... inhibitgrowth of the strain even in the presence of IPTGinduction. All of these results suggest that the low geneexpression associated with NGG codons in the down-stream region following the initiation ... paus-ing at early NGG codons is the reason for the observed low gene expression. The length of the peptidyl moiety of the peptidyl-tRNA in uences the drop- off process in the case ofvery small mini-genes ... codondependent peptidyl-tRNA drop- off at the very begin-ning of the coding region in mRNA. In the case ofNGG codons located close to the initiation codon suchinstability appears to be even...