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2 b risk assessment should be relied on more heavily in decision making as has been proposed in recent bills before congress

Báo cáo khoa học: The subcellular localization of vaccinia-related kinase-2 (VRK2) isoforms determines their different effect on p53 stability in tumour cell lines pdf

Báo cáo khoa học: The subcellular localization of vaccinia-related kinase-2 (VRK2) isoforms determines their different effect on p53 stability in tumour cell lines pdf

Báo cáo khoa học

... Lazo PA (20< /b> 04) Human vaccinia-related kinase (VRK1) activates the 25< /b> 02 < /b> 18 19 20< /b> 21< /b> 22< /b> 23< /b> 24< /b> 25< /b> 26< /b> 27< /b> 28< /b> 29< /b> ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser- 62 < /b> and cooperates ... through a cascade mediated by a casein 1-like kinase Effect on mdm2 binding J Biol Chem 27< /b> 5, 927< /b> 8– 928< /b> 3 50 Dumaz N, Milne DM & Meek DW (1999) Protein kinase CK1 is a p53-threonine 18 kinase which ... the DNA-binding ability of latent p53 protein by protein kinase C is abolished by protein kinase CK2 Biochem J 378, 939–947 69 Kussie PH, Gorina S, Marechal V, Elenbaas B, Moreau J, Levine AJ...
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Báo cáo y học:

Báo cáo y học: "Computer says 2.5 litres - how best to incorporate intelligent software into clinical decision making in the intensive care unit" doc

Báo cáo khoa học

... and Boyd Bayesian network’s original probability assessments were based either on the subjective assessments of two expert clinicians, or on scientific literature, and then updated using machine ... model’s ability to predict fluid requirement can only be as good as the initial clinical assessment This study was conducted in a single centre, and so the model in fact predicts the decisions of ... This would be an interesting addition to future work, as would comparing physician and computer model predictions It will be important to include patient outcome measures as end-points in such a...
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Tài liệu Don’t navigate risky waters without internal auditors: Guidance on leveraging audit analytics for risk assessment pptx

Tài liệu Don’t navigate risky waters without internal auditors: Guidance on leveraging audit analytics for risk assessment pptx

Kế toán - Kiểm toán

... focusing more on risk is that you stop paying attention to things that have been deemed to be risk- free – and that assessment could be wrong, causing you to miss something significant Or, conversely, ... organization and business processes be leveraged to help pinpoint areas of risk for management? And how you become more efficient and effective at pinpointing risk assessments? However, the problem ... determine where to focus audit attention Consider using a risk scorecard to assist with this process 99 Once this has been assessed within an audit program, consideration can be given to determine...
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Key Information on Target Date Funds as Default Investments Should Be Provided to Plan Sponsors and Participants pdf

Key Information on Target Date Funds as Default Investments Should Be Provided to Plan Sponsors and Participants pdf

Quỹ đầu tư

... Contribution Arrangements, 74 Fed Reg 8 ,20< /b> 0 (February 24< /b> , 20< /b> 09) (to be codified at 26< /b> C.F.R pts and 54) Page GAO-11-118 Defined Contribution Plans Nonetheless, TDFs have been the subject of considerable ... return on investment 30 27< /b> .9 25< /b> Average 22< /b> .3 20< /b> 15 12.< /b> 8 10 Gains Losses -5 -10 -15 -20< /b> -25< /b> -30 -35 20< /b> 05 20< /b> 06 20< /b> 07 20< /b> 08 20< /b> 09 Year Source: GAO representation of Morningstar data Note: Morningstar ... also designed based on certain assumptions about contribution rates that may not match what is known about prevailing contribution patterns, or the impact of default contribution rates Each of...
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General Standards – Should be covered in Appendix B Staffing – Experienced financial statement auditors pptx

General Standards – Should be covered in Appendix B Staffing – Experienced financial statement auditors pptx

Kế toán - Kiểm toán

... Procedures Noncompliance with or inadequacies would ordinarily be reported as findings in the Letter of Comment and not impact the peer review rating This is trial version www.adultpdf.com Questions ... Communication Prior Reports Material Misstatements Findings Elements (C3E) Audit Documentation This is trial version www.adultpdf.com Reporting Standards AICPA GAGAS GAAP Disclosure s Opinion on ... SAS, AU  Teams – General, Fieldwork, Reporting ED – Drafts, discussions, agreement This is trial version www.adultpdf.com General General Standards – Should be covered in Appendix B Staffing...
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Beyond Pinterest and Instagram Ten visual social networks that should be on your radarJuly 2012 pot

Beyond Pinterest and Instagram Ten visual social networks that should be on your radarJuly 2012 pot

