... genome sequencingstarted to cover the entire genetic information ofseveral species. This information is now available for aKeywords activity- based probe; ATP-binding proteins;COFRADIC; diagonal ... Additionally, we discuss an activity- based proteome study in which purine-binding proteins were pro-filed by diagonal chromatography.AbbreviationsABP, activity- based probe; COFRADIC, combined ... 96, 14694–14699.74 Kumar S, Zhou B, Liang F, Wang WQ, Huang Z &Zhang ZY (2004) Activity- based probes for proteintyrosine phosphatases. Proc Natl Acad Sci USA 101,7943–7948.75 Wyatt JL...