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![Tài liệu Báo cáo khoa học: Specific targeting of a DNA-alkylating reagent to mitochondria Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide doc](https://media.store123doc.com/images/document/14/br/vp/small_vpv1392870032.jpg)
Tài liệu Báo cáo khoa học: Specific targeting of a DNA-alkylating reagent to mitochondria Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide doc
... One approach to increase the duration of PNA binding to DNA is to conjugate it to a DNAalkylating reagent so that the PNA becomes covalently bound to its target sequence To this a DNA alkylating ... that mitoDC81 alkylates mtDNA in mitochondria or cells The reasons for the lack of alkylation of mtDNA within mitochondria by mitoDC-81 are unclear The local concentrations of mitoDC-81 and DNA, ... DNA ladder by mitoDC-81 (Fig 3B, lane 1) Analysis of the gel prior to electrotransfer showed that the extent of alkylation was proportional to the amount of DNA present and was independent of the...
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Báo cáo Y học: Incorporation of 3-nitrotyrosine into the C-terminus of a-tubulin is reversible and not detrimental to dividing cells potx
... significantly to the disappearance of nitrotyrosinated tubulin, the tyrosination/detyrosination at the C-terminus of a- tubulin is the main operating mechanism Furthermore, when cells maximally nitrotyrosinated ... indicates clearly that the two compounds are incorporated into tubulin at the same site Another biochemical characteristic of tubulin is its ability to act as substrate of the detyrosinating ... incubation was the same in both cases (data not shown), indicating that replacement of tyrosine by 3-nitrotyrosine at the C-terminus of a- tubulin is not relevant to the association of carboxypeptidase...
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Báo cáo khoa học: Proteome analysis of a rat liver nuclear insoluble protein fraction and localization of a novel protein, ISP36, to compartments in the interchromatin space pptx
... human cells J Cell Sci 108, 635– 644 10 Jagatheesan G, Thanumalayan S, Muralikrishna B, Rangaraj N, Karande AA & Parnaik VK (1999) Colocalization of intranuclear lamin foci with RNA splicing factors ... and characterization of a novel zinc finger protein that associates with nuclear matrix DNA Cell Biol 17, 849 –858 Lee JY, Nakane Y, Koshikawa N, Nakayama K, Hayashi M & Takenaga K (2000) Characterization ... with Coomassie Brilliant Blue A4 A6 are the same as A1 A3 except that the samples were blotted onto a nitrocellulose sheet, incubated with anti-His sera and then alkaline phosphatase-conjugated secondary...
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– THE GRE QUANTITATIVE SECTION – The area of a sector is found in a similar way to finding the pptx
... e e e e e e e e e e 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 a a a a a a a a a a a a a a a a a a a a a a a a a a a b b b b b b b b b b b b b b b b b b b ... area of a circle, use the formula A = r2 r ■ To find the area of a parallelogram, use the formula A = bh h b ■ To find the area of a rectangle, use the formula A = lw w l ■ To find the area of a ... find the volume of a cylinder, use the formula V = r2h h r S URFACE A REA The surface area of an object measures the combined area of each of its faces The total surface area of a rectangular...
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A study on some major factors affecting English learning of grade 6 ethnic minority students of a mountainous secondary school to help them learn better
... in addition to their native language The term “second language” is used to describe the acquisition of any language after the acquisition of the mother tongue There is also research into the ... likely to lead to dissatisfaction and alienation and not facilitate personal, social and academic growth; the best result are likely to occur when there is a combination of warmth and accomplishments ... instrumental motivation, the purpose of language acquisition is more utilitarian It is often characteristic of language learning acquisition, where little or no social integration of the learner into a...
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báo cáo sinh học:" Development of a quality assurance handbook to improve educational courses in Africa" docx
... child mortality, improving maternal health and combating HIV, malaria and other diseases The attainment of these goals has been hampered by the lack of skilled and well-informed health care workers ... handbook and this paper, drafting the handbook and this paper, and have approved the final version of the paper Acknowledgements We thank David Baume and Ian Willis for their helpful inputs to ... standards These are summarized below Quality assurance of recruitment and admissions Aim To ensure that courses are accessible to the entire community and that the admissions procedures are fair,...
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báo cáo sinh học:" Improving pneumonia case-management in Benin: a randomized trial of a multi-faceted intervention to support health worker adherence to Integrated Management of Childhood Illness guidelines" doc
... clinical data into a diagnosis Another example was that incomplete documentation, which could confuse pharmacists and caretakers, was relatively common The analysis also revealed that some potentially ... we used a simple graphical pathway analysis In quality improvement methodologies, this is conceptually similar to a "rootcause" analysis [ 24] We began with the ideal case-management pathway IMCI ... Definitions of the indicators of pneumonia case-management quality Definitions of the indicators of pneumonia case-management quality To examine specific causes of common errors in the casemanagement...
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báo cáo hóa học: " Psychometric properties of a single-item scale to assess sleep quality among individuals with fibromyalgia" potx
... and the average duration of FM was years In study 1077, the mean age of patients was 50.1 years and the average dura- Table 1: Baseline patient characteristics and sleep scores Characteristics ... possible pain") Further, study patients had to have a score of at least 40 mm on the 100 mm visual analogue scale (VAS) of the Short-Form McGill Pain Questionnaire [ 14] at the screening and baseline ... clinical trials During the baseline phase, study patients had to have an average daily diary pain score of at least (within the last days) on a numeric rating scale ranging from ("no pain") to 10...
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báo cáo hóa học: " Development of a self-reporting tool to obtain a " docx
... into Spanish Arthritis Rheum 1995, 38: 142 9- 144 6 26 Garc a- Campayo J, Pascual A, Alda M, Marzo J, Magallón R, Fortes S: The Spanish version of the fibrofatigue scales: validation of a questionnaire ... Questionnaires analysis FIQ An exploratory factor analysis with a Kaiser-MeyerOlkin (KMO) index of 0.83, yielding two factors that explained 57% of the variance The first explains 44 % of the variance ... conceived the study MAV designed the study and perform the statistical analysis These authors revised the data obtained and draft the manuscript MAV coordinated the analysis, results and discussion All...
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Báo cáo hóa học: " Development of a 3D immersive videogame to improve arm-postural coordination in patients with TBI" potx
... was calculated as the ratio of the actual arm trajectory length to the shortest path to the target A ratio of indicates no arm deviation from the shortest path, while a ratio of indicates that ... thigh and shank, was analysed as a single segment since the angular displacement at the knee joint was minimal for this task The vector of temporal variation of the segmental angles i around their ... ultimate goal is to collect as many characters as possible and get the final reward, an animated Mermaid, who is sitting on the coral reef and waving her tail All these actions are added to slightly...
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Báo cáo hóa học: " Use of a commercial enzyme immunoassay to monitor dengue virus replication in cultured cells" doc
... S, Vaughn DW, Kalayanarooj S, Nisalak A, Norman JE, Ennis FA, Rothman AR: Analysis of plasma viral RNA levels during acute dengue virus infection using quantitative competitor reverse transcription-polymerase ... 13:1185-1189 Kumarasamy V, Chua SK, Hassan Z, Huahab AHA, Chem JK, Mohamad M, Chua KB: Evaluating the sensitivity of a commercial dengue NS1-antigen capture ELISA for early diagnosis for acute dengue ... determined at 45 0 nm using an automatic ELISA plate reader (Multiskan EX, Labsystems) Negative, positive and cut-off control reagents provided with the kit were run each time for validation of the assay...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose