and possibly its function
Báo cáo y học: "Primary lower limb lymphedema: a focus on its functional, social and emotional impac"
Ngày tải lên :
25/10/2012, 11:40
... bodily pain, vitality, mental health, social functioning, and general health SF-36 metric patterns of the two patients were registered and are shown in Table and a description of these two cases follows ... psychological distress and sexual dysfunction in patients with lymphedema were low levels of social support [10] It was surmised that social support may help combat fears of abandonment and feelings of ... their conditions and using generic metric tools for the assessment of physical and mental deficits represent both approaches that in conjunction can effectively follow-up rare, and commonly related...
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Báo cáo khoa học: Mycobacterium tuberculosis ClpC1 Characterization and role of the N-terminal domain in its function ppt
Ngày tải lên :
23/03/2014, 06:20
... ClpC1 and its deletion mutants (A) SDS ⁄ PAGE of purified full-length ClpC1 and deletion mutants, ClpC1D1 and ClpC1D2 (B) Full-length ClpC1 and deletion mutants, ClpC1D1 and ClpC1D2; the first and ... repeat I and the intervening sequence between repeats I and II deleted, and the N-terminal repeat II forms its N-terminus (Fig 2B) The deletion mutants were also expressed in E coli and purified ... recombinant M tuberculosis ClpC1 functioned like an ATPase, we investigated the contribution made by its N-terminus to its functional activity Two deletion variants, ClpC1D1 and ClpC1D2 were generated...
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Báo cáo hóa học: " Graphene on ferromagnetic surfaces and its functionalization with water and ammonia" doc
Ngày tải lên :
21/06/2014, 05:20
... (Eint) and the equilibrium distances (d0) between H2O and the surface of the freestanding graphene layer as obtained for the six selected geometries at DFT level with standard PBE functional and ... contributions SB, MW and YSD carried out the experiment and perform treatment of experimental data SB and ENV performed the calculations YSD conceived of the study, and participated in its design and coordination ... Graphene on ferromagnetic surfaces and its functionalization with water and ammonia Nanoscale Research Letters 2011 6:214 Submit your manuscript to a journal and benefit from: Convenient online...
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Báo cáo y học: "The telosome/shelterin complex and its functions" doc
Ngày tải lên :
14/08/2014, 20:22
... avenue of research for probing the function of TRF1 and TRF2, and deciphering how players from diverse pathways are recruited to the telomeres POT1 and TPP1 and their functions While the telosome forms ... complex itself [11] TIN2 and TPP1 are critical to its assembly [65], and the ssDNAbinding protein POT1 serves as the effector of the complex in its role of maintaining telomere integrity Both POT1 and ... of the telosome and with a diverse array of proteins and protein complexes that are involved in the cell cycle and in DNA repair and recombination, to maintain telomere structure and length [2,21-28]...
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THE MECHANISMS REGULATING THE TRANSCRIPTION FACTOR ATF5 AND ITS FUNCTION IN THE INTEGRATED STRESS RESPONSE
Ngày tải lên :
24/08/2014, 11:17
... five subunits α, β, γ, δ and ε (18-20) eIF2B γ and ε share sequence homology and form a binary catalytic subcomplex that catalyzes the regeneration of eIF2-GTP The α, β and δ subunits form the ... Yang, and my motherand father-in-law, Xihong Mo and Bin Zhong, for making the life of my wife and kids at home infinitely easier Finally, this thesis is dedicated to my daughters, Jiaming and Jiayi, ... myself and reach beyond what I first thought impossible These include my brother and sister: Dongjie and Wenzhao, Jingliang Yan, Lin Lin and Sixin Jiang I would like to thank my parents, Xin Zhou and...
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Identification and characterization of protein kinase CK2 as a novel interacting protein of neuronal CDK5 kinase and its functional role in microtubule dynamics
Ngày tải lên :
16/09/2015, 17:10
... α’ subunits and two regulatory β subunits We showed that the α subunit of CK2 binds directly to both microtubules and tubulin heterodimers The CK2 holoenzyme (but not its individual subunits) exhibited ... values for the α and α’ subunits ranges from 35 to 44 kDa (Hathaway and Traugh, 1982; Litchfield et al., 1990) The α, α’ and β subunits are the products of three distinct genes (Allende and Allende, ... and its immunoreactivity as predominantly cytoplasmic (Singh and Huang, 1985; Girault et al., 1990) Using immunofluorescence and immunoelectron microscopy, Yu and coworkers showed that CK2α and...
