and iga enriched immunoglobu lins in the treatment of sepsis and septic shock
Báo cáo khoa học: "Intravenous colistin in the treatment of sepsis from multiresistant Gram-negative bacilli in critically ill patient" ppsx
... creatinine at initiation of colistin; Cr2, highest value of creatinine during treatment with colistin; Cr3, serum creatinine days after completion of treatment with colistin; CVVHD, continuous ... number of patients, the concomitant use of β-lactams, and the absence of a control group in the study not allow for a clear verdict on the clinical effectiveness of colistin On the other hand, the ... patients died within 48 hours of the initiation of colistin; these patients were not included in the analysis because they were not considered true therapeutic failures Data on the remaining 24 patients...
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Báo cáo khoa học: "The place of early haemoperfusion with polymyxin B fibre column in the treatment of sepsis" pdf
... understanding of the real efficacy of this therapy Competing interests The author(s) declare that they have no competing interests References The biological versus the clinical clock 632 Despite the ... infection The latter approach has been undertaken by a group of investigators coordinated by two centers, including ours, in the EUPHAS (Early Use of Polymixin-B Hemoperfusion in Abdominal Sepsis) ... important, especially at the beginning of the syndrome, but they not have a causative approach or remove the origin of sepsis In this setting, physiological end-points such as reduction in vasopressor...
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Báo cáo khoa học: "The key advance in the treatment of sepsis in the last 10 years … doing less" pot
... AR, Young D, Black N, Rowan K: Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland Crit Care Med 2003, 31:2332-2338 Annane ... treatment of severe sepsis and septic shock N Engl J Med 2001, 345:1368-1377 Hayes MA, Timmins AC, Yau EH, Palazzo M, Hinds CJ, Watson D: Elevation of systemic oxygen delivery in the treatment of critically ... R: Intensive insulin therapy in the medical ICU N Engl J Med 2006, 354:449-461 Singer M, Glynne P: Treating critical illness: the importance of first doing no harm PLoS Med 2005, 2:e167 Page of...
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Báo cáo y học: "Pro/con clinical debate: Are steroids useful in the management of patients with septic shock" ppt
... reasonable and appropriate Con: steroids are not useful in the management of septic shock Katherine G Craig and Keith R Walley The debate surrounding the use of corticosteroids in septic patients ... mortality in septic shock [3] Corticosteroids can regulate the synthesis and function of catecholamines and their receptors, which in turn control vascular tone and organ perfusion [4] Proinflammatory ... and newer, yet preliminary, The patient described in the present scenario is improving in all aspects of organ failure, but remains catecholamine dependent A thorough examination and review of...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... 2004, of portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distribution ... syndrome), including carbamazepine, phenytoin, phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks of ... pre-dialysis and 2–3 hrs following the post-dialysis dose There is a case report in which lithium levels were maintained in the therapeutic range by intraperitoneal administration of lithium during continuous...
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Báo cáo y học: " Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"
... provide written informed consent Use of other natural health products, including glucosamine and chondroitin, one month prior to study and during the study, other than multivitamin and mineral supplements ... unwilling to stop taking other medications for the treatment of OA Any other condition that, in the opinion of the investigator, would adversely affect the subject's ability to complete the study or ... capsule contains 375 mg of glucosamine HCl (USP Grade) and 300 mg of chondroitin sulfate (USP Grade) The subjects were instructed to take two G+C capsules in the morning and two in the evening for...
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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... tissue and gastrointestinal tract, as well as other sites, are known to reach the CNS to effect changes in feeding behavior and energy expenditure Thus, insulin, leptin and ghrelin, as well as other ... closely and rapidly with reciprocal changes in the levels of the orexigenic and anorectic Signaling mediators in the treatment of obesity neuropeptide expression in the hypothalamus [22] Thus an increase ... explored further Other areas of the brain have also been shown to regulate feeding via AMPK [35,36] Of interest is the extensive use of fructose as a sweetener in the human diet [37] Glucose and fructose...