Quản trị kinh doanh

... wants to be the high end Instagram, Toronto-based start-up 500px wants to be the high-end Flickr The Sydney Morning Herald describes it as being "home to some of the most amazing photos in the ... of 20< /b> 11 /20< /b> 12 < /b> were visual, and how imagery is becoming more important online I summarised the trend in a webinar presentationI did for EyeFor Travel (link here) However, though Pinterest, Tumblr ... Beyond Pinterest and Instagram Ten visual social networks that should be on your radar At Rabbit, we’ve written a lot recently about the growth of the visual web - how the big social...
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Báo cáo lâm nghiệp:

Báo cáo lâm nghiệp: "Environmental risk assessment based on semi-quantitative analysis of forest management data" pptx

Báo cáo khoa học

... region Wald st bi (bi/s(bi)) Altitudinal vegetation zone – Ecological-trophical order estimation The Low Tatras region Wald st estimation Wald st bi (bi/s(bi) )2 < /b> bi (bi/s(bi)) – – – –1 .23< /b> 1 148 .2*< /b> * ... data (Orava region, n = 22< /b> 6) 78.3% Corectness of classification on independent data (Kysuce region, n = 28< /b> 6) 85.7% % of removed timber stock in the forest compartment since the beginning of the analyzed ... the studied regions In the Kysuce region, which has been massively affected mainly by biotic agents in the last decade, the highest probability of critical damage occurrence was associated with older...
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Coastal and Estuarine Risk Assessment - Chapter 2 potx

Coastal and Estuarine Risk Assessment - Chapter 2 potx

Cao đẳng - Đại học

... of action should be compared, in both the long and short term); • Subject to review (measures based on the Precautionary Principle should be maintained so long as scientific information is incomplete ... data and more refined risk assessments, a substance may be deemed as dangerous by the Commission and be banned or restricted The risk assessment methodology that should be used is described in the ... high, one should initiate action even if there is scientific uncertainty.”8 This principle has been increasingly adopted in Europe over recent years, as in the 1987 Ministerial Declaration on the...
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Ecological Risk Assessment for Contaminated Sites - Chapter 2 docx

Ecological Risk Assessment for Contaminated Sites - Chapter 2 docx

Điện - Điện tử

... information must be used with caution Information may not be of high enough quality for risk assessment, it may be so old as to be no longer relevant, or it may have been obtained using inappropriate ... setting? • Have historical data been gathered and assessed? • Has information on probable background concentrations been obtained? • Does the work plan provide a conceptual site model for the baseline ... people living or working near the site, and prior documents describing the site Information that should be included in the site description is listed in Box 2.< /b> 2 © 20< /b> 00 by CRC Press LLC BOX 2.< /b> 2 Information...
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HANDBOOK OFCHEMICAL RISK ASSESSMENT Health Hazards to Humans, Plants, and Animals ( VOLUME 1 ) - PART 2 pptx

HANDBOOK OFCHEMICAL RISK ASSESSMENT Health Hazards to Humans, Plants, and Animals ( VOLUME 1 ) - PART 2 pptx

Cao đẳng - Đại học

... No data 3.4 FW vs 1.0 2.< /b> 0 FW 0.8 FW vs 1.3 FW 0.5 2.< /b> 4 FW vs 0 .2< /b> 10.8 FW 26< /b> 26< /b> 26< /b> 26< /b> 26< /b> 26< /b> 26< /b> 26< /b> 26< /b> 26< /b> 26< /b> Max 12.< /b> 6 FW Max 8 .2 < /b> FW Max 2.< /b> 9 FW 27< /b> 27< /b> 27< /b> 1.0 (0.5 2.< /b> 0) DW 4.9 (2.< /b> 8–7.4) DW ... feathers; contaminated vs 2.< /b> 5–3.7 DW vs 0 .2< /b> 1.5 DW noncontaminated areas Raritan Bay, New Jersey; liver vs salt gland 0 .2< /b> 2.< /b> 7 FW vs 15 .2 < /b> FW © 20< /b> 00 by CRC Press LLC 29< /b> 29< /b> 29< /b> 30, 31 32 < /b> 32 < /b> 32 < /b> 32 < /b> 32 < /b> 29 29< /b> ... effect on embryonic survival 22< /b> 22< /b> 22< /b> 22< /b> Some accumulation in scales and otoliths, but not statistically significant Swimming activity reduced 31% in 96 h LC25 (96 h) LC88 (96 h) 23< /b> 24< /b> 24< /b> 24< /b> Testicular...
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Risk Assessment and Indoor Air Quality - Chapter 2 ppt

