21 1 3 b glucans drug delivery and pharmacology

Báo cáo khoa học: A (1ﬁ3)-b-D-glucan recognition protein from the sponge Suberites domuncula Mediated activation of ﬁbrinogen-like protein and epidermal growth factor gene expression pot

... and human (AGP1_HUMAN; Q1 538 9 and AGP2_HUMAN; O1 512 3) (iv) Ficolins: ﬁcolin A and B from pig (FICOLA_PIG; L1 234 4 and FICOLB_PIG; L1 234 5), mouse (FICOLA_MOUSE; AB007 8 13 /b> and FICOLB_MOUSE; AF06 3 217 ), ... XP _3 12 11 /b> 6 .1) and (BACBP_ANGA, CAA04496 .1) , as well as the GLUBP from the lobster Homarus gammarus (GLUBP_HOGAM, CAE47485 .1) and the crayﬁsh Pacifastacus leniusculus (GLUBP_PACLE, CAB6 535 3 .1) ... (TECL5A-TACTR; AB024 737 .1 and TECL 5B_ TACTR; AB024 738 .1) (iii) Angiopoietin: angiopoietin and precursors from mouse (AGP1_MOUSE; O08 538 and AGP2_MOUSE; O35608), bovine (AGP1_BOVIN; O18920 and AGP2_BOVIN;...

Báo cáo Y học: Isolation, enzymatic properties, and mode of action of an exo-1,3-b-glucanase from Trichoderma viride doc

Danh mục: Báo cáo khoa học

... exo -1, 3- b- glucanase Substrate (Gn) Km (mM ) 10 3: Vmax (mmol:min 21: mg 21) 10 3: (Vmax/Km) (min 21 : mg 21) ln (Vmax/Km) G3G G3G3G G3G3G3G G3G3G3G3G G3G3G3G3G3G 16 .5 5.0 1. 9 2.0 2 .1 0 .36 5.5 14 16 18 ... (%) None Ca 21 Mn 21 Mg 21 Zn 21 Hg 21 PHMB EDTA 10 0 97 13 /b> 6 89 83 86 90 81 q FEBS 20 01 Exo -1, 3- b- glucanase from T viride (Eur J Biochem 268) 612 7 in hydrolysis of 1, 3- b- oligoglucosides and curdlan ... a 1, 3 -1, 4-bglucanase and puriﬁed [26] The G3G3G3G3G3G, G3G3G3G3G, and G3G3G3G were prepared by formic acid hydrolysis of curdlan followed by puriﬁcation of 1, 3- b- oligoglucosides [26,27] G3G and...

báo cáo hóa học:" Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs" potx

Danh mục: Hóa học - Dầu khí

... K70R ( 31 . 3) T 215 F (11 .7) V 118 I (25) M184V (76.4) G 333 A (NA) F77L (0) M41L ( 21. 5) Q151M (3. 9) L74V (3. 9) E44A/D (5.8) T 215 Y (33 .3) V75I (0) L 210 W (25.4) K 219 E (11 .7) E44D (0) K 219 Q (7.8) Q151M (3. 9) ... (3. 9) T 215 F (11 .7) T 215 Y (33 .3) RT (NNRTI) (n = 12 ) V108I (25) Y181C (33 .3) G190S (0) P 236 L (0) Y188C (0) V106A (0) K103N (9.6) Y188H/L (16 .6) M 230 L (0) P225H (0) L100I (8 .3) K103N (8 .3) Y188L ... (14 .7) M36I (29.4) I84V (11 .7) M46I (11 .7) PR (n = 34 ) AG N88D/S (8.8) F 116 Y (1. 9) M41L ( 21. 5) F77G (1. 9) I54L (2.9) A71T (8.8) G73S (11 .7) V77I (8.8) V82T (5.8) RT (NRTI) (n = 51) D67N (19 .6)...

Controlled release alginate based microparticulate systems for drug delivery and chemoembolization

Danh mục: Cao đẳng - Đại học

... 19 91) or polyacrylamide (Prabhune and Sivaraman, 19 91) These complexes are not affected by Ca2+ chelators and can be used to both stabilize the gel and reduce its porosity INTRODUCTION A3 .3 Biological ... absorbable in the human body (Heller, 19 84) On the other hand, bio-compatible but non-degradable polymers have the advantage of availability, inertness and physical strength Silicone rubber and ... segment was buckled and ribbon-like (Figure 2b) The ribbon-like conformation is stabilized by intramolecular hydrogen bond between the hydroxyl group and the oxygen atom of the carboxyl group...

