4 the limits of human power
Báo cáo khoa học: Effect of heliquinomycin on the activity of human minichromosome maintenance 4/6/7 helicase pdf
... 0 .43 1 .4 4.3 (μM) HQ 14 43 + Werner 1 .4 0 .43 4. 3 14 43 (μM) HQ 17-mer/M13 B 17-mer 120 100 % 80 60 40 20 33 84 0 .43 4. 3 1 .4 (μM) HQ 14 43 Heliquinomycin at an IC50 value of 7– 14 lm inhibits the ... interaction of + MCM4/6/7 A + Tag 1 .4 14 1 .4 14 0 .43 4. 3 43 0 .43 4. 3 43 (μM) HQ Pi ATP B 120 100 Tag % 80 60 40 20 MCM 0 .43 1 .4 4.3 (μM) HQ 14 43 Fig (A) Effect of increasing concentrations of heliquinomycin ... in the absence of single-stranded DNA (Fig 5) Heliquinomycin inhibited the ATPase + MCM4/6/7 + Tag 1 .4 14 1 .4 14 0 0 .43 4. 3 43 0 .43 4. 3 43 (μM) HQ Pi examined the effect of heliquinomycin on the...
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Báo cáo y học: "Antigenic presentation of heterologous epitopes engineered into the outer surface-exposed helix 4 loop region of human papillomavirus L1 capsomeres" potx
... abolished all but the first residue of h4 (aa 41 3 43 0; termed B-1) and another that deleted h4 and additional surrounding residues, including the prolines flanking both sides of h4 (aa 40 4 43 6; C-1, ... such that the h4 domain is shown protruding out of the plane of the diagram Shown below the schematic is the aa sequence of L1 h4 and its surrounding residues 40 1 – 43 9; those comprising h4 are highlighted ... http://www.virologyj.com/content/6/1/81 Figure The h4 domain of the HPV 16L1 monomer The h4 domain of the HPV 16L1 monomer Shown is a ribbon diagram of the HPV 16L1 monomer that is visualized using the Cn3D program (NIH)...
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Báo cáo khoa học: "Antigenic presentation of heterologous epitopes engineered into the outer surface-exposed helix 4 loop region of human papillomavirus L1 capsomeres" docx
... abolished all but the first residue of h4 (aa 41 3 43 0; termed B-1) and another that deleted h4 and additional surrounding residues, including the prolines flanking both sides of h4 (aa 40 4 43 6; C-1, ... such that the h4 domain is shown protruding out of the plane of the diagram Shown below the schematic is the aa sequence of L1 h4 and its surrounding residues 40 1 – 43 9; those comprising h4 are highlighted ... http://www.virologyj.com/content/6/1/81 Figure The h4 domain of the HPV 16L1 monomer The h4 domain of the HPV 16L1 monomer Shown is a ribbon diagram of the HPV 16L1 monomer that is visualized using the Cn3D program (NIH)...
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THE INFLUENCE OF HUMAN ACTIVIES ON THE ENVIRONMENT
... fuels in cars and power stations produces carbon dioxide, sulphur dioxide and other greenhouse gases • carbon dioxide traps heat in the atmosphere and causes the temperature of the earth to rise ... problems Burning the timber increases the level of carbon dioxide in the air Less trees means less carbon dioxide absorbed for photosynthesis Soil is eroded as it is exposed to the wind and rain ... the earth to rise • This leads to disruption of the weather patterns eg drought, floods • Some weeds may thrive on the extra carbon dioxide while other plants are killed Sulphur dioxide will dissolve...
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Tài liệu The Influence of Human Activity on the Environment ppt
... fuels in cars and power stations produces carbon dioxide, sulphur dioxide and other greenhouse gases • carbon dioxide traps heat in the atmosphere and causes the temperature of the earth to rise ... problems Burning the timber increases the level of carbon dioxide in the air Less trees means less carbon dioxide absorbed for photosynthesis Soil is eroded as it is exposed to the wind and rain ... the earth to rise • This leads to disruption of the weather patterns eg drought, floods • Some weeds may thrive on the extra carbon dioxide while other plants are killed Sulphur dioxide will dissolve...
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Tài liệu Báo cáo khoa học: Insights into the interaction of human arginase II with substrate and manganese ions by site-directed mutagenesis and kinetic studies Alteration of substrate specificity by replacement of Asn149 with Asp docx
... consequence of the mutagenic replacements Effects of the His120Asn and His 145 Asn mutations on the affinity of metal binding to arginase II To further examine the effects of the His120fiAsn and His 145 fiAsn ... sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72, 248 –2 54 FEBS Journal 272 (2005) 45 40 45 48 ª 2005 FEBS ... respectively [9, 24] However, the volume of the active site cleft was found to be larger for arginase II Moreover, the D232 (Od1)-Mn2+B FEBS Journal 272 (2005) 45 40 45 48 ª 2005 FEBS Interaction of arginase...
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THE REPRODUCTION OF LABOR-POWER IN THE GLOBAL ECONOMY, MARXIST THEORY AND THE UNFINISHED FEMINIST REVOLUTION ppt
... immediate was the refusal of the slogans of the Marxist left, such as the ideas of the "general strike" or "refusal of work," both of which were never inclusive of house-workers Over time, the realization ... expressed the interests of a limited sector of the world proletariat, that of white, adult, make workers, largely drawing their power from the fact that they work in the leading sectors of capital ... where the capitalist organization of work is viewed as the highest model of historical rationality, held up for every other form of production, including the reproduction of the work-force In other...
