13c6 and c2 positions of the edited purine
Báo cáo khoa học: Biochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus pptx
... with the native state of the protein We then carried out the characterization of the thermal properties of the mutant in comparison with those of PfPNP The results obtained indicate that the substitution ... important for the enzyme stability Finally, the characterization of the thermal properties of the C25 4S ⁄ C25 6S mutant allowed us to propose that the CXC motif in the C-terminal region of PfPNP may ... oxidation-reduction to rescue the possible damage of the other two disulfide bonds The presence of a low percentage of the protein with Cys254 and Cys256 in the reduced form further supports this hypothesis It has...
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Comparing the cultural and linguistic analysis of the English word “meal” and words relating to it in contrast with Vietnamese equivalents.
... mentioned The men, especially the husband and the grandfather, sip alcohol and tell their family members what they see and hear or remind them of right or wrong things in life The others also ... denoting the objects covered by the scope of the notion expressed in the word, and the significative function is the function of expressing the content of the respective notion The function of rendering ... difficult The oldest or the husband of the family sits at the head of the table and others sit in descending order according to age or wherever they like The meal starts when everyone has their own...
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A study of semantic and pragmatic features of the adjective warm and its vietnamese equivalents
... “Introduction” states the rationale of the study, Semantics can be simply defined as the study of meaning It defines the aims, objectives and the significance, presents the is central to the study of communication ... review of the research Chapter 3: “Methodology and Procedures” mentions the method and procedures of the research Chapter 4: “Findings and Discussions” is the main frame of need to understand semantics ... element of the meaning of a word; a description of the characteristic feature of what the word refers to E.g the sense of “grasshopper” is “an insect which can jump high the study, which describes and...
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A contrastive analysis of semantic and pragmatic features of the words denoting birds in english and vietnamese
... recognition of the field And the findings of semantic aspects often borrow the WDBs for not only conveying the denotative as well as analysis of pragmatic aspects of these kinds of words will ... understand their cases of Secondly, English considers the WDB “owl” as the symbol meaning, it is important to consider them in their collocations From of “wisdom” on the basis of their experience and ... pragmatic features of the WDBs The finding of the pragmatic features of the WDBs leads both teachers and learners of study may be in one way or another beneficial to the language English and Vietnamese...
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Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... methods Because the enzymatic activity of PRTFDC1 towards hypoxanthine and guanine is only 0.26% and 0.09%, respectively, of the activity of HPRT, the role of the PRTFDC1 in purine metabolism ... Lys173 interacts with both O6 and N7 (Fig 1C) The 2¢OH of the ribose is hydrogen bonded to the main chain and the side chain of Asp142 (Fig 1C) Both hydroxyl groups of the ribose are involved in ... Asp142, 2¢ and 3¢OH of the ribose and three water molecules with ˚ coordination distances of approximately 2.4 A The phosphate of the GMP is hydrogen bonded to main chain and side chain atoms of amino...
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Tài liệu NEW AND ORIGINAL THEORIES OF THE GREAT PHYSICAL FORCES doc
... position at the present day The present theories of the transmission of light and sound; of the production of winds, and sun-spots, and of the method of development and dissemination of heat, are ... except in the direction of other spheres These theories throw new light upon the character and extent of the atmosphere of the moon and planets, and the consequent availability of those and other ... intimate and inherent nature of those forces? Do they, or either of them, belong to the domain of the supernatural? Are they the products of some supreme force, or forces, heretofore unappreciated? The...
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Tài liệu STRATIGRAPHY AND AMMONITE FAUNA OF THE VOLGIAN AND BERRIASIAN ROCKS OF EAST GREENLAND ppt
... regards as the equivalent of thc npper part of t h e Portland Beds of southern England If, with ARKELL (1946, pp 24-28), we place the Portland Beds in the upper part of the Lower Volgian, they, the ... whorls of Tollia pnyeri Bitween 360 and 370 m, on the same flank of the moontain, the writer found similar doggers and platy-weathering sandstones, which contained occasional exarnples of Surifes and ... but further than this I am not prepared to go The dip of the rocks exposed in the 17all~gsides is often vcry nearly 1v Stratigraphy and Anr~noniteFauna of East Greenland 13 the same as the gradient...