Investigation and characterization of splice variations of l type ca2+ channel, cav 1 3, in chick basilar papilla and rat cochlea hair cells iimplications in hearing

Danh mục: Cao đẳng - Đại học

... 1. 2 .1 Alternative splicing of Cav1 .3 gene 10 1. 2.2 Cav1 .3 and cochlea 14 1. 2 .3 Cav1 .3 and other tissues 14 1. 3 Mechanism of calcium dependent inactivation (CDI) 16 1. 4 The organ of Corti 17 1. 5 ... of pAb_ IQ and pAb_Cav1 .3 specific antibodies by immunolabeling and western blot 61 Localization of Cav1.3IQ and Cav1.3IQfull channels in rat cochlear hair cells 64 Summary of Cav1 .3 subunit ... Figure 3. 2 Figure 3. 3 Figure 3. 4 Figure 3. 5 Figure 3. 6 Figure 3. 7 Figure 3. 8 Figure 3. 9 Figure 3 .10 Figure 3 .11 Co-expression of Cav1.3IQfull with different -subunits shows robust CDI but co-expression...

Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Danh mục: Báo cáo khoa học

... FEBS 6 6 21 Crystal structure of human ACMSD 10 11 12 13 /b> 14 15 16 17 18 19 20 S Garavaglia et al compounds in K562 cells but not in normal human lymphocytes Biosci Biotechnol Biochem 64, 11 42 11 46 ... human 6622 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 a-amino -b- carboxymuconate-e-semialdehyde decarboxylase (ACMSD) J Biol Chem 277, 3 516 2 3 516 7 Tanabe A, Egashira Y, Fukuoka SI, Shibata K & ... et al His His His 17 4 Asp 2 91 w1 DHAP B Met 19 5 w1 w 268 DHAP Leu 296 w 51 C1 Trp 19 1 Phe 294 centre into a small pocket delimited by residues Asp2 91, Trp1 91, Met195, Arg47 and the Phe294Pro295-Leu296...

Báo cáo khoa học: Isoquinoline-1,3,4-trione and its derivatives attenuate b-amyloid-induced apoptosis of neuronal cells pdf

Danh mục: Báo cáo khoa học

... 0.064 0.055 0.0 53 0.040 0.474 0 . 13 /b> 7 0.2 01 0 .14 8 0.079 0.079 0 . 216 0 .38 6 0 . 218 0 . 13 /b> 6 0 .11 3 0 .15 1 0.057 0.0 63 1. 9 13 /b> 0. 835 1. 122 2 .36 0 0.684 0.987 0.425 1. 574 1. 30 0 1. 640 1. 811 0. 933 2 .10 4 0.860 ± ± ... 0.0 83 0.006 0.006 0.0 31 0.027 0. 017 0. 014 ± ± ± ± ± ± ± 0. 034 0.024 0. 014 0. 016 0.009 0.007 0.007 ± ± ± ± ± ± ± 0 .15 2 0. 016 0.0 43 0 .15 5 0.0 23 0.025 0.055 ± ± ± ± ± ± ± 0.284 0 .12 7 0.089 0. 31 5 0 .15 2 ... caspase -3, NF-kappaB, p 53 and c-Jun Neurotoxicology 23, 3 51 36 5 16 Misiti F, Sampaolese B, Coletta M & Ceccarelli L (2005) Abeta ( 31 35 ) peptide induce apoptosis in PC 12 cells: contrast with Abeta...

Báo cáo khoa học: Carbohydrate binding sites in Candida albicans exo-b-1,3-glucanase and the role of the Phe-Phe ‘clamp’ at the active site entrance ppt

Danh mục: Báo cáo khoa học

... = b = c = 90° 0.052 (0 . 21) 13 /b> .8 (3. 3) 98.9 (95 .3) 3. 3 (2.6) 30 432 0 . 13 /b> 5 0 .16 8 0. 014 1. 35 0.09 3 211 38 . 23 2.00 (2 .11 –2.00) P2 12 12 1 a = 58.57 b = 64. 63 c = 94.48 a = b = c = 90° 0.069 (0. 43) 17 .4 ... 17 .4 (3. 7) 10 0.0 (10 0.0) 5.4 (5 .3) 25 035 0 .15 4 0.200 0.020 1. 46 0 .11 32 33 334 21 24 30 8 21 22 19 .85 1. 80 (1. 85 1. 80) P2 12 12 1 a = 59.95 b = 65 .32 c = 96.54 a = b = c = 90° 0. 039 (0 .16 ) 14 .2 (4.7) ... 14 .2 (4.7) 99 .3 (94 .1) 3. 2 (2.4) 35 5 63 0 . 13 /b> 6 0 .16 3 0. 012 1. 25 0.08 3 214 24 289 17 19 24 75 38 .19 1. 70 (1. 79 1. 70) P2 12 12 1 a = 58.72 B = 64.40 C = 94.87 a = b = c = 90° 0.074 (0. 63) 14 .1 (2.2) 99.8...

Báo cáo khoa học: NovelN,N¢-diacyl-1,3-diaminopropyl-2-carbamoyl bivalent cationic lipids for gene delivery – synthesis,in vitro transfection activity, and physicochemical characterization docx

Danh mục: Báo cáo khoa học

... 2 :1 +/ 4 :1 liposomes +/ 1: 1 1, 3lb1 200 1, 3lb2 liposomes 60 1, 3lb3 +/ 4 :1 D 80 40 D (nm) 000 Zeta potential (mV) B 400 +/ 2 :1 1,3lb4 800 1, 3lb5 600 400 200 1, 3lb1 20 1, 3lb2 1, 3lb3 20 1, 3lb4 1, 3lb5 ... gene delivery A 400 M Spelios and M Savva C 80 1, 3lb1 1, 3lb3 Zeta potential (mV) 000 60 1, 3lb2 D (nm) 200 1, 3lb4 800 1, 3lb5 600 400 200 40 1, 3lb1 20 1, 3lb2 1, 3lb3 20 1, 3lb4 1, 3lb5 40 60 80 +/ 1: 1 ... derivative: C11H 23 for dilauroyl (1, 3lb1) C13H27 for dimyristoyl (1, 3lb2) C15H 31 for dipalmitoyl (1, 3lb3) C17H35 for distearoyl (1, 3lb4) C17H 31 for dioleoyl (1, 3lb5) Fig Structure of the 1, 3lb derivatives...

Báo cáo khoa học: Tertiary structure in 7.9 M guanidinium chloride ) the role of Glu53 and Asp287 in Pyrococcus furiosus endo-b-1,3-glucanase pot

Danh mục: Báo cáo khoa học

... v2 9.8 2.5 9.6 3. 0 ã ã ã ã 10 )5 10 )4 10 )4 10 )3 3 .3 3.4 1. 1 4.4 ã ã ã ã 10 7 10 5 10 6 10 5 v 2.9 3 .1 1.7 3 .1 ã ã ã ã 10 )4 10 )4 10 )3 10 )4 mutant (Fig 4, insets) Notably, in 7.9 m GdmCl and 40 mm CaCl2, ... (kJặmol )1) mg DDGH2O )1 )1 (kJặmol ặM ) (kJặmol )1) Wild-type D287A E53A E53A D287A 6.7 6.2 6.0 6.2 9.2 5.9 5.6 5 .3 0 . 13 /b> 0 .15 0 .12 0 .15 61. 5 36 .5 33 .9 33 .1 1. 23 0. 91 0.68 0. 83 0 .18 0 .15 ... m )1, 8.6 m )1, 8.4 m )1 and 9.4 m )1 for the wild-type and D287A, E53A and the double mutant, respectively In 7.9 m GdmCl, the acrylamide quenching constants were 13 /b> .0 m )1, 9.9 m )1, 11 .5 m )1 and 10 .3...