Risk Assessment and Indoor Air Quality - Chapter 2 ppt

Cao đẳng - Đại học

... this book before delving more deeply into the subject II THE BEGINNINGS OF HUMAN HEALTH RISK ASSESSMENT Public concern over environmental pollution grew rapidly in the 1960s and 1970s As public health ... for decision making As noted by the Commission on Risk Assessment and Risk Management, many risk assessments in the past estimated risks using hypothetical, nonexistent, maximally exposed individuals ... questions There are and almost always will be substantial scientific uncertainties in environmental risk assessment In addition, making policy and public health decisions using uncertain risk...
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Regional Scale Ecological Risk Assessment - Chapter 2 potx

Regional Scale Ecological Risk Assessment - Chapter 2 potx

Cao đẳng - Đại học

... L1655_book.fm Page 29< /b> Wednesday, September 22< /b> , 20< /b> 04 10:18 AM Port Valdez, Alaska Risk Assessment Endpoints Size INTRODUCTION TO THE REGIONAL RISK ASSESSMENT Table 2.< /b> 3 Summary of the Risk Assessments ... INTRODUCTION TO THE REGIONAL RISK ASSESSMENT Sources L1655_book.fm Page 22< /b> Wednesday, September 22< /b> , 20< /b> 04 10:18 AM 22< /b> REGIONAL SCALE ECOLOGICAL RISK ASSESSMENT Table 2.< /b> 2 Example of Ranking Criteria for ... upon the assessment endpoints are to be considered © 20< /b> 05 by CRC Press LLC L1655_book.fm Page 13 Wednesday, September 22< /b> , 20< /b> 04 10:18 AM INTRODUCTION TO THE REGIONAL RISK ASSESSMENT measured/ estimated...
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Ecological Risk Assessment - Part 2 pdf

Ecological Risk Assessment - Part 2 pdf

Cao đẳng - Đại học

... it may be reasonable to define the kingfishers nesting on a watershed or a lake as an assessment population Continued ß 20< /b> 06 by Taylor & Francis Group, LLC BOX 16.6 (Continued) Defining Assessment ... must be measured and modeled in the assessment Without an unambiguous operational definition of the assessment endpoints, the results of the assessment would be too vague to be balanced against ... legal considerations For example, it would not be reasonable to define the belted kingfishers in a 20< /b> m stream reach as an assessment population if that reach cannot fully support one belted kingfisher...
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Báo cáo y học:

Báo cáo y học: "Could the expression of CD86 and FcγRIIB on B cells be functionally related and involved in driving rheumatoid arthritis" pps

Báo cáo khoa học

... relationship between FcγRIIB expression in autoantibody-mediated disease such as RA merits further exploration Indeed, differential FcγRIIB expression may in uence other B cell functions, including ... activation measured by CD86 expression and levels of FcγRIIB, indicating that the relationship between FcγRIIB expression and B cell activation, especially in the context of in ammatory disease, requires ... Nat Med 20< /b> 05, 11:1056-1058 Radstake TR, Franke B, Wenink MH, Nabbe KC, Coenen MJ, Welsing P, Bonvini E, Koenig S, van den Berg WB, Barrera P, van Riel PL: The functional variant of the inhibitory...
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Báo cáo y học:

Báo cáo y học: " HIV transmission should be decriminalized: HIV prevention programs depend on it" docx

Báo cáo khoa học

... of the above constitute grounds for advocating frequent testing for individuals who might be at risk of contracting HIV, in the hope of attaining earlier diagnoses Yet, the risk of being accused ... law Probably, as well, a per- http://www.retrovirology.com/content/5/1/108 son who throws contaminated blood or needles at someone should be charged with assault, since their intent was most ... relations involves a personal responsibility to know one's partner on much more than a superficial level Finally, let's not confuse the issue of HIV testing and personal responsibility for consensual...
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A study on the bennefits of using portfolios as a means of assessment in the writing development for the third year stdents of english at hanoi pedagogical university no 2

A study on the bennefits of using portfolios as a means of assessment in the writing development for the third year stdents of english at hanoi pedagogical university no 2

Anh văn thương mại

... activities, among which portfolio in writing is an innovative assessment tool Portfolio has been proven to bring about significant improvements in students’ writing skill Portfolio has been made ... learning and teachers’ teaching as both respond to the information it provides Assessment for learning is an ongoing process that arises out of the interaction between teaching and learning Assessment ... REVIEW IN BRIEF II .2 < /b> An overview of assessment II .2.< /b> 1 Definition of assessment II .2.< /b> 2 Reasons for assessing students .5 II .2.< /b> 3 Principles for assessing students...
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