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Tài liệu A Dissertation on the Medical Properties and Injurious Effects of the Habitual Use of Tobacco pptx
... cause of offence In these habits we resemble the Aborigines of our country They load their huge pipes with the dried leaves of this plant, and when lighted, they breathe the dark cloud of smoke ... men void of understanding; capable of soothing the sorrows of the afflicted, of healing the wounds of the spirit, and assuaging the anguish of a broken heart But how it fulfils these desirable indications, ... form or other, either to ease the pains of dyspepsia, to allay the horrors of tedium vitæ, or to drown the anguish of a guilty conscience And may not many of these patients say to those of the Faculty,...
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Tài liệu The Dynamic Retention Model for Air Force Officers- New Estimates and Policy Simulations of the Aviator Continuation Pay Program doc
... component to the model of the choice of the length of stay The decision depends on the value of the unobservable taste We can now construct the probability of observing a series of stay decisions ... using the maximum of the expected value of the two coin flips—$0.50— rather than the expected value of the maximum—$0.75.) This approximation resulted in a model that the computer hardware and software ... Comparing the Dynamic Retention Model and the Annualized Cost of Leaving Family of Models 15 The key difference from the DRM is that the ACOL is computing the maximum of the expected values rather...
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Tài liệu Static and Dynamic Analysis of the Internet’s Susceptibility to Faults and Attacks docx
... characteristics of the Internet; , Ko and DIKo are defined as the average diameter, K, and DIK of the original networks and df , Kf and DIKf denote the diameter, K, and DIK after 10% of the nodes are ... meaningful The other metric, S, is defined as the ratio of the number of nodes in the giant connected component divided by the total number of nodes One might notice the different characteristics of the ... snapshots of the real Internet topology.1 On the other hand, [42], [43] have shown that the clustering coefficient of the Internet has been growing and that the average diameter of the Internet...
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Tài liệu Báo cáo khoa học: A facile method for expression and purification of the Alzheimer’s disease-associated amyloid b-peptide pdf
... understanding of the structure of both the Ab monomer and its various assemblies could help in the design of new therapeutic strategies targeted at preventing the formation or ameliorating the activity ... increases the cost of the purification, and the require1276 ment for HPLC increases the length and complexity of the purification procedure Moreover, as with the studies by Lee et al [21] and Subramanian ... Subramanian and Shree [42], there was no rigorous assessment of the purity of the product or the correctness of the sequence In contrast, the purification protocol that we have developed is quick and...
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Tài liệu Báo cáo khoa học: Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain – hints from 15N-NMR relaxation studies pdf
... residues and hence does not conflict with the global interpretation of the data With the exclusion of the N-terminal octapeptidyl and C-terminal nonapeptidyl fragments of Glu17, Leu34 and Lys46, the ... Fig The localization of the experimental points in Fig along the correlation line is directly related to the distribution of the energy between the overall tumbling and the internal mobility, and ... and Ala60–Gln67), together with those from Arg58 and Gln59 in the C-terminal end of helix III, are located apart from the major cluster, towards the lower intercept of the theoretical curve and...
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Tài liệu Báo cáo khoa học: Molecular modeling and functional characterization of the monomeric primase–polymerase domain from the Sulfolobus solfataricus plasmid pIT3 doc
... a4-helix to the b4 strand and the b9 strand to the b10 strand at the bottom of the Zn-stem loop in the pRN1 prim–pol structure However, because the Zn-stem loop is a fairly self-standing structure ... 70 and 80 °C between 190 and 260 nm with a step increase of 0.2 nm, and a bandwidth of nm Thermal stability of Rep245 was measured by incubating the protein at 60, 70 and 80 °C for 30 and then ... the two-metal-ion mechanism of both RNA and DNA synthesis [17] In a previous study, we reported the findings of an analysis of the complete sequence of the cryptic plasmid pIT3 isolated from the...
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Tài liệu Báo cáo khóa học: Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation 2 process of onconase pdf
... (M23L) by the addition of AAP, as described in the Materials and methods Completion of the hydrolysis was confirmed by the disappearance of the (Met1)-ONC (M23L) signal in the MALDI-TOF mass spectra ... analyzed by MALDI-TOF MS The addition of the protease is considered the zero time point The relative intensities of the peaks from the mass spectra were used to calculate the fraction of Pyr-ONC (M23L), ... simultaneously interacts with the main phosphate of the substrate [32] The closer positioning of the N-terminus to the main protein body is essential for the activity and, together with the 87–104 disulfide...
