aa pdgf ra signaling represses the stimulatory effect of tgfb on asma expression and tgfb releases asma from the pdgf a mediated suppressive effects
Báo cáo y học: " Inhibition of SOC/Ca2+/NFAT pathway is involved in the anti-proliferative effect of sildenafil on pulmonary artery smooth muscle cells" pps
... indicated that therapeutic effects (vasodilation/antiproliferation) of sildenafil was involved in inhibition of the SOC/Ca2+/NFAT pathway Additionally, activation PKG pathway by sildenafil and ... expres- sion (at the transcription and translation level) and attenuation of SOC -mediated Ca2+ influx may be the potential pathway mechanism involved in the anti-proliferative effect of sildenafil ... calcineurin activity and NFAT nuclear translocation NFAT nuclear translocation is involved in hypoxia-induced TRPC1 up-regulation and human PASMC proliferation The effects of a direct and specific...
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Báo cáo hóa học: " Research Article Nonlinear Synchronization for Automatic Learning of 3D Pose Variability in Human Motion Sequences M. Mozerov, I" pot
... found that each dimension on the PCA space describes a natural mode of variation of human motion Additionally, the main modes of variation of human gait are naturally represented by means of the ... tested for the walking action and is automatically learnt from the public CMU motion capture database As a result, we learnt the parameters of our action model which characterize the pose variability ... minimization with a weak constraint (the derivative of the synchronization path is constrained) works very well In our case the dimensionality of the signal is up to 37D and weak constraint does...
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Báo cáo khoa học: " Expression of pituitary adenylate cyclase activating polypeptide and its type I receptor mRNAs in human placenta" doc
... mechanism of PACAP in human placenta, the localization of PACAP and its PAC1 receptor in the same areas strongly suggest that PACAP may act as an autoregulator or pararegulator via its PAC1 receptor ... Results The present study showed the expression and distribution of PACAP and PAC1 receptor mRNAs in the human placenta at various gestations In situ hybridization revealed the expression of PACAP and ... determine the existence of PACAP and PAC1 receptor mRNAs in human placenta Our data showed the expression of PACAP and PAC1 receptor mRNAs in stroma cells of stem villi and terminal villi As gestation...
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báo cáo khoa học: "First-in-class, first-in-human phase I results of targeted agents: Highlights of the 2008 American Society of Clinical Oncology meeting" pot
... contributions AM collected and assembled the data, and participated in conception and design, data analysis and interpretation, and manuscript writing LS participated in conception and design, data analysis ... gemcitabine), and in combination with chemotherapy in melanoma patients Discussion Phase I trials of targeted agents represent the culmination of years of laboratory work and preclinical animal evaluations ... Kawamura H, Urata Y: Phase I trial of intratumoral administration of OBP-301, a novel telomerase-specific oncolytic virus, in patients with advanced solid cancer: Evaluation of biodistribution...
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Báo cáo y học: "CD4+ T cells spontaneously producing human immunodeficiency virus type I in breast milk from women with or without antiretroviral drugs" potx
... of human colostrum and milk I Distribution characteristics and concentrations of immunoglobulins at different times after the onset of lactation J Pediatr 1978, 92:546-549 Tuaillon E, Al Tabaa ... related to plasma HIV-1 load We assume that our observations reflect the particular dynamics of HIV-1 replication within the mammary gland and the existence of a functional reservoir probably ... had stopped ART at time of sampling and showed detectable HIV-1 plasma viral load Characterization of CD4+ T cells in breast milk As shown in one representative case (patient no 10), we characterized...
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Báo cáo y học: " Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IκBα and enhances HIV-1 replication in human T lymphocytes" ppsx
... carboxy-terminus of the polypeptide (325–551 aa) contains two transactivation domains, TA1 and TA2 (415–551 aa) The presence of several putative caspase cleavage sites has been indicated with discontinuous arrows ... cleavage of caspase-3 (Fig 4a) Although there was a clear correlation between activation of caspase-3 and the increase of nuclear ΔNH2p65, densitometric analysis of gel bands showed that there ... Luciferase expression was then analyzed in the whole protein extracts Internal control of transfection was carried out by co-transfection with pSV-β-Galactosidase vector and protein concentration was...
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Báo cáo y học: "Microarray study reveals that HIV-1 induces rapid type-I interferon-dependent p53 mRNA up-regulation in human primary CD4+ T cells" doc
... 5'-TGTTCAAAGCAGGCCCGAG-3' 5'-CGGAACTACGACGGTATCTGATC-3' 5'-AACCTCTACTTCTGCCTTGTCT-3' 5'-CGCCTCTCCTGAACGATACTC-3' 5'-GGAGAACCACCATAATTC-3' 5'-TCTTCCTATTCCTGAACC-3' Page of 14 (page number not for citation purposes) ... Garcia-Sastre A, Lee SW, Aaronson SA: Transcriptional role of p53 in interferon -mediated antiviral immunity J Exp Med 2008, 205(8):1929-1938 Yonezawa A, Morita R, Takaori-Kondo A, Kadowaki N, Kitawaki ... technologies are rapidly expanding our analytical power Among the technical innovations developed in the past few years, cDNA and oligonucleotide microarrays have revolutionized the way we look at and...
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Báo cáo y học: " Open Access Quantification of the virus-host interaction in human T lymphotropic virus I infection" pdf
... groups of similar rates of lysis Within each group the mean proviral load of the subjects with a high rate of Tax expression and the mean proviral load of subjects with a low rate of Tax expression ... that the association between Tax expression and HAM/ TSP is not simply because Tax expression acted as a surrogate for proviral load per se On the other hand, the association between proviral ... expression was calculated The difference between these two means is the "change in proviral load with an increased rate of Tax expression" and was plotted against the average rate of CTL lysis in that...
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Báo cáo y học: " Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity" pps
... 241 Baba H, Yamada Y, Mori N, Hayashibara T, Harasawa H, Tsuruda K, Sugahara K, Soda H, Takasaki Y, Tawara M, Hirakata Y, Tomonaga M, Kamihira S: Multiple gammac-receptor expression in adult ... Y, Hirakata Y, Tomonaga M, Sugahara K, Hayashi T, Dateki N, Harasawa H, Nakayama K: Aberrant expression of caspase cascade regulatory genes in adult T-cell leukaemia: survivin is an important ... 246 Yamada Y, Hatta Y, Murata K, Sugawara K, Ikeda S, Mine M, Maeda T, Hirakata Y, Kamihira S, Tsukasaki K, Ogawa S, Hirai H, Koeffler HP, Tomonaga M: Deletion of p15 and/ or p16 genes as a poor-prognosis...
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Cambridge.University.Press.Who.Believes.in.Human.Rights.Reflections.on.the.European.Convention.Oct.2006.pdf
... meaning of liberalism, however Utilitarianism and social democracy both belong to the liberal tradition and neither advocates a handsoff approach by the government See Crawford Brough MacPherson, ... 58, 67 Manickavasagam Suresh v Canada (Minister of Citizenship and Immigration) and Attorney General of Canada, 11 January 2002, Supreme Court of Canada 110 Marckx v Belgium (Application 6833/74) ... law on transsexualism ¨ Van Kuck ’s ‘normalization’ from the perspective of the natural and the protest schools Can we have human rights? The responses of the natural and protest scholars Can...
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Kogan.Page.Managing.Projects.in.Human.Resources.Training.and.Developement.Apr.2006.eBook-DDU.pdf
... financial prospects of the organization The demands of a project on the cash flow of an organization can have an impact on other areas of work unless the demand has been anticipated and provision ... Australia, Malaya, Slovakia and Russia This enables revision appropriate to the needs of the new context, but it needs time and funding Adaptation and contextualization increase the sense of ‘ownership’ ... the context of large, relatively stable bureaucratic and hierarchical organizational structures If a significant amount of an organization’s work is managed through project structures there are...
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Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... 5’-TGCCAGATTGTCAGCGAAAC-3; HMGN3 reverse 5’-TGCTCCACCAAAACCTGAACCAAAC-3 All primers were synthesized by MWG Biotech AG (Ebersberg, Germany) Samples were prepared in triplicate and real time PCR measurement ... investigation confirms the effect of ethanol at low concentration (1 mM) on the expression of genes involved in transcriptional and translational processes that are also associated with human hepatocellular ... low concentration of ethanol on genes involved in translational processes such as STAU2, a protein that facilitates the initiation of translation Based on the increased expression of staufen...
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SCARAB BEETLES IN HUMAN CULTURE
... to the larvae of Catharsius molossus (L.) (Scarabaeinae) being eaten in China The larvae, pupae, and adults of Scarabaeidae continue to be regularly eaten in many parts of Southeast Asia, although ... of the Sahara, has a diverse scarab fauna Some of these scarabs are also relatively large (e.g., Augosoma centaurus [Fabr.] and Oryctes spp.) (both Dynastinae), and yet I am unfamiliar with any ... (Scarabaeinae) and their larvae Actually the Thais themselves consume some scarabs, although it is not prevalent In Thailand, adults of Copris sp and Onthophagus sp (Scarabaeinae), as well as the adults...
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3D Videocommunication Algorithms concepts and real time systems in human centred communication
... us and to note that he comes within the actual range of our senses in the case of cinema of our sight and in radio of our hearing Before the arrival of photography and later of cinema, the plastic ... CINERAMA AND SENSORAMA 11 Figure 1.2 Cross-section of a panorama, consisting of: (A) entrance and box office, (B) darkened corridor and stairs, (C) observation platform, (D) umbrella-shaped roof, ... for the capture of range images are outlined The authors discuss limitations, accuracies and calibration aspects of these methods Chapter 17 Tracking and User Interface for Mixed Reality by Y Abdeljaoued,...
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ĐỀ ÔN THI HỌC KỲ I in ch hsNăm học 2009
... (C) Da vo th (C) bin lun theo m s nghim thc ca phng trỡnh : x + x = m Cõu II (2.0 im) Tỡnh giỏ tr ca biu thc : P = log 5.log 27.log 25 2 Chng minh rng : a a a 2 a a + a 2 a +a + a = (a> 0) ... chúp S.ABCD vi ỏy ABCD l hỡnh vuụng cú ng chộo BD = a Hai mt phng (SAB) v (SAD) cựng vuụng gúc vi ỏy Tớnh th tớch ca hỡnh chúp SBCD bit SA = a II PHN T CHN (3,0 im) Hc sinh chn (cõu IV .a, V .a hoc ... phng trỡnh tip tuyn ca (C) bit tip tuyn vuụng gúc vi ng thng x y = + 2010 Cõu II (2.0 im) a 1ữ 1 Chng minh rng : ( a >0 ) + 1 = 1 a + a +1 a4 + a8 +1 a a8 +1 a2 a4 +1 Tớnh giỏ tr biu...
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TRAFFICKING IN HUMAN BEINGS
... widespread corruption, to ferry Turkish, Iranian, Iraqi, Albanian and Afghan migrants into Europe for £5,000 a head A report from the International Organization for Migration says 120,000 women and ... Border Declaration Listen to the declaration of the two statesmen and report… Who said that they have agreed to an aggressive action plan? How will the passage of people and goods be between the two ... accessible and inexpensive through telecommunications advances, but the expansion of existing criminal networks is (10)…………… by rapid and enhanced contact-gathering and information exchange capacities...
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Introduction of Who Believes in Human Rights
... encompasses various strands – has a variety of answers on the question of whether the gap between human rights theory and practice is due to a conceptual or a practical failure Liberal and non-liberal ... meaning of liberalism, however Utilitarianism and social democracy both belong to the liberal tradition and neither advocates a handsoff approach by the government See Crawford Brough MacPherson, ... that such edicts were not fatwas in the traditional sense of the Islamic term and that Baxi’s terminology had the effect of associating bad practice with Islam and/ or the East By contrast, talking...
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Projects in human resources training and developement
... financial prospects of the organization The demands of a project on the cash flow of an organization can have an impact on other areas of work unless the demand has been anticipated and provision ... Australia, Malaya, Slovakia and Russia This enables revision appropriate to the needs of the new context, but it needs time and funding Adaptation and contextualization increase the sense of ‘ownership’ ... the context of large, relatively stable bureaucratic and hierarchical organizational structures If a significant amount of an organization’s work is managed through project structures there are...
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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in human malignancies and potential therapy pdf
... Anderson SA & Massague J (2004) Integration of Smad and forkhead pathways in Role of MLL in human malignancies 50 51 52 53 54 55 the control of neuroepithelial and glioblastoma cell proliferation ... directly activate transcription of the CDKN 1a ⁄ p21 gene, explaining why p53 was not necessary for the transcriptional activation of CDKN 1a ⁄ p21 It also explains the observations made by Wang and ... as the mammalian orthologue of the Trithorax protein in invertebrates [6] Disruption of this gene in invertebrates and vertebrates leads to homeotic transformation and nullalleles are incompatible...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25