2background for intramyocardial stem cell transplantation in cardiac surgery

Dynamic mechanical stimulation for mesenchymal stem cell chondrogenesis in an elastomeric scaffold

Ngày tải lên : 09/09/2015, 08:12

... elaboration on cell sources, in particular that of stem cells, and the biomaterials, for cartilage tissue engineering will be addressed 2.3.1 Stem cell based Approaches for Cartilage Tissue Engineering ... TGF-β/Activin/Nodal Signaling by SB431542…… ……….74 5.2.8 Effect of TGF-β/Activin/Nodal Signaling Inhibition on Integrin β1/FAK Signaling and BMP/GDP Branch Signaling………………………… … 75 5.2.9 Inhibition of Integrin ... markers with integrin β1 inhibition in free swelling conditions Fig 32 The distribution and quantification of pSMAD2/3 and pSMAD1/5/8 at week in free swelling samples with integrin β1 inhibition...

142
233
0

Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" doc

Ngày tải lên : 12/08/2014, 04:21

... Bilateral interstitial infiltrates clinical studies have to be performed to examine the frequency of clinically relevant HHV-6 infections in these patient cohorts Consent statement Written informed ... patients after autologous stem cell transplantation Nevertheless, in patients with severe complications of infections after autologous stem cell transplantation or intensive chemotherapeutic ... hematopoietic stem cell transplantation Clin Infect Dis 2005, 40:932-940 Bissinger AL, Einsele H, Hamprecht K, Schumacher U, Kandolf R, Loeffler J, Aepinus C, Bock T, Jahn G, Hebart H: Infectious...

3
366
0

Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" ppsx

Ngày tải lên : 12/08/2014, 04:22

... Bilateral interstitial infiltrates clinical studies have to be performed to examine the frequency of clinically relevant HHV-6 infections in these patient cohorts Consent statement Written informed ... patients after autologous stem cell transplantation Nevertheless, in patients with severe complications of infections after autologous stem cell transplantation or intensive chemotherapeutic ... hematopoietic stem cell transplantation Clin Infect Dis 2005, 40:932-940 Bissinger AL, Einsele H, Hamprecht K, Schumacher U, Kandolf R, Loeffler J, Aepinus C, Bock T, Jahn G, Hebart H: Infectious...

3
303
2

Tài liệu Review of Chronic Graft- Versus-Host Disease in Children After Allogeneic Stem Cell Transplantation: Nursing Perspective pptx

Ngày tải lên : 12/02/2014, 19:20

... mends a system for scoring chronic GVHD manifestations in organs and sites, including the skin, mouth, eyes, gastro intestinal tract, liver, lungs, joints and fascia, genital tract, and performance, ... GVHD is initiated, T-cells produce additional proinflammatory cytokines, including tumor necrosis fac tor (TNF)-α, interferon (IFN)-γ, and interleukin (IL)-2, which in turn attract more T-cells ... (Th2) cells can initiate a response against autoantigens leading to B -cell hyperre activity and production of autoantibodies, causing targetorgan damage, including skin, mucosa, eyes, joints,...

10
686
0

Tài liệu INNOVATIONS IN STEM CELL TRANSPLANTATION doc

Ngày tải lên : 18/02/2014, 04:20

... blood cell or a brain cell During this last decade, the number of published articles or books investigating the role of stem cells in cell transplantation or regenerative medicine increased remarkably ... the recent developments in the field of basic and clinical aspects of stem cells and cell transplantation Although we are close to finding pathways for stem cell therapies in many medical conditions, ... transplanted stem cells in the host In conclusion, Cell Transplantation is bridging cell transplantation research in a multitude of disease models as methods and technology continue to be refined The...

378
338
1

Tài liệu New Advances in Stem Cell Transplantation Edited by Taner Demirer ppt

Ngày tải lên : 20/02/2014, 08:20

... factors into somatic cells By using these viral delivery systems, 12 New Advances in Stem Cell Transplantation Fig Methods for producing induced pluripotent stem cells (iPSCs) by non-integrating ... factor 1/PD2 maintains self-renewal by its interaction with Oct3/4 in mouse embryonic stem cells Stem Cells 27, 30013011 22 New Advances in Stem Cell Transplantation Rai, K., Huggins, I.J., James, ... medicine or reparative medicine During this last decade, the number of published articles or books investigating the role of stem cells in cell transplantation or regenerative medicine increased...