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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
... at each phase of the cell cycle by various complexes of cell-cycle-related molecules, including cyclins, cyclin-dependent kinases, their inhibitors and the retinoblastoma protein (RB), as well ... calorie intake induces expression of RMI1 and E2Fs in adipocytes, and these changes in expression are expected to increase a positive interaction between the molecules The increased expression of ... recruitment of preadipocytes [12], suggesting that these cyclin-dependent kinase inhibitors are important in the regulation of adipocyte number The S-phase kinase-associated protein (Skp)1–CullinF-box...
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báo cáo hóa học:" Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement" doc
... screening including erythrocyte sedimenta- Page of tion rate and C-reactive protein was normal Plain radiographs revealed areas of periprosthetic osteolysis in the femur and the tibia, and a ... image of the left knee showing the introducing cannula and simultaneous venting of the medial tibial condylar cyst Discussion When dealing with massive periprosthetic osteolysis the aims of surgery ... years later In January 2005 the patient began to develop similar medial pain and swelling in the left knee A bone scan showed increased activity in the medial femoral condyle indicating possible...
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Báo cáo y học: "Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review" pdf
... Annals of General Psychiatry 2009, 8:16 the treatment of acute mania, the approval of quetiapine and the olanzapine-fluoxetine combination against acute bipolar depression and the approval of olanzapine, ... dose at the end of the study was 15.5 mg daily The results suggest that in weeks to and then again at week there is a significant reduction in the MADRS scores in the aripiprazole group in comparison ... which included 66 of the 67 patients who completed the 26-week period Unfortunately only 12 of them (5 in the placebo group and in the aripiprazole group) completed the 74-week treatment period The...
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Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx
... effective in the treatment of psychotic major depression, and the switch to sertraline worsened the psychotic symptoms in the patient The mechanisms underlying the opposite effects of these two ... fluvoxamine binds to sigma-1 receptors in the intact human brain at therapeutic doses [25], suggesting that sigma-1 receptors are involved in the active mechanisms of fluvoxamine [19] Interestingly, ... that activation of the dopaminergic system by the inhibition of dopamine transporter may be involved in the mechanism of unwanted effects (deterioration of psychosis) of sertarline in this case,...
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Báo cáo khoa học: "Factors of influence upon overall survival in the treatment of intracranial MPNSTs. Review of the literature and report of a case" doc
... contributions All of the authors have been involved in drafting this paper and have read and approved the final manuscript KG conceived the idea of the paper, reported the case, performed the literature ... concerning radiotherapy and followed up the patient at his out-patient clinic AK was the radiologist performing the preoperative and postoperative CT and MRI scans and wrote the part of the paper ... radiotherapy and conventional fractionation while minimising the risks of RT-inducing brain injury like radiation necrosis and cognitive decline The optimal radiation dose has not yet been defined We...
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Báo cáo khoa học: "Helical tomotherapy in the treatment of pediatric malignancies: a preliminary report of feasibility and acute toxicitty" doc
... HT at the Tomotherapy Unit of the Grupo IMO in the context of multidisciplinary national and international treatment protocols All the patients were treated with curative intent, including those ... to the Tomotherapy treatment planning system (Tomotherapy Inc., Madison, WI) to perform inverse treatment planning The planning goal was to deliver the prescription dose to at least 95% of the ... treatment time was composed of time required for patient set-up and anesthesia inside the treatment room, time of MVCT acquisition, time of review/match and applying couch correction inside the...
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Báo cáo khoa học: " Intensity modulated radiotherapy (IMRT) in the treatment of children and Adolescents - a single institution''''s experience and a review of the literature" pps
... treatment of the children HB is responsible for the anaesthesia management of the children PH is responsible for the clinical treatment of the children as head of the division of radiation oncology in ... helical tomotherapy have the potential of selectively sparing the thyroid gland and breast tissue in craniospinal irradiation The number of children treated with IMRT and the hard evidence for the benefit ... percent of the IMRT Group had grade or hearing loss, compared to 64% of the conventional-RT group The sparing of the hearing apparatus is of special importance since several modern combined chemotherapy...
