22 n glycans are involved in the response of caenorhabditis elegans to bacterial pathogens
Báo cáo y học: "Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection" pot
... underlying an intestine-localized, pathogen-shared response to infection in C elegans Modeling the molecular basis underlying an intestine-localized, pathogen-shared response to infection in C elegans ... marcescens infection These results underline the fact that C elegans mounts distinct responses to bacterial and fungal infection The response of C elegans to infection by S marcescens and P aeruginosa ... that in the context of an interaction-network, their association with the common response gene asp-6 may be an indication of their involvement in intestinal cell necrosis provoked by infection Such...
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Báo cáo khoa học: The starch-binding capacity of the noncatalytic SBD2 region and the interaction between the N- and C-terminal domains are involved in the modulation of the activity of starch synthase III fromArabidopsis thaliana pdf
... presence of any protein band, indicating that the individual SBDs are unable to interact with CD under these experimental conditions To further investigate which region in the D23 protein contains ... tyrosine) in binding site I [22] We have shown that the tryptophan residue involved in binding site II is conserved in the D2 protein (W366); however, a tyrosine residue (Y394) is present in binding ... different roles in protein–protein interaction and polysaccharide binding Analysis of the starch-binding capacity of the individual SBDs has indicated that D2 has the highest binding affinity relative...
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Báo cáo khoa học: Identification of two cysteine residues involved in the binding of UDP-GalNAc to UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) ppt
... Pharmaceutical University) [22, 23], containing a cDNA encoding the insulin signal sequence and the Protein A-IgG binding domain, was inserted into NheI-HindIII digested pcDNA3.1, producing the vector, pInsProA ... several interactions are involved in binding of the UDP portion of the sugar donors to the enzymes [31–37] In GalNAc-T1, hydrogen bonding with Cys212 and Cys214 appears to be predominant interactions ... and a Protein A-IgG binding domain were fused to the resulting N terminus of the sequence The recombinant truncated GalNAc-T1 was then expressed in COS7 cells and the secreted fusion protein...
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Báo cáo y học: "Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer''''s patches in an orally tolerized, collagen-induced arthritis mouse model" ppt
... tolerance induction in indoleamine 2,3-dioxygenase-expressing CD11c+ dendritic cells of tolerized mice The induction of oral tolerance increases the proportion of indoleamine 2,3-dioxygenase (IDO)-expressing ... induction of oral tolerance in the murine CIA model We examined the change in the expression of IDO in CD11c+ DCs of Peyer's patches after repeated oral administration of CII and subsequent induction ... interesting to investigate IDO expression in different subsets of DCs from tolerized mice and to characterize their role in the induction and maintenance of immune tolerance Available online http://arthritis-research.com/content/10/1/R11...
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Báo cáo khoa học: Catalytic activation of human glucokinase by substrate binding – residue contacts involved in the binding of D-glucose to the super-open form and conformational transitions ppt
... located in one of the regions connecting the L- and S-domains, undergoes a large change in the backbone conformation [(Du + Dw) of $ 110°] upon Glc binding, whereas the corresponding change in the ... contacts also change noticeably upon Glc binding (Fig 8B,C) The changes in the interhelical interactions point to a major contribution in the dynamic communication between the L- and S-domains ... fluorescence enhancement induced by Glc binding; (b) to identify the active site residues involved in the binding of Glc to the super-open state (Fig 1C) of this two domain [large (L) and small...
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báo cáo hóa học: " Nogo receptor is involved in the adhesion of dendritic cells to myelin" ppt
... adhesion to myelin, resulting in the selective accumulation of matDCs rather than immDC in the myelin debris-containing lesion This would result in further antigen presentation and activation of ... interaction with myelin in the mouse WT system This is in line with the observation of no change in immune response after EAE was induced in Ngr1/2-/- mice, as well as no difference in the number of CNS ... expression in human DCs This is due to previous findings of functioning NgR1 in the absence of LINGO1 and/or p75NTR and TROY [11,13,14,37], which leads McDonald et al Journal of Neuroinflammation 2011,...
