... process in terms of motion tweening Imagine that you want to create the motion of a ball starting from the top left of the Stage, moving tothe top right, then tothe bottom left, and finally tothe ... hints Some arethe ending shape hints for the first tween; others arethe beginning shape hints for the second tween or Insert a new keyframe adjacent tothe second keyframe, and begin adding ... state that we are using the names in an editorial fashion only andtothe benefit of the trademark owner with no intention of infringement of the trademark 987654321 Printed and bound inthe United...
... discourages themin applying technology in teaching writing They all admit that there are some constraints in applying process approach in teaching writing All of them want to have further training especially ... their writing skill All of the teachers (100%) believed that writing topics and exercises inthe textbook are interesting, relevant and varied However, 20% of them think thatthe topics are quite ... despite the fact that they are interesting enough such as describing the chart/ table or giving instruction As for students, most of them supposed thatthe topics inthe book are varied, effective and...
... Specifying interesting traffic for DDR Traffic must be defined as ‘interesting’ to cause the DDR interface to dialup the remote router For the moment, declare thatall IP traffic is interesting using ... erase and reload instructions at the end of this lab Perform those steps on all routers inthis lab assignment before continuing Step Configure the router Configure the following according tothe ... Please refer tothe chart at the end of the lab to correctly identify the interface identifiers to be used based on the equipment inthe lab The configuration output used inthis lab is produced...
... suggesting thatthe N-terminal portion of the protein containing the HA epitope was lost from these proteins by proteolysis To determine which of the RNF13 bands is the initial biosynthetic product, ... to bind to C-terminal vacuolar sorting determinants on tobacco chitinase and barley lectin [14], establishing thatin plants the PA domain can serve as a ligand-binding domain The best-characterized ... RING domains [33] We therefore investigated whether the RING domain inthe cytoplasmic half of RNF13 was capable of catalyzing polyubiquitination The cytosolic domain of RNF13D1–205 comprising...
... evident inthe medium (Fig 4B, lane 4), suggesting thatthe 80 kDa form was processed tothe 90 kDa form inthe Golgi apparatus before being released into the medium In support of this, this secretory ... conformation and assembles into the dimer structure; however, this catalytically active dimer further undergoes multiple cross-linkings among the dimers via the three cysteine residues inthe C-terminal ... The aggregation may lower the probability of TNSALP (1559delT) being segregated into COP II vesicles at the exit site from ER and therefore the mutant protein remains longer inthe lumen of the...
... tinh ống nghiệm chấp nhận rộng rãi số trẻ thụ tinh ống nghiệm lớn hết Năm 1986, ngàn trẻ em sinh sau thụ tinh ống nghiệm Bourn Hall: khoảng nửa tất em bé thụ tinh ống nghiệm giới Patrick Steptoe ... chẳng hạn sinh non , nhỏ Hơn nữa, theo dõi dài hạn trẻ em thụ tinh ống nghiệm chúng khỏe mạnh đứa trẻ khác Cho đến nay, khoảng Thụ tinh ống nghiệm bốn triệu trẻ em sinh nhờ thụ tinh ống nghiệm ... thập trứng Trứng gỡ bỏ laparoscopically Cấy Phôi thai trả tử cung phát triển thành bào thai Thụ tinh thể Tinh trùng cho vào đĩa nghiệm để thụ tinh cho trứng Thụ tinh ống nghiệm R.E Patrick làm việc...
... according tothe protein to which they are bound The ‘additional’ metal, M3, is present in SaSTP monomer C andin MtSTP In SaSTP allthe metals are Mg2+, whereas in MtSTP they are Mn2+ ions Arg13 and ... colored according tothe corresponding protein In SaSTP, the three metals are magnesium, the two metals in HsSTP are manganese andin TxSTP the two metals are calcium ions Thisandthe other figures ... found in MtSTP [9] In order to bind the metal ion, the flap domain moves away from the core andthe main chain conformation, especially that of the first helix, changes (Fig 2B) In MtSTP, in addition...
... a 50% loss in receptor content (Fig 2B) These results indicate that although ST binding sites were present inthe desensitized cells, ligand binding to these sites was not coupled to cGMP production, ... endocytosis and subsequent degradation The mechanisms involved inthis process are not yet identified It is possible thatthe activation of the cyclase domain of the 145 kDa form upon ligand binding ... of the intestine tothe guanylin/uroguanylin family of peptides [6], and also regulate GC-C signaling in extraintestinal tissues where GC-C and its ligands are expressed Acknowledgements This...
... cross-linkers react with the e-amino group of lysine residues and a-amino group from protein N-termini and, to a lesser extent, with the hydroxyl groups of serine, threonine and tyrosine residues ... cross-linking approaches allow: (a) the identification of surface areas involved in protein-protein interactions within protein complexes; (b) the characterization of the distance constraints within ... spanning residues 327–335 upon assembly of Ure2p into fibrils [33] Thus, the binding of Ssa1p inthe vicinity of this stretch interferes with Ure2p assembly into fibrils either because of a change in...
... one hand, households generally respond to declines in income by reducing both spending and saving, thereby generating changes in spending thatare smaller than the changes in income Andthe effects ... relative tothe size of the economy means that further substantial increases in debt would be especially risky inthis regard Therefore, eliminating or reducing the fiscal restraint scheduled to occur ... would allow for implementing them gradually while still limiting further increases in federal debt andthe corresponding negative consequences Therefore, although there are trade-offs in choosing...