594
673
0

Báo cáo y học: "Hematopoietic stem cell transplantation for systemic lupus erythematosus" ppsx

Ngày tải lên : 09/08/2014, 01:23

... marrow stem cell transplantation for severe systemic lupus erythematosus of long duration Lupus 1997, 6:545-548 Burt RK, Traynor A, Ramsey-Goldman R: Hematopoietic stemcell transplantation for systemic ... versus the Hopkins’ treatment protocol incorporating high-dose cyclophosphamide without stem cell support Competing interests None declared References 10 11 12 13 14 Marmont AM, van Lint MT, Gualandi ... Therefore, circulating T cells in a healthy person normally possess a T -cell receptor repertoire selected to a self-epitope Immune cells may be viewed as a dynamic equilibrium that maintains steady...

3
306
0

Báo cáo y học: "Stem cell transplantation for rheumatic autoimmune diseases" potx

Ngày tải lên : 09/08/2014, 10:23

... reduced proteinuria, immune complex formation, and antinuclear antibodies (ANAs) While the aforementioned preclinical studies have been instrumental in demonstrating basic principles of HSCT in experimental ... Figure Resetting of the immunological clock following hematopoietic stem cell transplantation Hematopoietic stem cell transplantation (HSCT) is a complex multistep procedure involving mobilisation ... obtained from studies showing increases in T -cell receptor excision circles and CD31+ T cells and normalisation of new T -cell receptor repertoires [53,54] Allogeneic hematopoietic stem cell transplantation...

10
342
0

Báo cáo y học: "Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert’s syndrome" pptx

Ngày tải lên : 10/08/2014, 21:23

... the conditioning and within 100 days after transplantation, although indirect hyperbilirubinemia repeatedly happened during chemotherapy with daunorubicin, idarubicin, and cytarabine prior to ... days to +28) for GVHD prophylaxis; Caspofungin for prophylaxis of fungal infections] Tropisetron was used during the chemotherapy and conditioning (E) period of acute GVHD [alanine aminotransferase ... developed indirect hyperbilirubinemia during the course of their treatment No patients died from the liver dysfunction In our case, transaminase and bilirubin levels were almost normal during the...

3
366
0

Báo cáo y học: "Frequency analysis of TRBV subfamily sjTRECs to characterize T-cell reconstitution in acute leukemia patients after allogeneic hematopoietic stem cell transplantation" pot

Ngày tải lên : 10/08/2014, 21:23

... mM MgCl2 After an initial denaturation at 95°C for min, 45 cycles consisting of 95°C for 30 s and 67°C for were performed The amplification was performed on MJ Research DNA Engine Opticon PCR cycler ... and reaching a plateau months after HSCT, indicating ongoing thymic output Although fludarabine-based, non-myeloablative conditioning was performed in both studies, the regimen used in the Bahceci ... BioSciences, USA) Stainings were performed by incubating cells with the appropriate pool of antibodies for 30 at 4°C followed by a series of washes with phosphate-buffered saline solution supplemented...

8
345
0

báo cáo khoa học: "Current status of haploidentical stem cell transplantation for leukemia" pps

Ngày tải lên : 10/08/2014, 22:20

... donor hematopoietic stem cells by combining G-CSF mobilized peripheral blood with bone marrow stem cells, both depleted of T cells, following TBI-based conditioning regimens[16-18] In their early ... haploidentical T -cell- replete hematopoietic stem cell transplantation Hematologica 2007, 92:414-417 Bignon JD, Gagne K: KIR matching in Hematopoietic stem cell transplantation Curr Opin Immunol 2005, ... stem cell transplantation using unrelated donors Blood 2004, 103:2860-2862 Lowe EJ, Turner V, Handgretinger R, et al.: T -cell alloreactivity dominates natural killer cell alloreactivity in minimally...

9
379
0

Báo cáo y học: "Marked increase of procalcitonin after the administration of anti-thymocyte globulin in patients before hematopoietic stem cell transplantation does not indicate sepsis: a prospective study" pptx

Ngày tải lên : 13/08/2014, 16:20

... clinical conditions, including cardiac surgery [18] and heatstroke [19], with increased PCT of non-infectious causes were reported In healthy term neonates, a transient increase in PCT peaking ... Anti-thymocyte globulin (ATG) administered during conditioning before hematopoietic stem cell transplantation triggered a marked increase in both procalcitonin (PCT) and C-reactive protein (CRP) with a peak ... significant trends were observed for bilirubin and GGT In contrast, ALT increased only transiently on day There were no changes in urea, creatinine, or GFR during conditioning Progressive depletion...

7
262
0

báo cáo hóa học:" Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson''''s disease" doc

Ngày tải lên : 18/06/2014, 15:20

... brain injection on a stereotaxic frame (Myneurolab, USA) 6-OHDA (6 μg in μl) was dissolved in normal saline containing ascorbic acid (0.2 mg/ml), and injected into the right medial forebrain ... peroxidase-coupled avidin-biotin staining kit (ABC kit, Vector Laboratories, UK) were used For HE staining, the tissue sections were submerged into the hematoxylin solution (0.5% hematoxylin, 5% aluminium ammonium ... is found in the RPE cells in our study However, the depolarization-induced DA release is not detected in the cells, indicating that the DA release machinery as seen in most excitable cells is...

9
449
0

báo cáo hóa học:" MUC4 stabilizes HER2 expression and maintains the cancer stem cell population in ovarian cancer cells" ppt

Ngày tải lên : 20/06/2014, 07:20

... (Jackson Immunoresearch Labs, Inc., West Grove, PA, U.S.A.) containing 0.05% Tween-20 for at least 30 minutes For Phalloidin staining, cells were fixed with 3.6% formaldehyde-PBS solution and ... membrane-bound mucin MUC1 maintains a small population of stem/ progenitor cells in the breast cancer (MCF7) cell line [11] The fact that the vast majority of MCF7 stem cell enriched SP cells express ... overexpressed cells behave like cancer stem cells which are capable of maintaining the self-renewal property (Figure 5) Figure Colony formation in MUC4-trasfected cells SKOV3-Vector and SKOV3-MUC4 cells...

10
336
0

Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 1) ppt

Ngày tải lên : 07/07/2014, 01:20

... of Stem Cells for Tissue Repair Different types of stem cells include embryonic stem (ES) cells, umbilical cord blood stem cells, organ-specific somatic stem cells (e.g., neural stem cells for ... brain Substantial efforts have therefore been devoted to obtaining more pluripotent stem cell populations, such as bone marrow mesenchymal stem cells (MSCs) or adipose stem cells, for use in ... pluripotent stem cells from spermatogonia in the adult human testis, providing another strategy for obtaining genetically identical stem cells Umbilical cord blood stem/ progenitor cells are associated...

5
456
0

Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 2) pps

Ngày tải lên : 07/07/2014, 01:20

... achieved after transplantation of a variety of different cell types, including ES cells, bone marrow stem cells, endothelial stem cells, and adipose stem cells Bone marrow stem cells in particular ... vehicles for cellular gene therapy (Chap 65) Figure 67-1 Strategies for transplantation of stem cells Undifferentiated or partially differentiated stem cells may be injected directly in the target ... tissue; (2) in vitro differentiation of stem cells followed by transplantation into a damaged organ—e.g., pancreatic islet cells could be generated from stem cells prior to transplantation into patients...

5
316
0

Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 3) pot

Ngày tải lên : 07/07/2014, 01:20

... been targeted for stem cell therapies include spinal cord injury, amyotrophic lateral sclerosis, stroke, traumatic brain injury, Batten disease, and Parkinson's disease In Parkinson's disease, ... development of dyskinesia Transplantation of stem cell derived dopamine-producing cells offers a number of potential advantages over fetal transplants, including the ability of stem cells to migrate ... Multipotent stem cells present in the adult brain can also generate all of the major neural cell types, but highly invasive procedures would be necessary to obtain autologous cells Fetal neural stem cells...

5
365
0

Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 4) pot

Ngày tải lên : 07/07/2014, 01:20

... the organ Imaging techniques are needed to visualize stem cells in vivo after transplantation into humans Fortunately, stem cells can be engineered before transplantation to contain contrast agents ... regenerative medicine and cancer therapies Clin Pharmacol Ther 82(3):252, 2007 [PMID: 17671448] National Institutes of Health: Stem cell information page URL: http://stemcells.nih.gov/index.asp Puceat ... abnormalities with time in culture and are contaminated with mouse proteins These findings have sparked renewed debate about the need to develop new human ES cell lines In considering ethical issues...

5
311
0