a role in cognitive functions in mice and men
Báo cáo khoa học: "Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions" ppt
Ngày tải lên :
12/08/2014, 04:20
... analysis and review of the manuscript YN performed project planning, participated in the data analysis and helped to draft the manuscript All authors read and approved the final manuscript Weissman AM: ... AP-1 [41]; δ-adaptin, a marker for AP-3 [42] Both AP-1 and AP-3 localizes to TGN and endosomes, with AP-3 localizes more to endosomes [43] UL56 colocalized with both γadaptin and δ-adaptin, albeit ... suggests that the interaction of the two proteins is dynamic and transient Given that Nedd4 participates in many cellular trafficking activities including protein sorting and viral budding, UL56 can...
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báo cáo khoa học: " Co-expression and promoter content analyses assign a role in biotic and abiotic stress responses to plant natriuretic peptides" pptx
Ngày tải lên :
12/08/2014, 05:20
... Ishida J, Narusaka M, Fujita M, Nanjo T, Umezawa T, Kamiya A, Nakajima M, Enju A, Sakurai T, Satou M, Akiyama K, YamaguchiShinozaki K, Carninci P, Kawai J, Hayashizaki Y, Shinozaki K: Monitoring ... physiological role of AtPNP -A in A thaliana a T-DNA insertion mutant, that is available from SALK, could be used Phenotyping this mutant in response to SA-inducing abiotic and biotic stresses as well as ... documenting induction of AtPNP -A expression in SA-mediated natural developmental and stress activated processes which both culminate in cell death indicating that AtPNP -A may be involved in these...
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Báo cáo khoa học: Differential expression pattern of the novel serine⁄threonine kinase, STK33, in mice and men doc
Ngày tải lên :
16/03/2014, 23:20
... standard procedures [47] Accordingly, template for the production of sense RNA was amplified with the primers 5¢-CAGAGATGCATAATACGACTCACTATAGG GAGAAACCCAGAAAGTGATGAG-3¢ and 5¢-TAGAA CTAAGCGAGCATG-3¢, ... CTAAGCGAGCATG-3¢, whereas the template for the production of the antisense strand was amplified using the primers 5¢-CAGAGATGCATAATACGACTCACTATAG GGAGATAGAACTAAGCGAGCATG-3¢ and 5¢-AACC CAGAAAGTGATGAG-3¢ The ... our data and expression databases Hsa STK33 Organ ⁄ tissue Testis Lung Fetal lung Heart Fetal heart Heart’s interv septum Brain Fetal brain Pituitary gland Ovary Kidney Stomach Pancreas Trachea...
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Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf
Ngày tải lên :
18/02/2014, 04:20
... with a full-length furin cDNA, were permeabilized and stained with polyclonal antibodies against furin and GRASP55 Arrows show examples of membrane compartment containing GRASP55 and furin Scale ... containing insulin, transferrin and selenium supplements (Sigma-Aldrich) and the cells were incubated at 37 °C for a further 24 h Cell supernatants were harvested and analyzed by gelatin zymography, ... colleagues [35] GRASP55F in pCDNA3.1 Zeo+ contained a C-terminal FLAG tag Full-length GRASP55, GRASP55 PDZ1 (amino acids 1–107), GRASP55 PDZ2 (amino acids 84–172) and GRASP55 region (amino acids...
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Báo cáo hóa học: " Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment" pptx
Ngày tải lên :
18/06/2014, 16:20
... treatment significantly attenuated some alterations (i.e increased levels of aspartate transaminase, alanine transaminase, alkaline phosphatase, acid phosphatase, lactate dehydrogenase, gamma-glutamyltransferase, ... (TIRdomain-containing adapter-inducing interferon-b) joining the RIG-I/MDA5 pathway In the other pathway, TLR7 senses single-strand HCV RNA and via the MyD88 adaptor protein activates IRAK4/IRAK1 These kinases ... prodrug Int J Cancer 2009, 124(11):2520-7 90 Jagan S, Ramakrishnan G, Anandakumar P, Kamaraj S, Devaki T: Antiproliferative potential of gallic acid against diethylnitrosamineinduced rat hepatocellular...
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báo cáo sinh học:" The role of nurses and midwives in polio eradication and measles control activities: a survey in Sudan and Zambia" pdf
Ngày tải lên :
18/06/2014, 17:20
... advocacy, social mobilization, training, implementation, supervision, monitoring and evaluation) and the same proportion was involved in AFP surveillance On the other hand, in Zambia, nurses and ... proposal, discussions, data analysis and review of the article SH, ETAES and HM were involved in data collection, discussion and review of article All authors have read and approved the final manuscript ... and 18.1% in Sudan and Zambia, respectively, as an important factor for improving work performance Best practices in SIAs for polio and measles Nurses and midwives reported that they played a...
