... attacks / bonds with the positive center BIMOLECULAR NUCLEOPHILIC SUBSTITUTION REACTION (SN2) Stereochemistry of SN2 reactions • The nucleophile attacks from the back side / the side directly opposite... UNIMOLECULAR NUCLEOPHILIC SUBSTITUTION REACTION (SN1) Note: slow step is rate-determining step 10 11 Stereochemistry of SN1 reactions 12 However, few SN1 reactions occur with complete racemization 13 Factors... carbons from which atoms are eliminated 28 BIMOLECULAR ELMINATION (E2) Strong base 29 30 Stereochemistry of E2 reactions • Anti-elimination is highly favored in an E2 reaction groups / atoms