accreditation credentialling and granting of clinical privileges
báo cáo hóa học: " Relationship between the EQ-5D index and measures of clinical outcomes in selected studies of cardiovascular interventions" pot
Ngày tải lên :
18/06/2014, 19:20
... Boxplots of the EQ-5D index and other patient characteristics pretreatment and after treatment by study The figure shows boxplots of the raw baseline and post-treatment values of EQ-5D, SF-6D and ... Page of 14 (page number not for citation purposes) Health and Quality of Life Outcomes 2009, 7:96 http://www.hqlo.com/content/7/1/96 Table 1: Summary of studies used and disease/treatment group and ... cross-sectional study in a cohort of patients implanted with an ICD at one of two centres between 1991 and the end of 2001 Sixtynine percent of the patients that had an ICD implant - all of those still alive...
- 14
- 610
- 0
báo cáo khoa học: " Production and quality of clinical practice guidelines in Argentina (1994–2004): a cross-sectional study" pps
Ngày tải lên :
11/08/2014, 16:21
... hospital, or other details of clinical practice [2] The ultimate purpose of developing and using guidelines is to improve the quality of care provided, particularly in areas of clinical uncertainty ... Zealand and European countries Most of these countries have developed national programs for CPG production, dissemination and implementation in order to increase the effectiveness and quality of ... (GIN) [4] and the Appraisal of Guidelines for Research and Evaluation (AGREE) Research Trust [5] The need for harmonizing and systematizing guideline development and assessment was one of the most...
- 10
- 226
- 0
A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 1 ppsx
Ngày tải lên :
14/08/2014, 07:20
... Medical Evidence and the Law, New York: Norton CHAPTER CUT COSTS AND INCREASE PROFITS CLINICAL TRIALS Clinical trials consist of a randomized comparison over a fixed period of time of an intervention ... COSTS AND INCREASE PROFITS Chapter Guidelines THE PURPOSE OF THIS CHAPTER AND THIS TEXT is to provide you the manager with a set of guidelines for the successful design and conduct of clinical ... to the Design and Conduct of Clinical Trials, by Phillip I Good Copyright ©2006 John Wiley & Sons, Inc CHAPTER CUT COSTS AND INCREASE PROFITS had to carve out each letter by hand and cost their...
- 26
- 515
- 2
A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 2 pps
Ngày tải lên :
14/08/2014, 07:20
... rather than a proponent of any specific point of view And, of course, at least one member of the review committee should have a copy of the current ICH Good Clinical Practices in hand END POINTS Our ... Integrity and security of data To say nothing of investigators, investigational laboratories, safety and efficacy review committees, and patients 13 Don’t attribute this quote to me, Professor Deming and ... review of past clinical and preclinical experience with the present and related interventions is essential For example, suppose that extremely high doses of your new agent result in the presence of...
- 26
- 555
- 2
A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 3 pps
Ngày tải lên :
14/08/2014, 07:20
... sources of inaccuracy Problems in data management and a lack of clarity of the protocol and/ or case report forms were the primary offenders They pointed out that training and supervision of data ... matter of life and death? The Heart Protection Study and protection of clinical trial participants Control Clin Trials 24:501–505; 585–588 Moore T (1995) Deadly Medicine: Why Tens of Thousands of ... developments in medical clinical trials J Dent Res 83: Spec No C:C18–24 Ebi O (1997) Implementation of new Japanese GCP and the quality of clinical trials—from the standpoint of the pharmaceutical...
- 26
- 469
- 2
A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 4 potx
Ngày tải lên :
14/08/2014, 07:20
... format and organization of reports, for the format and contents of tables, and for the format and naming of files and directories The CTD provides for analysis of trial data, descriptions of manufacturing ... Nonclinical Overview 2.4 Clinical Overview 2.5 Nonclinical Written and Tabulated Summaries 2.6 Clinical Summary 2.7 Module Module Module Quality 3.1 T of C Nonclinical Study Reports 4.1 T of C Clinical ... encouraged The use of graphs and concise tables in the body of the text is encouraged The Clinical Overview should present the strengths and limitations of the development program and study results,...
- 26
- 494
- 2
A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 5 potx
Ngày tải lên :
14/08/2014, 07:20
... experiences of males and females, should be accompanied by a discussion of the statistical techniques employed and include measures of variability (23.2% ± 4.6%), of sample size (n = 323), and of statistical ... and software development is well under way Recruitment of physicians and the initial recruitment of patients should be brief and intense, concentrated in a few short weeks Ideally, training of ... (Efficacy) of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) Guideline for Industry: Structure and Content of Clinical...