... epithelium faces the subretinal space The inner and outer segments adjacent tothe OLM arethe most apical side of photoreceptors and extend into the subretinal space The OLM contains a so -called ... explained by the possible existence of a protein that mediates this interaction in 293 HEK cells by opening upthe structure of the molecules and allowing their intermolecular binding This mediator ... MPP5 at the OLM in human retina In between the retinal pigment epithelium andthe OLM of the retina resides the so -called subretinal space, which is a lumen The apical side of the retinal pigment...
... person was talking and acting through the written dialects Inthe novel Dracula, allthe diaries, of allthe individuals come together andinthe end, become one powerful, combination of descriptions, ... descriptions, facts, that represents a group as a whole andthe reader can feel as if they are part of the group and read, and think along with the characters Another thing dealing with the diary form ... if one person was telling the whole story, the reader would see and hear what the person telling the story heard and wrote down So using, the diary, Bram Stoker could make the reader "see" exactly...
... MAPK and triggers its dissociation from the cytoskeletal protein GKAP, therefore releasing it from the cytoskeleton into the cytoplasm [3] Our aim inthis study was to gain a better understanding ... the possible loss of E-cadherin or other protein(s) inthe hDlg complex under stressful conditions, andthe cortical cytoskeleton is therefore disrupted and hDlg released into the cytoplasm The ... sorbitol for 60 min, and then incubated for h in sorbitol-free medium (in the continued absence or presence of the inhibitor) Endogenous levels of hDlg were analysed by immunoblotting (lower) and...
... we cannot deny the weak interaction with PtdIns(3,4)P2 and PtdIns(4,5)P2 inthisin vitro assay system Amino-terminal part of PCaP1 as the site of binding to PtdInsPs In general, the polybasic ... PCaP1 interacts with PtdIns(3,5)P2 and PtdIns(3,4,5)P3, andthatthe N-terminal region is necessary and sufficient for specific binding with these two PtdInsPs The authentic peptide of the N-terminal ... protein con2268 tains a candidate for the myristoylation signal at the N-terminal region, and investigated this Biochemical analyses, including in vitro myristoylation, demonstrated the N-myristoylation...
... changes in these domains that altered the interaction between domains G2 and G4–6 [22] Therefore, we investigated the possibility of a pH sensitivity inthe interaction of the G4–6 domains with the ... been found to be necessary for the binding of actin [21] and similarly for the binding of tropomyosin [38] Solving the crystallographic solution of the whole gelsolin molecule in its inactive state ... state [4] led tothe Ôhelix latchÕ hypothesis [5] in which it is suggested thatthe C-terminal helix of gelsolin’s G6 domain binds G2 andthatthis contact is released upon the binding of calcium...
... the beginning” – bắt đầu Ví dụ “at the beginning of May” – vào đầu tháng Năm - Cần ý phân biệt "at the end of " "In the end" để tránh nhầm lẫn inthe end” = “finally” – cuối cùng, sau inthe end” ... lưu ý động từ to be (am, is, are) ” – chia dựa theo chủ ngữ “going to viết tắt “gonna” văn nói Nếu muốn chia dạng phủ định, ta thêm “not” vào sau động từ to be” - “She is going to – cô Trong ... at the end of the street (cuối đường), at the end of the book (cuối sách) Mạo từ the đứng trước từ bắt đầu nguyên âm “a, e, i, o, u”, the phát âm /ði/ - Trái nghĩa với “at the end” “at the...
... positively stained cells and 60 counts of thetotal number of cells; this resulted in 60 labeling indices per group The results are expressed as the median, the interquartile range (IQR), standard deviation ... of head and neck squamous epithelia and carcinomas ORL J Otorhinolaryngol Relat Spec 2005, 67:61-69 Kato T, Uzawa A, Ishihara K: Inhibitory effect of galectin-3 on the cytokine-inducing activity ... initiated and conducted the study, formulated the hypothesis, established and conducted the methods and analytic procedures, and wrote the manuscript PH formulated the hypothesis and interpreted the...
... further investigation Conclusion The data presented inthis paper show thatthe recTULV presents no real match tothe original cell adapted variant andthatthe lower fitness of the recombinant ... bases inthe minus-sense RNA Interestingly, in Puumala hantavirus, a hairpin-like structure formed by a highly conserved inverted repeat inthe 3'-noncoding region of the S segment seems to be involved ... predicted for the recombination "hot-spot" inthe plus- and minus- sense S RNA of TULV Hairpin-like Hairpin-like structures predicted for the recombination "hot-spot" inthe plus- and minus- sense...
... driven by the synthetic E/L promoter (black arrow inthe bottom line) The resulting virus was designated VV Δ F2L-gfp and contained a deletion in F2L corresponding to amino acids 11–129 of the open ... and a standard plaque reduction assay was used to evaluate the susceptibility of the dUTPase mutant andthe parent virus The mutant remained fully sensitive toall of the drugs tested including ... by the viral TK tothe monophosphate (N-MCT-MP) [12] This is significant since intracellular pools of dUMP and dTMP are predicted to be reduced inthe absence of the viral dUTPase Thus, the increased...
... contains a disrupted thymidine kinase gene due tothe M2 insert [10] This disruption has been shown to result in attenuation compared to its strain WR parent, yet the virus still causes disseminated ... IN, and a non-respiratory virus, a recombinant Western Reserve (WR) strain of vaccinia virus (VV) expressing the RSV M21 protein (VV-M2), which was administered either by theIN or ID route IN ... BALB/c mice to monitor CD8+ CTL responses tothe M2-1 protein expressed by RSV versus VV-M2 using a peptide, SYIGSINNI, from the M2-1 protein (amino acids 82 to 90) that is the immunodominant http://www.virologyj.com/content/5/1/105...