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anatomy and physiology of the human heart pdf

Báo cáo khoa học: Arg143 and Lys192 of the human mast cell chymase mediate the preference for acidic amino acids in position P2¢ of substrates pdf

Báo cáo khoa học: Arg143 and Lys192 of the human mast cell chymase mediate the preference for acidic amino acids in position P2¢ of substrates pdf

Báo cáo khoa học

... of nine random amino acids, followedby a His6-tag in the C-terminus of capsid protein 10.Thereby, the phages display a random nonamer ontheir surface, and by interactions of the His6-tag the phages ... dis-tributed along the surfaces of the body. They are fre-quently found in the mucosa of the airways and intestine, in connective tissue of the skin, and aroundblood vessels and nerves. Upon ... number of poten-tial substrates during the screening of the full human proteome. This highlights the importance of factorsother than the extended cleavage specificity in deter-mining whether...
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Tài liệu Báo cáo khoa học: Topology, tinkering and evolution of the human transcription factor network doc

Tài liệu Báo cáo khoa học: Topology, tinkering and evolution of the human transcription factor network doc

Báo cáo khoa học

... compares the studied network withrandomized versions of it with the same size and degree dis-tribution. The so-called Z-score quantifies the differencebetween the studied network and an ensemble of ... analysis of the topological modules of the Fig. 3(labelled A–G) shows that they include structural and ⁄or functional features. Table 3 summarizes the main structural and functional features of thesegroups. ... functions, and topologi-cal features retain functionality and phylogeny. How-ever, the nature of the connections between thesefactors needs to be understood at the level of the pro-tein domain. The...
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Tài liệu Ownership of Mutual Funds, Shareholder Sentiment, and Use of the Internet, 2011 pdf

Tài liệu Ownership of Mutual Funds, Shareholder Sentiment, and Use of the Internet, 2011 pdf

Quỹ đầu tư

... telephone with the member of the household who was the sole or co-decisionmaker most knowledgeable about the household’s savings and investments. The standard error for the 2011 sample of households ... 353750525232Age of head of household11 Age is based on the age of the sole or co-decisionmaker for household saving and investing.2 For the complete time series of data from 1994 through ... U.S. households3Age of head of household11 Age is based on the age of the sole or co-decisionmaker for household saving and investing.2 For the complete time series of data from 1994 through...
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Tài liệu Ownership of Mutual Funds, Shareholder Sentiment, and Use of the Internet, 2012 pdf

Tài liệu Ownership of Mutual Funds, Shareholder Sentiment, and Use of the Internet, 2012 pdf

Quỹ đầu tư

... conducted over the telephone with the member of the household who was the sole or co-decisionmaker most knowledgeable about the household’s savings and investments. The standard error for the 2012 ... in the appendix. 12 See FigureA10 in the appendix.13 Some of the variation in the mutual fund favorability rating across the age groups is affected by differences in the frequency of the ... Sentiment, and Use of the Internet, 2012.” ICI Research Perspective 18, no. 6 (November). Available at www.ici.org /pdf/ per18-06 .pdf. Ownership of Mutual Funds, Shareholder Sentiment, and Use of the...
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Báo cáo Y học: Trehalose-phosphate synthase of Mycobacterium tuberculosis Cloning, expression and properties of the recombinant enzyme pdf

Báo cáo Y học: Trehalose-phosphate synthase of Mycobacterium tuberculosis Cloning, expression and properties of the recombinant enzyme pdf

Báo cáo khoa học

... isexpressed as the amount of trehalose-P synthesized in nmolÆmin)1 .The insert shows the Lineweaver–Burk plot of the data.Table 2. Comparison of the effect of heparin on recombinant and native TPS ... wascompared to the amount of NAD+produced (nmol) in the coupled assay, as an indirect measure of the amount of trehalose-P synthesized. However, for most of the studiesdescribed here, the anthrone ... constants for TPS The effect of substrate concentration on the activity of the TPS was determined as shown in Figs 6 and 7. Fig. 6 shows the effect of increasing concentrations of either UDP–glucose...
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Báo cáo khoa học: Expression of the Pycnoporus cinnabarinus laccase gene in Aspergillus niger and characterization of the recombinant enzyme pdf

Báo cáo khoa học: Expression of the Pycnoporus cinnabarinus laccase gene in Aspergillus niger and characterization of the recombinant enzyme pdf

Báo cáo khoa học

... activity (%)pHFig. 8. Effect of the pH on the activity of the purified laccase. pH in the range of 2.5–8 were tested with 500 lMABTS (d )and1 7lM of syringaldazine ( j) as the su bstrate.Sd 194 ... was 0.5% of the molecular mass of t he native laccase and and 10% for the recombinant l accase. I n the heterologous production of the P. cinnabarinus lac case in P. past oris [14] or the T. villosa ... are indicated the name of the primers u sed for amplification of the laccase cDNA and addition of cloning sites, recipient Aspergillus expression vector and restriction sites used i n the final cloning...
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Báo cáo Y học: Puri®cation and characterization of the human adenosine A2a receptor functionally expressed in Escherichia coli doc

