... developing brain In order to determine whether active inflammation, including HMGB1 and pro-inflammatory cytokines, occurs inchildrenwith febrile seizures and pediatric epilepsy, we analyzed cytokine ... role of cytokines in epileptogenesis remains to be elucidated Cytokines may contribute initially to incite seizures in the developing brain after being induced by seizure or tissue injury, and they ... patients In addition, IL-1b levels were significantly and positively correlated with HMGB1 levels andwith other pro-inflammatory cytokines (IL-6 and TNF-a), supporting the association of the cytokine...
... Meanwhile, we found that childrenwith PE did not have more behavioural problems than control group This finding is also in line with studies of psychosocial functioning inchildrenwith PE [8,19], but ... information could be included All of the interviews were conducted by authors They had been trained in interviewing and administering questionnaires Answers were recorded and collected after a ... of 24013 Chinese childrenand adolescents between the age of and 16 years The cutting points for clinical designation are based on raw scores 12.9% of the children had scores in the clinical range...
... following acoustic cues There is a particular interest in analysing inhibition deficits following auditory cues inchildrenwith ADHD as a high number of childrenwith ADHD have difficulties with ... was to investigate how childrenwithand without ADHD differ in brain activation during an antisaccade task The second aim was to investigate, whether childrenwith ADHD have comparable inhibition ... checklist [39] and a routine questionnaire while children completed the Edinburgh-Handedness-Inventory [40] To ensure within-normal hearing levels, children s hearing thresholds were determined for...
... detected in individual patients The incidence of coinfection decreased with the number of pathogens in past-infected and uninfected childrenIn the primary -infection group, the most frequent combination ... children than in the other groups In the primary -infection and uninfected groups, the proportion infected with PIV was the same and was significantly higher than inchildrenwith past EBV/CMV infection ... primary infectionwith multiple pathogens B EBV/CMV primary infectionwith a single or no other pathogen C EBV/CMV past infectionwith multiple pathogens D EBV/CMV past infectionwith a single...
... CXC and CC chemokines during the initial phase of meningococcal sepsis inchildrenand to determine their relationship with disease severity and outcome Materials and methods Patients Childrenwith ... Bartelink AK, van Dalen R, Sauerwein RW, van der Meer JW: Correlation between proinflammatory cytokines and antiinflammatory mediators and the severity of disease in meningococcal infections J Infect ... Brandtzaeg P, Halstensen A, Kierulf P, Espevik T: The complex pattern of cytokines in serum from patients with meningococcal septic shock Association between interleukin 6, interleukin 1, and...
... (21 males and 27 females) consisted of 42 childrenwith HgbSS andwith HgbSC The control group (17 males and 31 females) included 41 childrenwith HgbSS andwith HgbSC The age of the children ... paucity of research investigating patients with concomitant asthma and sickle cell disease Table 2: Results inchildrenwith sickle cell disease withand without asthma Patients with Sickle Cell ... patients with sickle cell disease without asthma in those presenting with vaso-occlusive pain crises Methods We performed a 5-year retrospective chart review of 48 childrenwith asthma and sickle...
... surgery/interventions (including ablations) 1.1 Without remaining findings (complete correction) 1.2 With minimal findings 1.3 With clinically significant findings 1.4 After palliative interventions: ... Cardiac function and hemodynamic findings under exertion BOX Findings after cardiac surgery and/ or interventions Minor remaining findings (1.2) – Scar after ventriculotomy – Incomplete right ... forms of exercise and games in childhood Types of exercise with a high dynamic/low static component Running, skipping, jumping, cycling, swimming, inline skating, skateboarding, running games, ball...
... endothelin, surviving, etc We have obtained data indicating that a-defensin-1 and a-defensins-2 induce an increase in the protein content of cyclin D and that quercetin inhibits the a-defensininduced ... by a-defensin-1 and a-defensin-2 (Fig 3A–C) These results indicate that a-defensin-induced increases in lung fibroblast proliferationand collagen synthesis involve the b-catenin signaling pathway ... treated without or with a-defensin-1 and a-defensin-2 (2.5 lm) in the presence and absence of quercetin (10 lm) was determined As shown in Fig 4, incubation of lung fibroblasts with a-defensin-1 and...
... tachykinins and neurokinins Trends Pharmacol Sci 2000;21: 173–175 6- Almeida TA, Rojo J, Nieto PM, Pinto FM, Hernandez M, Martin JD, et al Tachykinins and tachykinin receptors: structure and activity ... autoimmune diseases and neural dysfunction points to an involvement linking the nervous and the immune system In this context, neuropeptides, including tackykinins and neurotrophins have been recognized ... allergens, infectious agents and heavy metals), with a subequent increase in the release of this tachykinin from these cells Neuroendocrine hormones, including tackykinins, triggered during stress...
