3 play a role in tumor angiogenesis
Báo cáo Y học: Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation? ppt
... 535 7 an anabolic stimulus, may largely induce increased translation across the board of mRNAs that are already actively being translated How could increased phosphorylation of eIF4E actually inhibit ... eukaryotic mRNAs that are translated at reduced cap binding complex eIF4F concentrations using a cDNA microarray Proc Natl Acad Sci USA 96, 131 18– 131 23 74 Mikulits, W., Pradet-Balade, B., Habermann, B., ... internal fragment by caspase -3- mediated cleavage Cell Death Differ 7, 628– 636 23 Tee, A. R & Proud, C.G (2000) DNA damage causes inactivation of translational regulators linked to mTOR signalling...
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báo cáo khoa học: " Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their role in tumor angiogenesis" pps
... natural angiogenic inhibitors [3] Maspin, a serine protease inhibitor in the serpin superfamily, functions as a tumor suppressor by inhibiting tumor cell motility, invasion, metastasis and angiogenesis ... expression in ovarian borderline mucinous cystadenoma; C: Ang-2 expression in left ovarian serous papillary cystadenocarcinoma; D: Ang-2 expression in ovarian borderline mucinous cystadenoma; E: Maspin ... Ets-1, Ang-2 and maspin and the clinical manifestation of ovarian cancer Statistical analysis revealed that Ets-1 expression had no obvious correlation with age, pathological types, grade, stage and...
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báo cáo khoa học: " Do mitochondria play a role in remodelling lace plant leaves during programmed cell death?" pps
... by asterisk) and showed absolutely no staining (Figure 3J and 3K) These mitochondria appeared to have dramatically degraded cristae and nearly indistinguishable membranes via TEM imaging and also ... leading to cell death in Arabidopsis thaliana Annals of Bot 2005, 96 :33 7 -34 2 Vacca RA, de Pinto MC, Valenti D, Passarella S, Marra E, De Gara L: Production of reactive oxygen species, alteration ... significant decrease in perforation formation within the lace plant via CsA application indirectly indicates that the PTP pathway may play a role in cellular death within this system Although the involvement...
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báo cáo hóa học:" Spontaneous regression of curve in immature idiopathic scoliosis - does spinal column play a role to balance? An observation with literature review" pot
... contributed in acquisition of data, revising the manuscript critically and given the final approval, JYH has contributed in acquisition of data and analysis and interpretation of data; and KPV and NM have ... differential pressure loading on the growth plate [31 ] Eular’s Law of viscoelastic buckling of a spine in the coronal and transverse planes Page of leading to a lateral bend and axial rotation/torsional ... changed training conditions [24] During a muscle training program lasting several weeks, a distinct increase in activity occurs during the first weeks; the activity then drops to the initial value...
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Báo cáo y học: "Migration events play significant role in genetic differentiation: A microsatellite-based study on Sikkim settlers" ppt
... populations of Sikkim along with comparative data from other populations Locus Nepali Bhutia Lepcha Naga Kuki Hmar Garo Chinese Caucasian Brahmin Brahmin Brahmin (Karnataka) (Orissa) (Bihar) D3S 135 8 ... population and exhibit a high level of diversity In India, mongoloids contribute approximately 3% of the total population, mainly inhabiting the hills and adjoining plains of Northeast and Central ... that migratory events have played a significant role in the differentiation of mongoloids of India Background The origin, dispersal and antiquity of Homo sapiens in the Asian peninsula have attained...
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Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf
... resulting double-stranded DNA was cloned in frame with VP16 MT1/MYC has a MYC tag between P312 and T3 13 in the hinge domain of MT1-MMP LLY570-573AAA MT1/MYC and G 2A GRASP55F mutants were generated ... from F Barr and colleagues [35 ] GRASP55F in pCDNA3.1 Zeo+ contained a C-terminal FLAG tag Full-length GRASP55, GRASP55 PDZ1 (amino acids 1–107), GRASP55 PDZ2 (amino acids 84–172) and GRASP55 region ... multimerization can involve either of the PDZ domains, as for example in glutamate receptor interacting protein (GRIP1) [55] Role of GRASP55 in MT1-MMP activation or inactivation no afterpotential D (INAD)...