Giáo án tiếng anh lớp 5 - UNIT 10 SEASONS AND WEATHER Section B (1-3) Period 53 doc

Danh mục: Mầm non - Tiểu học

... Students’: book, notebook III ACTIVITIES FOR TEACHING AND LEARNING Settlements (1 ) Oral test: (3 ) Ss exercises 3, 4, 3. New lesson TEACHER’S ACTIVITIES STUDENTS’ ACTIVITIES Activity 1: (3 ) Warm up and ... Listen and answer Activity 2:( 10 ’) 1. Listen and repeat a- Pre listen T says about the situation in the 1. Listen and repeat dialogue Look, Listen -Guide Ss use questions: -Look, listen and repeat ... Activity 4 (10 ’) 3. Listen and check - Guide Ss to listen and check - Call some Ss read in front of the class Play cassette times Listening: 3. Listen and check Read sentences Listen and check Peter...

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Giáo án tiếng anh lớp 5 - UNIT 12 DIRECTIONS AND ROAD SIGNS Section B (1-3) Period 61 pdf

Danh mục: Mầm non - Tiểu học

... test: (3 ) Ss exercises 3, 4, New lesson TEACHER’S ACTIVITIES STUDENTS’ ACTIVITIES Activity 1: (3 ) Warm up and review -T ask some questions: Listen and answer Activity 2:( 10 ’) 1. Listen and repeat ... It’s one hour by plane Are we going by bus? Yes, it’s about two hours Some Ss give result Other listen and remark Listen and check: T or F Key: F F T We’re going by plane It’s F about two hours ... ask- Line B answer then change Then Ss practice to say in pair It’s about (10 kilometres) Some pairs practice in front of th class Other listen and remark Activity 4 (10 ’) 3. Listen and check -...

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Giáo án Anh văn lớp 7 : Tên bài dạy : Unit 10 : Health and hygiene. Lesson 3 : B-1 . ppt

Danh mục: Anh ngữ phổ thông

... in the text book ( p :10 3 ) - Write down the answer on the BB, others answer inturn the questions a) Minh has a toothache b) No, he doesn’t, the loudness of the drill scares him c) Because she ... practice aksing answering about you ( work in pairs ) Consolidation Retell the main content of the dialogue Home work - Study the lesson and exercise B1 in the work book ( P: 63 ) - Prepare the new ... 1 Some people physical exercise a to have the tooth out It’s a good ideato see the dentist b to keep fit and loose weight 3. The nurse gave Mike two aspirins...

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Báo cáo khoa học: "B6C3F1 mice exposed to ozone with 4-(N-methyl-Nnitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate showed toxicities through alterations of NF-κB, AP-1, Nrf2, and osteopontin" pdf

Danh mục: Báo cáo khoa học

... 440, 1- 31 4 , 19 94 31 Marsman D NTP technical report on the toxicity studies of Dibutyl Phthalate (CAS No 84-74-2) Administered in Feed to F344/N Rats and B6 C3F1 Mice Toxic Rep Ser 30 , 1- G5, 13 /b> 7 19 95 ... Cho MH Combined treatment of 4-(Nmethyl-N-nitrosamino) -1- (3- pyridyl) -1- butanone and dibutyl phthalate enhances ozone-induced genotoxicity in B6 C3F1 mice Mutagenesis 2002, 17 , 3 31 - 33 6 27 Koren ... control Assoc 19 89, 39 , 672-695 30 NTP Toxicology and Carcinogenesis Studies of Ozone (CAS No 10 028 -15 -6) and Ozone/NNK (CAS No 10 028 -15 -6/ 640 91- 91- 4) in F344/N Rats and B6 C3F1 Mice (Inhalation...

Báo cáo khoa học: "Replication and drug resistant mutation of HIV-1 subtype B'''' (Thailand B) variants isolated from HAART treatment individuals in China" pot

Danh mục: Báo cáo khoa học

... K1 01* EKQ, Y181C, G190A K103N, Y181C K103N, Y181C Y181C K103N, Y181C K101E, Y181C, G190S K103N, Y181C V108FILV K103N, G190A Y188L G190EV - - G190A V1 V2 R5X4 R5 - V3 V4 V5 V6 V7 V8 V9 V10 V 11 V12 V 13 R5X4 ... T 215 Y D67N, K70R, T 215 F, K 219 Q L74V M41L, L74V, T 215 F K65R T69APST M41LM, T 215 Y A62V, K70KN, V75T - T 215 Y K103N, Y181C D67N, K70R, T 215 F, K 219 Q K103N, Y181C V75T V108I, Y181C K103N, Y181C M41L, ... M41L, L74V, T 215 F K101E, Y181C, G190S K65R K103N, Y181C T 215 Y K103N, G190A K70N, V75T Y188L G190A Y181C -: none; bold: lost after culture; bold and italic: emergent after culture; bold and underline:...

