... Identification of the transcription start sites. The upstreamregion of the HO-2 gene is shown. Exon 1 encodes the untranslated region, and exon 2 encodes the protein-coding region (closed box),including ... degrada-tion in the population of hemoglobin-positive cells.To the best of our knowledge, there has been noreport on the promoter function of the human HO-2Fig. 7. Characterization of the human ... such as the active degradation of HO-1 pro-tein, might ensure constant or reduced expressionlevels of HO-1 protein in these cell lines under hypo-xia. In contrast, the expression levels of HO-1...