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A SEARCH FOR
ANTIBACTERIAL AGENTS
Edited by Varaprasad Bobbarala
A Search for Antibacterial Agents
Edited by Varaprasad Bobbarala
Published by InTech
Janeza Trdine 9, 51000 Rijeka, Croatia
Copyright © 2012 InTech
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Technical Editor Teodora Smiljanic
Cover Designer InTech Design Team
First published August, 2012
Printed in Croatia
A free online edition of this book is available at www.intechopen.com
Additional hard copies can be obtained from orders@intechopen.com
A Search for Antibacterial Agents, Edited by Varaprasad Bobbarala
p. cm.
ISBN 978-953-51-0724-8
Contents
Preface IX
Chapter 1 Relationships Between Chemical
Structure and Activity of Triterpenes Against
Gram-Positive and Gram-Negative Bacteria 1
A. G. Pacheco, A. F. C. Alcântara, V. G. C. Abreu
and G. M. Corrêa
Chapter 2 Flower Shaped Silver Nanostructures:
An Efficient Bacteria Exterminator 25
Subash Chandra Sahu, Barada Kanta Mishra
and Bikash Kumar Jena
Chapter 3 Lutamide, a New Ceramide
Isolated from the Leaves of Ficus lutea 41
Herve Martial Poumale Poumale
Chapter 4 Antibacterial Modification of
Textiles Using Nanotechnology 47
Moustafa M. G. Fouda
Chapter 5 Metal Complexes as Antimicrobial Agents 73
Marcela Rizzotto
Chapter 6 Dendrimers as Antibacterial Agents 89
Metin Tülü and Ali Serol Ertürk
Chapter 7 Selected Factors Determining the Content of Lactoferrin,
Lysozyme and Immunoglobulins G in Bovine Milk 107
Jolanta Król, Aneta Brodziak,
Zygmunt Litwińczuk and Joanna Barłowska
Chapter 8 The New About Congenital Antimicrobial Defense
of Some Epithelial Tissues – Vaginal Mucosa and Hair 125
Arzumanian Vera, Malbakhova Ekaterina and Vartanova Nune
VI Contents
Chapter 9 Novel Anti-Microbial Peptides of Xenorhabdus
Origin Against Multidrug Resistant Plant Pathogens 147
András Fodor, Mária Hevesi, Andrea Máthé-Fodor,
Jozsef Racsko and Joseph A. Hogan
Chapter 10 Metal Complexes as Prospective Antibacterial Agents 197
Joshua A. Obaleye, Adedibu C. Tella and Mercy O. Bamigboye
Chapter 11 Bacteriostatic Agents 219
Marzieh Rezaei, Majid Komijani and Seyed Morteza Javadirad
Chapter 12 New Improved Quinlone Derivatives Against Infection 235
Urooj Haroon, M. Hashim Zuberi, M. Saeed Arayne
and Najma Sultana
Chapter 13 Biocompatibility and Antimicrobial
Activity of Some Quaternized Polysulfones 249
Silvia Ioan and Anca Filimon
Chapter 14 The Design of Bacteria Strain Selective
Antimicrobial Peptides Based on
the Incorporation of Unnatural Amino Acids 275
Amanda L. Russell, David Klapper, Antoine H. Srouji,
Jayendra B. Bhonsl, Richard Borschel, Allen Mueller
and Rickey P. Hicks
Chapter 15 Synthesis, Spectral, Magnetic, Thermal and Antimicrobial
Studies on Symmetrically Substituted 2, 9, 16, 23-tetra-
phenyliminophthalocyanine Complexes 305
M. H. Moinuddin Khan, K. R. Venugopala Reddy and J. Keshavayya
Chapter 16 Antisense Antibacterials:
From Proof-Of-Concept to Therapeutic Perspectives 319
Hui Bai and Xiaoxing Luo
Preface
This book contains precisely referenced chapters, emphasizing antibacterial agents
with clinical practicality and alternatives to synthetic antibacterial agents through
detailed reviews of diseases and their control using alternative approaches. The book
aims at explaining bacterial diseases and their control via synthetic drugs replaced by
chemicals obtained from different natural resources which present a future direction
in the pharmaceutical industry. The book attempts to present emerging low cost and
environmentally friendly drugs that are free from side effects studied in the
overlapping disciplines of medicinal chemistry, biochemistry, microbiology and
pharmacology.
Varaprasad Bobbarala
Chief Scientist at Krisani Biosciences
India
[...]... aeruginosa Table 3 Bactericidal activity of triterpene derivatives - Ref Takechi & Tanaka, 1992 Takechi & Tanaka, 1992 Takechi & Tanaka, 1992 Takechi & Tanaka, 1992 Takechi & Tanaka, 1992 Takechi & Tanaka, 1992 Hichri et al., 2003 12 A Search for Antibacterial Agents Compound Activity against Grampositive bacteria Activity against Gramnegative bacteria 3β-O-Acetate β-amyrin (118) S aureus E coli and P aeruginosa... et al., 2008 Manguro et al., 2011 Maesa lanceolata B subtilis, E faecalis, S aureus, and S pneumoniae E coli, P aeruginosa, and V cholera Manguro et al., 2011 Maesa lanceolata E faecalis and S pneumoniae S typhi and V cholera Manguro et al., 2011 Maesa lanceolata B subtilis S typhi and V cholera Manguro et al., 2011 Drypetes laciniata Clematis ganpiniana Clematis ganpiniana Clematis ganpiniana Clematis... 1β,2β,3β–Trihydroxy-urs-12-ene-23-oicrhamnoside (52) Commiphora glandulosa Erythrodiol (53) 1β,3β-Dihydroxyurs-12-en-27-oic acid (55) 22β-Acetyl lantoic acid (56) Myricana elegans Myricana elegans Carophora coronata Lantana camara Lantic acid (57) Lantana camara 22β-Acetoxylantic acid (58) Lantana Camara Taraxast-20-ene-3β-ol (59) Lupeol (65) Saussurea petrovii Saussurea petrovii Saussurea petrovii Saussurea petrovii Saussurea petrovii... and Tables 2 and 3, 90% of them exhibit activity against Gram-positive bacteria and 60% of them exhibit activity against Gram-negative bacteria These results indicate higher resistance of Gram-negative Bacteria to the triterpenes Vegetal species Activity against Gram-positive bacteria Dillenia papuana Dillenia papuana Dillenia papuana Dillenia papuana Dillenia papuana Cambretum imberbe B subtilis and... Shaped Silver Nanostructures: An Efficient Bacteria Exterminator Subash Chandra Sahu, Barada Kanta Mishra and Bikash Kumar Jena* Institute of Minerals and Materials Technology, Bhubaneswar, Orissa India 1 Introduction Materials in nanoscale range have dominated several areas of engineering science and technology In the area of biotechnology nano materials have been used increasingly in biomedical analysis,... pneumoniae Umbellatin α (142) B cereus and B subtilis - Mallavadhani et al., 2004 Mallavadhani et al., 2004 Kazakovaa et al., 2010 Kazakovaa et al., 2010 Kloos & Zein, 1993 Kloos & Zein, 1993 Gonzalez et al., 1992 E coli and P syringae Table 3 Bactericidal activity of triterpene derivatives (contd.) - Takechi & Tanaka, 1993 Takechi & Tanaka, 1993 Mallavadhani et al., 2004 Relationships Between Chemical... rossii Maesa lanceolata B subtilis and S aureus B subtilis MRSA, quinolone resistance S aureus (QRSA), and S aureus MRSA, QRSA, and S aureus MRSA, QRSA, and S aureus MRSA, QRSA, and S aureus S aureus Activity against Gramnegative bacteria Chlamydia pneumoniae E coli and P aeruginosa E coli - - Ref Dehaen et al., 2011 Semwal et al., 2011 Nick et al., 1994 Zheng et al., 2008 Zheng et al., 2008 Zheng et al.,... Chouhan & Singh, 2010 Sanches et al., 2005 Nickavar & Mojab, 2003 Kuete et al., 2006 Devmurari et al., 2010 Hess et al., 1995 Table 1 Vegetal species that exhibit bactericidal activity and contain triterpenes (contd.) 4 A Search for Antibacterial Agents Some plants exhibit a broad spectrum of activity against both Gram-positive and Gramnegative bacteria and contain other chemical classes, such as coumarins,... enzymatic cleavage of DNA (Kanaras et al 2007) This process is designed to monitor the enzymatic cleavage activity based on the wave length shifting of Au nanoparticles Jena and Raj have developed an optical method for the sensing of biomedically important polyionic drugs, protamine and heparin based on the * Corresponding Author 26 A Search for Antibacterial Agents assembly/disassembly of Au nanoparticles... gingivalis, and S typhi E coli, P aeruginosa, and S typhi Oleanolic acid (14) Periplaca laevigata Oleanolic acid acetate (15) Periplaca laevigata Maslinic acid acetate (16) Periplaca laevigata S aureus Methyl 3-acetyloleanolic acid (17) Vitis vinifera S mutans Methyl oleanolic acid (18) Vitis vinifera S mutans P.gingivalis Oleanolic acid 28-O-[β-Dglucopyranosyl] Ester (19) 1α,3β-Dihydroxyolean-12-en-29-oic acid . A SEARCH FOR ANTIBACTERIAL AGENTS Edited by Varaprasad Bobbarala A Search for Antibacterial Agents Edited by Varaprasad Bobbarala Published by InTech Janeza. book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechopen.com A Search for Antibacterial Agents, Edited by Varaprasad Bobbarala p. cm. ISBN. and G. M. Corr a Chapter 2 Flower Shaped Silver Nanostructures: An Efficient Bacteria Exterminator 25 Subash Chandra Sahu, Barada Kanta Mishra and Bikash Kumar Jena Chapter 3 Lutamide, a
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