Investigation on factors affecting drug delivery using polymers and phospholipids 1

Danh mục: Cao đẳng - Đại học

... Sodium-Loaded Vesicles 90 90 91 91 91 92 92 93 93 93 94 94 94 95 98 10 0 10 2 10 4 10 4 10 6 10 6 10 6 10 6 10 7 10 7 10 7 10 7 10 8 10 8 10 8 10 8 11 0 11 1 11 2 11 7 11 8 12 0 12 0 12 2 12 2 12 2 iv 8.2 .3 Determination of Encapsulation ... 29 30 30 31 33 33 34 34 36 36 36 36 37 38 40 46 47 47 49 49 50 50 ii 3. 2.4 Phase Solubility Studies 3. 2.5 Surface Tension and Contact Angle Measurements 3. 2.6 In vitro Skin Permeation Studies 3. 3 ... and direction for future work REFERENCES LIST OF PUBLICATIONS 12 5 12 5 12 5 12 6 12 6 12 6 12 6 12 8 12 8 13 /b> 1 13 /b> 4 13 /b> 6 14 2 16 7 v SUMMARY Topical drug delivery helps to achieve therapeutic concentrations...

Investigation on factors affecting drug delivery using polymers and phospholipids 3

Danh mục: Cao đẳng - Đại học

... PG-Limonene 0 .1% v/v PG-Limonene 0 .1% v/v, RM β-CD 0. 01 M PG RM β-CD 0. 01 M Mean Flux ± SD (μg/cm2/h) 0 .18 ± 0. 01 0.04 ± 0. 01 0 .11 ± 0. 03 0.49 ± 0 .12 0.90 ± 0 .14 1. 71 ± 0.22 0 .12 ± 0. 01 1.98 ± 0 .35 2.74 ... + PLGA 73: 27 10 10 10 10 50 50 50 50 PLA PLGA 48:52 35 35 - PLGA 73: 27 30 30 - 30 30 Double-layered fiber mats were obtained by fabricating each polymer to form its individual layer and were ... (n =3) 63 c) 14 Buffer pH 12 Water Cumulative HP μg\cm RM β-CD 0.01M-Buffer pH 10 0 10 15 20 25 30 20 25 30 Time (h) d) 10 D: PG, R: PBS D: PG, R: RM β-CD Cumulative HP μg\cm D: RM β-CD 0.01M,...

Climate change as environmental and economic hazard - phần 1.3

Danh mục: Môi trường

... Studies, 3( 3) 17 9 19 5 Allen, K M., 2006 Community-based disaster preparedness and climate adaptation: local capacitybuilding in the Philippines Disasters, 30 (1) 81 – 10 1 Anderson, M B and Woodrow, ... Global Environmental Change, 16 (3) 2 53 – 267 ´ Gallopın, G C., 2006 Linkages between vulnerability, resilience, and adaptive capacity Global Environmental Change, 16 (3) 2 93 – 30 3 Guston, D H., 19 95 ... Common, M., 19 95 Economists don’t read Science Ecological Economics, 15 (2) 10 1– 10 3 Dietz, T., Ostrom, E and Stern, P., 20 03 The struggle to govern the commons Science, 30 2(5652) 19 07 19 12 Dobson,...

Unit 4, Lesson 3: B 1- 5

Danh mục: Tiếng anh

... U M B E R s Tuesday, October 14 th, 2008 Unit 4: BIG OR SMALL Lesson 3: B 1_ 5 I- Vocabulary: The (first) floor: tầng The (sixth) grade: khối lớp * Ordinal numbers: (Số thứ tự) the first = 1st ... 1st * Ask and answer about Thu and Phong: - Which grade/class is Thu in? - She is in grade / class 7C - Where’s her classroom? - It’s on the second floor III- Write: Write about you and your ... Which grade are you in ? Phong: I’m in grade (1) Thu : And which class are you in ? 6A Phong: (2) What about you ? 7C Thu : I’m in grade (3) , class (4) How many floor does your...

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