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Tài liệu FINANCE AND THE ENGINEERING FUNCTION pdf
Ngày tải lên :
26/12/2013, 01:18
... middle management and staff groups such as engineers and marketers The purposes and uses of accounting systems, data, and reports are quite different for different people and functions in the ... engineer needs to understand accounting principles and processes as they apply to his or her function and also to understand the way in which others of the enterprise view business and what their information ... expense that may be charged against profits in future years The understanding of this principle of depreciation is critical to the later understanding of profits and cash flow 69.3.8 Total Capital...
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08 TAYLOR MODELS AND OTHER VALIDATED FUNCTIONAL INCLUDING METHOD MAKINO & m BERZ
Ngày tải lên :
12/01/2014, 21:47
... occurring trigonometric functions can be bounded exactly and there is no dependency On the other hand, CF, MF, and TM not have the ability to treat the trigonometric functions exactly, and will in these ... models (Pf +g , If +g,h ) and (Pf ãg , If ãg,h ) for the sum and products of f and g obtained via addition and multiplication of Taylor models satisfy If +g,h = O(hn+1 ), and If ãg,h = O(hn+1 ) ... y, z) = (5.2) and the function is dened for < x < 8, y > 0, and z 6= We study the behavior on the domain interval boxes (2, 1, 1)+ [2j , 2j ]3 and show the results in Figure As a function of j,...
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Tài liệu Central Bank Policy Rate Guidance and Financial Market Functioning∗ doc
Ngày tải lên :
17/02/2014, 03:20
... forecast is determined endogenously along with inflation and output using their Forecasting and Policy System model (see McCaw and Ranchhod 2002, and Ranchhod 2003) Vol No Central Bank Policy Rate ... these arguments, and based on our experience with conducting event studies for the United States and Canada (see Gravelle and Moessner 2002), we use daily data in this study Drew and Karagedikli ... always preceded (and was taken by market participants to imply) a tightening at the next meeting, and “close monitoring” preceded unchanged policy In contrast to the RBNZ, the FOMC and the ECB have...
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Tài liệu Báo cáo khoa học: Protein kinase CK2 activates the atypical Rio1p kinase and promotes its cell-cycle phase-dependent degradation in yeast pdf
Ngày tải lên :
18/02/2014, 16:20
... (wild-type, Dcka1, Dcka2) Cka1p and Cka2p less efficiently by a heterotetramer composed of two Cka2p subunits, and only poorly by the two Cka1p catalytic subunits-comprising holoenzyme The observed ... between Rio1p and Cka1p or Rio1p and Cka2p, respectively, in yeast strains disrupted for either CKA1 or CKA2 Genotypes are indicated below (C), and alleles in brackets denote the tagged (and immunoprecipitated) ... to yeast Rio1p and have both a CK2- and a K-domain, although the direct sequence similarity is low We have cloned both types of human cDNAs, ad 034 and SUDD, as myc3tagged version and expressed...
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HOW TO VALUE YOUR BUSINESS AND INCREASE ITS POTENTIAL doc
Ngày tải lên :
06/03/2014, 09:22
... understand how to a “quick -and- dirty” valuation, in order to manage your business over time to maximize its value and to plan your retirement and exit strategies However, there are other business and ... READER H ow to Value Your Business and Increase Its Potential will teach you just that: How to value your business “quick and dirty,” and how to manage it to increase its worth I have written it primarily ... Value? There are many different concepts and definitions of value, and it is important to understand how to sort through and make sense of them While the theory and mechanics of measuring value will...
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Báo cáo khoa học: Interactions between metals and a-synuclein ) function or artefact? pptx
Ngày tải lên :
07/03/2014, 10:20
... metals and a-synuclein as it is known that mixing human and mouse a-synuclein inhibits the ability of the protein to aggregate [53] Therefore, the animal models based on neurotoxins such as MPTP and ... than beta- and gamma-synuclein and cannot cross-seed its homologs J Biol Chem 275, 34574–34579 27 Hashimoto M, Rockenstein E, Mante M, Mallory M & Masliah E (2001) Beta-synuclein inhibits alpha-synuclein ... nitrative stress and pathological inclusions in Alzheimer’s and Parkinson’s diseases Free Radic Biol Med 32, 1264–1275 48 Lee MK, Stirling W, Xu Y, Xu X, Qui D, Mandir AS, Dawson TM, Copeland NG, Jenkins...
