01 inflammation aging and cancer friend or foe
INFLAMMATION, CHRONIC DISEASES AND CANCER – CELL AND MOLECULAR BIOLOGY, IMMUNOLOGY AND CLINICAL pdf
... debris from the battle field and to reconstruct and repair the host and resolve or terminate inflammation 5 Inflammation, Aging and Cancer: Friend or Foe? Stimuli (Stressor) Immune system Neuroendocrine ... behaviors) (Blum et al, 2011 , Braun and Marks 2010 , Del Fabbro et al, 2011 , Elamin 2011 , Hall et al, 2011 , Khatami 2011 a, b, Lukaszewicz and Payen 2010 , Lyman 2011 , Ranmsdale et al, 2011 , Suzuki ... potential, and increased growth signals for tumor growth and angiogenesis [Reproduced from Khatami 2008, Exp Opin Biol Ther, 2008 with permission] Inflammation, Aging and Cancer: Friend or Foe? Unresolved...
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Báo cáo y học: "Progress and Challenges in the Understanding of Chronic Urticaria" pptx
... urticaria and lymphocytes from control donors with phorbol 12 myristate 13 acetate (PMA)- Ferrer and Kaplan, Progress and Challenges in the Understanding of Chronic Urticaria ionomycin and found ... have basopenia31 and hyporesponsiveness to anti-IgE suggested by in vivo desensitization.32 For that purpose, we examined the response of basophils of healthy donors, atopic donors, and patients ... receptor and, to a lesser degree, anti-IgE Such sera release histamine, leukotrienes, and IL-4 from donor basophils However, stimulation of T lymphocytes releases both IL-4 and IFN-c, and the...
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Báo cáo y học: "urgical correction of unsuccessful derotational humeral osteotomy in obstetric brachial plexus palsy: Evidence of the significance of scapular deformity in the pathophysiology of the medial rotation contracture" ppt
... CT or positional MRI imaging, posterior glenohumeral capsulorrhaphy was performed The same surgeon performed all surgical procedures (RKN) Results The preoperative and postoperative Mallet scores ... External rotation Hand to Neck Hand to Spine Hand to Mouth Hand to Mouth angle Supination angle Total Mallet Abduction External rotation Hand to Neck Hand to Spine Hand to Mouth Hand to Mouth angle ... process and the medial margin of the acromion rapidly separating, and the distal segment moving both inferiorly and posteriorly The distal acromio-clavicular triangle becomes normalized, and so...
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báo cáo khoa học: "Update in the management of chronic lymphocytic leukemi" ppt
... hematologist or oncologist has access to commercial laboratories which can perform adequate FISH testing FISH should be performed before making treatment decisions in the upfront or relapsed setting, and ... were similar OR and CR rates were similar for PR (79%, 30%) and PCR (91%, 41%), but median PFS was significantly shorter for PR (12 months) compared to PCR (31 months) These results supported previous ... features revealed OR and CR of 94% and 69%, respectively, with OR 77% and CR 54% in 13 patients with del(17p13) Grade 3–4 neutropenia and thrombocytopenia were observed in 71% and 42% of patients,...
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Báo cáo y học: "Occipital peripheral nerve stimulation in the management of chronic intractable occipital neuralgia in a patient with neurofibromatosis type 1: a case report" pot
... data, and wrote and edited the manuscript OC was a major contributor to reviewing and editing the manuscript EDS contributed to the review and editing of the manuscript All authors read and approved ... guidance and fluoroscopy The C1-C2 interspace, which serves as a key fluoroscopic landmark for occipital peripheral nerve stimulation, and the dens are easily identifiable assessments were the short ... individuals and >15 mm in the greatest diameter in postpubertal individuals; (2) two or more neurofibromas of any type or one plexiform neurofibroma; (3) freckles in the axillary or inguinal...
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Báo cáo y học: " Young adult obese subjects with and without insulin resistance: what is the role of chronic inflammation and how to weigh it non-invasively" docx
... the midpoint between the lower border of the rib cage and the iliac crest MS was defined according to the revised Adults Treatment Panel III (2 001) , and three or more criteria were considered: ... FC, MND, CD and PF helped to draft the manuscript TM and TG performed ultrasound TG participated in the design of the study and performed the statistical analysis All authors read and approved ... cut-off ( >or = 1.95 as insulin resistant) [16] Exclusion criteria were a history of infectious chronic diseases including hepatitis B and C, neoplastic and/ or haematological diseases, autoimmune and...
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Báo cáo y học: " Comparison of the efficacy of lamivudine and telbivudine in the treatment of chronic hepatitis B: a systematic review" pdf
... independently by both authors (S S Zhao and L H Tang) using a pre-designed data extraction form and the information subsequently was entered into Review Manager (RevMan 5.0) Information was extracted ... cause more adverse events or not Creatine kinase (CK) elevation Five studies[6-8,10,11] reported Grade or CK elevations rate at the end of one-year treatment According to chi-squared statistic and ... events were more for patients who received telbivudine than for those who received lamivudine, and increased with the prolonged treatment Especially, Grade or increased CK occurred more frequently...
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Báo cáo y học: "The utility of the mannitol challenge in the assessment of chronic cough: a pilot study" pot
... respiratory symptoms All subjects had normal spirometry, were non-smokers and had < 10 pack year history Ethical approval for the study was given by the Leicestershire, Northamptonshire and Rutland ... intra-class correlation and presented as Bland-Altman plots Receiver-operator curves were generated for mannitol C2 and C5 Correlations were made between the mannitol challenge and other cough ... C5 had a sensitivity of 69 and 62% and specificity of 69 and 81% respectively (Figure 2) Bland-Altman plots for the within subject repeatability of the mannitol C2 and C5 are as shown (Figure...
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Báo cáo y học: "Ultra-low microcurrent in the management of diabetes mellitus, hypertension and chronic wounds: Report of twelve cases and discussion of mechanism of action"
... dermal fibroblasts and U937 cells to secrete transforming growth factor-β1, a major regulator of cell-mediated inflammation and tissue regeneration (29) Insulin resistance plays a major role in the ... red and inflamed up to and including the medial malleolus The lateral aspect of the great toe and second toe turned black Laboratory investigation revealed elevated blood glucose (17.9 mmol/L) and ... http://www.medsci.org Int J Med Sci 2010 , patient underwent a medial forefoot amputation as part of her management Within 28 days after surgery, the 4th and 5th toes become discolored, dusky purple and black...
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Báo cáo y học: " Two-stage procedure in the treatment of late chronic hip infections spacer"
... radiological and laboratory evidence that infection has been overcome with an ESR and CRP levels returning to normal values Antibiotic Loaded Cement The use of antibiotic loaded cement (ALC) in the form ... components and taking at least five tissue samples for bacteriologic and histologic assessments, the acetabular component is cemented loosely and femoral fixation is achieved by means of a press-fit or ... length and joint mobility, minimising soft-tissue contracture and scarring, and facilitating second-stage reimplantation and therefore, should be used as the first option of treatment for late...
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Báo cáo y học: "The Geography of Chronic Obstructive Pulmonary Disease Across Time: California in 1993 and 1999"
... squares (GLS) estimators are available for this purpose and provide unbiased estimates of effects and diagnostics for this form of correlated measurement error [9, 10, 11, 12] Moran’s “I” statistic ... Medical Information Reporting for California System [8] According to HDD, there were approximately 3,664,629 million patient records available in 1993, and 3,775,711 million patient records available ... Beverage Commission information from 1993 and 1999 We collected data from three types of outlets: restaurants, bars and off-premise stores (e.g., liquor stores, grocery stores, etc) With few exceptions,...
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Impact of chronic disease on quality of life among the elderly in the state of São Paulo, Brazil: a population-based study pptx
... hypertension, osteoporosis, and stroke), divided into categories of either “reporting” or “not reporting” the disease • Number of morbidities reported, in five categories: not presenting any morbidity; ... presenting three or four; and presenting five or more • Demographic and socioeconomic variables: gender (male/female); three age categories: 60–69 years of age, 70–79 years, 80 years or more; and education: ... compared to the scores for individuals with no morbidities For two chronic conditions, mean scores were significantly lower on all scales, except for role-emotional For three or more conditions,...
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Continuing Education Programmes for Health Care Providers in the Field of Prevention of Chronic Diseases pdf
... hospital organization and procedures, and behaviour* related to health and disease, so that they (and their families) understand their disease and their treatment, collaborate with each other and ... or service problems and objectives* · assign to each problem adequate learning* time For further information, refer to the WHO educational handbook for health personnel Geneva, World Health Organization, ... hospital and other health care settings, organizational information, and behaviour* related to health and illness It is designed to help patients and their families understand the disease and the...