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Tài liệu Báo cáo khoa học: Differentiation stage-dependent preferred uptake of basolateral (systemic) glutamine into Caco-2 cells results in its accumulation in proteins with a role in cell–cell interaction pptx
... (2004) A combination of protein profiling and isotopomer analysis using FEBS Journal 272 (2005) 33 50 33 64 ª 2005 FEBS Glutamine incorporation in Caco-2 proteins 30 31 32 33 34 35 36 37 38 39 40 ... glutamine plays an important role in enterocyte homeostasis and function [34 ], also in intestinal injury [35 ], few data are available on the uptake mechanisms of glutamine by the basolateral 33 54 m⁄z ... the alpha-actinin protein family, alpha-actinin 1, has been shown to be involved in cadherin-mediated cell–cell adhesion via alpha-catenins in adherens junctions of epithelial cells [ 53] The fact...
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Peptidylarginine deiminase (PAD) is a mouse cortical granule protein that plays a role in preimplantation embryonic development docx
... http://www.rbej.com/content /3/ 1/42 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 Nakashima K, Hagiwara T, Yamada M: Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes ... abundant peptidylarginine deiminase) Mouse cortical granules contain PAD To ascertain if mouse cortical granules contain PAD, antibodies made against mouse ePAD and human recombinant PAD V (anti-PAD ... V1.0) [35 -37 ] were used to determine that a putative signal peptide and a cleavage site exist in ePAD and AAH 537 24 (an egg and embryo abundant peptidylarginine deiminase), indicating they are likely...
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Báo cáo khoa học: No evidence for a role in signal-transduction of Na+/K+-ATPase interaction with putative endogenous ouabain potx
... Natl Acad Sci USA 88, 6259–62 63 Hansen, O (1989) Characterization of fatty acid interaction with ouabain and vanadate binding to (Na++K+) -activated ATPase Biochim Biophys Acta 986, 130 – 134 Hansen, ... larger changes in intracellular Na+ and Ca2+ may thus be the result of a ouabain interaction with subpopulations of Na+/K+ATPase [27] An overall increase in intracellular Na+ was seen in the experiments ... another group in collaboration with Hamlyn [21] by means of two independent assays, a radioimmunoassay using an anti-ouabain Ig and an enzymatic assay using ouabain-sensitive Na+/K+ATPase from dog...
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Research Directions in Tumor Angiogenesis Edited by Jianyuan Chai pptx
... Ohsaki, Veronika Sysoeva, Mathias Francois, Jeroen Overman, Mani Valarmathi, Qigui Li, Mark Hickman, Peter Weina, Jianyuan Chai, Ramani Ramchandran, Jill Gershan, Andrew Chan, Magdalena Chrzanowska-Wodnicka, ... Cells in Tumor Angiogenesis — Tumor- Associated Pericytes 73 Yoshinori Minami, Takaaki Sasaki, Jun-ichi Kawabe and Yoshinobu Ohsaki Chapter Endothelial and Accessory Cell Interactions in Neuroblastoma ... artemisinin, an extract from the plant sagewort Artemisinin is the first line treatment recommended by WHO for malaria However, an increasing amount of data indicates an anti-cancer effect, particularly...
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Báo cáo hóa học: " Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment" pptx
... (DEN)inducedHCC) in rats Gallic acid treatment significantly attenuated some alterations (i.e increased levels of aspartate transaminase, alanine transaminase, alkaline phosphatase, acid phosphatase, lactate ... relevant NS3- 4a has also been demonstrated to inactivate the cellular protein toll-interleukin-1 receptor domain-containing adaptor inducing IFN (TRIF) TRIF is an adaptor protein that is a critical ... (TIRdomain-containing adapter-inducing interferon-b) joining the RIG-I/MDA5 pathway In the other pathway, TLR7 senses single-strand HCV RNA and via the MyD88 adaptor protein activates IRAK4/IRAK1 These kinases...
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báo cáo hóa học:" Triple-Nucleoside Analog Antiretroviral Therapy: Is There Still a Role in Clinical Practice? A Review" docx
... Montaner J, et al.: Abacavir-lamivudinezidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial JAMA 2001, 285:1155-11 63 Abstract ... ITT analysis) These data again show that a tNRTI regimen that contains a thymidine analog with 3TC and ABC has virologic efficacy comparable to that of a PIbased regimen, but inferior to that ... W: Early non-response to tenofovir DF (TDF) + abacavir (ABC) and lamivudine (3TC) in a randomized trial compared to efavirenz (EFV) + ABC and 3TC: ESS30009 unplanned interim analysis Program and...
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Báo cáo y học: "ignal 3 and its role in autoimmunity" pot
... Horai R, Saijo S, Tanioka H, Nakae S, Sudo K, Okahara A, Ikuse T, Asano M, Iwakura Y: Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin receptor antagonist-deficient ... Lucian L, To W, Kwan S, Churakova T, Zurawski S, Wiekowski M, Lira SA, Gorman D, Kastelein DA, Sedgwick JD: Interleukin- 23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation ... highlights the critical role of IL-1ra in the constitutive maintenance of peripheral tolerance, and in counterbalancing the proinflammatory effects of IL-1 and IL-17 Conclusions Although apparently simple,...
