analysis of cellular immune responses in cancer vaccine trials
Báo cáo khoa học: "Perioperative immune responses in cancer patients undergoing digestive surgeries" pptx
Ngày tải lên :
09/08/2014, 04:21
... suggesting that the elevation of IL-4 production during an ongoing immune response to tumor can down-regulate Th1 cytokine production Therefore, in gastrointestinal cancer patients, the initial ... equal volume of 4% formaldehyde fixative After washing and incubating with PBS/BSA/saponin for 10 min, cells were incubated with for 30 min, respectively Results were analyzed using the XL/XL-MCL ... different surgical procedures, and the clinical significance of the surgery-induced shift in the Th1/ Th2 balance The present findings confirm the findings of Decker et al., [10] who demonstrated...
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Báo cáo y học: " HIV-1 sub-type C chimaeric VLPs boost cellular immune responses in mice" potx
Ngày tải lên :
11/08/2014, 08:21
... Journal of Immune Based Therapies and Vaccines 2010, 8:7 http://www.jibtherapies.com/content/8/1/7 Page of Research Centre of the National Institutes of Health, Bethesda, Maryland, USA) in place of ... Therapies and Vaccines 2010, 8:7 http://www.jibtherapies.com/content/8/1/7 Page of Figure Use of a mixture of GagRT and GagTN VLPs as vaccine boosts BALB/c mice were vaccinated with the DNA vaccine pVRCgrttnC ... GagTN are used in mice in a DNA vaccine prime/VLP boost vaccination regimen [12] Novel results presented here include the induction of predominantly specific CD4+ cells producing IFN-g and IL-2...
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Báo cáo y học: "hytol-based novel adjuvants in vaccine formulation: 2. assessment of efficacy in the induction of protective immune responses to lethal bacterial infections in mice" ppsx
Ngày tải lên :
11/08/2014, 10:23
... passive infusion of immune responses induced in competent individuals Since most fatal nosocomial infection is caused by E coli and S aureus, it will be of interest to develop IgG-enriched vaccines ... adjuvants immunized Isotypic with of humoral immune responses in mice Isotypic profiles of humoral immune responses in mice immunized with bacterial vaccine formulated in different adjuvants Sera for ... adjuvant potentials of phytol and PHIS-01 in augmenting efficacy of vaccines against the common infectious agents S aureus and E coli Our vaccine formulations contain heat-inactivated bacteria...
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Cellular immune responses of dengue patients in singapore
Ngày tải lên :
03/10/2015, 11:36
... illness presenting early in the course of infection This collaborative study involving several institutions in Singapore examines viral, clinical, host-specific, and epidemiological aspects of early ... participates in innate immune functions As such, NK cells serve as a first line of defense against a broad spectrum of pathogens including viruses by clearing the virus during acute infections, ... to the lack of both in vitro and in vivo animal disease models and the complicated interplay of viral and host factors The bite of an infected mosquito inoculates DENV into the skin Infection is...
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Báo cáo hóa học: " Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early-stage breast cancer" pot
Ngày tải lên :
18/06/2014, 16:20
... based on areas of the raw spectra, averaging of technical repeats, binning of neighboring points to reduce data complexity, removal of the spectral area below baseline and normalization of the total ... identifying subgroups of patients with different patterns of changes in intensities of spectral components in time (between samples B and C) In this analysis the procedure of unsupervised clustering ... question of detecting therapy-related changes in the mass profiles registered for blood samples collected from breast cancer patients SELDI-ToF analysis of the plasma proteome of breast cancer...
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Báo cáo hóa học: " Elicitation of protective immune responses using a bivalent H5N1 VLP vaccine" pot
Ngày tải lên :
20/06/2014, 01:20
... influenza A virus using a DNA vaccine expressing hemagglutinin-C3d fusion proteins Vaccine 2003, 21:902-914 Couch R: Seasonal inactivated influenza virus vaccine Vaccine 2008 in press Bright RA, ... process of mass production VLP-based vaccines are a promising, innovative technology for safe and efficacious vaccines against many viral diseases [5-10], including influenza viruses [4] VLP vaccines ... clades of H5N1 influenza In this study, we investigated the ability of a vaccine representing isolates from clade and clade of the H5N1 subtype of influenza to elicit protective antibodies against...
