stiffness The renal criteria now include measurement of proteinuria by the urine protein/creatinine ratio without the requirement of a time frame for collection In contrast to the older ACR criteria that included only seizures or psychosis as neurologic manifestations of disease, the new criteria include many other neurologic manifestations, including myelitis, peripheral or cranial neuropathy, mononeuritis multiplex, and acute confusional state The hematologic criteria have been subdivided into three categories: hemolytic anemia, thrombocytopenia (