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Báo cáo y học: "The temporal program of peripheral blood gene expression in the response of nonhuman primates to Ebola hemorrhagic fever" ppsx
... TNF-α and NF-κB (Figure 3), providing evidence that the circulating cells are responding to the large amounts of TNF-α that are induced during infection Induction of the NF-κB pathway by TNF-α ... IFNGR1 IFNAR1 IFNG of proinflammatory cytokines, leading in turn to recruitment of macrophages to areas of inflammation, which may contribute to viral proliferation and eventually an overwhelming ... count, increased transcript abundance) refereed research We noted an increase in TNF-α converting enzyme/α-disintegrin and metalloproteinase (ADAM)-17 at days to after infection, peaking at an...
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Tài liệu Temi di discussione: Are there asymmetries in the response of bank interest rates to monetary shocks? pdf
... TD No 340 (October 1998) C GIANNINI, “Enemy of none but a common friend of all”? An international perspective on the lenderof-last-resort function, Essay in International Finance, Vol 214, Princeton, ... in the response of the lending rate to a deviation in the long run relationship between the interest rate on deposits and the interbank rate This result suggests that after the introduction of ... Banking Law; 2) interest rate adjustments, in response to positive and negative shocks, are asymmetric in the short run, but not in the long run, consistently with the idea that in the long run...
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báo cáo khoa học: "The grapevine guard cell-related VvMYB60 transcription factor is involved in the regulation of stomatal activity and is differentially expressed in response to ABA and osmotic stress" ppt
... differences in lengths were found in the first intron and the third exon, which were longer in the grape genes compared to AtMYB60 Expression of VvMYB30 and VvMYB60 in grape tissues and in response ... and R3 repeat, respectively Additional file 2: Phenotypic changes in grapevine plantlets grown in the presence of growing NaCl concentration Pictures were taken one month after the beginning of ... involved in the regulation of the anthocyanin and pro-anthocyanidin biosynthetic pathway, as the accumulation of these flavonoid compounds in fruit tissues is a key determinant of berry and wine quality...
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Risks Involved in the Use of Herbal Products
... pseudoephedrine, and norephedrine (also known as phenylpropanolamine and norpseudoephedrine) These constituents are 14 Risks Involved in the Use of Herbal Products 353 commonly found in over -the- counter ... gastrointestinal tract, and nervous system Digestive complaints, including nausea, are due to the substantive tannin content of the fruit High doses and prolonged use may lead to chronic intoxication; ... from their ability to inhibit phase I and induce phase II carcinogen metabolizing enzymes that initiate carcinogenesis They also inhibit the promotion stage of carcinogenesis by inhibiting oxygen...
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Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc
... the aminopyrimidine ring, are conserved in all ThDP-dependent enzymes One of these, the hydrogen bond between the N1 ¢ atom of the pyrimidine ring of ThDP and the side chain of an invariant glutamate ... molecules of the cofactors ThDP and Mg2+ The ThDP binding sites are located in narrow clefts at the interfaces formed by the PYR domains from one subunit and the PP domains of the other subunit within ... and ScPDC on the other hand involving the C-terminal part of the polypeptide chain (Fig 7) In the latter, differences in the conformation of the loop between Fig Stereo picture of the model of...
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Tài liệu Báo cáo Y học: Identification of a set of genes involved in the biosynthesis of the aminonucleoside moiety of antibiotic A201A from Streptomyces capreolus pdf
... transcription terminator The resulting fragment only contains the initial 67 bp and the final 68 bp of the pur4 coding sequence It was inserted in plasmid pGM9 The resulting construct was introduced, ... similar to known or putative genes that are known or proposed to be implicated in the biosynthesis of the aminonucleoside moiety of puromycin [6–8] Interestingly, their organization is identical to ... cluster, next to this ORF there should be additional genes encoding other proteins implicated in the biosynthesis of the aminonucleoside moiety of A201A Here we report the sequencing of a total of...
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Tài liệu Báo cáo Y học: Granule-bound starch synthase I A major enzyme involved in the biogenesis of B-crystallites in starch granules ppt
... within the GBSSI sequence compared with those of rice and potato The number and position of the introns are unrelated to those present in vascular plant genes and suggest an ancient divergence of ... protein (data not shown) Restoration of amylose synthesis is likely to come as a consequence of the random integration of the wild-type STA2 gene in the nuclear genome of Chlamydomonas Nevertheless, ... depending on the integration site, expression of this integrated wild-type copy of STA2 might vary greatly Indeed integrations in some genomic regions have been reported to trigger silencing of the...