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báo cáo hóa học: " Physical activity as a mediator of the impact of chronic conditions on quality of life in older adults" pptx
... to obtain ordinal summary scores for Reference group in all analyses Musculoskeletal disorders (n = 12,858): arthritis or rheumatism, fibromyalgia, or back problems Respiratory disorders (n = ... conditions in older adults (including musculoskeletal disorders, cardiovascular disorders, respiratory disorders, diabetes, urinary or bowel disorders, and strokes) We specifically hypothesized that those ... One or more Chronic conditions (n = 17,314) Respiratory disorders (n = 2,722) Musculo- skeletal disorders (n = 11,473) Cardio- vascular disorders (n = 10,741) Diabetes (n = 2,754) Urinary or bowel...
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Báo cáo y học: "Role of pathophysiology of patellofemoral instability in the treatment of spontaneous medial patellofemoral subluxation: a case report" docx
... patellofemoral instability in the treatment of spontaneous medial patellofemoral subluxation: a case report Journal of Medical Case Reports 2010 4:148 Author details Ankara Numune Education and Research ... Department of Orthopedics and Traumatology, Erzincan State Hospital, Erzurum, Turkey Authors’ contributions EA and FY analyzed and interpreted our patient’s data, performed the surgery and contributed ... patella Am J Sports Med 2007, 35(7):1180-1187 Brinker MR, O’Connor DP, Flandry F, Hughston J: Diagnosis and surgical correction of medial patellar subluxation Oper Tech Sports Med 2 001, 9:183-189...
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Báo cáo y học: "Metaplastic ossification in the cartilage of the bronchus of a patient with chronic multi-drug resistant tuberculosis: a case report" potx
... pre-operative and post-operative management of our patient and in drafting and writing the manuscript All authors read and approved the final manuscript Acknowledgements This research was supported in ... bronchial lumen and wall The stimulation caused by this chronic inflammation might have led to the metaplastic transformation of the cartilage Eum et al Journal of Medical Case Reports 2010 , 4:156 ... Seoul, Republic of Korea, 3Department of Thoracic Surgery and Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea and 4Tuberculosis...
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báo cáo khoa học:" Development and validation of a short version of the Assessment of Chronic Illness Care (ACIC) in Dutch Disease Management Programs" doc
... with categories defined as: 0-2 (little or no support for chronic illness care); 3-5 (basic or intermediate support for chronic illness care); 6-8 (advanced support); and 9-11 (optimal, or comprehensive, ... 20(6):64-78 MMWR: Resources and Priorities for Chronic Disease Prevention and Control 1994 Morbidity and Mortality Weekly Reports 1997, 46(13):286-7 Jacobs RP: Hypertension and Managed Care American ... Desai MM, Zhang P, Hennessy CH: Surveillance for Morbidity and Mortality among Older Adults–United States, 1995-1996 Morbidity and Mortality Weekly Reports 1999, 48(8):7-25 Renders CM, Valk GD,...
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Báo cáo y học: " Allergic inflammation does not impact chemical-induced carcinogenesis in the lungs of mice" pdf
... with cancer formation and progression However, in contrast to a generalized effect of any type of inflammation on cancer formation, it is more probable that specific cellular, humoral, and transcriptional ... lung cancers is attributed to other genetic and environmental factors, such as occupational or domestic exposure to gases, fumes, or irritants and inherited somatic mutations or genetic polymorphisms ... chronic inflammation caused by smoking and/ or in the context of COPD [12] can induce or promote lung cancer formation and progression [33] In this regard, observations of increased lung cancer...
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Báo cáo y học: " Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma" potx
... LPA levels and LPA receptors to airway or lung inflammation and injury We have recently shown that LPA was constitutively present in BAL fluids from normal and asthmatic subjects and segmental ... less LPA1 and LPA2 receptors in LPA1+/ - and LPA +/- mice reduce LPA-induced inflammation in lung and that LPA1+/- and LPA2+/- mice are useful models for investigating role of LPA receptors in lung ... intervals and then incubated with a rabbit horseradTable 1: Primers for mouse LPA receptors and COX-2 LPA1 Forward: 5'-TCAACCTGGTGACCTTTGTG-3' Reverse: 5'-GGTCCAGAACTATGCCGAGA-3' LPA2 Forward:...
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Báo cáo y học: " Regional differences in the pattern of airway remodeling following chronic allergen exposure in mice" pptx
... superior and inferior portions The superior half of the left lobe was subjected to a sagittal cut The superior and inferior portions were embedded in the same tissue block with extreme inferior and ... 10% formalin with a pressure of 25 cm H2O, ligated at the trachea, and fixed in 10% formalin for 24 hours Following fixation, the left lung was isolated and bisected into superior and inferior ... the total band area for each band depth Figure malin Depiction of left lobe following inflation and fixation with forDepiction of left lobe following inflation and fixation with formalin The...
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