English Vocabulary Flash Cards @ englishpdf.com and englishteststore.com File 157 desistance (n) Cessation despair (n) Utter hopelessness and despondency desperado (n) One without regard for law or life desperate (adj) Resorted to in a last extremity, or as if prompted by utter despair despicable (adj) Contemptible despite (prep) In spite of despond (v) To lose spirit, courage, or hope despondent (adj) Disheartened