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PHYTOCHEMICALS – A GLOBAL PERSPECTIVE OF THEIR ROLE IN NUTRITION AND HEALTH potx
Ngày tải lên :
28/06/2014, 11:20
... Silveira, Antonio Marcos E Bezerra, Luzia Kalyne A M Leal and Glauce Socorro B Viana Chapter 18 General Introduction on Family Asteracea 375 Maha Aboul Ela, Abdalla El-Lakany and Mohamad Ali Hijazi ... characteristics, analytical challenges in their isolation and characterization, and the undertaking of basic and clinical researches to evaluate their biological activities both in animal and human health ... rutin, naringin , hesperidin and chlorogenic (Fig 4) 2.5 Saponins The term saponin is derived from Saponaria vaccaria (Quillaja saponaria), a plant, which abounds in saponins and was once used as...
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Báo cáo y học: "The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis" doc
Ngày tải lên :
09/08/2014, 10:23
... Therapy Vol 10 No Alten et al ACR response criteria were evaluated at baseline and on days 8, 15, 22, 29 and 43 by the investigator, and at baseline and day 43 by a blinded observer at each site ... safety and pharmacokinetic assessments, and a formal end of study was reached at day 113 Investigators were free to change treatment after day 43 as they deemed necessary Statistical analyses Statistical ... Almost all rheumatologists prefer to administer a TNF blocker rather than anakinra as a first biologic agent to treat RA patients, concordant with a recent consensus statement, and national and...
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Báo cáo y học: "Endogenous and exogenous stem cells: a role in lung repair and use in airway tissue engineering and transplantation" pdf
Ngày tải lên :
10/08/2014, 05:21
... Komura M, Komura H, Kanamori Y, Tanaka Y, Suzuki K, Sugiyama M, Nakahara S, Kawashima H, Hatanaka A, Hoshi K, Ikada Y, Tabata Y, Iwanaka T: An animal model study for tissue-engineered trachea fabricated ... cells that have been used or have a potential to be applied in lung regeneration; and analyze current strategies in tracheal bioengineering and transplantation Endogenous and exogenous stem and progenitor ... engineers should pay special attention to the fabrication of biologically active scaffolds and matrices capable of fulfilling natural properties of the airway ECM, for example, by maintaining and...
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Báo cáo y học: "Effect of a structurally modified human granulocyte colony stimulating factor, G-CSFa, on leukopenia in mice and monkeys" docx
Ngày tải lên :
10/08/2014, 21:23
... acquisition and analysis data interpretation as well as drafting manuscript YQ carried out protein purification experiments and was involved in data acquisition, analysis and interpretation WJ conducted ... conducted in vitro experiments including protein purification and analysis WD was involved in the analysis and interpretation of data as well as manuscript preparation The authors read and approved ... conducted in compliance with the Guidelines for Animal Experimentation issued by the Chinese Association for Laboratory Animal Science and the Standards Relating to the Care and Management of Experimental...
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a role for the endosomal snare complex and tethers in autophagy
Ngày tải lên :
22/12/2014, 21:44
... evolutionary conserved and adaptive catabolic process that plays a central role in maintaining intracellular homeostasis and thereby cellular health The term ‘autophagy’ directly translates to ... investigated a role for endosomal trafficking and autophagy in C.elegans post-embryonic development and identified a role for these pathways in the clearance of the pre-moult increase in intracellular ... proteasome-mediated degradation Ubiquitination can also signal substrate proteins for lysosome-mediated degradation and coordinate protein localisation and protein activation status (Katzmann et al., 2002;...
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A cross cultural study of using hedges in refusing a request in english and vietnamese
Ngày tải lên :
14/12/2013, 00:41
... legal, and literary It can be said that connotation can be seen as an additional meaning to denotation In general, both connotation and denotation are important to determine word meaning in a ... obtain these aims, data and sources are collected and gathered through reading and selecting numerous English and Vietnamese idiomatic expressions Then, the author categorizes and analyzes data ... as a lion As fierce as a tiger As slippery as an eel As slow as a tortoise As slow as a snail As stink as a polecat As thick as ants As wet as a drowned rat Like water off a duck’s back To fight...
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Tài liệu Báo cáo khoa học: Differentiation stage-dependent preferred uptake of basolateral (systemic) glutamine into Caco-2 cells results in its accumulation in proteins with a role in cell–cell interaction pptx
Ngày tải lên :
20/02/2014, 01:20
... Glutamine incorporation in Caco-2 proteins determining the relative uptake of glutamine; (b) by searching for changes in the intestinal proteome; and (c) by examining glutamine incorporation into ... cytoplasmic proteins that can bind to the membrane surface in response to elevations in intracellular calcium [45] Annexin A2 is an F-actin binding protein and participates in the formation of ... FBS, and a defined amount of glutamine, as detailed below Measurement of L-glutamine uptake by Caco-2 cells Glutamine uptake in Caco-2 cells was initiated by adding experimental medium containing...
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Tài liệu The Clyde Mystery a Study in Forgeries and Folklore doc
Ngày tải lên :
21/02/2014, 14:20
... which appear to be painted, not incised I argued, on the contrary, that things of similar appearance, at Mas d'Azil: in Central Australia: and in Caithness, need not have had the same meaning and ... the "manufacturers" did know, apparently, that perforated and inscribed, or uninscribed tablets and plaques of shale and schist and slate and gas coal were found in America, France, Russia, and ... wits coincided fairly well, in Portugal and in Scotland, as earlier, at Volosova and Breonio In Portugalia, a Portuguese archaeological magazine, edited by Don Ricardo Severe, appeared an article...
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Peptidylarginine deiminase (PAD) is a mouse cortical granule protein that plays a role in preimplantation embryonic development docx
Ngày tải lên :
05/03/2014, 17:20
... (SignalP V2.0 and TargetP V1.0) [35-37] were used to determine that a putative signal peptide and a cleavage site exist in ePAD and AAH53724 (an egg and embryo abundant peptidylarginine deiminase), ... (red) and ABL2 (green) A and D show the LCA labeling in the zona pellucida (arrowhead) B and E show ABL2 labeling on the plasma membranes and in the subcortical region (arrow) of blastomeres G and ... their assistance in obtaining Figures and 9, and Norton Kitagawa for his invaluable advice in tandem mass spectrometric protein identification Finally, we would like to thank Dr Bradley Hyman and...
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the auditors’ role in detecting and preventing fraud
Ngày tải lên :
13/03/2014, 14:20
... fraud that causes a material misstatement in the financial statements In additional, Auditing Standard (ASA 240) continues by saying that there are two types of intentional misstatements relating ... challenged If audited financial statements are materially misleading and contain material frauds, and if investors and creditors use those statements for financial decision making, investors and ... in particular, as the main purpose of financial audit In recent years, in the Statement of Auditing Standards (SAS) No 99 entitled Consideration of Fraud in a Financial Statement Audit, it was...
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Interest Rate Policy in Egypt - Its Role in Stabilization and Adjustment pdf
Ngày tải lên :
15/03/2014, 14:20
... Andras Inotai April1991 D Ballantyne 37947 Wendy Takacs E Michalopoulos 1991 April WPS644 Trade Payments and Arrangements Constantine Tarr in Post-CMEA Eastern Central David and Europe M.Colinet ... Aidto Africa April1991 S King-Watson 33730 and Nanak Kakwani WPS647 Growth Rates Aggregate Welare:An International Comparison April1991 B Rosa 33751 PREWorkingPaperSeries Contact AAhob Dfra and WPS648 ... NOMINAL RETURN 19 TAX TABLE 3, GROWTH OF MONETARY AGGREGATESAND INFLATION 21 TABLE 4, REAL RETURN ON A STANDARD PROJECT TABLE 5, MAXIMUM PAYABLE INTEREST RATE AND REAL RETURN ON INVESTMENTS...
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You Are a Brand!: In Person and Online, How Smart People Brand Themselves For Business Success
Ngày tải lên :
15/03/2014, 23:28
... sales, and marketing skills, and by having a valuable network of business and personal contacts I am also going to talk about success in a larger sense, in terms of self-actualization— being who ... meant to be Branding is a great tool for both, because it makes you an active partner in your business and in your life destiny You Are a Brand! will teach you selfbranding strategies and career ... was a handicap “Why does an Asian art scholar want to be in advertising?” was the refrain But persistence does pay off One ad agency interpreted my background as “creative,” and I had a foot in...
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Báo cáo khoa học: Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans docx
Ngày tải lên :
16/03/2014, 23:20
... 5¢-TATCTAGATCATTTATCTCTGGTGAGCA C-3¢ 5¢-GCGTCGACG AATTCTATGAGCCTCCGGCAG-3¢ 5¢-CCGGATCCTCAAGAAAATCTGGTCACAGC-3¢ 5¢-AAGTCGACAATGGCCTCGCG CTGGTGGCGGTG-3¢ 5¢-GGCGGATCCTCATTTATCTCT TGTGAGTACAATTTC-3¢ 5¢-ACAAAGCTTATGGCCTCGCGCTGGTGGCGGTG-3¢ ... 5¢-CCGGAATTCTCATTTATCTCTTGT GAGTACAATTTC-3¢ 5¢-GCGGAT CCATGGCCTCGCGCTGGTGGCGGTG-3¢ 5¢- TATCTAGATCATTTATCTCTTGTGAGTACAATTTC-3¢ 5¢-CTGGATCCAT GAACTTTCGGCAGCTGCTGT-3¢ 5¢-TTCCCGGGTCATGAAAATCTGGTCACAGC-3¢ ... Okada K, Tanaka K, Nakagawa T, Kawamukai M & Matsuda H (1997) Cloning and functional expression of a novel geranylgeranyl pyrophosphate synthase gene from Arabidopsis thaliana in Escherichia...
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