... data of TESPA The spectral data of FT-IR, 1H NMR and 13C NMR and MS for TESPA Received: 10 May 2011 Accepted: August 2011 Published: August 2011 References Kuech TF, Mawst LJ: Nanofabrication of ... the reaction of cyanuric chloride, 3-aminopropyltriethoxy silane (APTES), and NaSH according to the strategy described in the Figure The stirring tetrahydrofuran (THF) solution of cyanuric chloride ... the TESPA SAM The thickness of the TESPA SAM was about 2.8 nm The results of XPS for the TESPA SAM before and after Pd catalyzation are shown in Figure The presence of Sn3p, Sn3d, Pd3s, Pd3p,...
... study of an experimental intrapleural adesion model revealed three points: (a) The anti -adhesion effects of Prevadh® was achieved following thoracotomy, and length ofadhesion and intensity ofadhesion ... Mean length ofadhesion in Group A and B were 3.0±2.2 and 10.0±2.0, respectively, while it was 0.0 cm in Group C Mean intensity ofadhesion scores in the Group C (n=8) 4 8 Length ofadhesion (mm) ... intercostal space and intrapleural adhesions were analyzed macroscopically (Figure 1C and 1D) Adhesions were scored as shown below: A) Length of adhesion: The length ofadhesion before the first thoracotomy...
... The number of pmoles of cathepsin L were determined by titration of the active site with E-64 as described previously [29] The concentration of heterodimeric cathepsin L was 64–65% of that calculated ... Purification of cathepsin L-like protease The cathepsin L-like protease (CLP) in embryos of the brine shrimp, A franciscana was purified using a modification of a published method [24] Fifty grams of fully ... One unit of protease activity was defined as the release of micromole of amino peptide per minute from the substrate at pH 4.0 and 40 °C CL assays were carried out using a modified method of Barrett...
... cleavage of both FAK (106 ± 12% of intact FAK) and p130Cas (91 ± 11% of intact p130Cas) proteins Mevalonate alone had no effect on the integrity of focal adhesion proteins (101 ± 11% of intact ... domain of integrins Maintenance of cell–matrix contact is an important cell survival factor and the loss of cell–matrix and cell– cell contact is a characteristic feature of apoptosis [16] Focal adhesion ... intracellular effects of lovastatin treatment in rat brain neuroblasts, i.e., activation of caspases and the cleavage of focal adhesion proteins and PKCd The elucidation of intracellular mechanisms...
... concentration (25 lm) of LPC (Fig 1D) Contribution of NF-jB to LPC-induced activation of AMs To define the molecular mechanism of LPC-induced upregulation of AMs, the influence of LPC on NF-jB activation ... expression of vascular cell adhesion molecule-1 (VCAM-1) [7], intercellular adhesion molecule-1 [8] and P-selectin [9] both in vitro and in vivo However, the intracellular signal pathway of these ... phosphorylation of cytosolic jB inhibitor (IjBa) (Fig 2A), implying the activation of NF-jB by LPC To uncover the interaction between LPC-induced activation of NF-jB and upregulation of AMs, NF-jB...
... spotty RHEED pattern of sample (a) and (b) independent of InAs coverage introducing the effect of IF bonds on tc The GaAs (311) B surface has two type of atom positions, including twofold coordinated ... been conducted to check the effect of substrate orientation on tc [18, 19] Besides, it had been found that the effect ofinterfacial (IF) bonds can influence tc of the noncommon anion heteroepitaxy ... example: tc of this system was much thinner when the IF bonds consisted of In–Sb bonds rather than the Ga–As bonds [20, 21] This is due to additional IF strain offered by the higher atom sizeof In...
... dissociation of the adherens junction, permitting the dying cell to first detach from its neighbors (loss of E-cadherin), and then shrink (loss of α-catenin, cleaved Arm and retraction of actin microfilaments) ... Caspase-mediated cleavage of β-catenin promotes changes in cell adhesion and cell shape (a) Drosophila; (b) mammals Adherens junctions are composed ofadhesion complexes of E-cadherin (gray bars), ... that modifications of other components of the adherens junction complex (cleavage of E-cadherin has been reported in mammals [10]) contribute to the sequential dissociation of the junction β-Catenin...
... through suppression of intercellular adhesion molecule-1 Marzo, M E and Montalban, X Immunological profile of patients with primary progressive multiple sclerosis: Expression ofadhesion molecules ... Salzman, A L and Szabo, C Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NF-kappa B activation J FASEB 1998, 12, 685-693 ... findings of this study suggest that melatonin has an anti-inflammatory effect on EAE, caused by suppression of ICAM-1 and possibly by induction of NK cells production Although we found amelioration of...
... experimental models of inflammatory arthritis and the role of various adhesion molecules in human RA are still poorly understood The aim of the present study was to investigate the role of JAM-C in arthritis ... Committee of the Geneva University School of Medicine and by the Geneva Veterinarian Office Antigen-induced arthritis Mice were injected intradermally at the base of the tail with 100 μg of methylated ... injection of 100 μg of mBSA in incomplete Freund's adjuvant (Becton Dickinson and Company) was given at the base of the tail On day 21, arthritis was induced by intra-articular injection of 100 μg of...
... headpiece of the integrin heterodimers has been shown in crystal structures of αVβ3 [4,5] and αIIbβ3 [6] The binding site is composed of the β-propeller domain of the α subunit and the I-like domain of ... extracellular ligand binding back to the inside of the cell Much of our current knowledge of the myriad of functions attributed to ligand binding of a particular αβ pair comes from gene knockout ... extensions of plasma membrane) [15,19] In this manner, the affinity of an integrin and its valence in binding ligands such as intercellular adhesion molecule-1 (ICAM-1) regulate the extent of outside-in...
