... 052. ApproachtothePatient with a Skin Disorder (Part 1) Harrison's Internal Medicine > Chapter 52. ApproachtothePatientwith a Skin Disorder APPROACH TOTHEPATIENTWITH ... assume that the erosion is the primary lesion andthe redness and scale are secondary, while the correct interpretation would be that thepatient has a pruritic eczematous dermatitis with erosions ... Fig. 52-3) andto formulate a differential diagnosis (Table 52-4). For instance, the finding of scaling papules (present in patients with psoriasis or atopic dermatitis) places thepatient in...
... elicits the desire to scratch. Pruritus is often the predominant symptom of inflammatory skin diseases (e.g., atopic dermatitis, allergic contact dermatitis); it is also commonly associated with ... Table 52-3 Common Dermatologic Terms A schematic representation of several common primary skin lesions (see Table 52-1). Chapter 052. ApproachtothePatient with a Skin Disorder (Part ... epidermal atrophy). Scar: A change in the skin secondary to trauma or inflammation. Sites may be erythematous, hypopigmented, or hyperpigmented depending on their age or character. Sites on hair-bearing...
... MD; with permission.)[newpage] APPROACH TOTHE PATIENT: SKIN DISORDER In examining the skin it is usually advisable to assess thepatient before taking an extensive history. This way, the ... important individual skin lesions and make it possible to assess the distribution of the eruption accurately. The Chapter 052. ApproachtothePatient with a Skin Disorder (Part 4) Figure ... correlates highly with diagnosis (Fig. 52-6). For example, a hospitalized patientwith a generalized erythematous exanthem is more likely to have a drug eruption than is a patientwith a similar...
... is characterized by small and large erythematous papules and plaques with overlying adherent silvery scale. Figure 52-8 Chapter 052. ApproachtothePatient with a Skin Disorder (Part...
... lesions with a generalized arrangement are common and suggest a systemic etiology. Figure 52-9 Erythema multiforme. This eruption is characterized by multiple erythematous plaques with ... represents a hypersensitivity reaction to drugs (e.g., sulfonylamides) or infections (e.g., HSV). (Courtesy of the Yale Resident's Slide Collection; with permission.) Figure 52-10 ...
... against the surface of the skin and rotated with downward pressure until it penetrates tothe subcutaneous tissue. The circular biopsy is then lifted with forceps, andthe bottom is cut with iris ... of systems 9. Family history (particularly relevant for patients with melanoma, atopy, psoriasis, or acne) 10. Social, sexual, or travel history as relevant tothepatient DIAGNOSTIC TECHNIQUES ... gently with a no. 15 scalpel blade, andthe removed scale is collected on a glass microscope slide then treated with 1 to 2 drops of a solution of 10–20% KOH. KOH dissolves keratin and allows...
... of these cytochromes have been proposed to be ter-minal Fe(III) and Mn(IV) reductases, although their role in the reductionof other metals is less well understood. To obtain more insight into ... anaerobicgrowth on either of the electron acceptors U(VI) and Se(VI) is due tothe decaheme cytochromes c notrecognizing either of these electron acceptors, weprobed the relative affinities via ... involved in the reduction of either Fe(III) or Mn(IV) in MR-1 isthought to be composed of cytochromes and a qui-none, located in both the cytoplasmic membrane(CymA and menaquinone) andthe outer...
... joints. The fingers are named in order: the thumb, the index, the middle, the ring, andthe little finger. Their different lengths cause them to fit the hollow of the hand when it is closed, and ... as they contract and expand alternately, the bone to which they are attached is moved toand fro. (See p. 275.) If you grasp the arm tightly with your hand just above the elbow joint, and ... forward, but the muscles of the calf neutralize this action. The ankle, the knee, andthe hip lie in nearly the same line, and thus the weight of the body rests directly on the keystone of the arch...
... important to take a detailed history to decipher the source of the symptoms and to target treatments. A functional history is important to determine how the disease process as well as the aging ... relaxation and self-hypnosis training.24 Generally, these approaches teach patients to monitor their bodies for signs of stress, to engage in deep breathing and other stress management approaches, ... intolerance, fatigue, pain, and bowel and genitourinary dysfunction.As thepatientwith MS ages, morbidities and physiological changes associated withthe normal aging process interact with...
... male and female, synthetic and real with different regional accents, these cues discriminate between the simplest speech segments containing an element in a minimal combination with others. ... terms of total amplitude or energy distribution ED across low, middle and high frequency parts of the vocal range and the angular frequencies to( F) and amplitudes a(F) of formants. The first ... steady- state formant values at the centre of a segment with values at entrance and exit boundary. They describe the context of a segment without going tothe computational complexity of...