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Báo cáo khoa học: Identification of yeast aspartyl aminopeptidase gene by purifying and characterizing its product from yeast cells potx
Ngày tải lên :
07/03/2014, 12:20
... coordination, function, and structure of zinc enzymes and other proteins Biochemistry 29, 5647–5659 Wilk S, Wilk E & Magnusson RP (2002) Identification of histidine residues important in the catalysis and ... activity in Mono Q fractions I and II using a Superose column (s, d) Activity of fractions I and II, respectively (B, C) Results of SDS ⁄ PAGE analysis of fractions I and II Lane numbers correspond ... mammalian and yeast enzymes First, the subunit composition differs Mammalian aspartyl aminopeptidases comprise eight identical subunits, whereas the yeast enzyme contains 12 identical subunits Second,...
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Stored Procedures, Triggers, and User-Defined Functions on DB2 Universal Database for iSeries doc
Ngày tải lên :
17/03/2014, 00:20
... User-defined functions and user-defined table functions UDFs and user-defined table functions (UDTFs) are user-written programs that enrich the functionality of the database manager by adding new functions ... 13.5.1 UDF overloading and function signature 13.5.2 Parameter matching and promotion 13.5.3 Function path and the function selection ... include working with the Linux and Microsoft® Windows® environment on the System i platform, DB2 and WebSphere in OS/400, i5/OS, and Linux, and Lotus® over OS/400 and i5/OS environment Daniel Lema...
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Báo cáo Y học: The phosphotransferase system of Streptomyces coelicolor IIACrr exhibits properties that resemble transport and inducer exclusion function of enzyme IIAGlucose of Escherichia coli pptx
Ngày tải lên :
17/03/2014, 23:20
... NdeI and BamHI and cloned into plasmids pET15b and pET3c (Novagen) resulting in crr expression plasmids pFT41 and pFT42, respectively [22] A two-step PCR mutagenesis procedure as described by Landt ... His-tagged HPr (67 pmol), and of S coelicolor IIACrr and IIACrr(H72A) (235 pmol) The following combinations were examined: lane 1: EI, HPr, and IIACrr; lane 2: EI and HPr; lane 3: EI and IIACrr; lane ... coupling reaction was 1200 resonance units (71 fmoles) for His-tagged IIACrr, 450 resonance units (24 fmoles) for his-tagged IIAGlc, and 1500 resonance units (60 fmoles) for His-tagged TetR For...
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Báo cáo khoa học: Peptides that bind the HIV-1 integrase and modulate its enzymatic activity – kinetic studies and mode of action pptx
Ngày tải lên :
22/03/2014, 16:21
... proteolysis and thus are metabolically stable [2233] For example, a peptide that bears the functional domain of the HIV envelope protein gp41, and competitively inhibits viral cell fusion and thus ... ) and no peptide (*)] IN strand-transfer activity was measured as described previously [58] and in Experimental procedures The Km and Vmax values for each IN peptide ratio were calculated and ... to IN decreases its afnity for DNA; peptides that slightly increase the Km but, in addition, modify the Vmax and Kcat values; and peptides that bind IN, but have no effect on its activity Structural...
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Counseling Psychology and Optimal Human Functioning pptx
Ngày tải lên :
22/03/2014, 18:20
... A.Achter and David Lubinski 25 Individuality and Optimal Human Functioning: Interests, Self-Efficacy, and Personality Fred H.Borgen and Lori D.Lindley 55 Person-Environment Psychology and Well-Being ... Strategies and goals involving the conduct and meaning of life; limits of knowledge and uncertainties of the world; excellence of judgment and advice; knowledge with extraordinary scope, depth, and ... belongingness and rootedness, they are satisfied in their love needs, have friends and feel loved and loveworthy, they have status and place in life and respect from other people, and they have...
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Báo cáo khoa học: Making sense of G-quadruplex and i-motif functions in oncogene promoters pot
Ngày tải lên :
23/03/2014, 03:20
... single-stranded purine or pyrimidine strands) and whether enzymatic-induced cleavage of the NHE III1 occurred It now appears that NM23H2 binds to both the purine and pyrimidine strands of NHE ... single-stranded purine-rich strand and then stabilized the resulting structure [25] Furthermore, nucleolin bound more avidly to the c-Myc G-quadruplex than its previously suggested RNA substrate and ... loop sizes and base composition (e.g one to seven and bases that have specific interactions), number of tetrads (i.e two, three or four) and inter-quadruplex binding sites in c-Myb and hTERT represents...
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