6cancers other than breast cancerbreast cancer whose etiology is influenced by the estrogen receptorestrogen receptor c srcc src and her family members
The Management of Community-Acquired Pneumonia in Infants and Children Older Than 3 Months of Age: Clinical Practice Guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America pot
... Hospital Medicine, and the Society of Critical Care Medicine The guidelines were reviewed and approved by the PIDS Clinical Affairs Committee, the IDSA SPGC, the Council of the PIDS, and the Board ... beyond the endotracheal tube tip The inner catheter is then extended cm further and the protective plug expelled, allowing the brush to be advanced another 1-2 cm, and then retracted into the sheath ... antimicrobial therapy for CAP? VIII How should the clinician follow up the child with CAP for the expected response to therapy? Adjunctive Surgical and Non–Anti-infective Therapy for Pediatric CAP...
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Tài liệu Screening for Breast Cancer: Systematic Evidence Review Update for the U. S. Preventive Services Task Force doc
... invasive cancers are preceded by screen-detectable DCIS, and that the chance of DCIS progressing to clinically apparent disease is 90% Estimates for overdiagnosis were 3% of the total breast cancer ... individual’s risk and it is unclear how to apply these models to screening.27 Breast Cancer Screening Oregon Evidence-based Practice Center Current Clinical Practice Screening Breast cancer has a known ... cancer cases, with a 10% higher incidence in the screened group (7% for invasive cancer) 15 years after discontinuing screening.106 Breast Cancer Screening 21 Oregon Evidence-based Practice Center...
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Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine pdf
... human cancers Many cancers seem to be inherently resistant to chemotherapy and apoptosis and this has been attributed to the inactivation of p53 [31] The successful treatment of p53-deficient ... anticancer treatment regimens including chemotherapy and radiotherapy DENSPM and other polyamine analogues are presently undergoing Phase I and Phase II clinical evaluations in the US In L56Br -C1 ... Implications and concepts of polyamine–nucleic acid interactions J Cell Biochem 46, 37–47 27 Basu, H.S & Marton, L.J (1995) Biological and therapeutic implications of the effects of polyamines on chromatin...
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Báo cáo khoa học: Thiamin diphosphate in biological chemistry: new aspects of thiamin metabolism, especially triphosphate derivatives acting other than as cofactors pdf
... organisms In Escherichia coli and other Enterobacteriaceae, ThMP may be phosphorylated to the cofactor ThDP by a thiamin-phosphate kinase (ThMP + ATP « ThDP + ADP; EC 2.7.4.16) In most bacteria and ... Although they appear to be distinct from membrane-associated ATPases, their specificity for ThTP is not established Thiamin metabolism and thiamin phosphates and their catalytic efficiency could not ... thermocellum was recently found to hydrolyze inorganic triphosphate with a much higher catalytic efficiency than ATP [62] There was no adenylyl cyclase activity It is not known whether any of these enzymes...
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Báo cáo toán học: " Breast cancer screening in France: results of the EDIFICE survey" ppsx
... a personal history of cancer (N=105) were excluded from analysis because actual experience of cancer might affect cancer screening perceptions Therefore, the whole subject sample included 504 ... department of France) and their medical practice regarding screening of cancer (breast, colorectal, prostate, and lung cancer) , especially perceptions on screening methods, level of screening counselling, ... Quantitative data were described by the means and standard deviations (SD) and categorical data by the numbers in each category and corresponding percentages Comparison of distribution according to women...
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Báo cáo toán học: "Iodine Alters Gene Expression in the MCF7 Breast Cancer Cell Line: Evidence for an Anti-Estrogen Effect of Iodine" doc
... importance of the CYP1A1/CYP1B1 ratio in-vivo is evident in the increased presence of 4-OH-E2 in breast cancer tissue compared to non breast cancer controls [44] However, the regulation and interplay ... through its direct interactions with breast cancer cells One proposed mechanism by which iodine may influence breast physiology and cancer progression is through an interaction with estrogen pathways ... S, Cooksley CS Incidence of breast carcinoma in women with thyroid carcinoma Cancer 1999, 85:696-705 Eskin BA Dietary iodine and cancer risk Lancet 1976, 2:807-808 Eskin BA, Grotkowski CE, Connolly...
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Báo cáo y học: " Breast conserving surgery with preservation of the nipple-areola complex as a feasible and safe approach in male breast cancer: a case report" pptx
... were more than 0.8 cm The patient had four cycles of chemotherapy (Doxorubicin 100 mg and Cyclophosphamide 1000 mg) and adjuvant chest wall radiotherapy (50 gray in 25 fractions), which he tolerated ... of the circulat- Conclusion Despite limited indications and lack of evidence about the safety and efficacy of BCS with nipple preservation in men with breast cancer, it is a feasible approach ... axillary node clearance (ANC) [2,3,6] Despite the lack of firm evidence about the safety of SNB, increasingly there is an acceptance of the technique and its use [2,6] Radiation therapy seems...
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Báo cáo y học: "Hyperglycemia may alter cytokine production and phagocytosis by means other than hyperosmotic stress" pdf
... Critical Care Vol 12 No Wade cytokine response and the absence of a consistent attenuation of the response with insulin suggest that factors other than hyperosmolality and hypertonicity ... Otto and colleagues increased the glucose concentrations from 100 mg/dL to 250, 500, and 1,000 mg/dL Theoretically, this would increase plasma osmolality by 8, 22, and 50 mOsm/kg, respectively ... hyperglycemia, suggesting an alternate function other than hyperosmolality In addition, Otto and colleagues found hyperglycemia to reduce phagocytosis and oxidative burst in human granulocytes This...
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Dual activation of estrogen receptor a and aryl hydrocarbon receptor by the prenylflavone, icaritin restrict breast cancer cell growth and destabilize estrogen receptor a protein
... to test the effect of estrogen plus progestin therapy in postmenopausal hormone therapy and recurrence of breast cancer Table shows the risk of breast cancer recurrence in breast cancer survivors ... done by Collaborative Group on Hormonal Factors in Breast Cancer found that the risk of breast cancer decreased with the number of child births Each child birth decreased the risk of breast cancer ... Another important issue is the dosage of phytoestrogen This is because, it is found that the effect of genistein on breast cancer is dose dependent, with genistein stimulating breast cancer cell...
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EFFECTS OF INHIBITING THE MAMMALIAN TARGET OF RAPAMYCIN (MTOR) PATHWAY AND TELOMERASE IN BREAST CANCER CELLS
... another breast cancer cell type was purchased from ATCC and cultured in the same way as the other two breast cancer cells MCF-10A (Clontech, U.S.A.), immortalised normal breast epithelial cell ... therapeutic efficacy of breast cancers Additionally, the study hopes to unravel novel mechanisms by which cancer cells may regulate the complex mTOR circuitry and telomerase by as yet uncharacterised ... in breast cancer cells, and yield enhanced anticancer therapeutic efficacy, the objectives of the study are to: Validate breast cancer cells as a model to study the dual inhibition of mTOR and...
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Language Teaching Strategies and Techniques Used to Support Students Learning in a Language other than Their Mother Tounge
... Baccalaureate (IB) programme in a language other than their mother tongue To enable learners to fully participate in both the academic and social aspects of school life, educators need to recognize ... Teacher One Teacher Two Teacher Three Male 21-30 No Yes Female 20-30 No Female 51-60 26 Female 31-40 Female Teacher Four Teacher Five Teacher Six Teacher Seven Teacher Eight Teacher Nine Teacher ... in their speech long before they have full understanding of them” (Cameron 2001:73) Another strategy teachers used to check vocabulary understanding was to review and recycle previously discussed...
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Tài liệu The Teredo Protocol: Tunneling Past Network Security and Other Security Implications pptx
... relay source routing” section lists another Consider the case where a Teredo packet reaches a Teredo client (and is accepted) and the encapsulated IPv6 packet contains a Routing header The Routing ... that matches the client’s records is the only way to guarantee that an incoming packet is accepted (RFC 4380 section 5.2.3) Were either of these not the case (there is no trusted entry or the relay ... the client’s NAT to allow packets to reach the client However, a relay must be located before the communication can occur The following two subsections describe how this is accomplished for the...
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Tài liệu Cancer Pain Management: A perspective from the British Pain Society, supported by the Association for Palliative Medicine and the Royal College of General Practitioners docx
... Focus and Purpose The focus of this discussion document is on the patient with cancer pain The purpose of this document is: • To highlight the importance of recognising cancer related pain and ... consultant) • A chartered clinical psychologist or BABCP registered cognitive behavioural therapist • A physiotherapist (state registered) Other health professionals, such as occupational therapists, nurses ... area to another, which is the clinical scenario Combining radiotherapy with pharmacological and non-pharmacological management is generally recognised as the most effective treatment in this setting...
