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A comprehensive survey of alternate splicing across 42 eukaryotes so as to gain insight into how spliceosomal introns are recognized.
Thông tin tài liệu
A comprehensive survey of alternate splicing across 42 eukaryotes so as to gain insight into how spliceosomal introns are recognized.
Ngày đăng: 14/08/2014, 08:20
Xem thêm: Báo cáo y học: "Cross-kingdom patterns of alternative splicing and splice recognition" docx
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Mục lục
All eukaryotes exhibit splice variation
CE and RI prevalence vary by kingdom and by intron length
Variably spliced regions exhibit size constraints
Most splice variants are not functional
Retained introns are associated with weak splice sites
Splice variation reveals mechanisms of splice site recognition
Evolutionary implications of splice variation
Testing retained introns for evidence of selection at the codon level
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