... PAI -1 , plasminogen activator inhibitor -1 ; s, b-strand;S-2444, pyro-Glu-Gly-Arg-p-nitroanilide; uPA, urokinase-typeplasminogen activator; VN, vitronectin; wt, wild-type; XR 511 8,((3Z,6Z )-6 -benzylidene- 3-( 5-( (2-dimethylaminoethyl-thio )- 2-thienyl)methylene-2,5-piperazinedione ... respectto the affinity to Mab -1 : Q57/73A, Q59/75A, Q 61/ 77A, K67/83A, K106 /12 5A, Q109 /12 8A, D299/ 310 A, R302/ 313 A, F304/ 315 A, Q305/ 316 A,T309/ 319 A, D 313 /323A, Q 314 /324A, E 315 /325A, P 316 /326A, K325/335A.Substitution(s)Secondary ... activity to Mab -1 : Q57/73A, Q59/75A, Q 61/ 77A, K67/83A, K106 /12 5A, Q109 /12 8A,R302/ 313 A, F304/ 315 A, Q305/ 316 A, T309/ 319 A, D 313 /323A, Q 314 /324A, E 315 /325A, P 316 /326A, K325/335A. 16 76 J. S. Bødker...