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Tài liệu Helping Children When a Family Member Has Cancer ppt
... informed and connected 20 www.cancercare.org Resources CancerCare 800-813-HOPE (4673) www.cancercare.org American Cancer Society 800-227-2345 www .cancer. org Kids Konnected 800-899-2866 www.kidskonnected.org ... sibling’s cancer and how it will affect the family isn’t easy, but it is necessary This CancerCare Connect® booklet can help It includes tips for talking with children about a family member’s cancer and ... germs Let them know they can’t catch cancer like a cold Tell them you can hug and kiss each other just like always Don’t be surprised if a child between the ages of and is mainly concerned about...
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Tài liệu Báo cáo khoa học: The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis ppt
... to the nucleus constitutively The APP ICD must form a complex with the nuclear adaptor Fe65 and the histone acetyltransferase Tip60 in order to target to the nucleus [61,62] Other ICDs function ... Technologies (Coralville, IA, USA), Invitrogen, and the Nucleic Acids Core Facility, UNC-CH Automated sequencing was performed at the UNC-CH Genome Analysis Facility Bacterial expression and purification ... participate in pancreatic cancer development [21] We show that RNF13 is synthesized as an endosomal integral membrane protein rather than a soluble nuclear protein, consistent with other members...
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Tài liệu Báo cáo khoa học: Identification of GAS-dependent interferon-sensitive target genes whose transcription is STAT2-dependent but ISGF3-independent doc
... Although the preferential GAS element for the STAT2–1 heterodimer is ATTTCCCGGAAA [18], the STAT2–1 complex can also bind to the GAS elements within the promoters of both IRF1 (ATTTCCCCGAAA) and FccRI ... within the carboxy terminus of the STATs [6,7] The phosphorylated and activated STATs form both homodimeric and heterodimeric complexes that translocate to the nucleus and bind speci c DNA sequences ... invasiveness and metastatic potential of pancreatic cancer cells [34] The JUND proto-oncogene may also influence the antiproliferative activity of IFNs JUND has been implicated in the activation of the...
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Tài liệu The Little Guide To Beating Procrastination, Perfectionism and Blocks: A Manual for Artists, Activists, Entrepreneurs, Academics and Other Ambitious Dreamers docx
... the heart of procrastination: fear of change, fear of failure and fear of success. Fear of Change A key difference between successful and unsuccessful people is that successful people initiate and control more of the changes in their lives. They decide where they ... stuck in their own ruts. Don’t underestimate this: rejection by, and alienation from, loved ones is a common, and often very hurtful, consequence of success. Success, in other words, is stressful, and sometimes greatly so. Children raised ... that you’ll win the lottery or that things will otherwise magically change, but hope, as they say, is not a strategy. The above compromises and sacrifices are, in fact, highly characteristic of those that ambitious people make to achieve their goals. All around you, ...
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Nitrosamine and related food intake and gastric and oesophageal cancer risk: A systematic review of the epidemiological evidence ppt
... Agency for Research on Cancer (IARC)[7] One previous comprehensive review on nutrition and cancer [8] concluded that there is convincing evidence that the consumption of the Chinese salted-dry fish ... NOC and also a source of other carcinogenic compounds, www.wjgnet.com 4300 ISSN 1007-9327 CN 14-1219/ R World J Gastroenterol such as heterocyclic amines (HA) and polycyclic aromatic hydrocarbons ... food intake, and risk of gastric cancer: epidemiologic evidence Cancer Sci 2005; 96: 1-6 Knekt P, Jarvinen R, Dich J, Hakulinen T Risk of colorectal and other gastro-intestinal cancers after exposure...
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What is known about the effectiveness of economic instruments to reduce consumption of foods high in saturated fats and other energy-dense foods for preventing and treating obesity? docx
... both tobacco and alcohol control, evidence suggests that the most effective approaches comprise multiple concurrent interventions, including price increases and other market restrictions and measures ... of Europe The other study was conducted in the United States, which has higher prevalence and risks of obesity than Europe, and a different socioeconomic profile and market factors Furthermore, ... conjunction with other programmes, such as correspondence, behaviour therapy and food provision, making it difficult to attribute any weight changes to the financial incentives Other incentives...
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Báo cáo " Thailand’s inadequate response to the 2008 Economic Crisis: Implications for Vietnam and other countries entering the East Asian economic model " pptx
... describe and analyse the stimulus package and other measures taken by the Thai government as a means of combating the economic crisis and then provides a critique of that response This is conducted ... decreasing relevance This process is accelerated or intensified by the onset of an economic crisis such as that which began in 2008 Under conditions of competition, some firms will fail and others ... which has proved to be brutal, corrupt and incompetent This has been revealed starkly by the response to the ongoing economic crisis, which has been characterised by lack of focus, short-termism,...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose