application of sbdd to the discovery of new antibacterial drugs
Báo cáo khoa học: A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin pot
... matching of protein spots first to reference gels of the same condition and thereafter to reference gels common to both conditions The stepwise annotation of protein spots to two independent levels of ... (Fig 1) The four level match-sets are the reference gels of the respective quadrants from the 2D gel sections of each condition and the four higher-level match-sets are the reference gels of the ... the major role of the MMP family is the control of cellular responses critical to homeostatic regulation of the extracellular environment and the immune response [19,20] We decided to apply protease...
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ỨNG DỤNG CÔNG NGHỆ MỚI TRONG NUÔI TRỒNG THỦY SẢN APPLICATION OF NEW TECHNOLOGY ON AQUACULTURE
... thnh v trỡ biofloc ao nuụi tụm i T l N/P T lờ N/P quyt nh thnh phn to (t dng) hay vi khun d dng chim u th ao N/P < 10, dinoflagellata (to giỏp) chim u th N/P = 10-20, to lc, to silic, to giỏp v ... 10 o Nuụi tụm ng dng cụng ngh biofloc (hon ton khụng cú vi to) : Lng carbohydrat b sung bng khong 50% lng thc n o Nuụi tụm vi cụng ngh semi-biofloc (cú kốm theo vi to) : Lng carbohydrat b sung bng ... Thnh phn biofloc bao gm: Hn hp cỏc vi sinh vt d dng (vi khun to floc v vi khun si), mnh vn, keo, polymer sinh hc, cation, t bo cht, mui tinh th, Bỏm vo biofloc cũn cú vi to (to si, to silic),...
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DEVELOPMENT AND APPLICATION OF NEW APPROACHES FOR STUDIES OF INFLUENZA INDUCED INFLAMMATION AND DNA DAMAGE
... measures of inflammatory cell infiltration, RONS-induced damage to macromolecules, and molecular responses to DNA damage together call attention to the importance of the immune response in the induction ... during the S and G2 phases of the cell cycle [51], possibly to facilitate HR activity that repairs DSBs predominantly in the presence of newly synthesized sister chromatids [20, 52] Nevertheless, the ... apoptotic markers peaked at dpi which coincides with the kinetics of induction of cH2AX foci These results raise the possibility that DNA damage, especially from to dpi, contributes to apoptosis...
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DEVELOPMENT AND APPLICATION OF NEW APPROACHES FOR STUDIES OF INFLUENZA INDUCED INFLAMMATION AND DNA DAMAGE
... HA first binds to sialylated host receptors that facilitate the entry of the virus into host cells via receptor – mediated endocytosis Endosomal acidity then triggers the fusion of viral and endosomal ... passage for vRNP complexes to enter the cytosol M2, a proton ion channel, further pumps H+ into the viral core, decreasing the pH of the viral core and disrupting the interactions between vRNP ... lung injury The onset of severe illnesses due to influenza infection is often due to infection spreading from the upper respiratory tract to the lower respiratory tract A proportion of patients...
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báo cáo hóa học: " Knowledge discovery in databases of biomechanical variables: application to the sit to stand motor task" docx
... in the movement are needed as model inputs The outputs of the TIPs are the kinematic and kinetic variables associated with the actuators During BSO the TIP is applied to the upper part of the ... kinetic variables of the main actuator are strongly related to each other and their timing Given a value of one of them, a limited range of values is to be expected for the others Moreover, 'average' ... characteristics, that most often a low power before seat-off is related to a regular occurrence of time instants and to low -to- medium sagittal speed from seat-off to the end of the task The patterns found...
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The application of games in teaching grammar with reference to tieng anh 10 textbook at ha trung high school, thanh hoa province
... 2 Given the rationale and the aims of the study, it is necessary to limit the study to the areas which are manageable Benefits of the application of games in teaching grammar create the effectiveness ... them all The picture draws a man and a woman in the clothes store 17 The teacher asks the students to work in groups They have to show the differences between sentences, about the form and the ... right the questions their teacher prepared Therefore, the time for the students to speak is much (70 - 79%) Most of the students often raise their hand and answer right, so the classmates clap their...
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Customer satisfaction: review of literature and application to the product-service systems
... collected data, due to the general nature of these tools and availability of sources, which can provide help in these respects 2.4 Outline of the report An overview of the sections of the report is ... organisation of repair and maintenance of tools and their final disposal at the end of their life For the example of the tool library, the following attributes could be suggested in the above context ... attempt to develop new PSS is vital Development of new offers is a time consuming matter that requires involvement of a number of actors, often of those who are usually considered to be outside of the...
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Tài liệu Mapping TOEFL® iBT Scores to the CEFR: An Application of Standard ... pdf
... Purpose • Identify scores on TOEFL® iBT corresponding to the six proficiency levels of the CEFR – A1 and A2 (Basic) – B1 and B2 (Independent) – C1 and C2 (Proficient) • Focus on candidates ... range of topics in field of interest Sustains conversation with degree of fluency and spontaneity Takes listener and cultural context into account Speaks without causing undue stress to the listener ... Angoff Approach • What is the probability that a “just qualified” A2, B2, C2 candidate would know the correct answer? Or • How many of 100 JQCs would know the correct answer? • Three rounds of...