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Báo cáo y học: "Do the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases" pdf
... states beyond atherogenesis Sparrow and colleagues demonstrated that simvastatin had a comparable antiinflammatory effect to that of indomethacin in the carrageenan-induced foot pad oedema inflammatory ... reductions in inflammatory cell infiltrate and eosinophilia in bronchoalveolar lavage fluid were observed with both oral and intraperitoneal administration of simvastatin [36 ] Continuing studies are addressing ... studies are emerging In a murine model of allergic asthma, we recently showed potential benefits of statin therapy on inflammatory airway disease After priming and intra-nasal ovalbumin challenge,...
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Báo cáo y học: "Endogenous and exogenous stem cells: a role in lung repair and use in airway tissue engineering and transplantation" pdf
... 53 Komura M, Komura H, Kanamori Y, Tanaka Y, Suzuki K, Sugiyama M, Nakahara S, Kawashima H, Hatanaka A, Hoshi K, Ikada Y, Tabata Y, Iwanaka T: An animal model study for tissue-engineered trachea ... Thorac Cardiovasc Surg 2010, 139 : 437 -4 43 30 Suzuki T, Kobayashi K, Tada Y, Suzuki Y, Wada I, Nakamura T, Omori K: Regeneration of the trachea using a bioengineered scaffold with Page of 31 32 33 ... reprogramming Nature 2009, 460:1 136 -1 139 Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, Nakagawa M, Okita K, Yamanaka S: Suppression of induced pluripotent stem cell generation by the p 53- p21...
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Báo cáo khoa học: "Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions" ppt
... of the coated vesicle adaptor protein complex (AP): γ-adaptin, a marker for AP-1 [41]; δ-adaptin, a marker for AP -3 [42] Both AP-1 and AP -3 localizes to TGN and endosomes, with AP -3 localizes more ... http://www.virologyj.com/content/6/1/168 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 Koshizuka T, Goshima F, Takakuwa H, Nozawa N, Daikoku T, Koiwai O, Nishiyama Y: Identification and characterization of ... Ulbrich A, Matsuda A, Reddy VA, Orth A, Chanda SK, Batalov S, Joazeiro CA: Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates...
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báo cáo khoa học: " Co-expression and promoter content analyses assign a role in biotic and abiotic stress responses to plant natriuretic peptides" pptx
... physiological role of AtPNP -A in A thaliana a T-DNA insertion mutant, that is available from SALK, could be used Phenotyping this mutant in response to SA-inducing abiotic and biotic stresses as well as ... Bray EA: Role of abscisic acid (ABA) and Arabidopsis thaliana ABA-insensitive loci in low water potentialinduced ABA and proline accumulation J Exp Bot 2006, 57:201-212 Denby K, Gehring C: Engineering ... antifreeze protein in Arabidopsis thaliana results in a decrease in plant freezing temperature Plant Mol Biol 2002, 50 :33 3 -34 4 Hara K, Yagi M, Kusano T, Sano H: Rapid systemic accumulation of transcripts...
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Báo cáo y học: "bench-to-bedside review: Endothelial cell dysfunction in severe sepsis: a role in organ dysfunction" pdf
... trial of antithrombin III concentrates in septic shock with disseminated intravascular coagulation Chest 19 93, 104:882-888 34 Baudo F, Caimi TM, de Cataldo F, Ravizza A, Arlati S, Casella G, Carugo ... Szymanski LM: The suprapharmacologic dosing of antithrombin concentrate for Staphylococcus aureus-induced disseminated intravascular coagulation in guinea pigs: substantial reduction in mortality ... [17,60,61], have demonstrated attenuated acetylcholine-induced relaxation in vascular rings isolated from large arteries Apart from anatomical injuries, such abnormalities observed in these vessels may...
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Báo cáo khoa học: "Do statins have a role in preventing or treating sepsis" pptx
... statins may also ameliorate sepsis-induced coagulopathy [5,8,9] Another novel pathway may play an important role in attenuating sepsis-induced endothelial dysfunction Heme oxygenase (HO)-1 is an ... comorbidities and dissipated when the medication was discontinued There is growing interest among clinicians in the role that statins may play in preventing and treating serious infections If such an effect ... or placebo was initiated hours after sepsis induction, when profound hemodynamic alterations were already evident, survival time was again significantly extended in treated Available online http://ccforum.com/content/10/1/113...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25