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Đề tài " Axiom A maps are dense in the space of unimodal maps in the Ck topology " doc
... map to Ac The domain B can contain in nitely many connected components However, there are only finitely many connected components which contain points of the orbit of the critical point Indeed, ... simply connected However, if the ω-limit set of the critical point contains intervals, the domain A cannot be connected if we want the domain B to contain finitely many connected components Letting ... compactly contained in Ax , where B x and Ax denote connected components of B and A containing x and Ac denotes a ¯ connected component of A containing the critical point c (i.e B x ⊂ Ax , ¯x is the...
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BRANDS ARE BUILT IN THE CONSCIOUSNESS OF THE RECEIVER, NOT BY THE COMPANY potx
... distinct and, in the long term, stronger brands.” Tough times at There’s a battling brewing among top-ranked global brands Today’s winners can be down for the count tomorrow consultancy Interbrand’s ... responsibility Consumers are demanding that the companies they shop at behave responsibly.” In incontinence, we’ve carried out work long-term to increase openness and information in an area ... tradition-bound chateaux in the Bordeaux region have begun selling their wines as bag -in- box t he ingenuity involved in wiping our behinds has included everything from leaves, rocks and sponges to catalogs...
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Báo cáo khoa học: Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+ Lorenz Schild1 and Georg Reiser2 doc
... occupying binding sites located in the inner and outer mitochondrial membrane [39,40] The binding of ADP stabilizes the matrix conformation of the adenine nucleotide translocator which is known to ... a growing body of information concerning the mechanism of ROS generation by the respiratory chain in mitochondria Complex I and complex III were identified as generators of superoxide anion radicals ... H2O2-dependent oxidation and ⁄ or by decrease in the reduction of GSSG due to permeabilization of the mitochondrial inner membrane, the reduction of GSH concentration indicates decrease in antioxidative...
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Báo cáo khoa học: Factors involved in the assembly of a functional molybdopyranopterin center in recombinant Comamonas acidovorans xanthine dehydrogenase pot
... means for their incorporation into the expressed protein in order to form an active enzyme Proteins functioning in the sulfuration of the molybdopyranopterin cofactor have been identified in D ... terminal sulfur ligand on the Mo, and the incorporation of two [2Fe)2S] centers and an FAD into the recombinant enzyme Therefore, the host organism has to be able to provide these cofactors and the ... function and mechanism of the xdhC gene product in MPT insertion into the molybdoenzymes The finding that XDHAB activity levels are dependent on the level of culture aeration suggests that, in the...
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Báo cáo khoa học: RNA-binding properties of HCF152, an Arabidopsis PPR protein involved in the processing of chloroplast RNA pdf
... been proposed to be involved in the translation of the petD mRNA in addition to RNA processing [20] Function of HCF152 in petB RNA maturation Fig RNA affinities of truncated proteins containing ... involved in the stabilization of the splicing products of the petB intron could be that the protein binds to the UTR region between psbH and petB, and to domain IV of the petB intron The binding ... analyzed the binding of these RNAs using the UV-crosslinking competition method In this method, only a single RNA is radioactively labeled to provide the UV-crosslinking signal when binding the...
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Báo cáo khoa học: Cell death-inducing DFF45-like effector, a lipid droplet-associated protein, might be involved in the differentiation of human adipocytes pdf
... National Natural Science Foundation of China References Billon N, Monteiro MC & Dani C (2008) Developmental origin of adipocytes: new insights into a pending question Biol Cell 100, 563–575 Koutnikova ... temperature in NaCl ⁄ Pi containing 3% paraformaldehyde, permeabilized for 15 in NaCl ⁄ Pi containing 0.1% saponin, then incubated with HA antibody (sc-7392; Santa Cruz Biotechnology, Santa Cruz, ... droplet-targeting proteins, perilipin and fatty acid-binding protein (FABP) are expressed at late and mature stages of lipid droplet formation Interestingly, we found that the mRNA level of adipophilin was...
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Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc
... determined the levels of c-secretase-unrelated ER protein (calnexin) and cytoskeleton protein (tubulin) in these cells as the internal control proteins The calnexin and tubulin levels were found to ... include polyglutamine-expanded huntingtin [18], the tumor suppressor Synoviolin is involved in the degradation of nicastrin gene p53 [19] and Parkin-associated endothelin receptor-like receptor ... that Synoviolin is involved in the degradation of immature NCT and regulates Ab generation Results Accumulation of immature NCT in synoviolin-null cells To investigate whether Synoviolin is involved...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25