... non-ASD/SPAD children Case description ASD/SPAD children: Eight ASD/SPAD children characterized by fluctuating (worsening) behavioral/cognitive skills following immune insults including viral infectionand ... the Institute of Genomic Medicine, UMDNJ-NJMS He has been involved in clinical studies of CGH, transcription profiling, and microRNA profiling in patients with various medical conditions including ... These children were not included in the current study We refer ASD/SPAD children as these ASD/SPAD childrenwith worsening behavioral symptoms and cognitive skills with immune insults in this...
... cells in tissue culture provides a potential mechanism for increasing invasive mammary carcinoma [5] and induced colonic neoplasia in animal models [6] Borax is used as a food additive in some ... immune cell still need to be investigated for food additive carcinogenesis The defect in genetic material and immune cell development involves in human carcinogenesis In this study, we studied about ... chromosome-banding patterns In human chromosomes, SCEs occur preferentially in Q-negative bands or at the junction of Q-positive and Q-negative regions [10] The toxic effects of borax to immune cell proliferation...
... Measuring health-related quality of life inchildrenwith cancer living in mainland China: feasibility, reliability and validity of the Chinese mandarin version of PedsQL 4.0 Generic Core Scales and ... The findings support the feasibility, reliability and validity of the Chinese Mandarin version of PedsQL 4.0 Generic Core Scales and 3.0 Cancer Module inchildrenwith cancer living in mainland ... testing responsiveness of the Chinese mandarin version scales in longitudinal studies andin other areas, particularly in rural areas Studies measuring HRQOL inchildren who have refused or abandoned...
... concepts in the management of H pyloriinfection recommend that H pyloriinfection should be sought for and treated in patients with unexplained IDA andin those with IPP [152] H pyloriinfection ... personnel and H pyloriinfection within the family have been suggested for high recurrence rate of H pyloriin developing countries [230] Recurrence of H pyloriinfection is defined as the situation in ... an indication for a test and treat strategy for H pyloriinfectioninchildren [152] It is important to determine the cause of presenting gastrointestinal symptoms and not the presence of H pylori...
... often occur in infants and young children [7] As such, in the clinical setting active range of movement of the child's affected limb is infrequently measured with a goniometer or inclinometer Rather ... with age [13,18] and the symptoms of OBPP are exacerbated with age and produce increasing disability [20], our results provide a justification to monitor and maintain upper limb movement in children, ... joint movements, such as shoulder flexion and elbow extension, in positions where gravity is eliminated and against gravity Movement is quantified on an eight-point ordinal scale, with equating...
... distally, crossing above the humerus From the other incision, in line with the respected conjoined tendon, the tunnel is completed moving over the humerus, to join the dissecting finger(s) from ... 60A:691-695 In a continous series from July 2005 to March 2009, we performed the tmm transfer in 17 children aged to 17 years, and obtained improvements both in shoulder abduction (between 15 and 70°) and ... Journal of Brachial Plexus and Peripheral Nerve Injury 2009, 4:20 Figure explaining the harvest and transposition of the teres major muscle Scheme Scheme explaining the harvest and transposition of...
... taking anti-hypertensive treatment The following classes of drugs were employed: a-adrenoceptor antagonists in one MHD and two CT, ß-blockers in nine MHD, ACE inhibitors in seventeen MHD and ... CT, and Ca channel blockers in twenty-nine MHD and ten CT Subjects were taking their medication when ACE activity was measured and no influence of medication on the measurement In 1967, Ng and ... linked, however, to an unidentified functional mutation in the AT1R gene Page of 10 or in another closely linked gene possibly located in regulatory regions and involved in the development and...
... taking anti-hypertensive treatment The following classes of drugs were employed: a-adrenoceptor antagonists in one MHD and two CT, ß-blockers in nine MHD, ACE inhibitors in seventeen MHD and ... CT, and Ca channel blockers in twenty-nine MHD and ten CT Subjects were taking their medication when ACE activity was measured and no influence of medication on the measurement In 1967, Ng and ... linked, however, to an unidentified functional mutation in the AT1R gene Page of 10 or in another closely linked gene possibly located in regulatory regions and involved in the development and...
... type, and combined type, according to the predominant clinical manifestations of inattention, hyperactivity, and impulsivity The validity of DSM-IV ADHD predominantly inattentive and combined ... cutoff point of 60, instead of 70, was effective in discriminating between ADHD patients withand without comorbid diagnoses [45] Racial and ethnic differences in psychopathology and symptom severity ... sustainable improvements in ADHD clinical symptoms and neurocognitive function in realistic clinical settings Second, whether the differences in ADHD clinical symptoms and neurocognitive functions...
... classic Nitrogen-containing biophosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras Originally published in Volume 7, number ... Rogers MJ: Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras J Bone Miner Res 1998, 13:581-589 ... by extinction at 260nm; the contamination with proteins was determinated with the 260/280 ratio To detect the mRNA of cyclin D1 and collagen type I in osteoblasts, primers were designed using NCBI-nucleotide...