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Báo cáo khoa học: " Neoadjuvant radiochemotherapy in the treatment of fixed and semi-fixed rectal tumors. Analysis of results and prognostic factors" pptx
... according to the actuarial method of Kaplan and Meier [24] The calculation of OS, DFS and LC was performed from the date of diagnosis to the date of the event Survival was measured from the date of ... sphincter-sparing surgery is nowadays the main subject of controversy One of the most important controversies is whether the degree of downstaging warrants this type of surgery [1] Results of the ... treatment was temporarily interrupted The decision of performing this weekly CT schedule instead of during the first and last week of RT course had the objective of maximize the radiation effect Adjuvant...
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Báo cáo khoa học: " Inverse planned stereotactic intensity modulated radiotherapy (IMRT) in the treatment of incompletely and completely resected adenoid cystic carcinomas of the head and neck: initial clinical results and toxicity of treatment" potx
... cystic carcinomas of the head and neck are a unique kind of tumour deriving from cells of the major and minor salivary glands, they account for 25% of all malignant salivary gland tumours in different ... studies using photon beams for the treatment of ACCs IBRT and IMRT with the tested dose concept is feasible and results in a promising clinical outcome justifying further investigations Furthermore ... by slice on the treatment planning CTs using the 3D-conformal radiotherapy planning system VIRTUOS which was developed at the dkfz An image fusion of the treatment planning CT and the MRI scan...
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báo cáo khoa học: "R-CHOP versus R-CVP in the treatment of follicular lymphoma: a meta-analysis and critical appraisal of current literature" ppt
... stages III and IV) Combining the studies, there were 439 patients, and over 98% of these were late-stage Treatment efficacy The main characteristics of the four studies are shown in table 3, ... of those met all inclusion criteria as studies of frontline or re -treatment Two of those four met the criteria for the first analysis (frontline treatment alone) Outcome The primary goal of the ... (53%) or R-CHOP (63%) The international PRIMA study testing the efficacy of maintenance therapy by rituximab may provide important data in the field of the best induction in patients with follicular...
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Báo cáo y học: " Clinical and economic ramifications of switching antipsychotics in the treatment of schizophreniab" pptx
... we assessed the proportion of patients receiving the service, the rate of use and rate of admissions, the time to first use of the service, and the annual health care cost, in terms of total health ... antipsychotic within 14 days of discontinuation of the initial therapy Data on the occurrence of acute-care service use, the time to the use of such services, and total-care and acute-care service ... hospitalization/day treatment, crisis services, and any acute-care services; as well as the total duration (in days) of each of these services and the rate of admissions to the facilities providing them Total and...
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Báo cáo y học: "The cost of relapse and the predictors of relapse in the treatment of schizophrenia" potx
... participated in the design of the study and the analytical plan DEF participated in the design of the study, the analytical plan, the interpretation of the results, and assisted in drafting the manuscript ... manuscript DS and ES participated in the design of the study, the analytical plan, the interpretation of the results, and assisted in drafting the manuscript They were also involved in preparing the resource ... costing data of US-SCAP XP performed the expanded statistical analyses, participated in the design of the study, the analytical plan, and the interpretation of the results RRC assisted with the interpretation...
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Báo cáo y học: "Cetuximab in the treatment of metastatic mucoepidermoid carcinoma of the salivary glands: A case report and review of literature" doc
... contributions SG was involved in the conceptual design of this study, in the clinical management of the patient, and in the writing and editing of the manuscript VA was involved in the Page of (page number ... scan examinations VDF was involved in the clinical management and contributed to the writing and editing of the manuscript GM supervised the entire treatment, provided financial and administrative ... obtained from the patient at the beginning of each treatment A separate institutional informed consent was obtained at the first visit, with regard to the treatment of personal data and use in...
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