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Tài liệu Báo cáo khoa học: The structure and biological characteristics of the Spirochaeta aurantia outer membrane glycolipid LGLB pdf
... Fragments of HSQC and HMBC spectra of compound Labels illustrate assignment of the amide linkage between the amino group of Asp and the carboxyl group of GalA residue E Scheme The structures of oligosaccharides ... monosaccharides present in the products and were identified, and the ratio of structures and was close to : All chemical shifts remained mostly unchanged with the exception of H/C-2 and H/C-3 of the glycerol ... because of the existence of branches in the molecule Similarly, the tandem MS was conducted for the doubly charged ion at m/z 1180.25 (data not shown) and the mass spectral data fully agree with the...
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Tài liệu Báo cáo khoa học: Structure and membrane interaction of the internal fusion peptide of avian sarcoma leukosis virus pdf
... binding of NBD-IFP–wt at pH 7.4 and 37 °C Increased intensity and the blue-shift of fluorescence of NBD attached to the N-terminus of the peptide indicate embedding of the peptide in the apolar ... of for IFP–wt) and the shape of Ix/x vs x plot Specifically, the initial slow rise of the latter plot (from x ¼ 1) reflects that the self-association of the peptide is not tight (on the scale of ... the angle of insertion of the FP molecules into the bilayer || and ^ represent parallel and perpendicular polarized light, respectively The bottom panel displays the result of deconvolution of...
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Tài liệu Báo cáo khoa học: Bioinformatic and enzymatic characterization of the MAPEG superfamily doc
... the six MAPEG families and three further groups (Insect, E.coliMGST cluster and SynMGST cluster) A major subgrouping is visible with MGST1, PGES and Insect in the upper part of the tree and the ... that the origin of these forms dates back to before the occurrence of vertebrates, i.e more than 500 mya This dates the differentiation of the MAPEG forms back to the late Cambrian multiplicity of ... from the gel, yielded the expected sequence The partially purified protein constitutes a major part of the preparation and therefore the specific activities measured will be close to those of the...
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Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
... ecdysis of an old cuticle and deposition of the components of a new cuticle that are synthesized in the hypodermis and are secreted across the hypodermal membrane into the space between it and the ... staining), and that the inhibition of PPasecatalyzed PPi hydrolysis by these inhibitors, is likely to prevent the synthesis of the new cuticle from the hypodermis and/ or ecdysis of the old cuticle ... of individual components were varied as indicated for the determination of Mg2+ and pH dependent rAsPPase activity The amount of Pi liberated from the hydrolysis of PPi during the course of the...
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Tài liệu ECONOMIC, ENVIRONMENTAL AND ENERGY ASSESSMENT OF THE TURIN-LYON HIGH-SPEED RAIL pdf
... partridges and wolves) and a very rich diversity of flower The first HSR proposal dates back to the end of the eighties, and soon after the opposition in the Susa Valley started In 2011, the new ... villas, churches and abbeys, castles and fortresses, which attract thousands of tourists every year At the time of the Romans, the alpine crossovers of the valley acquired strategic and military ... go from one end of the country to the other, taking real advantage of the high speed (they tend to use the air services instead) A study commissioned by the Mountain Community of the Susa Valley...
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Tài liệu Báo cáo Y học: Role of electrostatics in the interaction between plastocyanin and photosystem I of the cyanobacterium Phormidium laminosum ppt
... investigated the dependence of the secondorder rate constant of the overall reaction, k2, on both NaCl and MgCl2 concentration Information about the thermodynamic parameters of the transition ... between the thermodynamics of the NaCl and MgCl2 dependencies Figure 5A–C shows DHà and –TDSà at 298 K plotted against the square root of ionic strength (using MgCl2) for wild-type, K53A and R93E The ... reaction steps, not for the interaction of macromolecules in solution Furthermore, the magnitude (but not the sign) of the thermodynamic parameters of activation measured with the same experimental...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose