20
... c (PPARc) and CCAAT ⁄ enhancer-binding protein a (C ⁄ EBPa) play important roles as master regulators [12]. In terminal differentiation, PPARc and C⁄ EBPa transactivate each other and upregulate ... (5¢-TTTCTCGATCACCTCGAC-3¢). In the same way, the 3¢ region of the human cDNA of fad49 was amplified with a human fad49-specific forward primer (5¢-ACATGACCATTCCTCGAG-3¢) and reverse primer (5¢-TCTAGGCAGAAAGGGAGT-3¢). ... fad49 cDNAs have been deposited in the GenBank database with accession numbers AB430861 and AB430862, respectively. Acknowledgements We thank Asako Shimada and Aya Fujii for technical assistance (Nagoya...
  • 13
  • 385
  • 0
Báo cáo khoa học: Peroxisome proliferator-activated receptor a plays a vital role in inducing a detoxification system against plant compounds with crosstalk with other xenobiotic nuclear receptors docx

Báo cáo khoa học: Peroxisome proliferator-activated receptor a plays a vital role in inducing a detoxification system against plant compounds with crosstalk with other xenobiotic nuclear receptors docx

Ngày tải lên : 16/03/2014, 14:20
... 5¢-CCAGCTCTGCTTCAT TCCTCTCT-3¢ and 5¢-CGCAGGAATGGATAAACATA AGCA-3¢ for Cyp2c38; 5¢-ACTTCTCTGTGGCAAGCCC TGTTG-3¢ and 5¢-TCCACTAGCACAGATCACAGATC ATGG-3¢ for Cyp2b9; 5¢-TGCAGAACTTCCACTTCAA ATCCA-3¢ and 5¢-AATTTCCCCCTTCTCTGGCTACC-3¢ for ... 5¢-AATTTCCCCCTTCTCTGGCTACC-3¢ for Cyp 2a5 ; 5¢-TTGTTCTAAAAGTTGTGCCACGG GATG-3¢ and 5¢-AGAGATGATCCCATGAGAAACGG TGAA-3¢ for Cyp 3a4 4; 5¢-AGATCATCATTCCTTGGCA CTGG-3¢ and 5¢- ATTGCAGAAAGGAGGGAAGATGG -3¢ for Cyp 4a1 0; ... 5¢-CCAGTTGAGTGACGAGGAG ATGG-3¢ and 5¢-TCTGCATGCCCTCAAATGTTACC-3¢ for Akr1b8; 5¢-ACCACTCTCTGGATGTGATTGGA-3¢ and 5¢- TCAAGAACATTTTATTTCCCACATTTT-3¢ for Ugt2b5; 5¢-ATTGCCCATATGGTGGCCAAAGGAG-3¢ and...
  • 9
  • 280
  • 0
Báo cáo khoa học: Kinetic studies and molecular modelling attribute a crucial role in the specificity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263 pdf

Báo cáo khoa học: Kinetic studies and molecular modelling attribute a crucial role in the specificity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263 pdf

Ngày tải lên : 16/03/2014, 16:20
... NIPPA, N-(5-nitro-2-pyridyl)-phenylacetamide; PhAc-pNA, phenylacetyl 4-nitroanilide; PhAc-pAB, 4-phenylacetamidobenzoic acid; PhAc-mAB, 3-phenylacetamidobenzoic acid; PhAc-oAB, 2-phenyl- acetamidobenzoic acid; PhAc-bNA, phenylacetyl ... 25, E-mail: nstambol@orgchm.bas.bg, kaneti@orgchm.bas.bg; http://www.orgchm.bas.bg/ Abbreviations: PA, penicillin acylase; PhAc, phenylacetyl moiety; 6APA, 6-aminopenicillanic acid; PG or PhAc-6APA, penicillin ... PhAc-pAB, PhAc-mAB, PhAc-oAB vs. phenylacetyl 4-nitroanilide (PhAc-pNA), NIPAB and iso-NIPAB, but it suggests an explanation of the 16-fold difference between the K m values of PhAc-MCA and PhAc-bNA...
  • 8
  • 438
  • 0
Báo cáo khoa học: "Brutus: A Semantic Role Labeling System Incorporating CCG, CFG, and Dependency Features" pot

Báo cáo khoa học: "Brutus: A Semantic Role Labeling System Incorporating CCG, CFG, and Dependency Features" pot

Ngày tải lên : 17/03/2014, 01:20
... Argument Mapping Model An innovation in our approach is to use a separate clas- sifier to predict an argument mapping feature. An ar- gument mapping is a mapping from the syntactic argu- ments of a verbal ... approach (and lexicalist approaches in general) is the ability to en- code verb-specific argument mappings. An argument mapping is a link between the CCG category and the semantic roles that are ... motivates our discussion of future research for computational se- mantics with CCG (Section 12). 2 Combinatory Categorial Grammar Combinatory Categorial Grammar (Steedman, 2000) is a grammatical...
  • 9
  • 282
  • 0
Mastering the Leadership Role in Project Management: Practices that Deliver Remarkable Results

Mastering the Leadership Role in Project Management: Practices that Deliver Remarkable Results

Ngày tải lên : 17/03/2014, 20:34
... 539–46. ptg7913109 xvi Mastering the Leadership roLe in projeCt ManageMent consultant to the UN in large organizational change projects in Par- aguay, South America. She teaches project management courses to graduate ... program manager of JASSM was given two major mandates. The first was not to repeat any of the mistakes of the past, meaning the TSSAM program. The Tri-Service Standoff Attack Missile (TSSAM) had ... Culture, Leadership, and Organizations: The GLOBE Study of 62 Societies. Thousand Oaks, CA: Sage Thousand Oaks. 20. The data for these cases was originally collected by Dora Cohenca-Zall, Edward...
  • 267
  • 413
  • 0
Báo cáo Y học: Mitochondrial DNA deletion mutations A causal role in sarcopenia docx

Báo cáo Y học: Mitochondrial DNA deletion mutations A causal role in sarcopenia docx

Ngày tải lên : 17/03/2014, 23:20
... human tissues. Proc. Natl Acad. Sci. USA 89, 7370–7374. 24. Katayama, M., Tanaka, M., Yamamoto, H., Ohbayashi, T., Nimura, Y. & Ozama, T. (1991) Deleted mitochondrial DNA ion the skeletal ... normal regions. LCM coupled with PCR analysis has clearly demonstrated that age-associated mtDNA deletion mutations are locali- zed to specific cells identified as abnormal by histo- chemical analysis. ... COX – /SDH normal phenotype. These data clearly demonstrate that ETS abnormalities have a localized physiological impact on the cell and can result in fiber atrophy. Subsequent longitudinal analysis of atrophied fibers...
  • 6
  • 315
  • 0
Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot

Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot

Ngày tải lên : 18/03/2014, 01:20
... 5¢-GTGTTACTT CTGCTCT-3¢; pSVL(antisense) 5¢-TCTAGTTGTGGTT TGT-3¢; C45 8A( sense) 5¢-ATACTTGAGTGGGCTGTG TTATCAG-3¢; C45 8A( antisense) 5¢-ATCTGATAACAC AGCCCACTCAAGTAT-3¢; C46 6A( sense) 5¢-GATAAA GCACCCGCTATCACAGACTGG-3¢; ... 5¢-GATAAA GCACCCGCTATCACAGACTGG-3¢; C46 6A( antisense) 5¢-CCAGTCTGTGATAGCGGGTGCTTTATCTG-3¢; C49 1A( sense) 5¢-GCAGAGAGCAAAGCCTATTTGAT AACAG-3¢ and C491(antisense) 5¢-TGTTATCAAATAG GCTTTGCTCTCTG-3¢. PCRs ... 4 and 6 of GCSFR using the oligo- nucleotides: 5¢-ACTACCGAACGGGCC CCCGGGGTC AGACTGGACACATGG-3¢ and 5¢-TCGGGCCATGGC ATG CCCGGGGGTCAGAGCTGGG-3¢ for amplifica- tion of D4 of GCSFR and 5¢-TACTCTCAAGAAATG CCCGGGTCCCATGCCCCAGAG-3¢...
  • 11
  • 583
  • 0