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Báo cáo khoa học: Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down-regulating fibrinolysis doc
... F201T, I204Y, I205E, I204Y ⁄ I205E, L214N, F 244 T, L281S, L335S, L376Q, T 347 I) Based on the alignment of CPU sequence to the structure of carboxypeptidase FEBS Journal 273 (2006) 778–792 ª 2006 The ... connected to an increased thermostability of the protein itself, we monitored the thermal unfolding of WT and YQ proCPU-CHis Compared with the WT, the midpoint temperature (Tm) of the protein-unfolding ... aggregation of the protein This is further confirmed by the existence of a natural variant of CPU, where T 347 is subsituted by an I Although accentuating the hydrophobic 786 character of the protein...
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Báo cáo khoa học: The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides pot
... center of the input target RNA The asterisk indicates the input target RNA; the arrow indicates the digested product bands The amount of digested product obtained is indicated at the bottom of the ... analyze the effects of ODNs delivered by electroporation The data of the 15PC3 cells are compatible with the hypothesis that RNase H2 can play a role in the in vivo response of cells They are the ... MiaPacaII 40 0 nM 600 nM 800 nM HEK293 40 0 nM 600 nM 800 nM 15PC3 40 0 nM 600 nM 800 nM Liposomal Electroporation 4. 4 0.0 6 .4 0.8 10 .4 0.9 7.8 2.0 ND 24. 2 1.0 4. 2 0.6 6.8 0.9 8.7 0 .4 ND...
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Bacteria are often maligned as the causes of human and animal disease (like this one, Leptospira, which causes serious disease in livestock)
... as the Democratic Republic of Congo In these two instances the mortality rate was between 50 –90% Following those epidemics, Ebola hit Africa in many other instances the worst yet being in the ... the September 11 bombings in the United States, the locality of this virus has become less isolated as the threat of bioterrorism looms large The Ebola virus is now on the “A” list for hopeful vaccination ... based on ideas of right and wrong when dealing with the geographical distribution of animals and plants This concept of can be used to explain the world’s shockingly small response to the Ebola...
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BELMONT REPORT: ETHICAL PRINCIPLES AND GUIDELINES FOR THE PROTECTION OF HUMAN SUBJECTS OF RESEARCH ppt
... 19 74, the National Research Act (Public Law 93 348 ) was signed into law, thereby creating the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research One of ... to be among the beneficiaries of subsequent applications of the research C Applications Applications of the general principles to the conduct of research leads to consideration of the following ... conflicting judgments Thus, there should first be a determination of the validity of the presuppositions of the research; then the nature, probability and magnitude of risk should be distinguished,...
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Báo cáo khoa học: Cell death-inducing DFF45-like effector, a lipid droplet-associated protein, might be involved in the differentiation of human adipocytes pdf
... confluence After 14 days of induction, the majority of the cells displayed a phenotype of mature adipocytes (Fig 4A) The neutral 41 76 lipids accumulated in the cytoplasm, and a large number of lipid droplets ... between the 14th and 16th weeks of gestation in humans, and that the second trimester of gestation is the critical period in adipogenesis After the 23rd week of gestation, although the number of fat ... during the differentiation of pre-adipocytes (Fig 4C), which was consistent with the change of protein levels These data suggest that the expression of CIDEC might be attributable to the differentiation...
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Báo cáo khoa học: "THE LIMITS OF UNIFICATION" ppt
... In (44 ), the constitutent level at which neutralization is attempted is that of the phrase (N-P), whereas in (43 ) and (45 ) it is at the level of the pre-tenninal (N) Zaenen and Karttunen (19 84, ... following the past auxiliary and a weak Cclitic") object pronoun which is the common object of the conjoined participles, under the requirement that the verbs of the conjuncts assign the pronoun the ... where the dominating constituent is a projection of the dominated, in the sense of the X-Bar theory of phrase structure (Choresky (1970), lackendoff (1977)) For example, a noun phrase has the same...
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Báo cáo khoa học: Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates potx
... Hellman L (2009) The extended substrate specificity of the human mast cell chymase reveals a serine protease with Cathepsin G versus chymase specificity 35 36 37 38 39 40 41 42 43 44 45 46 47 well-defined ... S1¢ pocket on the top of the Cys42-Cys58 loop is bordered by His57 to the west and the aliphatic part of the Lys40 side-chain to the east [2] (Fig 1) As a result, the P1¢ specificity of chymase could ... result of the presence of negatively-charged residues at P2 and P2¢ that are not accommodated within the b2-tryptase active site because of the presence of Asp 147 and Asp 143 within the S2 and the...
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Intellectual Property and the Limits of Antitrust potx
... services on the basis of the transactions of commercial operators, has the effect of hindering the maintenance of the degree of competition still existing in the market or the growth of that competition .47 ... between the monopolization offense and the abuse of dominance, the state action doctrine and the immunity for government petitioning, all of which are crucial to the understanding of the limits of ... Corp., 44 2 U.S 330, 343 (1979) (the Congress designed the Sherman Act as a consumer welfare prescription) and the Article 82 Discussion Paper, 4 (The objective of Article 82 is the protection of...
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Báo cáo khóa học: The role of N-linked glycosylation in the protection of human and bovine lactoferrin against tryptic proteolysis pdf
... scale production of recombinant human lactoferrin in the milk of transgenic cows Nat Biotechnol 20, 48 4 48 7 23 Brines, R.D & Brock, J.H (1983) The effect of trypsin and chymotrypsin on the in vitro ... (1990) Properties of the iron-binding site of the N-terminal lobe of human and bovine lactotransferrins Importance of the glycan moiety and of the non–covalent interactions between the N- and C-terminal ... (Fig 4) This result indicates that the absence of glycosylation in rhLFGln138 /47 9, which has the naturally occurring Gly4 04, does not lead to increased tryptic susceptibility of the rhLFGln138 /47 9...
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