... Mode mix of exponential law in terms of potential energy Φ 91 Figure 3.13 Mode mix of exponential law in terms of normal traction Tn 92 Figure 3.14 Mode mix of exponential law in terms of tangential ... 3.15 Mode mix of PPR model in terms of potential energy Φ 95 Figure 3.16 Mode mix of PPR model in terms of normal traction Tn 95 Figure 3.17 Mode mix of PPR model in terms of tangential ... tt xxii Area Width of specimen Degree of damage Effective damage Elastic modulus Elastic modulus of steel Effective elastic modulus of concrete Secant modulus of elasticity of concrete Shear flexibility...
... SIMULATION OF CELL ADHESION AND DETACHMENT SUN LU (B Eng., FDU China) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF MATERIALS SCIENCE AND ENGINEERING NATIONAL UNIVERSITY OF ... cell adhesion 32 Figure 3.2 Schematic of vesicle adhesion mediated by the diffusion of the receptors and the binding of the receptor-ligand pairs 35 Figure 3.3 Variation of receptor ... models of cell adhesions were established from the aspects of two scientific disciplines The first is based on the mechanics of the membrane peeling test [15, 16, 17], in which the index of adhesion...
... Table of Contents Preface i Acknowledgements iii Table of Contents iv Summary viii List of Tables x List of Figures xii List of Symbols xix Chapter 1: Introduction 1.1 Overview of the Interfacial ... Correlation Studies on the BD/Si System 75 4.2 Mechanics ofInterfacialAdhesion 78 4.3 Curvature of the Crack Front 88 v 4.4 Determination ofInterfacialAdhesion 94 4.4.1 Elastic Modulus and Hardness ... adhesion However, the mechanics ofinterfacialadhesion is a rather complicated subject This thesis develops a simple way to measure the interfacialadhesionof thin film/substrate structure...
... middle of th wedge im m he mpression), and the FE ESEM plane view (Fig.4.4(a)) sho only e ows a central cra at this lo ack oad Fig F 4.3: Cr ross-section views o 120° wedge indenta nal of ations...
... debonding [7,8] To characterize the interfacialadhesion properties (e.g interfacial energy and interfacial strength), the interfacial cracking pattern is of particular interest The wedge and ... the crack-propagation process 4.2 Mechanics ofInterfacialAdhesion The fracture and failure of thin film/substrate systems can occur in a number of patterns, such as surface crack, channeling, ... The effects of l/t ratio on the interfacial toughness measurement will be discussed in Section 4.4.3 81 Chapter Fig 4.9: Configuration of cracks during the steady state propagation of interfacial...
... plan ne-view ima of delam age minated area on 500nm BD film A ninthm order polyn o nomial func ction is fit tted to the crack fron in order to determ nt r mine the curvature of the crack f c ... Curvature of interfaci crack front determ ial fr mined for t BD film with the ms thickness t anging from 100 to 100 m 00nm [2] 90 Chapter C Fig F 4.16: FESEM plan ne-view ima ages of the wedge ... tionship bet tween the cu urvature of crack front and the f t film thickne As can be seen i Fig.4.16( for a B film ≤ 100 nm th f ess n in (a), BD hick, the interfacial c i crack front is very...
... test 152 Chapter environments in terms of the slope of the curve and time of each stage Table 6.1 summarizes the slopes of the curves and the time durations of the each stage obtained from the load-holding ... * Courtesy of Ms Zhu Jing, PhD student of Associate Prof Dr Zeng Kaiyang 160 Chapter Section 7.2 presents the calculations of the interfacial toughness of the RuO2/Si system, using the wedge ... for the determination of the interfacial mechanical properties 5.3 Conclusions From the comparison of the simulation and experimentally obtained P-h curves before the onset of delamination, the...
... List of test cases with variation of the parameters 109 7.4 Residuals for an increasing number of iteration steps N 113 ix 68 LIST OF TABLES x List of Figures 3.1 Illustration of the ... Residuals in the u velocity as a function of the number of SR steps.117 7.9 Divergence of the velocity as a function of the number of SR steps.117 LIST OF FIGURES xiv Chapter Introduction Background ... multi-processing • Simulation of flows in an extended, wider range of Reynolds and Bond numbers for large, realistic ratios of the density and viscosity of the fluids: – Simulation of air bubbles rising...
... continuous growth of polyaniline on a platinum surface 42 STUDY OF ELECTRODE REACTIONS AND INTERFACIAL PROPERTIES require the establishment of the proper baseline For neighboring peaks (of a mixture), ... extracellular environment of the brain The good temporal and chemical resolutions of such in vivo cyclic voltammetric experiments offer improved understanding of the chemistry of the brain These repetitive ... function of the conductivity and chemical nature of the substrate, as well as of the tip–substrate distance The images thus obtained offer valuable insights into the microdistribution of the electrochemical...
... bonds between NH of Thr5 and CO of Arg2, as well as NH of Arg2 and CO of Thr5 Structure of cyclic hexapeptides – cYT peptide The NMR data of the cYT peptide were indicative of its flexible nature ... topologies of the turn region mimic those of rat CD2 Structure of cyclic hexapeptides – cEL peptide The chemical shifts of amide resonances of peptide cEL were well dispersed over a region of 1.2 ... constant of most of the amide protons was in the range of 6–8 Hz, suggestive of rapidly interconverting conformers that coexist in solution The temperature coefficients of chemical shift of amides...