Báo cáo Y học: Puri®cation and characterization of the human adenosine A2a receptor functionally expressed in Escherichia coli doc

Báo cáo khoa học

... temperature and using high concentrations of the weak antagonisttheophylline combined with low ¯ow rates. The ®nal ion-exchange step allowed removal of theophylline, and areduction of volume and detergent ... corresponds to the N-terminus of the m ature maltose-binding protein. Binding of the fusion protein to the IMAC gel in buffer containing50 mMimidazole indicates the presence of the C-terminalhistidine ... achieved.Ligand binding studies The quanti®cation of interactions with speci®c ligandsallows the structural integrity and homogeneity of a puri®edreceptor p rotein to be judged. The M-A2aTr316-H10...
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Rheological heterogeneity, mechanical anisotropy and deformation of the continental lithosphere pdf

Rheological heterogeneity, mechanical anisotropy and deformation of the continental lithosphere pdf

Kĩ thuật Viễn thông

... rooting of the fault into the asthenosphere and the interaction between the fault kinematics and the deformation of the asthenosphere due to plate motion remains open. Modified fromTeyssier and Tikoff ... rifting of the lithosphere (Wernicke, 1985). The relative thinning of the mantle (Ž) and of the crust (þ) varies across the rift and may result in the development of a stiff heterogeneity below the ... cold, thick, and consequently stiff lithosphere. On the other hand, riftingmay also modify the thermal structure of the lithosphere. Depending on the relative stretching of the crust and uppermantle,...
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Báo cáo Y học: Cloning, chromosomal localization and characterization of the murine mucin gene orthologous to human MUC4 pdf

Báo cáo Y học: Cloning, chromosomal localization and characterization of the murine mucin gene orthologous to human MUC4 pdf

Báo cáo khoa học

... transcript of apredicted size of  13 kb. Both human MUC4 and mouseMuc4 genes are virtually identical in terms of the class of introns, the exon number and size of exons. The sizes of the 24 mouse ... mappingexperiments. The last exon is composed of a codingsequence of 193 bp and of an untranslated region of atleast 131 bp. The size of the 24 introns ranges from 79 bp toabout 16 kb. The size of the largest ... obtained and studiedbut their analysis showed that they did not contain the central region or the 5¢ end of the gene. The cosmid clonecontaining the longest part of the new gene was namedCAR1 and...
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Báo cáo khoa học: Alanine screening of the intracellular loops of the human bradykinin B2 receptor – effects on receptor maintenance, G protein activation and internalization pdf

Báo cáo khoa học: Alanine screening of the intracellular loops of the human bradykinin B2 receptor – effects on receptor maintenance, G protein activation and internalization pdf

Báo cáo khoa học

... expres-sion of the constructs under the control of the CMV promoter; filledcolumns, HA-tagged constructs under the control of the weakerPminpromoter. (B) Immunoblot of B2Rwt, mutant 2 ⁄ 1 and the ... throughchanges in the overall structure of the receptor. Thus,these data demonstrate the connection between the structure of ICLs and that of the binding site, implyingreciprocally that changes at the binding ... depend on the cell type and the receptor expression levels. Although the processes of signaling and regulation of human B2R are, in general, fairly well understood, the knowl-edge of the molecular...
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Báo cáo khoa học: Constitutive expression of the human peroxiredoxin V gene contributes to protection of the genome from oxidative DNA lesions and to suppression of transcription of noncoding DNA pdf

Báo cáo khoa học: Constitutive expression of the human peroxiredoxin V gene contributes to protection of the genome from oxidative DNA lesions and to suppression of transcription of noncoding DNA pdf

Báo cáo khoa học

... Constitutive expression of the human peroxiredoxin Vgene contributes to protection of the genome fromoxidative DNA lesions and to suppression of transcription of noncoding DNAAndrey Kropotov1,2,3, ... bars)shows the results of analysis of 8-oxoG in the control and KD-1 cells. In the KD-1 cells, the concentration of endogenous 8-oxoG was significantly increased,indicating that PRDX5 contributed to the ... cellsdecreases formation of 8-oxoG in mitochondrial DNA[20], but the role of this protein in protecting nuclearDNA from oxidation in human cells and the mecha-nisms of regulation of the PRDX5 gene are...
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Báo cáo khoa học: Thioredoxin reductase from the malaria mosquito Anopheles gambiae Comparisons with the orthologous enzymes of Plasmodium falciparum and the human host pdf

Báo cáo khoa học: Thioredoxin reductase from the malaria mosquito Anopheles gambiae Comparisons with the orthologous enzymes of Plasmodium falciparum and the human host pdf

Báo cáo khoa học

... [34] between the fruit fly and the mosquito, not only the basic principles of redox metabolism and the genomicorganization of the TrxR gene, but also the mechanisticpeculiarities of these orthologous ... reaction of the cata-lytic cycle, of course, represents the net reaction catalyzed byTrxR.Discussion The isolation and characterization of A. gambiae TrxRcontributes to the understanding of the ... support the assumption that the substitution of the Trx system for GR, as well as the mechanistic particularities of the TrxR, are a commonprinciple in dipteran insects. In the context of the malarialsystem,...
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