- 26
- 604
- 2
A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 6 pdf
Ngày tải lên :
14/08/2014, 07:20
... part of the menu we can’t see Type and Verify The type and verify field (Fig 10.3) is used for two types of data: measurements and comments such as “Other risk factors include .” A set of bounds ... regardless of differences in time zones? SUPPORT IS ESSENTIAL “Electronic clinical trials put very few technology demands on a user, and sites are usually unaware of the complexity of the underlying ... arrival of hardware and software often leave programmers sitting on their hands Similar delays arise when CRMs aren’t available to answer questions Information concerning the impact of delays...
- 26
- 529
- 2
A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 7 pot
Ngày tải lên :
14/08/2014, 07:20
... location Standard practice is the cycle of (sometimes 5, and sometimes 7) Backups are made on the evenings of days 1, 2, and On the night of day 4, the backup of day is sent to a remote location and ... supply on hand? and then go over points to be covered with your investigators and site coordinators, the final field tests of your questionnaires, data entry software and hardware, and uniform ... project manager and production and supplies on hand continually matched to forecast needs LATE AND INCOMPLETE FORMS Late and incomplete forms are the major source of cost overruns and trial delays...
- 26
- 545
- 2
A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 8 pot
Ngày tải lên :
14/08/2014, 07:20
... of clinical trials Familiarity Too often, the choice of statistical method is determined on the basis of the technique that was used in the last set of clinical trials or the limited subset of ... comparison of urn designs for randomized clinical trials of K > treatments J Biopharm Stat 10:93–107 Lachin JM; Matts JP; Wei LJ (1988) Randomization in clinical trials: conclusions and recommendations ... beginning or submitting the results of a statistical analysis A copy of the 1996 IHS Guideline for the Format and Content of the Clinical and Statistical Sections of an Application may be downloaded...
- 26
- 504
- 2
A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 9 doc
Ngày tải lên :
14/08/2014, 07:20
... logarithms of the observations, computes the mean and standard error of the logarithms and determines a symmetric confidence interval One then takes the antilogarithms of the boundaries of the confidence ... Good P) (1981) Randomization in the analysis of experiments and clinical trials Am Lab 13:98–102 International Study of Infarct Survival Collaborative Group (1988) Randomized trial of intravenous ... kept track of every aspect of the trials: • • Were supplies of drugs/devices/biologics, forms, and sample collection kits always on hand when needed? Were computers in physician’s of ces and the...
- 26
- 517
- 2
A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 10 potx
Ngày tải lên :
14/08/2014, 07:20
... ease of formulating queries, 2) speed of retrieval of data, 3) ease of updating data, 4) ease of restructuring the database, and 5) ease of integrating other applications including data entry and ... man’s SAS, offers ease of use along with a large number of statistics A bootstrap subcommand provides bootstrap estimates of standard errors and confidence limits Thoroughly validated and has been ... Guide to the Design and Conduct of Clinical Trials, by Phillip I Good Copyright ©2006 John Wiley & Sons, Inc APPENDIX SOFTWARE 237 Oracle Clinical Has the standard features of Oracle Automatically...
- 23
- 643
- 2
Báo cáo y học: "Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia"
Ngày tải lên :
25/10/2012, 11:18
... yield of endoscopy in patients with IDA and to define predictive factors of gastrointestinal (GI) lesions causing IDA and identify clinical and biochemical variables that predict the outcome of ... endoscopic and radiographic Asymptomatic colonic and gastric carcinoma may present with IDA and exclusion of these conditions is of prime concern The upper endoscopic evaluation should include random ... presence of dyspeptic complaint and its severity calculated by presence of abdominal pain, abdominal pain with hungry and anxiety, abdominal distension, nausea, vomiting, poor appetite and symptoms of...
- 9
- 425
- 1
Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"
Ngày tải lên :
25/10/2012, 11:40
... comparative efficacy and tolerability of 5-Loxin® and Aflapin® in the treatment of OA of the knee Materials and Methods Study materials BE-30 (5-Loxin) is a novel Boswellia serrata extract standardized ... Hematological and biochemical evaluations For assessment of safety of 5-Loxin® and Aflaseveral parameters were evaluated in serum, urine and whole blood of all subjects at each visit of the study ... software to evaluate the efficacy of 5-Loxin® and Aflapin® in comparison with the placebo group in terms of improvement in pain and physical function scores at baseline and on days 7, 30, 60 and...
- 12
- 606
- 0
Báo cáo y học: " Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"
Ngày tải lên :
26/10/2012, 09:48
... common form of arthritis, and it is often associated with significant disability and an impaired quality of life Clinical and radiographic surveys have found that the prevalence of OA increases ... in treatment of arthritic pain in horses Clinical conditions (body weight, body temperature, respiration rate, and pulse rate), and liver (bilirubin, GGT, and ALP) and kidney (BUN and creatinine) ... coagulopathies, history of peptic ulceration and upper GI hemorrhage Uncontrolled hypertension History of congestive heart failure, history of allergic reaction to chicken and/ or eggs History of allergic...
- 10
- 706
- 0
Tài liệu Clinical presentation and outcome of patients diagnosed with active pulmonary tuberculosis in a large critical care unit docx
Ngày tải lên :
15/02/2014, 12:20
... morbidity and mortality of tuberculosis is the source of major medical and social problems, especially in developing countries It is ranked as the seventh highest cause of morbidity worldwide, and ... Clinician awareness of the symptomatology and contributory factors of the disease is vital Diagnoses may be challenged by atypical clinical presentations along with the lack of sensitive and rapid diagnostic ... morbidity and mortality It will be important to develop and utilize novel, more sensitive and specific tests Considering the serious impact of missed or delayed diagnoses and the risk of transmission...
- 6
- 506
- 0
KDIGO Clinical Practice Guideline for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) pdf
Ngày tải lên :
22/03/2014, 09:20
... frequency of assessment is based on the presence and persistence of identified abnormalities, the severity of abnormalities, all in the context of the degree and rate of change of GFR and the use of ... interpretation of biochemical and hormonal values in the diagnosis of CKD–MBD requires an understanding of assay type and precision, interassay variability, blood sample handling, and normal postprandial, ... suggestions and edits on the wording of recommendations, and on the use of specific grades for the strength of the recommendations and the quality of evidence The Work Group took on the primary role of...
- 140
- 777
- 1
Classification of colorectal cancer based on correlation of clinical, morphological and molecular features doc
Ngày tải lên :
22/03/2014, 17:20
... families, about half of 117 which met the Amsterdam criteria, a high proportion of both polyps and CRC showed mutation of BRAF and ⁄ or methylation of the CIMP marker MINT31 Many of the polyps were ... immunohistochemistry for MLH1] The glands to the left are normal and show nuclear expression of both MGMT and MLH1 The gland with features of serrated adenoma and the poorly differentiated adenocarcinoma ... and CRC as described above Molecular alterations occurring at the key transition from hyperplasia to dysplasia include loss of expression of MLH1 in group CRC and loss of expression of MGMT and...
- 18
- 679
- 0
Tuberculosis - Clinical diagnosis and management of tuberculosis, and measures for its prevention and control doc
Ngày tải lên :
22/03/2014, 18:20
... practice and resources, and to identify areas where these did not match the clinical need This collected information through a review of the epidemiology of TB in England and Wales, and a review of ... or TB, is one of man’s oldest foes and for centuries among the most feared One of the triumphs of modern medicine has been the development of vaccination and medication capable of combating this ... diagnosis of latent TB has been updated by the Short Clinical Guidelines team New 2011 guidance on the clinical diagnosis and management of tuberculosis (TB), and within NICE Grey bars in the right hand...
- 307
- 399
- 0
From Cancer Patient to Cancer Survivor - Lost in Transition: An American Society of Clinical Oncology and Institute of Medicine Symposium pot
Ngày tải lên :
22/03/2014, 20:21
... Professor of Medicine, Oncology and Blood and Marrow Transplantation, at Stanford University She is also the president of the American Society of Clinical Oncology, and a great friend to all of ... AMERICAN SOCIETY OF CLINICAL ONCOLOGY AND THE INSTITUTE OF MEDICINE Ellen Stovall, Vice Chair, Committee on Cancer Survivorship: Improving Care and Quality of Life; and President and CEO, National ... Head and Professor of Medicine and Health Policy and Professor of Pediatrics at George Washington University I am delighted to introduce them both here to you today INTRODUCTORY REMARKS Sandra...
- 196
- 280
- 0