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Báo cáo hóa học: " Promotion of allergic immune responses by intranasally-administrated nanosilica particles in mice" pot
Ngày tải lên :
21/06/2014, 05:20
... Ab binding was minimized by incubating the plates with 4% blocking solution (Block Ace; Antigen-specific cytokine responses were evaluated by culturing the splenocytes (5 × 106 cells/well) in ... nanosilica particles can induce the production of antigen-specific Ab responses including antigen-specific Th2 allergic immune responses Antigen-specific cytokine responses of silica particles To ... many of the pathologic features of allergic immune diseases [15] Some reports have shown that intranasal or airway exposure to nanomaterials promotes allergic immune responses, indicating the immune- activating...
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Báo cáo hóa học: " Outage Analysis of Ultra-Wideband System in Lognormal Multipath Fading and Square-Shaped Cellular " ppt
Ngày tải lên :
22/06/2014, 22:20
... destination node Interfering node Desired link source node Desired link destination node Interfering node (a) (b) Desired link source node Desired link destination node Interfering node Desired link source ... desired cell incorporating the link of interest and intracell interference links Surrounding eight cells are divided into subgroups #1 (light grey) and #2 (dark grey), both including 50 50 50 ... node position in cell #2, the link distance PDF becomes Desired link source node Desired link destination node Cell #0 interfering node Cell #1 interfering node Cell #2 interfering node Figure...
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Báo cáo khoa học: " Enhancement of protective immune responses by oral vaccination with Saccharomyces cerevisiae expressing recombinant Actinobacillus pleuropneumoniae ApxIA or ApxIIA in mice" pptx
Ngày tải lên :
07/08/2014, 20:23
... mucosal immune system by interacting with intestinal epithelial cells in the presence of butyric acid, a metabolite produced by intestinal bacteria [29] In addition to the induction of a specific ... alternative vaccines, including oral vaccines, have been sought after [8,18] In addition, the induction of immune responses at remote mucosal effector sites through a common mucosal immune system ... during the immunization period, while those in the two control groups remained unchanged (Fig 3B) Changes in IgA-secreting cells in the lung and intestine The number of IgA-secreting cells in...
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Báo cáo khoa học: " A dosimetric analysis of respiration-gated radiotherapy in patients with stage III lung cancer" pptx
Ngày tải lên :
09/08/2014, 10:20
... isotropic margin of 1.0 cm for microscopic extension and set-up inaccuracies; (iii) PTVgating, consisting of the volume encompassing 3– GTVs in the gating window, plus an isotropic margin of 1.0 cm ... contouring critical structures Gross tumor volumes (GTVs) were contoured in each of the 10 phases of a 4DCT using standardized lung and mediastinal window level settings by one clinician in order ... respiratory gating, derived from calculating the displacement of the GTVgating within GTVall phases, and (iii) residual GTV mobility within gating windows, derived from displacement of the GTVsingle phase...
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Báo cáo y học: "Adoptive transfer of splenocytes to study cell-mediated immune responses in hepatitis C infection using HCV transgenic mice" pptx
Ngày tải lên :
13/08/2014, 13:20
... response IFN-g intracellular staining CD8+ CTL responses were assessed by measuring the mouse IFN-g production using intracellular staining The intracellular procedures were done according to Caltag ... understood Cellular immune responses play a critical role in liver damage during the clinical course of hepatitis C infection HCV-specific CD4+ T cells are involved in eradication of the virus in acute ... signaling, which may then lead to cell death [11] HCV core protein increases the expression of Fas ligand on the surface of liver-infiltrating T cells leading to the induction of hepatic inflammation...
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Functional analysis of metallothionein 2a isoform in breast cancer
Ngày tải lên :
14/09/2015, 14:08
... %) showing positive MT staining and only 22 cases (15.7 %) showing absence of MT staining in the nucleus The staining of MT was classified into two groups; presence or absence of MT staining and ... Tell-tale signs of breast cancer other than presence of lumps include thickening in an area of the breast, change in the size or shape of the breast, dimpling of the skin, change in shape of the nipple, ... SUMMARY Breast cancer is one of the most prevalent cancers in women worldwide The rate of breast cancer has been increasing rapidly Invasive ductal carcinoma makes up the bulk of all breast cancer cases...
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Mapping targets of immune responses in complete dengue viral genomes
Ngày tải lên :
10/11/2015, 12:27
... targets for vaccine formulation Immunogenic is defined as capable of producing an immune response 14 2.1.3 Targets of immune responses in dengue viral genome The principal targets of cellular immune ... have important implications for vaccine design The most important finding in this study is that by focusing on specific targets of immune responses in the context of individual HLA supertypes, the ... be, increasing and so is the number of dengue variant sequences in public databases Formulation of a vaccine against dengue variants is difficult and challenging because of the ever increasing...
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ANALYSIS OF HYDROXYL RADICAL GENERATION IN ADVANCED OXIDATION PROCESS -EFFECT OF HUMIC SUBSTANCES DURING OZONATION
Ngày tải lên :
05/09/2013, 08:40
... order to obtain the mathematical relation of enhancing parameters of 3-chlorophenol on OH radical generation during ozonation, the initial velocities in the mixture of various amounts of ozone with ... during ozonation (Han et al, unpublished results) In the present paper, we demonstrate the quantitative analysis of OH radical generation by using the electron spin resonance (ESR)/spin-trapping ... M)]) In the drinking water treatment, 1-1.5 ppm of ozone, which are corresponding to 20-30 µM, are generally used The initial velocities of OH radical generation at the 20 µM and 30 µM of ozone...
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Economic feasibility analysis of a wind farm in Caldas da Rainha, Portugal
Ngày tải lên :
05/09/2013, 14:59
... Taking into account the differences in values found in the economic and financial analysis of the wind power project and its costs, it is interesting to note the degree of interdependence of ... assessing of a wind farm as a manner of validating the indicators of attractiveness and risk of energy projects and analysis of production costs sensitivity analysis was done by considering the ... values of investments, revenues, operating costs, costs of major repairs and divestitures Table 12 shows the values of attractiveness indicators used in economic and financial analysis of the wind...
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Review and analysis of renewable energy perspectives in Serbia
Ngày tải lên :
05/09/2013, 16:10
... MoME - Ministry of Mining and Energy of Republic of Serbia Strategy of development of energy industry of Republic of Serbia until 2015, draft report, 2005 [6] EPS – Electric Power Industry of Serbia, ... Bosnia-Herzegovina - Renewable energy The Dutch Ministry of Economic Affairs, EVD – The Agency of International Business and Cooperation, 2009 [17] Ministry of Energy and Mining Renewable Energy in Serbia ... project partner in Serbia Mr Dejan Stojadinovic, Assistant Minister for RES, Ministry of Mining and Energy of the Republic of Serbia, whose helpful remarks and fruitful observations were invaluable...
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A discourse analysis of economic export contracts in english and vietnamese
Ngày tải lên :
26/11/2013, 13:26
... ensurance -Words in role of gerunds: the signing, the moving, the changing, the inspecting In Vietnamese official document, a good number of Vietnamese words of Chinese origin is used: kh i t (prosecute), ... FEATURES OF LAYOUT OF EECS IN ENGLISH AND VIETNAMESE 4.2.1 The Layout of EECs in English In general, an English EEC consists of three parts: the beginning, the body and the ending The beginning is ... type of discourse 2.3.3 Official Document Style In the view point of Gaperin [13, p.102] “There is a type of language special used to exchange information between those who involve in a business,...
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A discourse analysis of collective labour agreements in english and vietnamese
Ngày tải lên :
26/11/2013, 13:30
... frequencies of occurrence - Synthesizing, discussing the findings, and drawing conclusions - Suggesting some implications for teaching and learning as the analysis consisting of fifty samples in English ... implications for teaching and learning of English language as well as writing legal documents, especially of them is extremely important In Vietnam, with the increasing establishment of foreign companies, ... follows: The standard form of the beginning section of VCAs: 4.1.2.2 The Kinds of Articles in ECAs and VCAs Usually, the articles of collective agreements are divided into two parts: obligatory...
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A discourse analysis of college admissions essays in english
Ngày tải lên :
26/11/2013, 13:31
... overall picture of discourse analysis Most of their works equip us with insights to investigate language in use In Vietnam, linguists have joined in the trend of researching on discourse analysis as ... in use, Discourse analysis, has become a new area of language investigation since the early decades of the 20th century Arising out of a variety of disciplines, including linguistics, sociology, ... as for those interested in writing AdEs in English? 1.5 DEFINITION OF TERMS 1.6 SIGNIFICANCE OF THE STUDY Despite the critical role of the AdEs in the application process, this kind of essay seems...
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Tài liệu A Comparative Analysis of Individual Communication Processes in Small docx
Ngày tải lên :
09/12/2013, 16:15
... turn-taking and speaking time distribution In the following, the construct of turn-taking behaviors is reviewed Turn-taking is the ordering of moves that involve any organized interplay of speech acts ... turn-taking and speaking time in intercultural groups, the use of language and the second-language proficiency of the interlocutors are also likely to be relevant factors that influence the number of ... of turn taking and speaking time in group decisionmaking meetings As for Research Question 3, it first examines the impact of cultures on the distribution of turn-takings and speaking time Second,...
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