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AN ACTION RESEARCH ON THE APPLICATION OF COOPERATIVE LEARNING TO TEACHING SPEAKING TO THE SECOND YEAR SUDENTS AT THE DEPARTMENT OF ENGLISH, GIA LAI TEACHERS' TRAINING COLLEGE
... experts with the same topic meet in a corner of the classroom to learn about their topic Then they prepare a brief presentation on the material and return to their base teams They teach their base ... by the tendency of some learners to dominate the group, while others speak very little or not at all • Mother-tongue use: When all, or a number of the learners share the same mother tongue, they ... the collaboration of many individuals (the actors, the director, the editor, the scriptwriter, the cinematographer…ect.) who not only try to fulfill their duties, but also share the responsibilities,...
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Slide an investigation into some approaches to vocabulary teaching and learning and the application of games in teaching and learning vocabulary at pre – intermediate level at foreign language center – haiphong university
... (Wilkins, 1972, p.111) Rationale Aims of the study Scope of the study Methods of the study Design of the study Research questions: What is the present situation of teaching and learning vocabulary ... encourage learners to interact and communicate with one another When taking part in the games learners have to talk to express or exchange their ideas with their partners It can lead to better word ... Through interaction with others, learners can get help from each other on the meaning of unfamiliar words, including vocabulary items they not know (Nation and Newton, 1977, p.244) Part two:...
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difficulties in teaching reading comprehension with the new english textbook “tieng anh 10” (the set of standard textbooks) to the 10th form students at ke sat high school
... stage of the lessons They ask their students to make prediction on the basis of the title of the unit, the pictures enclosed the passages, the students' background knowledge about the topic they ... students to skim to decide which of the options below is the best title for the passage: A The story of a film maker B A brief history of cinema C The history of the film industry The teacher instructs ... is the design of the reading period of Unit "The story of my village" (Time: 45') (see Appendix 7) * The aim of the lesson: Reading about the changes in the country life * The objectives of the...
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Tài liệu Bringing Social Impact Bonds to New York City: The City of New York pdf
... oversees the day -to- day implementation of the project and manages the Osborne Association and Friends of Island Academy, the two non-profit service providers that deliver the intervention; • The Vera ... is relatively new and New York City will be the first in the nation to implement this innovative financing model What are the Benefits? • Investing in outcomes to improve the lives of those in ... loan to MDRC, a leading non-profit • The Goldman Sachs loan to MDRC will ensure successful implementation of the ABLE program at Rikers • Bloomberg Philanthropies will make a grant to MDRC in the...
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Tài liệu Which Bank Is the “Central” Bank? An Application of Markov Theory to the Canadian Large Value Transfer System doc
... transactions in the LVTS from October 1st 2005 to October 31st 2006 This data set consists of 272 days in which the LVTS was running The participants in the sample consist of members of the LVTS and the ... vector is our prediction for the distribution of daily liquidity The bank with the highest value in the stationary vector is predicted to hold the most liquidity throughout the day and is thus the ... order of magnitude) The BCLs are fairly symmetric since the minimum through the 50th percentile of absolute differences of the BCLs between pairs of banks are zero and even the 75 percentile of the...
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Tài liệu A Matter of Security The Application of Attachment Theory to Forensic Psychiatry and Psychotherapy pptx
... feeling of anger (the idea of anger rather than the experience of anger) may be used to simulate and so to infer the THE DEVELOPMENTAL ROOTS OF VIOLENCE IN THE FAILURE OF MENTALIZATION 25 other’s ... Thomas 2000) The explosives they brought with them, had they detonated, would have put the death toll into the hundreds During the attack, the boys excitedly discussed which of their classmates ... because they are able to attribute a false belief to her The acquisition of this capacity has come to be known as the development of a theory of mind ‘Theory of mind’ is an interconnected set of beliefs...
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Tài liệu Effect modification of air pollution on Urinary 8-Hydroxy-2’-Deoxyguanosine by genotypes: an application of the multiple testing procedure to identify significant SNP interactions ppt
... of interaction terms of individual SNP and pollutant The current version of MTP allows one to identify the significance of a group of candidate variables to reduce the false discovery rate meanwhile ... 145 (48.82) *The sum of the subjects in each genotype may not add up to the total number of subjects due to missing genotyping data Missing genotyping is due to a variable number of samples for ... advantage of this method as opposed to only rejection or not of hypotheses, is that it is not needed to determine the level of the test in advance This study reported adjusted p-values Then, we...
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Tài liệu THE VALUE OF IMPROVED PUBLIC SERVICES: AN APPLICATION OF THE CHOICE EXPERIMENT METHOD TO ESTIMATE THE VALUE OF IMPROVED WASTEWATER TREATMENT INFRASTRUCTURE IN INDIA docx
... attributes considered, and the vectors of coefficients to n are attached to the vector of attributes (Z) The assumptions about the distribution of error terms implicit in the use of the CLM impose a particular ... the number of household specific characteristics employed to explain the choice of the wastewater treatment programme alternative, and the vector of coefficients to l are attached to the vector ... of the public‟s preferences with respect to improvements to the STPs and hence to the quality of the water in the Ganga 11 The choice experiment survey was administered to be representative of...
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